scholarly journals Soy Intake and Risk of Type 2 Diabetes Among Japanese Men and Women: JACC Study

2022 ◽  
Vol 8 ◽  
Author(s):  
Fangyu Yan ◽  
Ehab S. Eshak ◽  
Kokoro Shirai ◽  
Jia-Yi Dong ◽  
Isao Muraki ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Inverse Association ◽  
Protective Effects ◽  
Dietary Intakes ◽  
Japanese Men ◽  
Men And Women ◽  
Overweight Women ◽  
Soy Foods ◽  
A Prospective Study

The evidence on the protective effects of soy foods against type 2 diabetes has been inconsistent. We thought to examine the association between the dietary intakes of soy and the risk of diabetes in a prospective study encompassing 21,925 healthy Japanese men and women aged 40–79 years. A validated self-administered food frequency questionnaire determined the intakes of soy, and their associations with risk of type 2 diabetes were evaluated by the logistic regression analysis. During the 5-year follow-up period, we observed 593 new cases of type 2 diabetes (302 in men and 291 in women). There was no association between dietary intakes of soy foods and the risk of type 2 diabetes among men. Whereas among women, higher tofu intake was inversely associated with risk of type 2 diabetes; the multivariable odds ratios (ORs) of type 2 diabetes were 0.92 (95% CI: 0.69–1.21) for 3–4 times per week and 0.67 (95% CI: 0.49–0.94) for almost daily (p-trend = 0.03) in reference to those consuming tofu less than 3 times per week. Intakes of boiled beans and miso soup were not associated with the risk in both genders. The inverse association tended to be more evident among overweight women and postmenopaused women. In conclusion, the frequency of tofu intake was inversely associated with the risk of type 2 diabetes among women.

scholarly journals Biomarkers of Vascular Injury and Type 2 Diabetes: A Prospective Study, Systematic Review and Meta-Analysis

2019 ◽  
Vol 8 (12) ◽  
pp. 2075 ◽  
Author(s):  
Laura Pletsch-Borba ◽  
Cora Watzinger ◽  
Renée Turzanski Fortner ◽  
Verena Katzke ◽  
Lukas Schwingshackl ◽  
...  
Keyword(s):  
Systematic Review ◽  
Type 2 Diabetes ◽  
Vascular Injury ◽  
Prospective Studies ◽  
Meta Analysis ◽  
Positive Association ◽  
Intercellular Adhesion Molecule ◽  
Inverse Association ◽  
A Prospective Study

Data on biomarkers of vascular injury and type 2 diabetes (T2D) risk from prospective studies are lacking. We evaluated seven biomarkers of vascular injury in relation to T2D. Additionally, a meta-analysis was performed. From the EPIC–Heidelberg cohort, 2224 participants were followed-up from baseline for 16 (median) years. E-Selectin, P-Selectin, intercellular adhesion molecule 3 (ICAM3), thrombomodulin, thrombopoietin, glycoprotein IIb/IIIa and fibrinogen levels were measured in baseline blood samples. The systematic review and meta-analysis included prospective studies identified through MEDLINE and Web of Science that investigated the association between mentioned biomarkers and T2D. The study population included 55% women, median age was 50 years, and 163 developed T2D. ICAM3 was associated with lower T2D risk (fully adjusted HRhighest vs. lowest tertile 0.62 (95% CI: 0.43, 0.91)), but no other studies on ICAM3 were identified. Overall, fifteen studies were included in the systematic review and meta-analysis (6,171 cases). E-Selectin was associated with higher T2D risk HRper SD: 1.34 (95% CI: 1.16, 1.54; I2 = 63%, n = 9 studies), while thrombomodulin was associated with lower risk HRper SD: 0.82 (95% CI: 0.71, 0.95; I2 = 0%, n = 2 studies). In the EPIC–Heidelberg, ICAM3 was associated with lower T2D risk. The meta-analysis showed a consistent positive association between E-Selectin and T2D. It was also suggestive of an inverse association between thrombomodulin and T2D, although further studies are needed to corroborate this finding.

scholarly journals Cigarette Smoking and Risk of Type 2 Diabetes Mellitus among Middle-aged and Elderly Japanese Men and Women

2004 ◽  
Vol 160 (2) ◽  
pp. 158-162 ◽  
Author(s):  
T. Sairenchi ◽  
H. Iso ◽  
A. Nishimura ◽  
T. Hosoda ◽  
F. Irie ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cigarette Smoking ◽  
Middle Aged ◽  
Japanese Men ◽  
Men And Women ◽  
Elderly Japanese

scholarly journals Among the water-soluble vitamins, dietary intakes of vitamins C, B2 and folate are associated with the reduced risk of diabetes in Japanese women but not men

2019 ◽  
Vol 121 (12) ◽  
pp. 1357-1364 ◽  
Author(s):  
Ehab S. Eshak ◽  
Hiroyasu Iso ◽  
Isao Muraki ◽  
Akiko Tamakoshi
Keyword(s):  
Type 2 Diabetes ◽  
Smoking Status ◽  
Japanese Women ◽  
Water Soluble ◽  
Dietary Intakes ◽  
Family History Of Diabetes ◽  
History Of ◽  
A Prospective Study ◽  
Reduced Risk

AbstractRecent studies have shown that micronutrients are involved in the pathology of type 2 diabetes. Antioxidant effects of vitamins C and B2 and homocysteine-lowering effects of vitamins B6, folate and B12 may have protective roles. However, a few reports have investigated the association between dietary water-soluble vitamin intakes and risk of diabetes. In a prospective study encompassing 19 168 healthy Japanese men and women aged 40–79 years, we examined the associations between dietary intakes of water-soluble vitamins, determined by a validated self-administered FFQ, with the risk of 5-year cumulative incidence of type 2 diabetes by using the logistic regression model. Within the 5-year period, there were 494 self-reported new cases of diabetes. Higher dietary intakes of vitamins C, B2 and folate were associated with lower risk of incident diabetes only in women, whereas no associations of dietary intakes of vitamins B1, B3, B5, B6 and B12 were observed in either sex. The multivariable OR in the highest v. the lowest quartile of intakes among women were 0·61 (95 % CI 0·44, 0·94; P-trend = 0·04) for vitamin C, 0·56 (95 % CI 0·34, 0·93; P-trend = 0·03) for vitamin B2 and 0·70 (95 % CI 0·46, 0·98; P-trend = 0·03) for folate. Other than that for sex (P < 0·05), the P-interactions with age, BMI, smoking status or having a family history of diabetes were >0·10. In conclusion, higher dietary intakes of vitamins C, B2 and folate, but not other water-soluble vitamins, were associated with reduced risk of type 2 diabetes in Japanese women.

scholarly journals Low-Carbohydrate Diet and Type 2 Diabetes Risk in Japanese Men and Women: The Japan Public Health Center-Based Prospective Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (2) ◽  
pp. e0118377 ◽  
Author(s):  
Akiko Nanri ◽  
Tetsuya Mizoue ◽  
Kayo Kurotani ◽  
Atsushi Goto ◽  
Shino Oba ◽  
...  
Keyword(s):  
Public Health ◽  
Type 2 Diabetes ◽  
Prospective Study ◽  
Health Center ◽  
Carbohydrate Diet ◽  
Japanese Men ◽  
Men And Women ◽  
Low Carbohydrate Diet ◽  
Low Carbohydrate

scholarly journals Association of Habitual Coffee Consumption and HECTD4 Polymorphism with Risk of Prediabetes and Type 2 Diabetes (P18-071-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Taiyue Jin ◽  
Jiyoung Youn ◽  
Moonil Kang ◽  
Joohon Sung ◽  
Jung Eun Lee ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Association Studies ◽  
Coffee Consumption ◽  
Tolerance Test ◽  
Self Report ◽  
Oral Glucose ◽  
Genome Wide Association Studies ◽  
Inverse Association ◽  
Men And Women

Abstract Objectives Epidemiological studies suggested the evidence that coffee consumption decreased risk of type 2 diabetes. Recently, Japanese genome-wide association studies (GWAS) of coffee consumption has identified rs2074356 (G > A) at 12q24.12–13 in HECTD4. This study aims to examine the associations of habitual coffee consumption with prediabetes and type 2 diabetes, and whether this association is modified by rs2074356 variant in Korean adults. Methods A total of 4010 participants (1890 men and 2120 women) who had genetic information from Korea Association REsource (KARE) study were included. Habitual coffee consumption was assessed through a food frequency questionnaire and categorized into five categories (non-consumers, <1 cup/day and ≥1 cups/day of black coffee, and <1 cup/day and ≥1 cups/day of sugared coffee). Incident prediabetes or type 2 diabetes were defined according to the self-report of physician-diagnosis, oral glucose tolerance test (OGTT) or hemoglobin A1c (HbA1c) test. Multivariable logistic regression models were used to calculate odds ratio (OR)s and 95% confidence interval (CI)s. Results A total of 2916 participants (72.7%) have developed prediabetes during a follow-up of 15 years. We found that black coffee consumption lowered risk of prediabetes and type 2 diabetes combined among men and women combined (OR = 0.63; 95% CI = 0.44–0.91 for ≥1 cups/day black coffee vs. non-consumers). When we separated men and women, compared with non-consumers, ORs (95% CIs) for ≥1 cups/day of black coffee were 0.50 (0.27–0.93) among men and 0.72 (0.45–1.14) among women and ORs (95% CIs) for ≥1 cups/day of sugared coffee were 1.41 (0.91–2.18) among men and 1.12 (0.80–1.58) among women. We observed a suggestive difference by rs2074356 (GG vs. AG + AA). Compared with non-consumers, participants with AG + AA genotypes consumed ≥ 1 cups/day of black coffee had a 60% lower risk of prediabetes and type 2 diabetes combined (95% CI 0.20–0.78), but we found a weaker association among those with GG genotype (OR = 0.81; 95% CI = 0.51–1.28). Conclusions We observed an inverse association between black coffee consumption and prediabetes and type 2 diabetes combined in Korean population. This association was more pronounced among carriers of minor allele of HECTD4 rs2074356 (AG/AA). Funding Sources None.

Association of Muscle-Strengthening Training with Risk of Type 2 Diabetes in Japanese Men and Women.

2015 ◽  
Vol 44 (suppl_1) ◽  
pp. i281-i281
Author(s):  
K. Kuwahara ◽  
T. Honda ◽  
S. Yamamoto ◽  
T. Nakagawa ◽  
K. Kurotani ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Japanese Men ◽  
Men And Women ◽  
Muscle Strengthening
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