scholarly journals Diagnostic Utility of Radiomics in Thyroid and Head and Neck Cancers

2021 ◽  
Vol 11 ◽  
Author(s):  
Maryam Gul ◽  
Kimberley-Jane C. Bonjoc ◽  
David Gorlin ◽  
Chi Wah Wong ◽  
Amirah Salem ◽  
...  

Radiomics is an emerging field in radiology that utilizes advanced statistical data characterizing algorithms to evaluate medical imaging and objectively quantify characteristics of a given disease. Due to morphologic heterogeneity and genetic variation intrinsic to neoplasms, radiomics have the potential to provide a unique insight into the underlying tumor and tumor microenvironment. Radiomics has been gaining popularity due to potential applications in disease quantification, predictive modeling, treatment planning, and response assessment – paving way for the advancement of personalized medicine. However, producing a reliable radiomic model requires careful evaluation and construction to be translated into clinical practices that have varying software and/or medical equipment. We aim to review the diagnostic utility of radiomics in otorhinolaryngology, including both cancers of the head and neck as well as the thyroid.

2012 ◽  
Vol 2 (4) ◽  
pp. 42-53 ◽  
Author(s):  
Vandana Ahuja

The internet provides opportunities for marketing which extend from the micro level of electronic contacts to the macro level of new business opportunities. As the democratisation of consumer expression leads to a viral proliferation of information online, the new age communication ecosystem has prompted the need for a careful evaluation of the potential of what is being called Consumer Generated internet content, creating new challenges for Marketing Intelligence. These offerings of the Information age have garnered adequate potential to engineer business transformations. Consumer Generated Media (CGM) comprises the content generated by consumers within online venues such as Internet forums, Blogs, Wikis, discussion lists, etc. Leveraging CGM and channelizing it appropriately has become critical for organisations for understanding and managing market performance, product positioning, and driving brand reputations. The biggest challenge in front of organizations now is to harvest CGM to help marketers gain insight into the online market conversations taking place. Efforts are on by marketing in organizations to track the volume, origin, flow, and trajectory of the conversations in real time as they evolve, study the domain of Individual Internet Worth and map the scope, reach and influence of the same on topics that might have a positive or negative impact on a company’s products, promotions, and reputation.


2019 ◽  
Vol 51 (1) ◽  
pp. 93-107
Author(s):  
Olena Shelest-Szumilas

The article addresses selected issues related to the migrant employment in Poland. It offers insight into the most important trends in the situation of migrant workers in the Polish labor market and discusses how observable changes will influence human resources management. The article begins with an overview of general situation of migrants in the labor market in Poland, which is based on the analysis of available statistical data. The second chapter presents and discusses briefly the potential challenges for human resources management in Polish enterprises.


2020 ◽  
Vol 11 (10) ◽  
pp. 637-651 ◽  
Author(s):  
Swatantra Shrivastava ◽  
Ravleen Nagi ◽  
Saurabh Sharma ◽  
Sajid Ahmed Rasul Sanadi ◽  
Elbadri Taha Dafallah ◽  
...  

Cancer is a major public health burden worldwide, affecting millions of people each year. One of the major hallmarks of cancer is rapid growth and progression by evasion of host immune responses. Tumor resistance to conventional anticancer drugs by several mechanisms, such as drug inactivation, efflux pumps and enhanced toxicity to normal cells decreases their clinical efficacy. These limitations resulted in the development of new targeted agents, such as monoclonal antibodies and small molecule inhibitors that have high tumor specificity. This paper discusses the therapeutic applications of novel molecular targeted agents and immunotherapy as an alternative treatment option for head and neck cancers, as well as provides insight into future therapeutic approaches for advanced head and neck cancers.


2018 ◽  
Vol 159 (4) ◽  
pp. 669-674 ◽  
Author(s):  
Amy M. Manning ◽  
Keith A. Casper ◽  
Kay St. Peter ◽  
Keith M. Wilson ◽  
Jonathan R. Mark ◽  
...  

2017 ◽  
Vol 16 (02) ◽  
pp. 061-071
Author(s):  
Reza Forghani

AbstractDual-energy computed tomography (DECT) is an advanced form of computed tomography (CT), in which image acquisition is performed at two different energy spectra, instead of a single-energy spectrum using conventional single-energy CT (SECT). This enables the creation of different reconstructions and quantitative spectral tissue analysis beyond what is possible with SECT. In adults, there are increasing clinical applications of DECT for all organ systems, including neuroimaging and head and neck imaging. However, there are relatively few studies evaluating applications of DECT for pediatric imaging and little to none in neuroimaging or head and neck imaging. The purpose of this article is to provide an overview and familiarize the readers with DECT. This article will review the fundamental principles behind DECT, including different DECT acquisition systems and principles of DECT material characterization. This will be followed by a review of potential applications of DECT, many based on imaging the head and neck. The objectives are to familiarize the readers with this exciting technology and hopefully serve as a primer for investigations and applications of DECT for pediatric neuro and head and neck imaging.


2005 ◽  
Vol 59 (3) ◽  
pp. 215-234
Author(s):  
Joris van Eijnatten

For a proper understanding of theology, an insight into the social and professional context in which it arises is at least as important as an appraisal of its content. This article examines the theological knowledge generated by a group of eighteenth and nineteenth-century academics represented by Johannes Hendrik van der Palm (1763‐1840), one of the leading theologians of his generation. Using (among other things) statistical data concerning the knowledge produced by these theologians, a sketch is offered of the social and scholarly environment in which their theology arose. It is demonstrated that the credibility of theological knowledge is to a large extent dependant on the means by, and the circumstances in which, such knowledge is produced.


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