Trends in Intracranial Glioma Incidence and Mortality in the United States, 1975-2018

PurposeGlioma incidence in the US seems to have stabilized over the past 20 years. It’s also not clear whether changes in glioblastoma incidence are associated with glioma mortality trends. Our study investigated trends in glioma incidence and mortality according to tumor characteristics.MethodsThis study obtained data from the Surveillance, Epidemiology, and End Results-9 (SEER-9) registries to calculate glioma incidence and mortality trends. Annual percent changes (APC) and 95% CIs were calculated using the Joinpoint program.Results62,159 patients (34,996 males and 55,424 whites) were diagnosed with glioma during 1975-2018, and 31,922 deaths occurred from 1995-2018. Glioblastoma (32,893 cases) and non-glioblastoma astrocytoma (17,406 cases) were the most common histologic types. During the study period, the incidence of glioma first experienced a significant increase (APC=1.8%, [95% CI, 1.3% to 2.3%]) from 1975 to 1987, and then experienced a slight decrease (APC=-0.4%, [95% CI, -0.5% to -0.3%]) from 1987 to 2018, while the APC was 0.8% for glioblastoma, -2.0% for non-glioblastoma astrocytoma, 1.1% for oligodendroglial tumors, 0.7% for ependymoma and -0.3% for glioma NOS during the study period. Glioblastoma incidence increased for all tumor size and tumor extension except for distant. From 1995 to 2018, glioma mortality declined 0.4% per year (95% CI: -0.6% to -0.2%) but only increased in patients older than 80 years [APC=1.0%, (95% CI, 0.4% to 1.6%)].ConclusionSignificant decline in glioma incidence (1987-2018) and mortality (1995-2018) were observed. Epidemiological changes in non-glioblastoma astrocytoma contributed the most to overall trends in glioma incidence and mortality. These findings can improve understanding of risk factors and guide the focus of glioma therapy.

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Abstract MP38: Intracerebral Hemorrhage Across the United States: Incidence and Mortality Trends From 1990 to 2017

Stroke ◽

10.1161/str.52.suppl_1.mp38 ◽

2021 ◽

Vol 52 (Suppl_1) ◽

Author(s):

Augustin DeLago ◽

Harpreet Singh ◽

Arashdeep Rupal ◽

Chinmay Jani ◽

Arshi Parvez ◽

...

Keyword(s):

United States ◽

Intracerebral Hemorrhage ◽

Vitamin K Antagonists ◽

Oral Anticoagulants ◽

Direct Oral Anticoagulants ◽

The United States ◽

Mortality Trends ◽

Reversal Agents ◽

Incidence And Mortality ◽

The Us

Background: Intracerebral Hemorrhage (ICH) accounts for 10% of strokes annually in the United States (US). Up-to-date trends in disease burden and regional variation remain unknown; especially after a dramatic increase in the use of direct oral anticoagulants (DOACs) since 2010. Our study reports updated incidence, mortality and mortality to incidence ratio (MIR) data related to ICH across the US. Methods: This observational study utilized the Global Burden of Disease database to determine age-standardized incidence (ASIR), death (ASDR) and MIR rates for ICH overall and for each state in the US from 1990-2017. All analyses were stratified by sex. Trends were analyzed using Joinpoint regression analysis, with presentation of estimated annual percentage changes (EAPCs) in ASIRs, ASDRs and MIRs over the observation period. Results: We observed an overall decrease in ASIRs, ASDRs and MIRs in both genders from 1990-2017, apart from female ASIRs and ASDRs in West Virginia and Kentucky. In 2017, the mean ASIR per 100,000 population for men was 25.67 and 19.17 for women. The 2017 mean ASDRs per 100,000 population for men and women were 13.96 and 11.35, respectively. The District of Columbia had the greatest decreases in ASIR EAPCs for males at -41.25% and females at -40.58%, and the greatest decreases in ASDR EAPCs for both males and females at -55.38% and -48.51%, respectively. The overall MIR during the study period decreased in males by -12.12% and females by -7.43%. However, MIR increased in males from 2014-2017 (EAPC +2.2% [95% CI +0.9%-+3.5%]) and in females from 2011-2017 (EAPC +1.0% [CI +0.7%-+1.4%]). Conclusion: This report reveals overall decreasing trends in incidence, mortality and MIR from 1990-2017. Notably, no significant change in mortality was found in the last 6 years of the study period, and MIR worsened in males from 2014-2017 and in females from 2011-2017, suggesting decreased ICH related survival lately. The substitution of vitamin K antagonists with DOACs is one possible explanation for a downtrend in incidence despite an aging population and increased use of anticoagulants. Limited access to reversal agents for DOACs is a potential reason for increase in MIR, however concrete deductions cannot be made owing to the observational nature of the study.

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The Riddle of a Common History

Journal of Educational Media Memory and Society ◽

10.3167/jemms.2009.010107 ◽

2009 ◽

Vol 1 (1) ◽

pp. 93-116 ◽

Cited By ~ 2

Author(s):

Mauricio Tenorio-Trillo

Keyword(s):

United States ◽

Common Ground ◽

The United States ◽

History Textbooks ◽

Recent History ◽

History Textbook ◽

The Past ◽

The Us ◽

Constant Part ◽

Intrinsic Component

By identifying two general issues in recent history textbook controversies worldwide (oblivion and inclusion), this article examines understandings of the United States in Mexico's history textbooks (especially those of 1992) as a means to test the limits of historical imagining between U. S. and Mexican historiographies. Drawing lessons from recent European and Indian historiographical debates, the article argues that many of the historical clashes between the nationalist historiographies of Mexico and the United States could be taught as series of unsolved enigmas, ironies, and contradictions in the midst of a central enigma: the persistence of two nationalist historiographies incapable of contemplating their common ground. The article maintains that lo mexicano has been a constant part of the past and present of the US, and lo gringo an intrinsic component of Mexico's history. The di erences in their historical tracks have been made into monumental ontological oppositions, which are in fact two tracks—often overlapping—of the same and shared con ictual and complex experience.

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Abstract P183: 20-year Secular Trend of Cardiovascular Disease Comorbidities in the United States, 1997-2016

Circulation ◽

10.1161/circ.137.suppl_1.p183 ◽

2018 ◽

Vol 137 (suppl_1) ◽

Author(s):

Dianjianyi Sun ◽

Tao Zhou ◽

Xiang Li ◽

Yoriko Heianza ◽

Xiaoyun Shang ◽

...

Keyword(s):

Cardiovascular Disease ◽

Secular Trend ◽

Adult Population ◽

The United States ◽

The Past ◽

The Us ◽

Metabolic Conditions ◽

Respiratory Conditions ◽

The U.S ◽

Chronic Comorbidities

Background: Cardiovascular disease (CVD) has been the number one cause of death and disability in the US and globally for decades, and its comorbidity complicates the management of CVD. However, little is known about the secular trend of CVD comorbidities in national representative populations in the last 20 years. Methods: Prevalence of CVD and nine major chronic comorbidities was estimated using data from 1,324,214 adults aged 18 years and older in the National Health Interview Survey (NHIS) from 1997 through 2016, with age-standardized to the U.S. population in the year 2000. Results: CVD prevalence in the US adult population significantly declined in the past twenty years (from 6.6% in 1997 to 5.9% in 2016, P trend <0.01in Figure a). And such trend was shown in women and whites (P trend <0.01), but not in men and blacks (P trend >0.05). We ranked the nine major chronic comorbidities (high to low) in the CVD patients (Figure b.), including (1) hypertension, (2) respiratory conditions, (3) nervous system conditions, (4) digestive conditions, (5) diabetes, (6) cancer, (7) genitourinary conditions, (8) circulatory conditions, and (9) endocrine/nutritional/metabolic conditions. From 1997 to 2016, the prevalence of CVD comorbidities including hypertension (38.8% to 50.2%), digestive conditions (17.0% to 27.1%), diabetes (10.0% to 19.2%), cancer (9.4% to 12.8%), and genitourinary conditions (4.1% to 5.2%) continuingly increased (all P trend <0.01), while respiratory conditions declined (35.9% to 27.6%, P trend <0.01). Similar trends of CVD comorbidities were observed among subgroups stratified by gender or by race. Conclusions: CVD prevalence in the U.S. adults have declined significantly in the past two decades, but rates of CVD comorbidities including hypertension, digestive conditions, diabetes, cancer, and genitourinary conditions increased substantially.

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Before American History: Nationalist Mythmaking and Indigenous Dispossession

10.52156/m.5619 ◽

2021 ◽

Author(s):

Christen Mucher

Keyword(s):

Knowledge Production ◽

American History ◽

New Spain ◽

The United States ◽

Material Base ◽

Historical Knowledge ◽

The Past ◽

British America ◽

The Us ◽

Ruling Elites

Before American History examines the project of settler nationalism from the 1780s to the 1840s in two of North America’s republics—the US and Mexico—through an analysis of historical knowledge production. As the US and Mexico transformed from European colonies into independent republics—and before war scarred them both—antiquarians and historians compiled and interpreted archives meant to document America’s Indigenous pasts. Before American History approaches two iconic imaginings of the past—the carved Sun Stone and the mounded earthwork—as archives of nationalist power and Indigenous dispossession as well as objects that are, at their material base, Indigenously-produced but settler-controlled and settler-interpreted. In making the connection between earthworks built by an allegedly vanished people merely peripheral to US citizens and the literal touchstone of Mexicans’ history, Before American History details how Mexican and US nationalists created national histories out of Indigenous pasts and thereby wrote Indigenous pasts out of their national histories and out of national lands. It uncovers how the manipulation of Indigenous pasts and (mis)interpretations of “American Antiquities”—Indigenous documents, objects and monuments—served the purposes of a trans-imperial/transnational network of creole ruling elites, first in New Spain and British America, and later in Mexico and the United States, as they struggled to construct new political, geographic, and historical orders.

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Cancer Incidence and Mortality Trends Among Whites in the United States, 1947–84

JNCI Journal of the National Cancer Institute ◽

10.1093/jnci/79.4.701 ◽

1987 ◽

Cited By ~ 1

Keyword(s):

United States ◽

Cancer Incidence ◽

The United States ◽

Mortality Trends ◽

Incidence And Mortality

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Fungicide Sensitivity of U.S. Genotypes of Phytophthora infestans to Six Oomycete-Targeted Compounds

Plant Disease ◽

10.1094/pdis-05-14-0452-re ◽

2015 ◽

Vol 99 (5) ◽

pp. 659-666 ◽

Cited By ~ 35

Author(s):

Amanda Saville ◽

Kim Graham ◽

Niklaus J. Grünwald ◽

Kevin Myers ◽

William E. Fry ◽

...

Keyword(s):

United States ◽

Phytophthora Infestans ◽

The United States ◽

Effective Concentration ◽

Response Curves ◽

Baseline Sensitivity ◽

Fungicide Sensitivity ◽

The Past ◽

The Us

Phytophthora infestans causes potato late blight, an important and costly disease of potato and tomato crops. Seven clonal lineages of P. infestans identified recently in the United States were tested for baseline sensitivity to six oomycete-targeted fungicides. A subset of the dominant lineages (n = 45) collected between 2004 and 2012 was tested in vitro on media amended with a range of concentrations of either azoxystrobin, cyazofamid, cymoxanil, fluopicolide, mandipropamid, or mefenoxam. Dose-response curves and values for the effective concentration at which 50% of growth was suppressed were calculated for each isolate. The US-8 and US-11 clonal lineages were insensitive to mefenoxam while the US-20, US-21, US-22, US-23, and US-24 clonal lineages were sensitive to mefenoxam. Insensitivity to azoxystrobin, cyazofamid, cymoxanil, fluopicolide, or mandipropamid was not detected within any lineage. Thus, current U.S. populations of P. infestans remained sensitive to mefenoxam during the displacement of the US-22 lineage by US-23 over the past 5 years.

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Rethinking of Turkey’s Geopolitics together with Eastern Mediterranean. Turkish Perspective

Kwartalnik "Bellona" ◽

10.5604/01.3001.0015.0340 ◽

2021 ◽

Vol 705 (2) ◽

pp. 45-66

Author(s):

Arıboğan Deniz Ülke ◽

Ibrahim Arslan

Keyword(s):

Middle East ◽

Raw Materials ◽

Eastern Mediterranean ◽

International System ◽

The United States ◽

The Past ◽

Humanitarian Interventions ◽

The Us ◽

Transportation Accessibility ◽

The Eu

In the studies carried out within the scope of geopolitical discipline, the expression "geography is destiny" is frequently used and it is claimed that geography has unchangeable, irreversible qualities and the policies implemented are shaped through this assumption. This assumption ignores the humanitarian interventions over the geography and makes it difficult to understand the results produced by these interventions at both regional and global level. Similarly, the dynamic nature of international relations reveals new actors in the international system in times of bounce and collapse, and the borders that expand or narrow with each transformation can differentiate the geopolitical view with new sovereign countries. In the historical process, transportation accessibility, trade, search for raw materials, security and alliance relations have caused the same geography to be interpreted differently in different periods. This situation also applies to the geography of Turkey had been the homeland of empires. The developments in the Middle East over the past two decades has created a sensitivity in the relations between Turkey and the West, especially the United States. Competing interests with the EU and the US in the Middle East and the Eastern Mediterranean, has necessitated a reassessment of Turkey's geography.

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Population Issues and Reproductive Politics

Reproductive Politics ◽

10.1093/wentk/9780199811403.003.0006 ◽

2013 ◽

Author(s):

Rickie Solinger

Keyword(s):

United States ◽

Population Growth ◽

The United States ◽

The State ◽

Reproductive Politics ◽

The Past ◽

United States Today ◽

The Us

What is the state of population growth in the United States today, and how is it affected by immigration? According to the 2010 census, the US population has grown 9.7 percent (adding about 27 million people, including about 13 million immigrants) during the past...

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An Act of War? The Interview Affair, the Sony Hack, and the Hollywood–Washington Power Nexus Today

Journal of American Studies ◽

10.1017/s0021875817000512 ◽

2017 ◽

Vol 53 (1) ◽

pp. 1-27

Author(s):

TONY SHAW ◽

TRICIA JENKINS

Keyword(s):

The United States ◽

Global Market ◽

Us Foreign Policy ◽

First Century ◽

The Other ◽

State Security ◽

The Past ◽

Early Twenty ◽

The Us ◽

The One

Film has been an integral part of the propaganda war fought between the United States and North Korea over the past decade. The international controversy surrounding the Hollywood comedy The Interview in 2014 vividly demonstrated this and, in the process, drew attention to hidden dimensions of the US state security–entertainment complex in the early twenty-first century. Using the emails leaked courtesy of the Sony hack of late 2014, this article explores the Interview affair in detail, on the one hand revealing the close links between Sony executives and US foreign-policy advisers and on the other explaining the difficulties studios face when trying to balance commercial and political imperatives in a global market.

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