Mental Health in COVID-19 Pandemic: A Meta-Review of Prevalence Meta-Analyses

Background: Mental health burden has been massively reported during the COVID-19 pandemic period. Aiming to summarise these data, we present a meta-review of meta-analyses that evaluated the impact of COVID-19 pandemic on anxiety, depressive and stress symptoms, psychological distress, post-traumatic stress disorder/symptoms (PTSD), and sleep disturbance, reporting its prevalence on general public (GP) and health care workers (HCW).Methods: A search was performed in the PubMed, EMBASE, and the Web of Science. Sleep disturbances, psychological distress, stress, and burnout were grouped as “Psychophysiological stress,” and anxiety, depression, and PTSD were grouped as “Psychopathology.” A random-effects model, calculating the pooled prevalence together with 95% confidence interval was performed for each domain. Subgroup analyses were performed for each population type (GP and HCW) and for each mental health outcome. For anxiety and depression, subgroup analysis for population type was performed. Heterogeneity is reported as I2. Publication bias was assessed through visual inspection of the funnel plot, and further tested by Egger's test and trim and fill analyses.Results: A total of 18 meta-analyses were included. The prevalence of psychophysiological stress was 31.99% (CI: 26.88–37.58, I2 = 99.9%). HCW showed a higher prevalence (37.74%, CI: 33.26–42.45, I2 = 99.7%) than the GP (20.67%, 15.07–27.66, I2 = 99.9%). The overall prevalence of insomnia, psychological distress, and stress were, respectively, 32.34% (CI: 25.65–39.84), 28.25% (CI: 18.12–41.20), and 36% (CI: 29.31–43.54). Psychopathology was present at 26.45% (CI: 24.22–28.79, I2 = 99.9%) of the sample, with similar estimates for population (HCW 26.14%, CI: 23.37–29.12, I2 = 99.9%; GP: 26.99%, CI: 23.41–30.9, I2 = 99.9%). The prevalence of anxiety, depression, and PTSD was 27.77% (CI: 24.47–31.32), 26.93% (CI: 23.92–30.17), and 20% (CI: 15.54–24.37), respectively. Similar proportions between populations were found for anxiety (HCW = 27.5%, CI: 23.78–31.55; GP = 28.33%, CI: 22.1–35.5) and depression (HCW = 27.05%, CI: 23.14–31.36; GP = 26.7%, CI: 22.32–31.59). Asymmetry in the funnel plot was found, and a slight increase in the estimate of overall psychopathology (29.08%, CI: 26.42–31.89) was found after the trim and fill analysis.Conclusions: The prevalence of mental health problems ranged from 20 to 36%. HCW presented a higher prevalence of psychophysiological stress than the general population.Systematic Review Registration:https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=252221, identifier: CRD42021252221.

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Living under siege: resilience, hopelessness, and psychological distress among Palestinian students in the Gaza Strip

Global Mental Health ◽

10.1017/gmh.2021.37 ◽

2021 ◽

Vol 8 ◽

Author(s):

Guido Veronese ◽

Alessandro Pepe ◽

Marwan Diab ◽

Yasser Abu Jamey ◽

Ashraf Kagee

Keyword(s):

Mental Health ◽

Human Rights ◽

Psychological Distress ◽

Mental Disorders ◽

Common Mental Disorders ◽

Gaza Strip ◽

Mental Symptoms ◽

The Gaza Strip ◽

Anxiety Depression ◽

The Impact

Abstract Background Moving from an approach oriented to adaptation and functioning, the current paper explored the network of cumulative associations between the effects of the siege and resilience on mental health. Methods We sought to explore the impact of the siege on psychological distress (anxiety, depression, and stress) and the moderating effect of resilience and hopelessness in a sample of 550 Palestinian university students. We hypothesized that the siege effect would impact psychological distress so that the more people were affected by the siege, the more mental symptoms of common mental disorders they would report. We also expected that the siege would negatively impact both resilience and participants' hopelessness. Results Findings showed that higher scores on the scale measuring effect of the siege were associated with hopelessness. Furthermore, living under siege compromised participants’ resilience. The more the siege affected individuals, the lower resilience were protecting participants mental health and the more hopelessness was exposing them to anxiety, stress, and depression. Conclusion Our findings draw attention to how the ongoing violation of human rights influences people's mental health in Gaza. Implications for clinicians and policymakers are discussed.

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The psychological impact of COVID-19 on the mental health in the general population

QJM ◽

10.1093/qjmed/hcaa201 ◽

2020 ◽

Vol 113 (8) ◽

pp. 531-537 ◽

Cited By ~ 32

Author(s):

G Serafini ◽

B Parmigiani ◽

A Amerio ◽

A Aguglia ◽

L Sher ◽

...

Keyword(s):

Mental Health ◽

Psychological Distress ◽

General Population ◽

Severe Acute Respiratory Syndrome ◽

Psychological Impact ◽

Psychological Reactions ◽

Chinese City ◽

Anxiety Depression ◽

The Impact

Abstract As a result of the emergence of coronavirus disease 2019 (COVID-19) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the Chinese city of Wuhan, a situation of socio-economic crisis and profound psychological distress rapidly occurred worldwide. Various psychological problems and important consequences in terms of mental health including stress, anxiety, depression, frustration, uncertainty during COVID-19 outbreak emerged progressively. This work aimed to comprehensively review the current literature about the impact of COVID-19 infection on the mental health in the general population. The psychological impact of quarantine related to COVID-19 infection has been additionally documented together with the most relevant psychological reactions in the general population related to COVID-19 outbreak. The role of risk and protective factors against the potential to develop psychiatric disorders in vulnerable individuals has been addressed as well. The main implications of the present findings have been discussed.

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A protocol for the systematic review and meta-analysis of thigmotactic behaviour in the open field test in rodent models associated with persistent pain

BMJ Open Science ◽

10.1136/bmjos-2020-100135 ◽

2021 ◽

Vol 5 (1) ◽

pp. e100135

Author(s):

Xue Ying Zhang ◽

Jan Vollert ◽

Emily S Sena ◽

Andrew SC Rice ◽

Nadia Soliman

Keyword(s):

Systematic Review ◽

Outcome Measure ◽

Meta Analysis ◽

Persistent Pain ◽

Effect Sizes ◽

Bias Assessment ◽

Animal Pain ◽

Trim And Fill ◽

Meta Analyses ◽

The Impact

ObjectiveThigmotaxis is an innate predator avoidance behaviour of rodents and is enhanced when animals are under stress. It is characterised by the preference of a rodent to seek shelter, rather than expose itself to the aversive open area. The behaviour has been proposed to be a measurable construct that can address the impact of pain on rodent behaviour. This systematic review will assess whether thigmotaxis can be influenced by experimental persistent pain and attenuated by pharmacological interventions in rodents.Search strategyWe will conduct search on three electronic databases to identify studies in which thigmotaxis was used as an outcome measure contextualised to a rodent model associated with persistent pain. All studies published until the date of the search will be considered.Screening and annotationTwo independent reviewers will screen studies based on the order of (1) titles and abstracts, and (2) full texts.Data management and reportingFor meta-analysis, we will extract thigmotactic behavioural data and calculate effect sizes. Effect sizes will be combined using a random-effects model. We will assess heterogeneity and identify sources of heterogeneity. A risk-of-bias assessment will be conducted to evaluate study quality. Publication bias will be assessed using funnel plots, Egger’s regression and trim-and-fill analysis. We will also extract stimulus-evoked limb withdrawal data to assess its correlation with thigmotaxis in the same animals. The evidence obtained will provide a comprehensive understanding of the strengths and limitations of using thigmotactic outcome measure in animal pain research so that future experimental designs can be optimised. We will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses reporting guidelines and disseminate the review findings through publication and conference presentation.

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The relationship between exclusion from school and mental health: a secondary analysis of the British Child and Adolescent Mental Health Surveys 2004 and 2007

Psychological Medicine ◽

10.1017/s003329171700215x ◽

2017 ◽

Vol 48 (4) ◽

pp. 629-641 ◽

Cited By ~ 12

Author(s):

T. Ford ◽

C. Parker ◽

J. Salim ◽

R. Goodman ◽

S. Logan ◽

...

Keyword(s):

Mental Health ◽

Psychological Distress ◽

Psychiatric Disorder ◽

Health Surveys ◽

Secondary Analysis ◽

Adolescent Mental Health ◽

Child And Adolescent ◽

The Impact ◽

The Relationship

BackgroundChildren with poor mental health often struggle at school. The relationship between childhood psychiatric disorder and exclusion from school has not been frequently studied, but both are associated with poor adult outcomes. We undertook a secondary analysis of the British Child and Adolescent Mental Health Surveys from 2004 and its follow-up in 2007 to explore the relationship between exclusion from school and psychopathology. We predicted poorer mental health among those excluded.MethodPsychopathology was measured using the Strengths and Difficulties Questionnaire, while psychiatric disorder was assessed using the Development and Well-Being Assessment and applying Diagnostic and Statistical Manual of Mental Disorders Fourth Edition (DSM IV) criteria. Exclusion from school and socio-demographic characteristics were reported by parents. Multi-variable regression models were used to examine the impact of individual factors on exclusion from school or psychological distress.ResultsExclusion from school was commoner among boys, secondary school pupils and those living in socio-economically deprived circumstances. Poor general health and learning disability among children and poor parental mental health were also associated with exclusion. There were consistently high levels of psychological distress among those who had experienced exclusion at baseline and follow-up.ConclusionsWe detected a bi-directional association between psychological distress and exclusion. Efforts to identify and support children who struggle with school may therefore prevent both future exclusion and future psychiatric disorder.

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Impact of Postmigration Living Difficulties on the Mental Health of Afghan Migrants Residing in Istanbul

International Journal of Population Research ◽

10.1155/2016/7690697 ◽

2016 ◽

Vol 2016 ◽

pp. 1-8 ◽

Cited By ~ 9

Author(s):

Qais Alemi ◽

Carl Stempel ◽

Kelly Baek ◽

Lisa Lares ◽

Patricia Villa ◽

...

Keyword(s):

Mental Health ◽

Psychological Distress ◽

Idioms Of Distress ◽

Hierarchical Regression ◽

Foreign Countries ◽

Legal Challenges ◽

Culturally Sensitive Interventions ◽

Negative Effect ◽

The Impact ◽

Afghan Migrants

Background. The sociopolitical situation in Afghanistan continually pushes Afghans to seek safety and better socioeconomic prospects in neighboring and foreign countries. In this paper we examine the mental health of Afghan migrants residing in Istanbul, Turkey, an understudied population at high risk of psychopathology. Methods. We surveyed 158 Afghan migrants to assess psychological distress using a culturally grounded measure of mental health, the Afghan Symptom Checklist [ASCL], and used hierarchical regression analysis to examine the impact of postmigration living difficulties (PMLDs) on mental health. Results. We found that depressive, somatoform, anxiety-like symptoms occurred often, as did a number of culturally salient idioms of distress. Regression analyses showed that while socioeconomic variables and poor physical health status significantly predicted psychological distress, PMLDs exerted the strongest negative effect. The most pressing PMLDs for Afghans in Turkey are poverty, unemployment, lack of treatment for health problems, fears of being deported and related legal challenges, and family-related stressors. Conclusion. Our results point to the importance of the critical need to create culturally sensitive interventions to remediate high levels of psychological distress by addressing related PMLD stressors in a highly vulnerable Afghan migrant population residing in Turkey.

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Killing in Combat; the Diverging Mental Health Impact on Distinct Veteran Populations – A Two-Sample Study

10.31234/osf.io/4g9fb ◽

2020 ◽

Author(s):

Andreas Espetvedt Nordstrand ◽

Christer Lunde Gjerstad ◽

Odin Hjemdal ◽

Are Holen ◽

Tore Tveitstul ◽

...

Keyword(s):

Quality Of Life ◽

Mental Health ◽

Psychological Distress ◽

Alcohol Use ◽

Posttraumatic Stress ◽

Armed Forces ◽

Mental States ◽

Two Samples ◽

The Impact

This study examined the warzone stressors: killing in combat, experiencing personal threats, or traumatic witnessing during deployment in relation to psychological distress, alcohol consumption and quality of life at long-term follow-up. The study was conducted in two samples of Norwegian veterans who had served in Afghanistan (Study 1, N = 4,053) or in Lebanon (Study 2, N = 10,605), respectively. Data were collected through two postdeployment mental health surveys conducted by the Norwegian Armed Forces Joint Medical Services. Using linear regressions, we investigated the impact of warzone stressors on posttraumatic stress symptoms, depression, anxiety, insomnia, alcohol use, and quality of life. In study 1 (Afghanistan veterans), killing was not a significant predictor of psychological distress, alcohol use, or quality of life, when controlling for Personal Threats and Witnessing exposure. In study 2 (Lebanon veterans) killing remained a significant predictor (p < .001) of symptoms of posttraumatic stress, depression, and anxiety, after controlling for other warzone stressors. However, killing was not a significant predictor of alcohol use or quality of life in Study 2. In summary, killing in combat may be associated with increased reports of psychological distress, but there were distinct results in the two studies. Differences in mission statements, rules of engagement, and mental states during combat could explain the diverging outcomes. The results indicate that it may be erroneous to ubiquitously regard killing in combat as a moral stressor, and highlight the importance of clear rules of engagements that accounts for the “on the ground” reality of soldiers.

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Impact of COVID-19 on the mental health of healthcare workers in different regions of the world

BJPsych Open ◽

10.1192/bjo.2021.689 ◽

2021 ◽

Vol 7 (S1) ◽

pp. S258-S258

Author(s):

Mahfuja Islam ◽

Philip George ◽

Sindhu Sankaran ◽

Janet Leu Su Hui ◽

Tzun Kit

Keyword(s):

Mental Health ◽

Health Care ◽

Psychological Distress ◽

Healthcare Workers ◽

Well Being ◽

Subjective Assessment ◽

Survey Tool ◽

Frontline Workers ◽

The World ◽

The Impact

AimsThe global health system is facing a serious challenge after the recent outbreak of COVID-19 coronavirus infection which was first identified in Wuhan, China in November 2019 and declared as a pandemic in March 2020 by WHO. There is a wide consensus that this pandemic has negative psychosocial consequences as well as unforeseeable provision of mental health care services and just not on physical health alone. The aim of this research study is to determine the prevalence of psychological distress and to identify the sociodemographic variables with the main attributable factors associated with the psychological distress among healthcare workers and suggestions on how to reduce the impact on the mental health of healthcare workers during the COVID-19 pandemic in different regions of the world.MethodWe performed a cross-sectional study from September-November 2020. We used a self-administered survey tool which was distributed electronically to healthcare workers across the globe. The data were stored on an online database with password protected devices where survey responses were restricted to investigators exclusively.Data collected were: 1) Socio-demographic data (age, gender, marital status, ethnicity, religion, role in the healthcare, region of practice); 2) Psychological General Well-Being Index (PGWBI) questionnaire which contains 22 standardized items. This is a subjective assessment to score the degree of psychological well-being by focusing on 6 domains: depression; anxiety; positive-well-being; self-control; vitality and general health; 3) Subjective assessment from respondents of the main attributable factors causing psychological distress and suggested methods to help reduce the impact on mental health on health care workers.ResultMajority out of the 217 respondents were from a younger age group; females and married/domestic partnership, mainly from Western Pacific Region, South East Asian and the African Region. More than half the respondents were moderate-severely psychologically distressed and the three main attributable factors causing psychological distress were: fear of family/friends contracting COVID-19 followed by lack of PPE and discomfort caused by wearing PPE for long hours. Respondents suggested that the distress would be reduced if: more resources were provided in hospital; protocols and guidelines were implemented and counselling facilities with recreational activities were available to frontline workers.ConclusionThis study showed that the COVID-19 pandemic has affected the mental health of healthcare workers and more support or strategies need to come in place to protect frontline workers at the time of crises.

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Influence of COVID-19 on the Mental Health of Nurses dealing with COVID-19 Patients (A Study on Nurses within Karachi)

10.53350/pjmhs211551200 ◽

2021 ◽

Vol 15 (5) ◽

pp. 1200-1204

Author(s):

U. Amen ◽

Z. Rajwani ◽

U. Sumayya ◽

R. Haroon ◽

N. Mushtaq ◽

...

Keyword(s):

Mental Health ◽

Psychological Distress ◽

Preventive Intervention ◽

Cross Sectional Study ◽

Depression Anxiety Stress Scale ◽

Cross Sectional ◽

Moderate Depression ◽

Study Results ◽

The Impact ◽

Severe Anxiety

Background: Globally Corona virus (COVID-19) has become a huge challenge for all of the population. In South Asia, country Pakistan city Karachi the 1st case of this breakdown was identified on 26th February 2020 (Waris et al., 2020). This disease has developed psychological distress among all the population. COVID virus is one of the leading threats to all the healthcare organizations and due to increase rate of patients day by day, it has given enormous burden to all healthcare workers especially nurses the front line fighters who are always ready to give care towards the patient whom they encountered so it’s very crucial part to assess the impact of COVID -19 on the mental health of the nurses. Objective: The objective of the study is to identify the frequency level of stress, anxiety and depression among nurses while dealing with those patients who were admitted in various hospitals in Karachi for treatment of COVID-19. Method: A cross-sectional study was conducted from 20th November to 31st December 2020 from different hospitals in Karachi, Pakistan. Those Registered nurses who were assigned in isolation ward of Covid-19 were the part of the study. For data collection survey form was designed based on Depression Anxiety Stress scale (DASS-21) scale (Lovibond & Lovibond 1995). Results: The total mean score of depression among nurses was 50 (68%), Anxiety was 32 (43%) and stress was 34 (46%). 50 nurses suffered from moderate depression, 24 nurses reported from extremely severe anxiety and 50 nurses suffered from moderate stress level. From 74 participants 41(55.4%) were females and 33 (44.6%) were males. Furthermore, it shows that 25 (76%) males and 25 (61%) females suffered from moderate depression, 32 nurses 14 (42%) male and 18(43.90%) females reported from extremely severe anxiety. Conclusion: This pandemic is highly complex, contagious and vulnerable. The study results portrait that nurses working with COVID-19 patients have affected a lot of various psychological distress such as anxiety, stress, and depression. It is very vital for higher management to take major steps and take preventive intervention which would be beneficial towards their mental health in decreasing negative psychological outcomes, because they all are working under pressure environment. Key Words: Stress, Anxiety, Depression, Pandemic, Registered Nurse

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Self-reported psychological distress during the COVID-19 outbreak in Nepal: findings from an online survey

BMC Psychology ◽

10.1186/s40359-020-00497-z ◽

2020 ◽

Vol 8 (1) ◽

Author(s):

Kamal Gautam ◽

Ramesh P. Adhikari ◽

Aman Sen Gupta ◽

Rajan Kumar Shrestha ◽

Pitambar Koirala ◽

...

Keyword(s):

Mental Health ◽

Social Media ◽

Psychological Distress ◽

Online Survey ◽

Family Income ◽

Virus Disease ◽

Psychological Wellbeing ◽

The Past ◽

Psychological Impacts ◽

The Impact

Abstract Background A lower respiratory tract infection caused by novel coronavirus termed as Corona Virus Disease (COVID-19) was first identified in China and subsequently took the form of pandemic. Studies on disease outbreak in the past and recent COVID-19 outbreak have demonstrated increased psychological distress and adverse impacts on mental health and psychological wellbeing of people. However, the impact of COVID-19 on psychological wellbeing of people in Nepal hasn't been studied adequately. So, this paper aims to report the findings from a social media survey on psychological impacts of COVID-19 in Nepal. Methods Data were collected through social media from 2082 Nepalese respondents between 23rd April, 2020 and 3rd May, 2020. A total of 2014 respondents who were currently residing in Nepal were included in the analysis. Results The study suggested that half of the respondents suffered from at least one symptom of psychological distress whereas 32% suffered from two or more symptoms of psychological distress such as restlessness, fearfulness, anxiety and worry and sadness in the past 2 weeks preceding the survey date. The findings further suggested that respondents having lower family income, residing in rented room, and participants from province 2 were more likely to suffer from both single and multiple symptoms of psychological distress. Conclusion The study has shown high prevalence of psychological distress amongst the Nepalese respondents following COVID-19 outbreak. Appropriate mental health and psychosocial support response needs to be instituted to adequately respond to psychological impacts of the epidemic.

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