Functionality and Neurocognition in Patients With Bipolar Disorder After a Physical-Exercise Program (FINEXT-BD Study): Protocol of a Randomized Interventionist Program

An intensive physical exercise program could lead to a decrease in immune system function. Effects of long-term supplementation of bovine colostrum on the response of immune function on physical exercise test in athletes were examined. Twenty-seven elite female basketball players (age 16–19) were randomly assigned to either an experimental group or a control group. Eventually, n = 11 athletes completed intervention in the experimental group (3.2 g bovine colostrum orally twice a day for 24 weeks), while n = 9 athletes in the control group were given a placebo. Before the supplementation, after 3 and 6 months, subjects performed the physical exercise stress test. Before, just after, and 3 h after physical exercise testing, blood was drawn and immune system indicators were examined. Plasma interleukin (IL)-1alpha, IL-2, IL-10, IL-13, tumor necrosis factor (TNF) alpha, creatine kinase (CK MM), immunoglobulin G (IgG), insulin-like growth factor 1 (IGF1), and WBC, lymphocyte (LYM), monocyte (MON), and granulocyte (GRA) were measured. A statistically significant change in IL-10 in response to the exercise program during the supplementation period in both groups was observed (p = 0.01). However, the results of the rest of the comparisons were statistically insignificant (p > 0.05). Contrary to our initial hypothesis, there were no significant effects of bovine supplementation on the dynamics of immune system function indicators.

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POSITIVE study: physical exercise program in non-operable lung cancer patients undergoing palliative treatment

BMC Cancer ◽

10.1186/s12885-016-2561-1 ◽

2016 ◽

Vol 16 (1) ◽

Cited By ~ 16

Author(s):

Joachim Wiskemann ◽

Simone Hummler ◽

Christina Diepold ◽

Melanie Keil ◽

Ulrich Abel ◽

...

Keyword(s):

Lung Cancer ◽

Physical Exercise ◽

Cancer Patients ◽

Palliative Treatment ◽

Exercise Program ◽

Lung Cancer Patients ◽

Positive Study

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3D Kinematics and Decision Trees to Predict the Impact of a Physical Exercise Program on Knee Osteoarthritis Patients

Applied Sciences ◽

10.3390/app11020834 ◽

2021 ◽

Vol 11 (2) ◽

pp. 834

Author(s):

Marwa Mezghani ◽

Nicola Hagemeister ◽

Youssef Ouakrim ◽

Alix Cagnin ◽

Alexandre Fuentes ◽

...

Keyword(s):

Physical Exercise ◽

Knee Osteoarthritis ◽

Decision Trees ◽

Exercise Program ◽

Patient Specific ◽

Pain Level ◽

Knee Kinematic ◽

Kinematic Data ◽

3D Kinematics ◽

The Impact

Measuring knee biomechanics provides valuable clinical information for defining patient-specific treatment options, including patient-oriented physical exercise programs. It can be done by a knee kinesiography test measuring the three-dimensional rotation angles (3D kinematics) during walking, thus providing objective knowledge about knee function in dynamic and weight-bearing conditions. The purpose of this study was to assess whether 3D kinematics can be efficiently used to predict the impact of a physical exercise program on the condition of knee osteoarthritis (OA) patients. The prediction was based on 3D knee kinematic data, namely flexion/extension, adduction/abduction and external/internal rotation angles collected during a treadmill walking session at baseline. These measurements are quantifiable information suitable to develop automatic and objective methods for personalized computer-aided treatment systems. The dataset included 221 patients who followed a personalized therapeutic physical exercise program for 6 months and were then assigned to one of two classes, Improved condition (I) and not-Improved condition (nI). A 10% improvement in pain was needed at the 6-month follow-up compared to baseline to be in the improved group. The developed model was able to predict I and nI with 84.4% accuracy for men and 75.5% for women using a decision tree classifier trained with 3D knee kinematic data taken at baseline and a 10-fold validation procedure. The models showed that men with an impaired control of their varus thrust and a higher pain level at baseline, and women with a greater amplitude of internal tibia rotation were more likely to report improvements in their pain level after 6 months of exercises. Results support the effectiveness of decision trees and the relevance of 3D kinematic data to objectively predict knee OA patients’ response to a treatment consisting of a physical exercise program.

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Are palliative cancer patients willing and able to participate in a physical exercise program?

Palliative & Supportive Care ◽

10.1017/s1478951505050443 ◽

2005 ◽

Vol 3 (4) ◽

pp. 281-287 ◽

Cited By ~ 49

Author(s):

LINE M. OLDERVOLL ◽

JON H. LOGE ◽

HANNE PALTIEL ◽

MAY B. ASP ◽

UNNI VIDVEI ◽

...

Keyword(s):

Palliative Care ◽

Physical Exercise ◽

Training Program ◽

Cancer Patients ◽

Physical Training ◽

Exercise Program ◽

Group Exercise ◽

Medical Problems ◽

Incurable Cancer ◽

The Individual

Objective: The primary aim of the present article was to identify palliative care patient populations who are willing to participate in and able to complete a group exercise/physical training program designed specifically for the individual patient.Method: We conducted a prospective phase II intervention study examining the willingness and ability of palliative care cancer patients to participate in a group exercise physical training program. Patients who were diagnosed with incurable cancer and had a life expectancy of less than 1 year at two outpatient clinics were invited to participate in an exercise program in the hospitals. The groups met twice a week over a 6-week period.Results: One hundred one consecutive patients were asked for inclusion. Sixty-three patients agreed to participate. Sixteen (25%) of the 63 patients dropped out after consent was given, but before the program started due to medical problems, social reasons, or death. Thus, 47 patients started the exercise program. Thirteen patients withdrew during the program due to sudden death, medical problems, or social reasons. The most frequent reasons for withdrawal were increased pain or other symptoms. Thirty-four patients completed the exercise program.Significance of results: A high proportion of incurable cancer patients were willing to participate (63%) in a structured exercise program. The attrition rate was high, but despite being severely ill, 54% of the patients completed the exercise period. This shows that a physical exercise program tailored to the individual patient is feasible in this population.

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