scholarly journals Early Life Experiences Moderate the Relationship Between Genetic Risk of Autism and Current and Lifetime Mental Health

2021 ◽  
Vol 12 ◽  
Author(s):  
Su Hyun Shin ◽  
Cheryl Wright ◽  
Susan Johnston
Keyword(s):  
Mental Health ◽  
Older Adults ◽  
Genetic Risk ◽  
Early Life ◽  
Life Experiences ◽  
Random Effect ◽  
Epidemiologic Studies ◽  
History Of ◽  
The Relationship ◽  
Psychiatric Problems

Although individuals with autism are at greater risk of mental health challenges than others, we know little about the relationship between the mental health of older adults (50+) and autism because they are less likely to be diagnosed. Identifying the risk and protective factors that are associated with mental health can increase educational awareness, inform clinical practice, and provide information to help diagnose and treat older adults with autism. This study used longitudinal panel data of the 2008–2016 waves of the Health and Retirement Study. It estimated individual random-effect models by interacting a genetic propensity toward autism and early life experiences to test whether the latter has a moderating effect on the relationships between genetics and the Center for Epidemiologic Studies Depression (CES-D) score, self-reported depression, and history of psychiatric problems. Results suggest that individuals with a higher genetic propensity for autism are less likely to develop psychiatric problems if they report a positive maternal relationship early in life. Further, a combined effect of police encounters early in life and genetic risk for autism is associated with higher CES-D scores, increased odds of self-reported depression, and a history of psychiatric problems. Clinical applications of these findings include the need to establish and support high-quality relationships by addressing both child and caregiver needs. Further, these findings support the need to design and implement proactive interventions to teach police and autistic individuals how to successfully navigate these encounters.

Roles of Psychological Distress and Social Support in the Relationship Between Childhood Maltreatment and Perceived Needs for Mental Health Care

2021 ◽  
pp. 088626052110063
Author(s):  
Tingting Gao ◽  
Songli Mei ◽  
Muzi Li ◽  
Carl D’ Arcy ◽  
Xiangfei Meng
Keyword(s):  
Mental Health ◽  
Social Support ◽  
Health Care ◽  
Psychological Distress ◽  
Mental Health Care ◽  
Childhood Maltreatment ◽  
Perceived Needs ◽  
Perceived Need ◽  
History Of ◽  
The Relationship

Childhood maltreatment is a major public health issue worldwide. It increases a range of health-risk behaviors, psychological and physical problems, which are associated with an increased need for mental health services in adulthood. Identification of mediating factors in the relationship between maltreatment and seeking mental health care may help attenuate the negative consequences of childhood maltreatment and promote more appropriate treatment. This study aims to examine whether the relationship between childhood maltreatment and perceived need for mental health care is mediated by psychological distress and/or moderated by social support. Data from the Canadian Community Health Survey-Mental Health 2012 are analyzed. A total of 8,993 participants, who had complete information on childhood maltreatment and diagnoses of mental disorders or psychological distress, are included in this study. Structural equation modeling and the PROCESS macro were used to identify relationships among childhood maltreatment, perceived needs for mental health care, and psychological distress. Hierarchical linear regression was then used to verify the moderated mediation model. We found that psychological distress partially mediated the effect of childhood maltreatment on perceived needs for mental health care in adulthood. Social support played an important role in terms of moderating the relationship between maltreatment and perceived needs for care. For those with a history of childhood maltreatment, those who perceived a low level of social support were more likely to have higher levels of psychological distress and perceived need for mental health care. This is the first study to identify the separate and combined roles of psychological distress and social support in the relationship between childhood maltreatment and perceived need for mental health care. Selective prevention strategies should focus on social support to improve mental health services among people with a history of childhood maltreatment.

scholarly journals Attitude toward Aging Mediates the Relationship between Personality and Mental Health in Older Adults

Healthcare ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 594
Author(s):  
Teshome Sirak Bedaso ◽  
Buxin Han
Keyword(s):  
Mental Health ◽  
Older Adults ◽  
Life Satisfaction ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Personality Factors ◽  
Health Issues ◽  
Cross Sectional ◽  
Potential Mediator ◽  
The Relationship

This study aimed to examine attitude toward aging as a potential mediator of the relationship between personality factors and mental health in terms of depression and life satisfaction among older adults. A cross-sectional study was conducted with 438 Ethiopian elderly individuals aged 60 to 69. The results of the regression-based path analysis showed that after adjusting for demographic data, the relationship between agreeableness and depression in older adults was partially mediated by attitude toward aging. Likewise, attitude toward physical change due to aging and psychological growth subscales jointly mediated the correlation between neuroticism and depression. However, a significant direct path between neuroticism and depression persisted. On the contrary, openness had no significant direct association with depression apart from an indirect through psychosocial loss. The link between life satisfaction and agreeableness as well as openness to experience were partially mediated by psychosocial loss. Therefore, a person’s attitude toward aging and personality characteristics should be taken into consideration while designing interventions for managing mental health issues among older adults.

scholarly journals Gene regulation contributes to explain the impact of early life socioeconomic disadvantage on adult inflammatory levels in two cohort studies

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Cristian Carmeli ◽  
Zoltán Kutalik ◽  
Pashupati P. Mishra ◽  
Eleonora Porcu ◽  
Cyrille Delpierre ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Gene Regulation ◽  
Cohort Studies ◽  
Early Life ◽  
Life Experiences ◽  
Socioeconomic Disadvantage ◽  
Mediating Role ◽  
The Impact ◽  
The Relationship

AbstractIndividuals experiencing socioeconomic disadvantage in childhood have a higher rate of inflammation-related diseases decades later. Little is known about the mechanisms linking early life experiences to the functioning of the immune system in adulthood. To address this, we explore the relationship across social-to-biological layers of early life social exposures on levels of adulthood inflammation and the mediating role of gene regulatory mechanisms, epigenetic and transcriptomic profiling from blood, in 2,329 individuals from two European cohort studies. Consistently across both studies, we find transcriptional activity explains a substantive proportion (78% and 26%) of the estimated effect of early life disadvantaged social exposures on levels of adulthood inflammation. Furthermore, we show that mechanisms other than cis DNA methylation may regulate those transcriptional fingerprints. These results further our understanding of social-to-biological transitions by pinpointing the role of gene regulation that cannot fully be explained by differential cis DNA methylation.

Relationship Between Mental Health, Resilience, and Physical Activity in Older Adults: A 2-Year Longitudinal Study

2021 ◽  
pp. 1-9
Author(s):  
Maria Priscila Wermelinger Ávila ◽  
Jimilly Caputo Corrêa ◽  
Alessandra Lamas Granero Lucchetti ◽  
Giancarlo Lucchetti
Keyword(s):  
Mental Health ◽  
Physical Activity ◽  
Older Adults ◽  
Regression Models ◽  
Linear Regression Models ◽  
Physically Active ◽  
Effective Interventions ◽  
Self Sufficiency ◽  
The Relationship

The aim of this study was to longitudinally investigate the association between resilience and mental health in older adults and to determine the influence of physical activity on this relationship. A total of 291 older adults were included in a 2-year follow-up study. Adjusted linear regression models evaluated the association between resilience at baseline and mental health after 2 years in sufficiently and insufficiently physically active older adults. A negative correlation was found between resilience at baseline and depression, anxiety, and stress after 2 years for the overall sample. This association changed after stratifying the group. Sufficiently physically active individuals made greater use of the resilience components “Self-Sufficiency” and “Perseverance,” whereas insufficiently physically active individuals made greater use of “Meaning of Life” and “Existential Singularity.” Physical activity can influence the relationship between resilience and mental health. These results can help guide the devising of more effective interventions for this age group.

scholarly journals The differential calibration of the HPA axis as a function of trauma versus adversity: A systematic review and p-curve meta-analyses

2021 ◽  
Author(s):  
Niki H. Kamkar ◽  
Cassandra J Lowe ◽  
J. Bruce Morton
Keyword(s):  
Hpa Axis ◽  
Early Life ◽  
Life Experiences ◽  
Curve Analysis ◽  
Early Life Adversity ◽  
Cortisol Reactivity ◽  
Evidential Value ◽  
Dsm 5 ◽  
Meta Analyses ◽  
The Relationship

Although there is an abundance of evidence linking the function of the hypothalamic-pituitary-adrenal (HPA) axis to adverse early-life experiences, the precise nature of the association remains unclear. Some evidence suggests early-life adversity leads to cortisol hyper-reactivity, while other evidence suggests adversity leads to cortisol hypo-reactivity. Here, we distinguish between trauma and adversity, and use p-curves to interrogate the conflicting literature. In Study 1, trauma was operationalized according to DSM-5 criteria; the p-curve analysis included 68 articles and revealed that the literature reporting associations between trauma and blunted cortisol reactivity contains evidential value. Study 2 examined the relationship between adversity and cortisol reactivity. Thirty articles were included in the analysis, and p-curve demonstrated that adversity is related to heightened cortisol reactivity. These results support an inverted U-shaped function relating severity of adversity and cortisol reactivity, and underscore the importance of distinguishing between “trauma” and “adversity”.

Religiosity and Adaptation in the Oldest-Old

1992 ◽  
Vol 34 (1) ◽  
pp. 47-56 ◽  
Author(s):  
Bradley C. Courtenay ◽  
Leonard W. Poon ◽  
Peter Martin ◽  
Gloria M. Clayton ◽  
Mary Ann Johnson
Keyword(s):  
Mental Health ◽  
Older Adults ◽  
Life Satisfaction ◽  
Religious Coping ◽  
Significant Relationship ◽  
Oldest Old ◽  
Coping Mechanisms ◽  
Physical And Mental Health ◽  
And Coping ◽  
The Relationship

Previous research has yielded mixed results with respect to the relationship between religiosity and adaptation in older adults. Most studies show that religiosity is stable over the life span, but that religiosity may or may not be related to such factors as physical and mental health, life satisfaction, and coping. This study adds to earlier investigations by including centenarians among the sample. The preliminary results of this research project support earlier findings that religiosity does not change significantly as one ages, although there is a trend in the results that suggests otherwise. The results also indicate a significant relationship between religiosity and physical health but no significant relationship between religiosity and mental health and life satisfaction. Religiosity and coping are strongly related, and there is the suggestion that religious coping mechanisms might be more important in the oldest-old.

scholarly journals The Impact of Distal Influences and Proximal Resources on the Mental Health of African American Older Adults: Findings From the Georgia Centenarian Study

2020 ◽  
Vol 4 (5) ◽  
Author(s):  
Meneka C Johnson Nicholson ◽  
Peter Martin ◽  
Megan Gilligan ◽  
Carolyn E Cutrona ◽  
Daniel W Russell ◽  
...  
Keyword(s):  
Mental Health ◽  
Older Adults ◽  
African American ◽  
Health Outcomes ◽  
Early Life ◽  
Well Being ◽  
Mental Health Outcomes ◽  
Financial Resources ◽  
The Impact ◽  
African American Older Adults

Abstract Background and Objectives Over the years, a large amount of research has been devoted to the investigation of factors that led to mental health outcomes in older adults. For African American older adults, their lived experiences place them at high risk for mental health problems. The purpose of this study was to examine the impact of early life influences (i.e., education, childhood life events, and childhood financial well-being) and present psychosocial resources (i.e., individual, financial, and social) on current mental health outcomes in a sample of African American older adults in their 60s, 80s, and 100s. Research Design and Methods Using data from the Georgia Centenarian Study, 125 participants were interviewed about their mental health, resources, and early life influences. Results A structural equation model was tested and resulted in a good fit. Results indicated that the more social resources African American older adults had available, the lower the number of depressive symptoms they reported. African Americans with higher levels of financial well-being during childhood reported higher self-rated mental health. Older adults had higher levels of financial resources. Level of education showed a positive relationship with financial resources. Indirect effects of distal influences on health outcomes via current resources were not found. Discussion and Implications The findings are of direct practical relevance and can be used to more readily identify older African Americans who may be susceptible to poorer mental health outcomes based upon the impact of their unique distal and proximal psychosocial resources.

scholarly journals The COVID-19 Pandemic and Psychosocial Outcomes across Age through the Stress and Coping Framework

2020 ◽  
Author(s):  
Jillian Minahan ◽  
Francesca Falzarano ◽  
Neshat Yazdani ◽  
Karen L Siedlecki
Keyword(s):  
Mental Health ◽  
Social Support ◽  
Older Adults ◽  
Coping Style ◽  
Psychosocial Outcomes ◽  
Well Being ◽  
Stress And Coping ◽  
Related Stress ◽  
And Coping ◽  
The Relationship

Abstract Background and Objectives The emergence of the Coronavirus Disease 2019 (COVID-19) and the measures implemented to curb its spread may have deleterious effects on mental health. Older adults may be at increased risk for adverse psychosocial outcomes since opportunities to remain socially connected have diminished. Research is needed to better understand the impact of pandemic-related stress on mental health. The purpose of this study is three-fold: 1) to examine the influences of COVID-19 pandemic-related stress on depression, anxiety, and loneliness, 2) to assess the mediating role of coping style and social support, and 3) to investigate whether these relationships vary across age. Research Design and Methods Participants (N = 1,318) aged 18-92 years completed an online survey assessing pandemic-related stress, mental health, social support, coping, and their experiences with social distancing, during the initial implementation of social distancing measures in the United States. Results Social support and coping style were found to relate to psychosocial outcomes. Avoidant coping was the strongest mediator of the relationship between pandemic-related stress and psychosocial outcomes, particularly depression. Avoidant coping more strongly mediated the relationship between stress and depression in younger adults compared to older adults. Discussion and Implications Results were consistent with the stress and coping framework and recent work highlighting older adults’ resilience during the COVID-19 pandemic. Findings highlight the associations between positive coping behaviors and psychosocial well-being and indicate that older adults may use unique adaptive mechanisms to preserve well-being during the COVID-19 pandemic.

Sign in / Sign up

Export Citation Format

Share Document