scholarly journals Gene Therapy Knowledge and Attitude Among Healthcare Professionals: A Cross-Sectional Study

2021 ◽  
Vol 9 ◽  
Author(s):  
Maha M. AlRasheed ◽  
Hatoon AlAli ◽  
Abdulrahman F. Alsuwaid ◽  
Suhail Khalaf ◽  
Sondus I. Ata ◽  
...  

This study aimed to assess healthcare professionals' knowledge, attitudes, and concerns toward gene therapy in Saudi Arabia. We conducted an online cross-sectional survey via convenience sampling during the period from December 2018 to March 2019. A total of 419 (358 pharmacists and 61 physicians) responded to our questionnaire. Three hundred and nine (73.7%) were male, and the mean (±SD) age of 32.0 ± 7.7 years. The mean knowledge scores of all participants, pharmacists, and physicians were 3.8 ± 1.9, 3.8 ± 1.9, and 3.7 ± 1.9, respectively (P = 0.73). Higher knowledge score was associated with younger age (Coefficient: −0.03; P = 0.02), male (Coefficient: 0.57; P = 0.01), master's degree (Coefficient: 0.93; P = 0.003) and Ph.D. holders (Coefficient: 1.10; P = 0.01), and participants graduated from Canada (Coefficient: 2.10; P = 0.01).Moreover, about half of the respondents (55%) were concerned about gene therapy, and genetics training at college was considered the best gene therapy education method by 69.4%. Attitude score was not significantly associated with the profession (P = 0.88) but positively correlated with the knowledge score (rho= 0.4; P < 0.001). In conclusion, pharmacists and physicians showed limited knowledge with a positive attitude toward gene therapy. Therefore, educational programs on gene therapy need to be considered, focusing primarily on the safety, and social acceptance of such new therapeutic management.

Healthcare ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1600
Author(s):  
Samantha Yun-Kai Poon ◽  
Jason C. Hsu ◽  
Yu Ko ◽  
Shao-Chin Chiang

Despite the first approval of biosimilars’ in 2010, biosimilar products usage has remained low in Taiwan. This cross-sectional survey study assessed healthcare professionals’ (HCPs)—hospital pharmacists, oncologists, and rheumatologists—knowledge, and attitudes toward biosimilars. More precisely, their knowledge and attitude towards biosimilars’ current usage and regulations in Taiwan were analyzed. The mean ± standard deviation knowledge score was 2.56 ± 0.86 out of 4 (n = 395), and a difference in knowledge score was determined according to the hospital types (p = 0.004). Rheumatologists possessed significantly higher confidence in their knowledge of biosimilars than other HCPs (p = 0.001). Pharmacists showed the highest acceptance—and rheumatologists the least—for switching patients from reference drugs to biosimilars (p = 0.02). Hospital type was associated with the respondent’s confidence in their knowledge (p = 0.04) and the preference for distinguishable naming of biosimilars (p = 0.007). Their knowledge scores were associated with their confidence in the efficacy and safety of biosimilars (p = 0.02). The study found that the current level of biosimilar knowledge of HCPs in Taiwan is low. The higher the knowledge score, the greater the confidence in biosimilars and the familiarity with relevant regulations.


Author(s):  
Suresh Kumar ◽  
Kingston Rajiah ◽  
Sajesh Kalkandi Veettil ◽  
Ng Sze Wei

Abstract: The objectives of this study were to determine the knowledge and attitude of adult Malaysians about Traditional Chinese Medicine (TCM), to understand the variation in the knowledge and attitude toward TCM among different demographic groups of adult Malaysian population and to determine the pattern of TCM use among adult Malaysians.: This study was a descriptive, cross-sectional survey using the convenience sampling method. A total of 400 adult Malaysians were recruited for this study. An interview-administered questionnaire was used. Descriptive statistics Mann-Whitney U Test and Kruskal–Wallis H test were used to analyze the data. The reliability of survey data in this study may affect since closed-ended questions are used.: The more commonly utilized therapy was herbal medicine (n=192, 82.1%), acupuncture (n=79, 33.8%) and oriental massage (n=58, 24.8%). The mean knowledge score and mean attitude score for the respondents were 5.00±1.71 and 7.17±2.10 respectively. There was a significant difference in the mean knowledge score between genders, among TCM users and non-TCM users, people of different education levels and ethnicity.: There were more TCM users than non-TCM users and the use of TCM was higher in females than males. The most popularly used TCM modalities were herbal medicines and acupuncture. Gender, education, ethnicity and use of TCM had a significant effect on adults’ knowledge toward TCM.


Author(s):  
Satendra Kumar Verma ◽  
D. Sunil Kumar ◽  
Rufia Shaistha Khanum ◽  
Chandan N. ◽  
M. R. Narayanmurthy

Background: COVID-19 is a Public health emergency of international concern which has affected over 213 countries infecting millions across the globe and also affected the economy worldwide. This study was conducted in Healthcare Workers as they are the frontline warriors in fighting this pandemic and their knowledge, attitude and practices towards the disease are valuable.Methods: Online cross sectional study was conducted on Healthcare Workers. A self-administered Google form was used to collect the data through social media. Data was analyzed using MS Excel. P<0.05 was considered statistically significant obtained using SPSS version 22.Results: The mean age among the participants was 30.7±9.9 years. Majority were in the age group of 20-30 years (60.9%), followed by 31-40 years (18.9%), 41.-50 years (9.1%) and >50 years (5.4%). 46.3% of the participants were females and 53.0% were males. 37.1% were doctors, 14.0% are nurses and 46.9% are paramedical staff. In the present study, Mean knowledge score is 5.86±1.32, mean attitude score is 6.48±0.93 and the mean practice score is 4.60±0.79, thus 95.7% of the participants have good knowledge and attitude, where as 90.3% have good practices towards COVID-19.Conclusions: The HCWs of Karnataka have good knowledge, positive attitude and good practices. To further improve their preparedness and response towards infectious diseases and pandemics mandatory training programs can be introduced, as such programs enhances knowledge and boosts confidence among HCWs which is very crucial in medical as well as public health emergencies.


Author(s):  
M.K. Sreelakshmi ◽  
Suneesh Kuruvilla ◽  
Ramanarayanan Subramaniam ◽  
Pooja Latti ◽  
Ramanarayanan Venkitachalam

Abstract Background: Chengannur, a town in the south Indian state of Kerala, was 1 of the worst affected towns during the floods of 2018. Post-flood, Kerala state was under the threat of many infectious diseases including leptospirosis, but did not report any leptospirosis infections. Objectives: This study was conducted with the following objectives: (1) Assess the knowledge, attitude and practices regarding the prevention of leptospirosis among the flood affected population and Accredited Social Health Activists (ASHAs) of Chengannur; and (2) Analyze the factors responsible for and contributing to leptospirosis control in the area post flood. Methodology: A cross-sectional questionnaire based observational study was conducted among 2 groups: the flood affected population, and ASHA. The questionnaire was divided into 3 parts. Part A contained the socio-demographic information. Part B contained questions on assessment of knowledge, attitude, and practices regarding the prevention, and control of leptospirosis. Part C was only for the ASHA involved. Results: The final sample size was 331 (244 from the general population and 87 ASHAs). With respect to knowledge, attitude, and practice, the responses were dichotomized into correct and wrong responses. The mean knowledge score was 9.01 ± 1.08 (maximum score of 10), mean attitude score was of 3.61 ± 0.55 (maximum score of 4) and the mean practice score was 4.12 ± 1.05 (maximum score of 5). Conclusion: Knowledge and attitude scores did not significantly differ between the general population and ASHA, but the practice score showed a higher score among the ASHA, all of which could have probably contributed to the prevention of a leptospirosis outbreak in the region.


2016 ◽  
Vol 2016 ◽  
pp. 1-15 ◽  
Author(s):  
Eman Al-Hashemi ◽  
Abdullatif Ashkanani ◽  
Haneen Al-Qattan ◽  
Asmaa Mahmoud ◽  
Majd Al-Kabbani ◽  
...  

Background and Objectives. Attitudes toward students with epilepsy and epilepsy-related knowledge of teachers are crucial for child’s safety in the school. The aim of this study was to evaluate teachers’ knowledge and attitudes toward epilepsy.Methods. This cross-sectional study included 824 teachers from 24 randomly selected middle and high schools. Scale of Attitudes Toward Persons with Epilepsy (ATPE) was modified to assess teachers’ knowledge about epilepsy and attitudes toward students with epilepsy.Results. Median knowledge score about epilepsy was 5 (out of 13), while median attitude score was 10 (out of 15). Both knowledge and attitude median scores were significantly higher in senior teachers with longer teaching experience and in respondents who dealt with a person with epilepsy. There was significant association between knowledge score and attitude score (p<0.01). Logistic regression showed that significant variables, independently associated with poor knowledge after adjusting for possible confounders, were not having a family member with epilepsy (p=0.009), unawareness of life circumstances of persons with epilepsy (p=0.048), and a poor attitude score (p<0.001).Conclusion. School teachers in Kuwait have relatively poor knowledge about epilepsy but have positive attitudes toward students with epilepsy. A number of historical and stigmatizing ideas about epilepsy still exist. It is recommended to provide teachers with information about handling seizures in the educational setting through development and implementation of epilepsy education programs.


Author(s):  
Ghaida Aziz, Ghaida jabri, Ghaida Al-Ahmadi, Mona Ehab, Marw

Breast feeding (BF) is known to have many advantages but our Arab region has a pattern similar to western countries; where exclusive breastfeeding less than 35%. Knowledge given to women during her antenatal visits plays an important influential role in her attitude and practice of BF later on.  Objective: To explore knowledge and attitude of female medical students at Taibah University about breastfeeding.  Methods: A Cross sectional study was carried out from October to November 2012. It included female medical students. Stratified sampling allocation technique was used; with a total sample of 149 students. A specialty designed self-administrated questionnaire in Arabic form was used. It included socio-demographic data, obstetric history, data about the knowledge and attitude of female medical students towards breastfeeding value and guidelines. Mean percent knowledge score for value of BF, mean percent score for BF guidelines and mean percent score for attitude were calculated. Appropriate statistical tests for qualitative and quantitative data were used accordingly. Results: Majority (91.9%) (of the studied sample) was never married and 37.6% got their knowledge about BF via books. Regarding ever married women, 58.3% only were gravid (mean =2.2±1.94). Only 25.0% were family planning users; 66.7% of them used hormonal contraceptives. Only 20% breast fed their infants with a mean duration for exclusive BF of 3.8 ± 2.87 months and mean age of weaning of 2.3 ±0.63 months. The mean knowledge percent score for guidelines of BF was 64.7±8.45. The mean attitude percent score for concepts related to BF was 76.9±7.91. Conclusion: Media and internet have minor roles in getting knowledge about BF. The mean knowledge score about advantages of BF, guidelines of BF and attitude towards BF of all female medical students; especially academic years were unsatisfactory.


Author(s):  
Pratibha Srivastava

Today's Children will be tomorrow's responsible citizen of the country. Entertainment is an essential part of life, by this we feel tension free, relaxed, energetic and having a positive attitude towards life. Games plays an important role for the all round development of the children's personality especially outdoor games but Now a days children are adopting habits of playing indoor games and also entertaining themselves by using various electronic devices as we know one of them is television. There are various programmes such as various kids’ channels, cartoon shows, video games etc. being watched by the children. Directly or indirectly these programs affect behaviour of the children in positive and negative ways. That’s why it is needed that parents should have a look for types of programmes seen by children, how long a child is watching a program, how it is affecting child habits/ behaviour etc. Later on, these negative impacts will create health issues/behaviour problems such as obesity, aggressive behaviour, lack of concentration etc. Child who watch television for 10 hours or more per week are less skilled at reading and are less successful in school as compared to children who watch television for less than 10 hours per week. The American academy of paediatrics makes the following recommendations regarding television viewing should not exceed one to two hours of quality programming daily and children younger than two years old should not watch television.1 That is why researchers took this topic to highlight the attitude and knowledge of parents about the impact of television on their Children's behaviour. A co-relational study conducted to assess parental knowledge and attitude regarding the impact of television on children in selected area at Kanpur (U.P). A descriptive cross-sectional survey approach was used, sample size was 100 parents selected by convenient sampling for this study. Self-structured knowledge questionnaire was used to assess the knowledge of parents, and attitude of parents was assessed by Likert scale. The study shows that among 100 parents 8% of them had poor knowledge, 36% average knowledge, 50% good knowledge, 6% very good knowledge about impact of television on children. The study shown the positive attitude 84%, negative attitude 16% on impact of television on children. The correlation value shows that positive correlation between knowledge and attitude score of parents. There was no significant association between knowledge score with their demographic variables and significant association seen between attitude score with types of family, educational status of parents, income of parents and number of children. There was no significant association between attitude score with age of parents and religion. KEYWORDS: Impact, Television, Attitude, Parental Knowledge,


2020 ◽  
Vol 8 (2) ◽  
pp. 18-24
Author(s):  
Dilli Bahadur Pun ◽  
Bobby Thapa ◽  
Prashanna Shrestha ◽  
Sonam Chaudhary ◽  
Nashib Pandey ◽  
...  

Background and Objectives: Survival after cardiopulmonary arrest depends on early and effective cardiopulmonary resuscitation (CPR). Demand for courses of basic life support (BLS)/CPR is increasing worldwide. Till date, there have been little reports regarding CPR knowledge and attitude among the Nepalese dental health personnel. This study aimed to assess the knowledge and attitude towards CPR among undergraduate dental students, interns and postgraduate residents studying at Kantipur Dental College and Teaching Hospital (KDCH), Kathmandu, Nepal. Material and Methods: A descriptive cross-sectional study was conducted among 243 dental students studying at KDCH. Data was collected through a self -administered semi-structured questionnaire. Collected data was organized, recorded, coded and then analyzed using Statistical Package of Social Science (SPSS) version 16. Descriptive statistics was used to compute mean, percentile, standard deviation and one way ANOVA test was done to compare the mean knowledge score between different academic levels of the students at 95% level of significance. Results: The mean knowledge and attitude score towards CPR among the dental students was 8.05±2.85 and 4.63±0.51 respectively. Out of total students, only few (5.8%) had adequate knowledge whereas all (100%) had a positive attitude towards CPR. The mean score for the pre-clinical students (7.26 ±2.38) was significantly (p=0.001) lower than clinical students (8.44 ±3.23), interns and residents (8.85 ±2.54). Conclusion: The present study showed inadequate knowledge regarding CPR among dental students of different academic levels but they have a positive attitude towards it. The integration of CPR in the early year of the curriculum along with regular training of CPR in succeeding years will enhance their knowledge.


2021 ◽  
Vol 28 (03) ◽  
pp. 399-406
Author(s):  
Nazish Waheed ◽  
Brekhna Jamil ◽  
Robina Usman ◽  
Humera Waqar

Objective: This study was conducted to evaluate the knowledge and attitude of undergraduate medical students toward research. Study Design: Cross sectional study. Setting: Private Medical Colleges of Khyber Pakhtunkhwa. Period: November 2018 to July 2019. Material & Methods: A total of 938 final year medical students participated in the study. A validated self administered questionnaire was used for the collection of data. The student’s perception was assessed through questionnaire based on 5-point Likert scale. For the assessment of knowledge MCQs were marked as 1 in case of correct answer and 0 in case of incorrect answer. Results: Out of 1300 students, 938 returned the questionnaire resulting in a 74% response rate. 481(51%) participants were male and 457(49%) were females. The participants had a mean knowledge score of 6.103 out of a total of 15 questions and mean attitude score of 76.29. Conclusion: This study concludes a low knowledge score coupled with a positive attitude of doing research. More attention must be placed on these parameters in the curriculum to improve student knowledge in health research.


Author(s):  
Gyanendra Kumar ◽  
Aditi Garg ◽  
Jatinder Kaur Dhillon ◽  
Arshad Eranhikkal ◽  
Manjakandi Smitha

Background: Medicines play a main role in the process of human development. The rational utilization of medicines can decrease morbidity and mortality as well as improve quality of life. In an era of steeply rising health care expenses, generic medicines provide a less expensive alternative to branded medicines. Use of generic drugs can contribute to substantial savings in medicines expenditure and the issue of access and affordability is thus addressed.Methods: A sample of 500 patients selected from out patient department was randomly selected. A self-instructed questionnaire was used for the study for the duration of 1 month. Data was analyzed using IBM SPSS statistics Version 20 New York, United States. Summary statistics were expressed using mean and standard deviation (SD) for numerical variables (median and interquartile ranges [IQRs] when skewed) and counts and percentages for categorical variables.Results: Participants reported with 17.23% knowledge score, 40.65% attitude score, and 7.96% attitude score.Conclusions: In the study it was found that there is significant correlation between knowledge and attitude whereas no correlation was found between knowledge and practice regarding usage of generic drugs.


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