scholarly journals Fluorescent Chemosensors for Ion and Molecule Recognition: The Next Chapter

2021 ◽  
Vol 2 ◽  
Author(s):  
Kai-Cheng Yan ◽  
Axel Steinbrueck ◽  
Adam C. Sedgwick ◽  
Tony D. James

Over the past 30 years fluorescent chemosensors have evolved to incorporate many optical-based modalities and strategies. In this perspective we seek to highlight the current state of the art as well as provide our viewpoint on the most significant future challenges remaining in the area. To underscore current trends in the field and to facilitate understanding of the area, we provide the reader with appropriate contemporary examples. We then conclude with our thoughts on the most probable directions that chemosensor development will take in the not-too-distant future.

Author(s):  
Satyandra K. Gupta ◽  
Diganta Das ◽  
William C. Regli ◽  
Dana S. Nau

Abstract In the marketplace of the 21st century, there is no place for traditional over-the-wall communication between design and manufacturing. In order to “design it right the first time,” designers must ensure that their products are both functional and easy to manufacture. Software tools have had some successes in reducing the barriers between design and manufacturing. Manufacturability analysis systems are emerging as one such tool — enabling identification of potential manufacturing problems during the design phase and providing suggestions to designers on how to eliminate them. In this paper, we survey current state of the art in automated manufacturability analysis. We describe the existing approaches to automated manufacturability analysis and overview representative systems based on their application domain. Finally, we attempt to expose some of the existing research challenges and future directions.


2016 ◽  
Vol 371 (1688) ◽  
pp. 20150106 ◽  
Author(s):  
Margaret M. McCarthy

Studies of sex differences in the brain range from reductionistic cell and molecular analyses in animal models to functional imaging in awake human subjects, with many other levels in between. Interpretations and conclusions about the importance of particular differences often vary with differing levels of analyses and can lead to discord and dissent. In the past two decades, the range of neurobiological, psychological and psychiatric endpoints found to differ between males and females has expanded beyond reproduction into every aspect of the healthy and diseased brain, and thereby demands our attention. A greater understanding of all aspects of neural functioning will only be achieved by incorporating sex as a biological variable. The goal of this review is to highlight the current state of the art of the discipline of sex differences research with an emphasis on the brain and to contextualize the articles appearing in the accompanying special issue.


2019 ◽  
Vol 217 (3) ◽  
pp. 521-523 ◽  
Author(s):  
Anthony S. David

Academic interest in the concept of insight in psychosis has increased markedly over the past 30 years, prompting this selective appraisal of the current state of the art. Considerable progress has been made in terms of measurement and confirming a number of clinical associations. More recently, the relationship between insight and involuntary treatment has been scrutinised more closely alongside the link between decision-making capacity and insight. Advances in the clinical and cognitive neurosciences have influenced conceptual development, particularly the field of ‘metacognition’. New therapies, including those that are psychologically and neurophysiologically based, are being tested as ways to enhance insight.


2001 ◽  
Vol 5 (1_suppl) ◽  
pp. 3-21 ◽  
Author(s):  
Patrik N. Juslin ◽  
Marcel R. Zentner

The study of musical emotion is currently witnessing a renaissance. However, the literature on music and emotion still presents a confusing picture. The conceptual terrain is still being mapped, and considerable refinement is still needed in how we study music and emotion. With all the research currently devoted to this subject, it is all the more important that we have a good grasp of the current state of the art, so that we do not invent the wheel twice. With this aim in mind, the present authors organized a symposium at the Sixth International Conference on Music Perception and Cognition in Keele, UK, August, 2000. The intention was to bring together several researchers who have made theoretical and empirical contributions to the field in order to display “Current trends in the study of music and emotion”. This special issue presents extended and revised papers from that symposium, including a number of additional contributions. In this paper, we provide an introduction. We discuss the historical background, highlight the primary issues as they relate to the contents of the others contributions, and finally consider the gap that exists between art and science.


2015 ◽  
Vol 62 (5) ◽  
pp. 3021-3032 ◽  
Author(s):  
Sheldon S. Williamson ◽  
Akshay K. Rathore ◽  
Fariborz Musavi

Geophysics ◽  
1964 ◽  
Vol 29 (2) ◽  
pp. 151-153 ◽  
Author(s):  
Charles C. Bates

A decade ago, it would have been the rare geophysicist indeed who would have predicted that his specialty was destined to become a major topic of discussion between such world political leaders as Presidents Eisenhower and Kennedy, Prime Minister Macmillan of Great Britain, and Chairman Khrushchev of the USSR. Yet this has come to pass during the past six years, for in 1958 there started the continuing round of international negotiations directed towards the creation of an effective underground test-ban treaty. During the conduct of these negotiations, it has been repeatedly necessary to assess the current state-of-the-art in seismology and its sister geophysical sciences, for the only detectable signals known to propagate for several hundreds to thousands of miles from underground nuclear tests are seismic in nature. With the United States policy being only to seek an underground-test-ban agreement incorporating strong safeguards against acts of bad faith, it is important that the political safe-guards be backed up by those of a geophysical nature.


2005 ◽  
Vol 1 (1) ◽  
pp. 101-122 ◽  
Author(s):  
Neha Jain ◽  
Dharma P. Agrawal

The self-organizing nature of sensor networks, their autonomous operation and potential architectural alternatives make them suitable for different data-centric applications. Their wider acceptance seems to be rising on the horizon. In this article, we present an overview of the current state of the art in the field of wireless sensor networks. We also present various open research issues and provide an insight about the latest developments that need to be explored in greater depth that could possibly make this emerging technological area more useful than ever.


2011 ◽  
Vol 11 (2) ◽  
pp. 391-415 ◽  
Author(s):  
Dawn Knight

This paper takes stock of the current state-of-the-art in multimodal corpus linguistics, and proposes some projections of future developments in this field. It provides a critical overview of key multimodal corpora that have been constructed over the past decade and presents a wish-list of future technological and methodological advancements that may help to increase the availability, utility and functionality of such corpora for linguistic research.


2018 ◽  
Vol 61 ◽  
pp. 65-170 ◽  
Author(s):  
Albert Gatt ◽  
Emiel Krahmer

This paper surveys the current state of the art in Natural Language Generation (NLG), defined as the task of generating text or speech from non-linguistic input. A survey of NLG is timely in view of the changes that the field has undergone over the past two decades, especially in relation to new (usually data-driven) methods, as well as new applications of NLG technology. This survey therefore aims to (a) give an up-to-date synthesis of research on the core tasks in NLG and the architectures adopted in which such tasks are organised; (b) highlight a number of recent research topics that have arisen partly as a result of growing synergies between NLG and other areas of artificial intelligence; (c) draw attention to the challenges in NLG evaluation, relating them to similar challenges faced in other areas of NLP, with an emphasis on different evaluation methods and the relationships between them.


2015 ◽  
Author(s):  
Thomas Sloan ◽  
Julio Hernandez-Castro

Steganography is the art and science of concealing information in such a way that only the sender and intended recipient of a message should be aware of its presence. Digital steganography has been used in the past on a variety of media including executable files, audio, text, games and, notably, images. Additionally, there is increasing research interest towards the use of video as a media for steganography, due to its pervasive nature and diverse embedding capabilities. In this work, we examine the embedding algorithms and other security characteristics of several video steganography tools. We show how all feature basic and severe security weaknesses. This is potentially a very serious threat to the security, privacy and anonymity of their users. It is important to highlight that most steganography users have perfectly legal and ethical reasons to employ it. Some common scenarios would include citizens in oppressive regimes whose freedom of speech is compromised, people trying to avoid massive surveillance or censorship, political activists, whistle blowers, journalists, etc. As a result of our findings, we strongly recommend to cease any use of these tools, and to remove any contents that may have been hidden, and any carriers stored, exchanged and/or uploaded online. For many of these tools, carrier files will be trivial to detect, potentially compromising any hidden data and the parties involved in the communication. We finish this work by presenting our steganalytic results, that highlight a very poor current state of the art in practical video steganography tools. There is unfortunately a complete lack of secure and publicly available tools, and even commercial tools offer very poor security. We therefore encourage the steganography community to work towards the development of more secure and accessible video steganography tools, and make them available for the general public. The results presented in this work can also be seen as a useful resource for forensic examiners to determine the existence of any video steganography materials over the course of a computer forensic investigation.


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