scholarly journals Hip Joint Kinematic Covariation During Gait Before and 1-Year After Hip Arthroscopic Surgery for Femoroacetabular Impingement Syndrome

2021 ◽  
Vol 8 ◽  
Author(s):  
Philip Malloy ◽  
Donald Dr. Neumann ◽  
Anne Leung ◽  
Kristof Kipp
Keyword(s):  
Hip Joint ◽  
Arthroscopic Surgery ◽  
Three Dimensional ◽  
Joint Motion ◽  
Healthy Controls ◽  
Motion Coordination ◽  
Time Points ◽  
Coordination Strategy ◽  
Femoroacetabular Impingement Syndrome ◽  
Time Point

The primary aim of this study was to determine if the three-dimensional (3D) hip joint motion coordination during gait changes after arthroscopic surgery for femoroacetabular impingement syndrome (FAIS). Three-dimensional hip joint kinematic data were collected with a 12-camera motion capture system. Five trials of level walking were collected preoperatively (PRE) and at 1-year postoperatively (POST) in 8 patients diagnosed with FAIS and at a single time point in 8 healthy controls. Planar covariation analysis was performed to quantify the 3D hip joint motion coordination strategy during gait. Independent sample's t-test were used to determine differences between the FAIS group at the preoperative time point (PRE) and healthy controls. Paired samples t-tests were used to determine differences between the PRE and POST time points within the FAIS group. The %VAF by PC 1 for the FAIS group at the PRE time point was significantly less than that of healthy controls (PRE: 77.2 ± 8.7% vs. Control: 96.1 ± 2.8%; p = 0.0001), and the % VAF of the second PC (PC2) was significantly greater [PRE: 22.8 (8.7)%; Control: 3.9 (2.8)%; p = 0.0001]. No differences in %VAF were found between the PRE and POST time points within the FAIS group for PC1 [PRE: 77.2 (8.7)% vs. POST: 79.3 (11.1)%; p = 0.472] or PC2 [PRE: 22.7 (8.7)%; POST: 20.7 (11.1)%; p = 0.472]. Significant differences in the plane specific contribution to the 3D motion coordination strategy were found between the FAIS patients at the PRE and POST time points for the sagittal plane [PRE: 5.6 (2.7) vs. POST: 0.91 (6.1); p = 0.012] and frontal plane [PRE: −10.4 (2.2) and −1.5 (6.3); p = 0.005]. Patients with FAIS demonstrated a more complex coordination strategy of 3D hip joint motion than controls and this strategy remains unchanged after hip arthroscopic surgery despite changes in the plane specific contribution to this strategy. These findings indicate that motor control impairments in FAIS patients do exist and seem to persist for at least 1 year after hip arthroscopic surgery.

scholarly journals M224. LONGITUDINAL DETERIORATION OF GESTURE PERFORMANCE IN SCHIZOPHRENIA IS UNRELATED TO SYMPTOM TRAJECTORIES

2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S221-S221
Author(s):  
Anastasia Pavlidou ◽  
Katharina Stegmayer ◽  
Lea Schäppi ◽  
Jeanne Moor ◽  
Sebastian Walther
Keyword(s):  
Social Functioning ◽  
Symptom Severity ◽  
Repeated Measures ◽  
Healthy Controls ◽  
Genetic Liability ◽  
Repeated Measures Anova ◽  
Time Points ◽  
Better Than ◽  
Time Point

Abstract Background Gesture deficits in patients with schizophrenia are highly pronounced, and often linked to poor social functioning, motor abnormalities, and frontal lobe dysfunction. Although gesture performance has been associated to both negative and positive symptoms, its relationship to the severity of these symptoms is still unclear. Here, we examine how gesture performance varies as symptoms change. Furthermore, we aimed to compare gesture performance at two time points to healthy controls and first-degree relatives of schizophrenia patients. Gesture performance in relatives may indicate whether the deficits are associated with genetic liability to schizophrenia. We hypothesize that gesture performance in controls and relatives would be stable; while we expect improvement in patients when symptom severity declines. Methods The present study included 36 patients with schizophrenia (DSM-5 criteria; mean age 35.5 years), 28 unaffected first-degree relatives of schizophrenia patients (mean age 49.9 years) and 38 healthy controls (mean age 39.9 years). All three groups performed the Test for Upper-Limp Apraxia (TULIA), which includes pantomime (performance on verbal command) and imitative (performance upon demonstration) gestures, at two different time points, baseline and re-test (between 1–4 weeks). TULIA performance is recorded on videos and rated blind to diagnosis and stage. In addition, 22 of the 36 patients performed the TULIA at a follow-up session 6-months after baseline. Symptom severity was assessed with the Positive And Negative Syndrome Scale (PANSS). Analysis between the three groups and within patients across the different time points was done using repeated measures ANOVA in R. Results Symptom severity in patients declined between baseline and week 4 (T = 6.7, p<0.001, PANSS total). A 3x2x2 repeated measures ANOVA revealed significant main effects of Group, Type of Gestures, as well as, a significant interaction between Group and Time Point (all F > 3.8; p<0.5) Post hoc analysis, bonferroni corrected, revealed that patients underperformed in both pantomime and imitative gestures compared to healthy controls (p<0.0001) and relatives of schizophrenia patients, although this effect did not reach significance (p=0.26). Performance of pantomime gestures was poorer compared to imitative gestures. Interestingly, this pattern was also observed during the re-test time point (p<0.0001), though gesture performance for imitative gestures significantly declined compared to baseline in patients (p<0.05). In contrast, healthy controls performed better than both patients (p<0.0001) and relatives (p-0.09) and remained stable during the re-test. Likewise, relatives performed intermediate between patients and healthy controls at both time points with scores reaching significance only at re-test (p<0.001). At baseline, imitation was better than pantomime in relatives, but with re-test imitation scores declined while pantomime scores remained stable. Finally, at the 6-month follow-up patients still exhibited lower gesture performance compared to baseline (F=22.25; p<0.05). Discussion Gesture performance in schizophrenia patients remained significantly impaired across time-points, suggesting an extended effect on poor social functioning despite symptom change. In addition, schizophrenia patients and their relatives showed a significant impairment when performing imitative gestures during the re-test compared to baseline. These results call for interventions specifically targeting gesture and social cognition, which would greatly improve patients’ quality of life. Finally, our findings suggest a trait component to gesture behavior that might be linked to genetic liability to psychosis.

scholarly journals Squat and gait biomechanics 6 months following hip arthroscopy for femoroacetabular impingement syndrome

2020 ◽  
Vol 7 (1) ◽  
pp. 27-37
Author(s):  
Gregory L Cvetanovich ◽  
Gary J Farkas ◽  
Edward C Beck ◽  
Philip Malloy ◽  
Kyleen Jan ◽  
...  
Keyword(s):  
Femoroacetabular Impingement ◽  
Hip Arthroscopy ◽  
External Rotation ◽  
T Test ◽  
Impingement Syndrome ◽  
Group Differences ◽  
Healthy Controls ◽  
Joint Mechanics ◽  
Time Points ◽  
Femoroacetabular Impingement Syndrome

Abstract The purpose of this study was to (i) assess whether squat and gait biomechanical measures improve in patients with femoroacetabular impingement syndrome (FAIS) 6 months after surgery compared to pre-operative measures and (ii) compare biomechanical properties to controls without FAIS. In this prospective study, biomechanical data during a double leg squat task and gait for 15 FAIS patients and 9 controls were collected using three-dimensional motion analysis. Data were collected in the FAIS group at two-time points, pre-operatively and 6-month post-operatively following arthroscopic hip surgery, and at a single time point for the healthy controls. Independent sample’s t-test were used to compare the FAIS group to the controls, and paired samples t-test were used to determine within-group differences before and after hip arthroscopy in the FAIS group. The results indicated that there were significant within-group increases for sagittal plane moment rate during the double leg squat task (P = 0.009) between the pre-operative and post-operative time points for the FAIS group. Between-group differences showed that FAIS patients pre-operatively exhibit slower squat velocities during the descent (P = 0.005) and ascent phase (P = 0.012) of a double leg squat when compared healthy controls. Reduced hip external rotation moments during gait (P = 0.02) were also found between FAIS patients pre-operatively and controls. In conclusion, alterations in hip biomechanics are present before surgery for FAIS when compared to healthy controls, and joint mechanics change 6 months after surgery. However, the biomechanical differences during a double leg squat and gait were minimal. 

An innovative method for the three-dimensional study of hip joint motion

2014 ◽  
Vol 17 (sup1) ◽  
pp. 56-57 ◽  
Author(s):  
N. Bonneau ◽  
J. Bouhallier ◽  
M. Haeusler ◽  
O. Gagey
Keyword(s):  
Hip Joint ◽  
Three Dimensional ◽  
Joint Motion ◽  
Innovative Method

scholarly journals Magnetic Resonance Imaging of the Hips of Runners Before and After Their First Marathon Run: Effect of Training for and Completing a Marathon

2021 ◽  
Vol 9 (7) ◽  
pp. 232596712110104
Author(s):  
Laura M. Horga ◽  
Johann Henckel ◽  
Anastasia Fotiadou ◽  
Anna Di Laura ◽  
Anna C. Hirschmann ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Bone Marrow ◽  
Magnetic Resonance ◽  
Training Program ◽  
Hip Joint ◽  
Marathon Running ◽  
Resonance Imaging ◽  
Time Points ◽  
Before And After ◽  
Time Point

Background: No studies have focused on magnetic resonance imaging (MRI) of the hips of marathoners, despite the popularity and injury risks of marathon running. Purpose: To understand the effect of preparing for and completing a marathon run (42 km) on runners’ hip joints by comparing MRI findings before and after their first marathon. Study Design: Case-control study; Level of evidence, 3. Methods: A total of 28 healthy adults (14 males, 14 females; mean age, 32.4 years) were recruited after registering for their first marathon. They underwent 3-T MRI of both hips at 16 weeks before (time point 1) and 2 weeks after the marathon (time point 2). After the first MRI, 21 runners completed the standardized, 4 month--long training program and the marathon; 7 runners did not complete the training or the marathon. Specialist musculoskeletal radiologists reported and graded the hip joint structures using validated scoring systems. Participants completed the Hip disability and Osteoarthritis Outcome Score (HOOS) at both imaging time points. Results: At time point 1, MRI abnormalities of the hip joint were seen in 90% of participants and were located in at least 1 of these areas: labrum (29%), articular cartilage (7%), subchondral bone marrow (14%), tendons (17%), ligaments (14%), and muscles (31% had moderate muscle atrophy). At time point 2, only 2 of the 42 hips showed new findings: a small area of mild bone marrow edema appearance (nonweightbearing area of the hip and not attributable to running). There was no significant difference in HOOS between the 2 time points. Only 1 participant did not finish the training because of hip symptoms and thus did not run the marathon; however, symptoms resolved before the MRI at time point 2. Six other participants discontinued their training because of non–hip related issues: a knee injury, skin disease, a family bereavement, Achilles tendon injury, illness unrelated to training, and a foot injury unrelated to training. Conclusion: Runners who completed a 4-month beginner training program before their first marathon run, plus the race itself, showed no hip damage on 3-T MRI scans.

scholarly journals Cytotoxicity assessment of different doses of ozonated water on dental pulp cells

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ferdiye Küçük ◽  
Sibel Yıldırım ◽  
Serap Çetiner
Keyword(s):  
Cell Viability ◽  
Repeated Measures ◽  
Dental Pulp ◽  
Control Group ◽  
Dental Pulp Cells ◽  
Time Points ◽  
Significant Difference ◽  
Pulp Cells ◽  
Time Point ◽  
Ozonated Water

Abstract Background The purpose of this study was to assess the cytotoxicity of various concentrations of ozonated water (OW) on human primary dental pulp cells. Methods Human primary dental pulp cells were isolated from exfoliated primary canine teeth of an 11-year-old patient with good systemic and oral health. Afterwards, cells were divided into 6 experimental groups; four groups of OW in concentrations of 2 mg/L, 4 mg/L, 8 mg/L, and 16 mg/L, untreated control group, and cell culture without cells. Cytotoxicity was evaluated after exposure for 5-min exposure using Mosmann’s Tetrazolium Toxicity (MTT) assay at 0 h and 48 h time points. Data were analyzed using a repeated measures analysis of variance and Post-hoc tests were performed using Bonferroni correction for multiple comparisons. Results All experimental groups showed proliferation at 0 h time point. However, all groups also experienced a decrease in overtime at 48 h time point (p < 0.05). At both time points 2 mg/L OW showed the highest cell viability as well as proliferation. At 0 h time point, the increase in cell viability for all experimental groups was found statistically significant when compared to positive control group (p < 0.05). At 48 h time point, although 8 mg/L and 16 mg/L OW showed statistically significant reduction in compare to 0 h time point, 2 mg/L and 4 mg/L OW groups didn’t experience any statistically significant difference (p < 0.05). Conclusion Considering our findings, due to ozonated water's induced a higher proliferation rate of dental pulp cells, indicating their biocompatibility and a possible adjuvant on irrigating agent in regenerative endodontic procedures.

scholarly journals Levels of physical activity in four domains and affective wellbeing before and during the Covid-19 pandemic

2021 ◽  
Vol 79 (1) ◽  
Author(s):  
Eliane S. Engels ◽  
Michael Mutz ◽  
Yolanda Demetriou ◽  
Anne K. Reimers
Keyword(s):  
Mental Health ◽  
Physical Activity ◽  
Protective Factor ◽  
Total Sample ◽  
Poor Mental Health ◽  
German Population ◽  
Time Points ◽  
Sport And Exercise ◽  
Over Time ◽  
Time Point

Abstract Background Latest studies indicated that the general mental health level is low during the pandemic. Probably, this deterioration of the mental health situation is partly due to declines in physical activity. The aim of this study was to investigate differences in and the association between affective wellbeing and levels of different domains of physical activity at three time points before and during the pandemic. Method We used a nationwide online panel with a trend data design encompassing a total sample of N = 3517, representing the German population (> 14 years). Four different activity domains (sport and exercise, light outdoor activity, housework/gardening, active travel) and affective wellbeing (positive and negative affect) were assessed at three time points before and during the Covid-19 pandemic (October 2019, March 2020, October 2020). Results Multivariate analyses of variance (MANOVA) indicate differences regarding affective wellbeing over the three time points with the lowest values at the second time point. Levels of activity in the four domains differed significantly over time with the strongest decrease for sport and exercise from the first to the second time point. Partial correlations indicated that the relationships between sport and exercise and positive affect were most consistent over time. Conclusions Overall, our findings suggest that physical activity plays a particularly important role in the pandemic period as a protective factor against poor mental health. Especially sports and exercise seem to be supportive and should be encouraged, e.g. by providing additional support in finding adequate outdoor, home-based or digital substitutes.

scholarly journals Developmental features and predicting airway failure risk in critically ill children with mandibular hypoplasia using 3D computational tomographic analysis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Doo-Hwan Kim ◽  
Eunseo Gwon ◽  
Junheok Ock ◽  
Jong-Woo Choi ◽  
Jee Ho Lee ◽  
...  
Keyword(s):  
Risk Factors ◽  
Difficult Airway ◽  
Hyoid Bone ◽  
Three Dimensional ◽  
Upper Airway ◽  
Critically Ill Children ◽  
Healthy Controls ◽  
Mandibular Hypoplasia ◽  
Tongue Position ◽  
Developmental Features

AbstractIn children with mandibular hypoplasia, airway management is challenging. However, detailed cephalometric assessment data for this population are sparse. The aim of this study was to find risk factors for predicting difficult airways in children with mandibular hypoplasia, and compare upper airway anatomical differences using three-dimensional computed tomography (3D CT) between children with mandibular hypoplasia and demographically matched healthy controls. There were significant discrepancies in relative tongue position (P < 0.01) and anterior distance of the hyoid bone (P < 0.01) between patients with mandibular hypoplasia and healthy controls. All mandibular measures were significantly different between the two groups, except for the height of the ramus of the mandible. After adjusting for age and sex, the anterior distance of hyoid bone and inferior pogonial angle were significantly associated with a difficult airway (P = 0.01 and P = 0.02). Quantitative analysis of upper airway structures revealed significant discrepancies, including relative tongue position, hyoid distance, and mandible measures between patients with mandibular hypoplasia and healthy controls. The anterior distance of the hyoid bone and inferior pogonial angle may be risk factors for a difficult airway in patients with mandibular hypoplasia.

scholarly journals Propagation of Voltage Deviations in a Power System

Electronics ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 949
Author(s):  
Tomasz Okon ◽  
Kazimierz Wilkosz
Keyword(s):  
Power System ◽  
Case Studies ◽  
Measurement Data ◽  
Theoretical Background ◽  
Original Method ◽  
Operational Experience ◽  
Remedial Measures ◽  
Time Points ◽  
General Candidate ◽  
Time Point

The paper deals with voltage profiles in a power system. The analysis of these profiles is important due to the requirement that the Root-Mean-Squared (RMS) values of nodal voltages should be within certain ranges, as well as to ensure desired power flows in a power system. In both cases, it is desirable to indicate points in a power system where it is reasonable to apply remedial measures to meet the requirements for RMS values of nodal voltages, or to effectively control the power flows in a power system. In general, candidate nodes for remediation are established based on operational experience or measurement data from a certain time point (sometimes from several time points). The paper presents a method that provides a basis for determining the aforementioned candidate nodes based on the behavior of a system over a certain period of time, which is an unquestionable advantage of this proposal. In order to achieve the abovementioned goal, the method provides for the analysis of propagation of voltage RMS value deviations in a power system. The analysis of correlational relationships between the RMS values of nodal voltages is used for this. After presentation of the theoretical background, the new original method is described in the paper. Then, case studies showing the utilization of that method are presented. At the end of the paper, features of the proposed method are enumerated.

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