scholarly journals Paratuberculosis: The Hidden Killer of Small Ruminants

Animals ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 12
Author(s):  
Sanaa M. Idris ◽  
Kamal H. Eltom ◽  
Julius B. Okuni ◽  
Lonzy Ojok ◽  
Wisal A. Elmagzoub ◽  
...  

Paratuberculosis (PTB) is a contagious and chronic enteric disease of ruminants and many non-ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP), and is characterised by diarrhoea and progressive emaciation with consequent serious economic losses due to death, early culling, and reduced productivity. In addition, indirect economic losses may arise from trade restrictions. Besides being a production limiting disease, PTB is a potential zoonosis; MAP has been isolated from Crohn’s disease patients and was associated with other human diseases, such as rheumatoid arthritis, Hashimoto’s thyroiditis, Type 1 diabetes, and multiple sclerosis. Paratuberculosis in sheep and goats may be globally distributed though information on the prevalence and economic impact in many developing countries seem to be scanty. Goats are more susceptible to infection than sheep and both species are likely to develop the clinical disease. Ingestion of feed and water contaminated with faeces of MAP-positive animals is the common route of infection, which then spreads horizontally and vertically. In African countries, PTB has been described as a “neglected disease”, and in small ruminants, which support the livelihood of people in rural areas and poor communities, the disease was rarely reported. Prevention and control of small ruminants’ PTB is difficult because diagnostic assays demonstrate poor sensitivity early in the disease process, in addition to the difficulties in identifying subclinically infected animals. Further studies are needed to provide more insight on molecular epidemiology, transmission, and impact on other animals or humans, socio-economic aspects, prevention and control of small ruminant PTB.

2020 ◽  
Author(s):  
Peter Nyasulu ◽  
Jacqueline Weyer ◽  
Rea Tschopp ◽  
Adane Mihret ◽  
Abraham Aseffa ◽  
...  

Background: Rabies a neglected tropical disease, mostly affecting poor and vulnerable populations living in remote rural areas in developing countries. The disease continues to pose a significant public health a threat with an estimated 59,000 dog-transmitted human deaths, of which an estimated 21,476 human deaths occur in Africa each year. The global strategy has been set by the quartite World Health Organization (WHO), the World Organization for Animal Health (OIE), the Food and Agriculture Organization of the United Nations (FAO) and the Global Alliance for Rabies Control (GARC), aiming for "zero human deaths associated with dog transmitted rabies by 2030". African countries, however, face several challenges and there are still gaps in controlling rabies. The aim of this study review is to determine rabies prevalence, mortality and associated risk factors in both human population and animal population and to evaluate the presence or absence of integrated one health surveillance response in African nations. Methods and analysis: We will conduct an electronic literature searches on PubMed, CINAHL, (Cumulative Index of Nursing and Allied Health Literature), Scopus, and Web of Science and other relevant databases. Reference lists from identified published articles or reviews and conference abstracts will also be searched for relevant articles. Published and unpublished literatures (grey) will be included in the search. The findings will be presented graphically in terms of mortality, morbidity, interventions for rabies control in Africa, research gaps identified, available research evidence, rabies surveillance, prevention and control and adverse events. Conclusion: This review will contribute to the coordination of interventions for surveillance, prevention, and control with African countries as country-based gaps and challenges and opportunities will be highlighted. In addition, the scaling up of post-exposure prophylaxis (PEP rabies will be evaluated in African countries and the projection to achieve the target of "zero deaths of human rabies by 2030" in Africa.


2020 ◽  
Author(s):  
Peter Nyasulu ◽  
Jacqueline Weyer ◽  
Rea Tschopp ◽  
Adane Mihret ◽  
Samuel Victor Nuvor ◽  
...  

Abstract Background: Rabies a neglected tropical disease, mostly affecting poor and vulnerable populations living in remote rural areas in developing countries. The disease continues to pose a significant public health a threat with an estimated 59,000 dog-transmitted human deaths, of which an estimated 21,476 human deaths occur in Africa each year. The global strategy has been set by the quartite World Health Organization (WHO), the World Organization for Animal Health (OIE), the Food and Agriculture Organization of the United Nations (FAO) and the Global Alliance for Rabies Control (GARC), aiming for "zero human deaths associated with dog transmitted rabies by 2030". African countries, however, face several challenges and there are still gaps in controlling rabies. The aim of this study review is to determine rabies prevalence, mortality and associated risk factors in both human population and animal population and to evaluate the presence or absence of integrated one health surveillance response in African nations.Methods and analysis: We will conduct an electronic literature searches on PubMed, CINAHL, (Cumulative Index of Nursing and Allied Health Literature), Scopus, and Web of Science and other relevant databases. Reference lists from identified published articles or reviews and conference abstracts will also be searched for relevant articles. Published and unpublished literatures (grey) will be included in the search. The findings will be presented graphically in terms of mortality, morbidity, interventions for rabies control in Africa, research gaps identified, available research evidence, rabies surveillance, prevention and control and adverse events.Conclusion: This review will contribute to the coordination of interventions for surveillance, prevention, and control with African countries as country-based gaps and challenges and opportunities will be highlighted. In addition, the scaling up of post-exposure prophylaxis (PEP rabies will be evaluated in African countries and the projection to achieve the target of "zero deaths of human rabies by 2030" in Africa.


2021 ◽  
Author(s):  
Yunyun Yan ◽  
Teng-yang Fan ◽  
Yan-ling Zheng ◽  
Hai-qin Yang ◽  
Tian-shu Li ◽  
...  

Abstract Background In fulfilling the COVID-19 containment, primary health care (PHC) facilities in China played an important role. We sought to investigate the exact tasks performed at the PHC facilities and the processes of COVID-19 prevention and control.Methods Semi-structured face-to-face interviews for primary care physicians (PCPs) and a simple survey for residents were conducted in the field survey. Based-on purposive stratified sampling, 32 PCPs were selected from 22 PHC facilities in Wuhan as a high-risk city, in Shanghai as medium-risk city and in Zunyi as low-risk city. In the field survey, semi-structured face-to-face interviews were conducted with PCPs to summarize the tasks of COVID-19 prevention and control at the PHC facilities. A simple survey was used to investigate the local residents’ awareness about COVID-19 prevention and control.Results In pre-outbreak period, the PHC facilities mainly engaged in storing medical supplies; in out-break period, they were responsible for screening, transferring, quarantine and treatment; in regular prevention and control period, attention was given to the employees and items of cold-chain & fresh food markets, etc. In Wuhan, PHC facilities focused on graded diagnoses and treatments of patients; in Shanghai, they were mainly engaged in at-home/centralized quarantine; in Zunyi, they focused on the screening of high-risk individuals. In urban areas, COVID-19 were more likely to be transmitted; in urban-rural areas, it was difficult to perform screening on the migrant populations; in rural areas, the risk was much lower. The community residents had satisfactory compliance with the preventive measures.Conclusion We identified differences in the prevention and control tasks performed at the PHC facilities in China. During the different phases of the pandemic, the tasks were adjusted depending on the gradually comprehensive understanding of COVID-19. Among the cities at different risk levels, screening, quarantine, transferring or treatment was chosen to be a priority accordingly. Located in different intra-city geographic locations at different risk levels, the PHC facilities conducted their own tasks accordingly. Additionally, compliance on the part of the local community residents could not be overemphasized in COVID-19 prevention and control.


2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Ali Asghar Mozaffari ◽  
Saeedeh Shojaeepour ◽  
Shahin Ghahremani Ghareh Cheshmeh

The sheep nasal bot, Oestrus ovis (Diptera: Oestridae), is a cosmopolitan parasite commonly found in sheep and occasionally goats. Rarely a bot will migrate into the sheep brain (false gid). Following the complaint of an animal husbandman about high mortality rate in a sheep herd, the herd was clinically, hematologically, and pathologically examined exactly. Clinical, hematological, and pathological findings were described in the text. Necropsy findings showed heavy infestation with Oestrus ovis larvae. The herd was treated with Ivermectin. After treatment all patients without nervous sings were recovered. Patients with nervous signs did not respond to treatment, but new cases of disease did not occur and the mortality stopped. In the present report, a high mortality rate due to false gid in a sheep herd was described. The prevention and control of the disease are important because of economic losses and the possibility of transmission to the human.


2020 ◽  
Vol 0 ◽  
pp. 1-5
Author(s):  
Praveen Kulkarni ◽  
D. Sunil Kumar ◽  
Siddalingappa Hugara ◽  
Renuka Manjunath ◽  
M. R. Narayana Murthy

Objectives: Dengue, among all the vector-borne diseases, continues to be a major public health problem in India. Dengue once considered being problem in urban areas, now it is increasingly found in rural areas. Thus, empowering the village level functionaries like members of Village Health Sanitation and Nutrition Committee (VHSNC) can help in prevention and control of dengue in the rural areas. The present study was conducted to assess the effectiveness of educational intervention on perception regarding dengue and its prevention among VHSNC members. Material and Methods: This prospective interventional study was conducted among all 305 VHSNC members of two randomly selected primary health centers of Mysuru talukas for the period of 6 months. Baseline levels of perception on dengue were collected using a pre-tested structured questionnaire. Educational intervention on various domains of dengue and its prevention was provided using audiovisual aids, handouts, and group discussion. Endline survey was conducted 1 month after the education sessions to assess the effectiveness intervention. Results: A total of 305 VHSNC members participated in the study. In pre-test survey, only 189 (61.9%) had ever heard of disease dengue. In post-test survey, 274 (91.3%) had heard of dengue. There was a statistically significant improvement in perception regarding, preventable nature of dengue, mode of transmission, breeding and biting habits of mosquito, source reduction measures, and personal protective measures against mosquito bites following educational intervention. Conclusion: Educational intervention was found to be effective in empowering village level stake holders like VHSNC members regarding dengue and its prevention.


2020 ◽  
Vol 16 (01) ◽  
pp. 62-65
Author(s):  
Mahesh Chander ◽  
MS Kannadhasan ◽  
D Bardhan

Migratory sheep, due to its movement, poses threat of spreading diseases among small ruminants. Considering this, the study was carried out to identify the focus area of extension intervention among the migratory sheep farmers to disseminate scientifically recommended practices which minimize disease risk and enhance flock health. The study was conducted following ex post fact research design at Venganur village, Cuddalore district, Tamil Nadu. Using a semi-structured interview schedule, data were personally collected from 30 migratory sheep farmers who were selected purposively. The findings were subjected to focussed group interview involving seven farmers. The results envisaged a wider difference among the farmers from 100 per cent non-adoption of balanced ration to 100.00 per cent adoption of deworming. Therefore, extension interventions need to be intensified to educate the farmers on technologies which help in disease prevention and control.


2020 ◽  
Author(s):  
Joseph Kawuki ◽  
Taha Hussein Musa ◽  
Shireen Salome Papabathini ◽  
Upama Ghimire ◽  
Nathan Obore ◽  
...  

Abstract Background: The achievements in Ebola virus disease (EVD) prevention and control can be reflected by scientific studies, particularly in the top-cited studies. The study thus aimed to identify and characterise the 100 top-cited studies of Ebola.Methods: The study used a retrospective bibliometric analysis, which was performed in January 2020. Studies were searched from the Web of Science using the keywords: “Ebola” or “Ebola virus” or “Ebola virus disease” to identify the 100 top-cited ebola studies. Studies were analysed for the number of citations, authorship, and journal, year of publication, country and institution. The analyses were carried out using SPSS, HistCite and VOSviewer.Results: The 100 top-cited studies were published between 1977 and 2017, were cited from 169 to 808 times and had an average citation of 290.5, and 8 studies were cited more than 500 times. They were published in 31 journals, and Journal of Virology published most of the studies (n=14). They were produced by 33 countries, and the USA published most of the studies (63), followed by Germany (8) and Gabon (6). Centre for Disease prevention and Control-USA (26) was the leading institution, while Geisbert TW and Sanchez A were the most productive authors.Conclusions: This study provides insights into the historical advancements reflected by the top-cited studies and has highlighted the leading roles played by various stakeholders in addressing EVD. However, the contribution of African countries is not sufficiently reflected among these studies, and so more focus, funding and involvement in clinical research is needed for effective prevention and control of EVD in Africa.


2018 ◽  
Vol 63 (2) ◽  
pp. 232-243 ◽  
Author(s):  
V.M. Vaidya ◽  
R.J. Zende ◽  
A.M. Paturkar ◽  
M.L. Gatne ◽  
D.G. Dighe ◽  
...  

AbstractEchinococcosis/hydatidosis which is a neglected parasitic zoonosis in the developing country like India. The study was conducted during April, 2010 to March, 2017 to determine the prevalence among slaughtered food animals, dogs and human. The samples were collected from the various slaughterhouses situated in different regions of Maharashtra state. A total of 9464 cattle (male), 3661 buffalo, 47189 sheep, 33350 goats and 13579 pigs were scientifically examined during PM inspection at different slaughterhouses. The study revealed that the prevalence of disease in cattle (3.00%) was highest followed by buffalo (2.05%), pig (1.28%), sheep (0.09%) and goat (0.01%), by PM examination. The average estimated economic losses (direct and indirect) due to hydatidosis were Rs. 8,65,83,566 in cattle, Rs. 44,33,93,900 in buffalo, Rs. 7,24,50,615 in sheep, Rs. 1,88,29,359 in goat and Rs. 5,20,49,081 in pigs. Dog faecal samples analyzed and showed the prevalence of echinococcosis as 4.34% (19/438) by sedimentation method and positive samples were confirmed by PCR assay, whereas in high risk human, 11.09% sera samples were found to be positive for echinococcosis. However, based on data collection for seven years, 58 patients were found to be surgically operated for hydatid cyst removal. The results of the present study indicated that cystic echinococcosis/hydatidosis is prevalent in both human and animal population in study areas which attracts serious attention from veterinary and public health authority to reduce economic burden and in designing appropriate strategy for prevention and control of disease.


Sign in / Sign up

Export Citation Format

Share Document