scholarly journals Hyperspectral Reflectance Imaging Combined with Multivariate Analysis for Diagnosis of Sclerotinia Stem Rot on Arabidopsis Thaliana Leaves

2019 ◽  
Vol 9 (10) ◽  
pp. 2092 ◽  
Author(s):  
Jing Liang ◽  
Xiaoli Li ◽  
Panpan Zhu ◽  
Ning Xu ◽  
Yong He

Sclerotinia stem rot (SSR) is one of the most destructive diseases in the world caused by Sclerotinia sclerotiorum (S. sclerotiorum), resulting in significant yield loss. Early and high-throughput detection would be critical to prevent SSR from spreading. This study aimed to propose a feasible method for SSR detection based on the hyperspectral imaging coupled with multivariate analysis. The performance of different detecting algorithms were compared by combining the extreme learning machine (ELM), K-nearest neighbor algorithm (KNN), linear discriminant analysis (LDA), naïve Bayes classifier (NB) and the support vector machine (SVM) with the random frog (RF), successive projection algorithm (SPA) and sequential forward selection (SFS). The similarity of selected optimal wavelengths by three different feature selection methods indicated a high correlation between selected wavelengths and SSR. Compared with KNN, LDA, NB, and SVM, three wavelengths (455, 671 and 747 nm) selected by SFS-CA combined with ELM could achieve relatively better results with the overall accuracy of 93.7% and the lowest false negative rate of 2.4%. These results demonstrated the potential of the presented method using hyperspectral reflectance imaging combined with multivariate analysis for SSR diagnosis.

2019 ◽  
Vol 20 (5) ◽  
pp. 488-500 ◽  
Author(s):  
Yan Hu ◽  
Yi Lu ◽  
Shuo Wang ◽  
Mengying Zhang ◽  
Xiaosheng Qu ◽  
...  

Background: Globally the number of cancer patients and deaths are continuing to increase yearly, and cancer has, therefore, become one of the world&#039;s highest causes of morbidity and mortality. In recent years, the study of anticancer drugs has become one of the most popular medical topics. </P><P> Objective: In this review, in order to study the application of machine learning in predicting anticancer drugs activity, some machine learning approaches such as Linear Discriminant Analysis (LDA), Principal components analysis (PCA), Support Vector Machine (SVM), Random forest (RF), k-Nearest Neighbor (kNN), and Naïve Bayes (NB) were selected, and the examples of their applications in anticancer drugs design are listed. </P><P> Results: Machine learning contributes a lot to anticancer drugs design and helps researchers by saving time and is cost effective. However, it can only be an assisting tool for drug design. </P><P> Conclusion: This paper introduces the application of machine learning approaches in anticancer drug design. Many examples of success in identification and prediction in the area of anticancer drugs activity prediction are discussed, and the anticancer drugs research is still in active progress. Moreover, the merits of some web servers related to anticancer drugs are mentioned.


2018 ◽  
Vol 61 (5) ◽  
pp. 1497-1504
Author(s):  
Zhenjie Wang ◽  
Ke Sun ◽  
Lihui Du ◽  
Jian Yuan ◽  
Kang Tu ◽  
...  

Abstract. In this study, computer vision was used for the identification and classification of fungi on moldy paddy. To develop a rapid and efficient method for the classification of common fungal species found in stored paddy, computer vision was used to acquire images of individual colonies of growing fungi for three consecutive days. After image processing, the color, shape, and texture features were acquired and used in a subsequent discriminant analysis. Both linear (i.e., linear discriminant analysis and partial least squares discriminant analysis) and nonlinear (i.e., random forest and support vector machine [SVM]) pattern recognition models were employed for the classification of fungal colonies, and the results were compared. The results indicate that when using all of the features for three consecutive days, the performance of the nonlinear tools was superior to that of the linear tools, especially in the case of the SVM models, which achieved an accuracy of 100% on the calibration sets and an accuracy of 93.2% to 97.6% on the prediction sets. After sequential selection of projection algorithm, ten common features were selected for building the classification models. The results showed that the SVM model achieved an overall accuracy of 95.6%, 98.3%, and 99.0% on the prediction sets on days 2, 3, and 4, respectively. This work demonstrated that computer vision with several features is suitable for the identification and classification of fungi on moldy paddy based on the form of the individual colonies at an early growth stage during paddy storage. Keywords: Classification, Computer vision, Fungal colony, Feature selection, SVM.


2020 ◽  
Author(s):  
Nazrul Anuar Nayan ◽  
Hafifah Ab Hamid ◽  
Mohd Zubir Suboh ◽  
Noraidatulakma Abdullah ◽  
Rosmina Jaafar ◽  
...  

Abstract Background: Cardiovascular disease (CVD) is the leading cause of deaths worldwide. In 2017, CVD contributed to 13,503 deaths in Malaysia. The current approaches for CVD prediction are usually invasive and costly. Machine learning (ML) techniques allow an accurate prediction by utilizing the complex interactions among relevant risk factors. Results: This study presents a case–control study involving 60 participants from The Malaysian Cohort, which is a prospective population-based project. Five parameters, namely, the R–R interval and root mean square of successive differences extracted from electrocardiogram (ECG), systolic and diastolic blood pressures, and total cholesterol level, were statistically significant in predicting CVD. Six ML algorithms, namely, linear discriminant analysis, linear and quadratic support vector machines, decision tree, k-nearest neighbor, and artificial neural network (ANN), were evaluated to determine the most accurate classifier in predicting CVD risk. ANN, which achieved 90% specificity, 90% sensitivity, and 90% accuracy, demonstrated the highest prediction performance among the six algorithms. Conclusions: In summary, by utilizing ML techniques, ECG data can serve as a good parameter for CVD prediction among the Malaysian multiethnic population.


Sensors ◽  
2019 ◽  
Vol 19 (12) ◽  
pp. 2814 ◽  
Author(s):  
Xiaoguang Liu ◽  
Huanliang Li ◽  
Cunguang Lou ◽  
Tie Liang ◽  
Xiuling Liu ◽  
...  

Falls are the major cause of fatal and non-fatal injury among people aged more than 65 years. Due to the grave consequences of the occurrence of falls, it is necessary to conduct thorough research on falls. This paper presents a method for the study of fall detection using surface electromyography (sEMG) based on an improved dual parallel channels convolutional neural network (IDPC-CNN). The proposed IDPC-CNN model is designed to identify falls from daily activities using the spectral features of sEMG. Firstly, the classification accuracy of time domain features and spectrograms are compared using linear discriminant analysis (LDA), k-nearest neighbor (KNN) and support vector machine (SVM). Results show that spectrograms provide a richer way to extract pattern information and better classification performance. Therefore, the spectrogram features of sEMG are selected as the input of IDPC-CNN to distinguish between daily activities and falls. Finally, The IDPC-CNN is compared with SVM and three different structure CNNs under the same conditions. Experimental results show that the proposed IDPC-CNN achieves 92.55% accuracy, 95.71% sensitivity and 91.7% specificity. Overall, The IDPC-CNN is more effective than the comparison in accuracy, efficiency, training and generalization.


Author(s):  
Nayan Nazrul Anuar ◽  
Ab Hamid Hafifah ◽  
Suboh Mohd Zubir ◽  
Abdullah Noraidatulakma ◽  
Jaafar Rosmina ◽  
...  

<p>Cardiovascular disease (CVD) is the leading cause of deaths worldwide. In 2017, CVD contributed to 13,503 deaths in Malaysia. The current approaches for CVD prediction are usually invasive and costly. Machine learning (ML) techniques allow an accurate prediction by utilizing the complex interactions among relevant risk factors. This study presents a case–control study involving 60 participants from The Malaysian Cohort, which is a prospective population-based project. Five parameters, namely, the R–R interval and root mean square of successive differences extracted from electrocardiogram (ECG), systolic and diastolic blood pressures, and total cholesterol level, were statistically significant in predicting CVD. Six ML algorithms, namely, linear discriminant analysis, linear and quadratic support vector machines, decision tree, k-nearest neighbor, and artificial neural network (ANN), were evaluated to determine the most accurate classifier in predicting CVD risk. ANN, which achieved 90% specificity, 90% sensitivity, and 90% accuracy, demonstrated the highest prediction performance among the six algorithms. In summary, by utilizing ML techniques, ECG data can serve as a good parameter for CVD prediction among the Malaysian multiethnic population.</p>


Signals ◽  
2020 ◽  
Vol 1 (2) ◽  
pp. 188-208
Author(s):  
Mert Sevil ◽  
Mudassir Rashid ◽  
Mohammad Reza Askari ◽  
Zacharie Maloney ◽  
Iman Hajizadeh ◽  
...  

Wearable devices continuously measure multiple physiological variables to inform users of health and behavior indicators. The computed health indicators must rely on informative signals obtained by processing the raw physiological variables with powerful noise- and artifacts-filtering algorithms. In this study, we aimed to elucidate the effects of signal processing techniques on the accuracy of detecting and discriminating physical activity (PA) and acute psychological stress (APS) using physiological measurements (blood volume pulse, heart rate, skin temperature, galvanic skin response, and accelerometer) collected from a wristband. Data from 207 experiments involving 24 subjects were used to develop signal processing, feature extraction, and machine learning (ML) algorithms that can detect and discriminate PA and APS when they occur individually or concurrently, classify different types of PA and APS, and estimate energy expenditure (EE). Training data were used to generate feature variables from the physiological variables and develop ML models (naïve Bayes, decision tree, k-nearest neighbor, linear discriminant, ensemble learning, and support vector machine). Results from an independent labeled testing data set demonstrate that PA was detected and classified with an accuracy of 99.3%, and APS was detected and classified with an accuracy of 92.7%, whereas the simultaneous occurrences of both PA and APS were detected and classified with an accuracy of 89.9% (relative to actual class labels), and EE was estimated with a low mean absolute error of 0.02 metabolic equivalent of task (MET).The data filtering and adaptive noise cancellation techniques used to mitigate the effects of noise and artifacts on the classification results increased the detection and discrimination accuracy by 0.7% and 3.0% for PA and APS, respectively, and by 18% for EE estimation. The results demonstrate the physiological measurements from wristband devices are susceptible to noise and artifacts, and elucidate the effects of signal processing and feature extraction on the accuracy of detection, classification, and estimation of PA and APS.


Author(s):  
Mahmood I. Alhusseini ◽  
Firas Abuzaid ◽  
Albert J. Rogers ◽  
Junaid A.B. Zaman ◽  
Tina Baykaner ◽  
...  

Background: Advances in ablation for atrial fibrillation (AF) continue to be hindered by ambiguities in mapping, even between experts. We hypothesized that convolutional neural networks (CNN) may enable objective analysis of intracardiac activation in AF, which could be applied clinically if CNN classifications could also be explained. Methods: We performed panoramic recording of bi-atrial electrical signals in AF. We used the Hilbert-transform to produce 175 000 image grids in 35 patients, labeled for rotational activation by experts who showed consistency but with variability (kappa [κ]=0.79). In each patient, ablation terminated AF. A CNN was developed and trained on 100 000 AF image grids, validated on 25 000 grids, then tested on a separate 50 000 grids. Results: In the separate test cohort (50 000 grids), CNN reproducibly classified AF image grids into those with/without rotational sites with 95.0% accuracy (CI, 94.8%–95.2%). This accuracy exceeded that of support vector machines, traditional linear discriminant, and k-nearest neighbor statistical analyses. To probe the CNN, we applied gradient-weighted class activation mapping which revealed that the decision logic closely mimicked rules used by experts (C statistic 0.96). Conclusions: CNNs improved the classification of intracardiac AF maps compared with other analyses and agreed with expert evaluation. Novel explainability analyses revealed that the CNN operated using a decision logic similar to rules used by experts, even though these rules were not provided in training. We thus describe a scaleable platform for robust comparisons of complex AF data from multiple systems, which may provide immediate clinical utility to guide ablation. Registration: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT02997254. Graphic Abstract: A graphic abstract is available for this article.


Electroencephalographic (EEG) signals are the preferred input for non-invasive Brain-Computer Interface (BCI). Efficient signal processing strategies, including feature extraction and classification, are required to distinguish the underlying task of BCI. This work proposes the optimized common spatial pattern(CSP) filtering technique as the feature extraction method for collecting the spatially spread variation of the signal. The bandpass filter (BPF) designed for this work assures the availability of event-related synchronized (ERS) and event-related desynchronized (ERD) signal as input to the spatial filter. This work takes consideration of the area-specific electrodes for feature formation. This work further proposes a comparative analysis of classifier algorithms for classification accuracy(CA), sensitivity and specificity and the considered algorithms are Support Vector Machine(SVM), Linear Discriminant Analysis(LDA), and K-Nearest Neighbor(KNN). Performance parameters considered are CA, sensitivity, and selectivity, which can judge the method not only for high CA but also inclining towards the particular class. Thus it will direct in the selection of appropriate classifier as well as tuning the classifier to get the balanced results. In this work, CA, the prior performance parameter is obtained to be 88.2% sensitivity of 94.2% and selectivity 82.2% for the cosine KNN classifier. SVM with linear kernel function also gives the comparable results, thus concluding that the robust classifiers perform well for all parameters in case of CSP for feature extraction.


2021 ◽  
Author(s):  
Monika Jyotiyana ◽  
Nishtha Kesswani ◽  
Munish Kumar

Abstract Deep learning techniques are playing an important role in the classification and prediction of diseases. Undoubtedly deep learning has a promising future in the health sector, especially in medical imaging. The popularity of deep learning approaches is because of their ability to handle a large amount of data related to the patients with accuracy, reliability in a short span of time. However, the practitioners may take time in analyzing and generating reports. In this paper, we have proposed a Deep Neural Network-based classification model for Parkinson’s disease. Our proposed method is one such good example giving faster and more accurate results for the classification of Parkinson’s disease patients with excellent accuracy of 94.87%. Based on the attributes of the dataset of the patient, the model can be used for the identification of Parkinsonism's. We have also compared the results with other existing approaches like Linear Discriminant Analysis, Support Vector Machine, K-Nearest Neighbor, Decision Tree, Classification and Regression Trees, Random Forest, Linear Regression, Logistic Regression, Multi-Layer Perceptron, and Naive Bayes.


Author(s):  
Khairul Anam ◽  
Adel Al-Jumaily

Myoelectric pattern recognition (MPR) is used to detect user’s intention to achieve a smooth interaction between human and machine. The performance of MPR is influenced by the features extracted and the classifier employed. A kernel extreme learning machine especially radial basis function extreme learning machine (RBF-ELM) has emerged as one of the potential classifiers for MPR. However, RBF-ELM should be optimized to work efficiently. This paper proposed an optimization of RBF-ELM parameters using hybridization of particle swarm optimization (PSO) and a wavelet function. These proposed systems are employed to classify finger movements on the amputees and able-bodied subjects using electromyography signals. The experimental results show that the accuracy of the optimized RBF-ELM is 95.71% and 94.27% in the healthy subjects and the amputees, respectively. Meanwhile, the optimization using PSO only attained the average accuracy of 95.53 %, and 92.55 %, on the healthy subjects and the amputees, respectively. The experimental results also show that SW-RBF-ELM achieved the accuracy that is better than other well-known classifiers such as support vector machine (SVM), linear discriminant analysis (LDA) and k-nearest neighbor (kNN).


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