scholarly journals Pediatric Endoscopy, Update 2020

2019 ◽  
Vol 9 (23) ◽  
pp. 5036 ◽  
Author(s):  
Dagmar Schreiber-Dietrich ◽  
Michael Hocke ◽  
Barbara Braden ◽  
Silvia Carrara ◽  
Uwe Gottschalk ◽  
...  
Keyword(s):  
Multidisciplinary Approach ◽  
Pediatric Patients ◽  
Current Knowledge ◽  
High Volume ◽  
Optimal Management ◽  
High Quality ◽  
Endoscopic Procedures ◽  
Endoscopic Techniques ◽  
Pediatric Endoscopy ◽  
Knowledge And Practice

Optimal management of pediatric endoscopy requires a multidisciplinary approach. In most hospitals, endoscopy in pediatric patients is performed by conventional gastroenterologists and only a few centers have specialized pediatric gastroenterologists. This is due to the fact that the number of pediatric gastroenterologists is limited and not all of them are experienced in endoscopic techniques. However, there are also some pediatric centers offering a high-quality and high-volume endoscopy service provided by very experienced pediatric gastroenterologists. Up to now, the literature on pediatric endoscopy is rather sparse. In this article, we describe current knowledge and practice of endoscopic procedures in pediatric patients, which should be relevant for both the adult and pediatric gastroenterologists.

scholarly journals Anorectal and Genital Mucosal Melanoma: Diagnostic Challenges, Current Knowledge and Therapeutic Opportunities of Rare Melanomas

Biomedicines ◽  
2022 ◽  
Vol 10 (1) ◽  
pp. 150
Author(s):  
Margaret Ottaviano ◽  
Emilio Francesco Giunta ◽  
Laura Marandino ◽  
Marianna Tortora ◽  
Laura Attademo ◽  
...  
Keyword(s):  
Management Strategy ◽  
Multidisciplinary Approach ◽  
Current Knowledge ◽  
Treatment Options ◽  
Mucosal Melanoma ◽  
Optimal Management ◽  
Research Needs ◽  
Tumor Characterization ◽  
Therapeutic Value ◽  
Poor Outcomes

Mucosal melanomas (MM) are rare tumors, being less than 2% of all diagnosed melanomas, comprising a variegated group of malignancies arising from melanocytes in virtually all mucosal epithelia, even if more frequently found in oral and sino-nasal cavities, ano-rectum and female genitalia (vulva and vagina). To date, there is no consensus about the optimal management strategy of MM. Furthermore, the clinical rationale of molecular tumor characterization regarding BRAF, KIT or NRAS, as well as the therapeutic value of immunotherapy, chemotherapy and targeted therapy, has not yet been deeply explored and clearly established in MM. In this overview, focused on anorectal and genital MM as models of rare melanomas deserving of a multidisciplinary approach, we highlight the need of referring these patients to centers with experts in melanoma, anorectal and uro-genital cancers treatments. Taking into account the rarity, the poor outcomes and the lack of effective treatment options for MM, tailored research needs to be promptly promoted.

Complicated grief knowledge and practice: a qualitative study of general practitioners in Ireland

2021 ◽  
pp. 1-6
Author(s):  
Abiola Muhammed ◽  
Anne Dodd ◽  
Suzanne Guerin ◽  
Susan Delaney ◽  
Philip Dodd
Keyword(s):  
Qualitative Study ◽  
General Practitioners ◽  
Current Knowledge ◽  
Complicated Grief ◽  
Phenomenological Approach ◽  
Structured Interviews ◽  
Relevant Research ◽  
Loved One ◽  
Knowledge And Practice ◽  
Purposive Sample

Objective: Complicated grief is a debilitating condition that individuals may experience after losing a loved one. General practitioners (GPs) are well positioned to provide patients with support for grief-related issues. Traditionally, Irish GPs play an important role in providing patients with emotional support regarding bereavement. However, GPs have commonly reported not being aptly trained to respond to bereavement-related issues. This study explores GPs’ current knowledge of and practice regarding complicated grief. Methods: A qualitative study adopting a phenomenological approach to explore the experiences of GPs on this issue. Semi-structured interviews were carried out with a purposive sample of nine GPs (five men and four women) in Ireland. Potential participants were contacted via email and phone. Interviews were audio-recorded, transcribed and analysed using Braun & Clarke’s (2006) model of thematic analysis. Results: GPs had limited awareness of the concept of complicated grief and were unfamiliar with relevant research. They also reported that their training was either non-existent or outdated. GPs formed their own knowledge of grief-related issues based on their intuition and experiences. For these reasons, there was not one agreed method of how to respond to grief-related issues reported by patients, though participants recognised the need for intervention, onward referral and review. Conclusions: The research highlighted that GPs felt they required training in complicated grief so that they would be better able to identify and respond to complicated grief.

Pyometra Management Practices in the High Quality, High Volume Spay-Neuter Environment

2021 ◽  
Vol 42 ◽  
pp. 100499
Author(s):  
Ashlee J. McCallin ◽  
Veronica A. Hough ◽  
Rachael E. Kreisler
Keyword(s):  
Management Practices ◽  
High Volume ◽  
High Quality

scholarly journals Management of chyle leaks following esophageal resection: a systematic review

2021 ◽  
Author(s):  
Robert Power ◽  
Philip Smyth ◽  
Noel E Donlon ◽  
Timothy Nugent ◽  
Claire L Donohoe ◽  
...  
Keyword(s):  
Thoracic Duct ◽  
Prospective Studies ◽  
Case Series ◽  
Esophageal Resection ◽  
Evidence Base ◽  
Treatment Modalities ◽  
Optimal Management ◽  
Retrospective Case ◽  
High Quality ◽  
Chyle Leakage

Summary Background Chyle leakage is an uncommon but potentially life-threatening complication following esophageal resections. The optimal management strategy is not clear, with a limited evidence base. Methods Searches were conducted up to 31 December 2020 on MEDLINE, Embase, and Web of Science for randomized trials or retrospective studies that evaluated the management of chyle leakage following esophageal resection. Two authors independently screened studies, extracted data, and assessed for bias. The protocol was prospectively registered on PROSPERO (CRD: 42021224895) and reported in accordance with preferred reporting items for systematic reviews and meta-analyses guidelines. Results A total of 530 citations were reviewed. Twenty-five studies, totaling 1016 patients met the inclusion criteria, including two low-quality clinical trials and 23 retrospective case series. Heterogeneity of study design and outcomes prevented meta-analysis. The overall incidence of chyle leak/fistula was 3.2%. Eighteen studies describe management of chyle leaks conservatively, 17 by surgical ligation of the thoracic duct, 5 by pleurodesis, and 6 described percutaneous lymphangiography with thoracic duct embolization or disruption. Conclusions The evidence base for optimal management of chyle leakage postesophagectomy is lacking, which may be related to its low incidence. There is a paucity of high-quality prospective studies directly comparing treatment modalities, but there is some low-certainty evidence that percutaneous approaches have reduced morbidity but lower efficacy compared with surgery. Further high-quality, prospective studies that compare interventions at different levels of severity are needed to determine the optimal approach to treatment.

scholarly journals The use of questionnaires for acquiring information on public perception of natural hazards and risk mitigation – a review of current knowledge and practice

2009 ◽  
Vol 9 (4) ◽  
pp. 1307-1325 ◽  
Author(s):  
D. K. Bird
Keyword(s):  
Natural Hazards ◽  
Public Perception ◽  
Current Knowledge ◽  
Risk Mitigation ◽  
Mode Of Delivery ◽  
Sampling Technique ◽  
Future Research ◽  
Delivery Mode ◽  
Management Procedures ◽  
Knowledge And Practice

Abstract. Questionnaires are popular and fundamental tools for acquiring information on public knowledge and perception of natural hazards. Questionnaires can provide valuable information to emergency management agencies for developing risk management procedures. Although many natural hazards researchers describe results generated from questionnaires, few explain the techniques used for their development and implementation. Methodological detail should include, as a minimum, response format (open/closed questions), mode of delivery, sampling technique, response rate and access to the questionnaire to allow reproduction of or comparison with similar studies. This article reviews current knowledge and practice for developing and implementing questionnaires. Key features include questionnaire design, delivery mode, sampling techniques and data analysis. In order to illustrate these aspects, a case study examines methods chosen for the development and implementation of questionnaires used to obtain information on knowledge and perception of volcanic hazards in a tourist region in southern Iceland. Face-to-face interviews highlighted certain issues with respect to question structure and sequence. Recommendations are made to overcome these problems before the questionnaires are applied in future research projects. In conclusion, basic steps that should be disclosed in the literature are provided as a checklist to ensure that reliable, replicable and valid results are produced from questionnaire based hazard knowledge and risk perception research.

scholarly journals LINC-39. PERFORMANCE STATUS OF PEDIATRIC PATIENTS WITH CENTRAL NERVOUS SYSTEM TUMORS TREATED IN MEXICO, A SINGLE-CENTER EXPERIENCE

2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii385-iii386
Author(s):  
Claudia Madrigal-Avila ◽  
Alfonso Perez-Bañuelos ◽  
Rafael Ruvalcaba-Sanchez ◽  
Lourdes Vega-Vega ◽  
Gabriela Escamilla-Asiain
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Multidisciplinary Approach ◽  
Pediatric Patients ◽  
Performance Status ◽  
Retrospective Chart Review ◽  
Cns Tumors ◽  
Surgical Morbidity ◽  
Tertiary Center

Abstract BACKGROUND Central nervous system (CNS) tumors are the most common solid neoplasms in the pediatric age, they comprise about a quarter of all cancers at this age. Little is known about the specific epidemiology of this group in Mexico and there are no reports of results focused on the Performance Status of patients who are treated in a multidisciplinary setting. OBJECTIVE To describe the Performance Status of CNS pediatric patients after being treated with a multidisciplinary approach in a tertiary center. METHODS We report a retrospective chart review of all pediatric patients who presented to the Neuro-Oncology Clinic at Teleton Pediatric Oncology Hospital in Queretaro, Mexico, from December 2014 to January 2020. We analyzed age, gender, the extent of surgical resection and histopathology. Performance Status was assessed using ECOG and Karnofsky/Lansky scores during every patient’s last follow-up visit. RESULTS A total of 56 patients were treated, epidemiology and histopathology variants are similar to those described in the international literature. With a median follow-up of 33 months, 35 patients are alive (62.5%), 28 of them (74.2%) have an excellent Performance Status (ECOG score 0 or Lansky/Karnofsky ≥ 90), 5 (14.2%) scored ECOG 1–2 and only 4 (11.4%) scored ECOG 3–4. CONCLUSIONS A multidisciplinary approach with a focus on Performance Status and the potential for neurological recovery is essential in the management of pediatric patients with CNS tumors. Efforts should be aimed at reducing post-surgical morbidity and early rehabilitation to reintegrate patients into society in the long term.

Obtaining High-Quality Blood Specimens for Downstream Applications: A Review of Current Knowledge and Best Practices

2018 ◽  
Vol 16 (6) ◽  
pp. 411-418 ◽  
Author(s):  
Qiyuan Li ◽  
Xian Wang ◽  
Xue Li ◽  
Xuheng He ◽  
Qian Wan ◽  
...  
Keyword(s):  
Best Practices ◽  
Current Knowledge ◽  
High Quality ◽  
Blood Specimens

Vision-based assessment of viability of acorns using sections of their cotyledons during automated scarification procedure

2018 ◽  
Vol 14 (1) ◽  
Author(s):  
Mirosław Jabłoński ◽  
Ryszard Tadeusiewicz ◽  
Adam Piłat ◽  
Józef Walczyk ◽  
Paweł Tylek ◽  
...  
Keyword(s):  
Computer Vision ◽  
Color Image ◽  
High Volume ◽  
The Other ◽  
Assessment Criteria ◽  
High Quality ◽  
Overall Design

Abstract The goal of the research described in the article was to develop the device for the automatic scarification of acorns and computer vision-based assessment of their viability. The color image of the intersection of the tissue of cotyledons was selected as a key feature for separating healthy seeds from the spoiled ones. Because the device is being designed for the diagnosis of high volume of seeds aiming at producing high-quality seedlings, several assessment criteria of the overall design of the automaton are being assessed. The basic one is the overall accuracy of viability recognition. The other refers to particular functions implemented in the model of the device being described.

COVID-19 in pediatrics: The current knowledge and practice

2021 ◽  
Vol 21 ◽  
Author(s):  
Esmaeil Mehraeen ◽  
Shahram Oliaei ◽  
SeyedAhmad SeyedAlinaghi ◽  
Amirali Karimi ◽  
Pegah Mirzapour ◽  
...  
Keyword(s):  
Systematic Review ◽  
Current Knowledge ◽  
Systemic Disease ◽  
Severe Disease ◽  
Reliability And Validity ◽  
Current Evidence ◽  
Original Research ◽  
Consensus Statements ◽  
Knowledge And Practice ◽  
Novel Coronavirus

Introduction: SARS-CoV-2 is the novel coronavirus that causes severe acute respiratory syndrome and could afflict individuals from all walks of life. Children are usually asymptomatic or represent non-specific mild to moderate symptoms; therefore, they often remain undiagnosed and could be potential reservoirs and silent carriers of the virus. Despite the global attention to COVID-19 and its importance in public health, some clinical and paraclinical aspects of this disease in children are still unclear. Thus, we conducted a comprehensive systematic review of available literature to reflect on the current knowledge and practice of the disease among children. Methods: This study was a systematic review of current evidence conducted in October 2020. We performed a systematic search using the keywords in online databases. The investigation adheres to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist to ensure the reliability and validity of extracted literature and results. Results: We selected and reviewed 23 most related studies out of 1744 identified paper in an initial online search based on the inclusion and exclusion criteria of the present review; of whom, 13 were original research studies, and 10 were a letter to the editors, commentaries, viewpoints, consensus statements, and perspectives. Although due to the origin of the current pandemic, China was the country with the most publications (14 articles), data from several countries have beenincluded in this review. Conclusion: COVID-19 can also affect children and cause systemic disease with several internal organ involvements. However, the prevalence, severity, and diversity of the symptoms in children are less than in adults. Cough and fever appear to be some of the most common symptoms, followed by other symptoms such as gastrointestinal manifestations. Comorbidities increase the risk of severe COVID-19 in children, and those without underlying conditions are very unlikely to suffer from severe disease. Mental health issues such as anxiety and depression due to the isolated situation caused by pandemics are common findings in children of early ages and should be seriously considered in current practice.

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