scholarly journals Variation of Particle-Induced Oxidative Potential of PM2.5 in Xinjiang, NW-China

Atmosphere ◽  
2021 ◽  
Vol 12 (8) ◽  
pp. 1028
Author(s):  
Juqin An ◽  
Dilnurt Talifu ◽  
Xiang Ding ◽  
Longyi Shao ◽  
Xinming Wang ◽  
...  
Keyword(s):  
Dna Damage ◽  
Plasmid Dna ◽  
Assessment Method ◽  
Water Soluble ◽  
Back Trajectory ◽  
Taklimakan Desert ◽  
Heating Period ◽  
Oxidative Potential ◽  
The North ◽  
Soluble Fractions

In order to evaluate the toxicity of PM2.5 in the Dushanzi area, PM2.5 samples were collected from December 2015 to July 2016, and a plasmid DNA damage assessment method was used to analyze the variation in the oxidative damage ability and its relationship with sampling conditions and toxic components (polycyclic aromatic hydrocarbons, and heavy metals) loaded on the surface of PM2.5. The results showed that the TD30 values (toxic dosage of PM2.5 causing 30% of plasmid DNA damage) of both the whole samples and the water-soluble fractions were lower during the heating period (369 μg/mL and 536 μg/mL, respectively), but higher in the dust period and non-heating period (681 μg/mL and 498 μg/mL, respectively; and 804 μg/mL and 847 μg/mL, respectively). Studies on the effect of meteorological parameters showed an increasing trend in TD30 values for the whole samples and the water-soluble fractions as relative humidity, temperature and wind speed decrease. TD30 values for the whole samples and the water-soluble fractions were negatively correlated with Flu (r = −0.690,r = −0.668; p < 0.05), Flt (r =−0.671, r = −0.760; p < 0.05), BaP (r = −0.672, r = −0.725; p < 0.05), IcdP (r = −0.694, r = −0.740; p < 0.05), Pyr (r = −0.727, r = −0.768; p < 0.01) and BghiP (r = −0.874, r = −0.845; p < 0.01) during the heating period, while As (r = 0.792, r = 0.749; p < 0.05) and Sr (r = 0.776, r = 0.754; p < 0.05) during the dust period showed significant positive correlation. In addition, the TD30 values of PM2.5 collected during sand blowing weather was the highest (1458 μg/mL and 1750 μg/mL), while the average TD30 value of PM2.5 collected on hazy days were the lowest (419.8 μg/mL and 488.6 μg/mL). Particles collected on the first day after snowfall showed a lower oxidizing capacity (676 μg/mL and 1330 μg/mL). The characteristic TD30 values combined with back trajectory analysis indicated that hazy days were heavily influenced by air masses originating from the southern continent and local emissions, whereas the sand blowing weather came from the north of the Taklimakan Desert.

Influence of Saharan dust outbreaks and carbon content on oxidative potential of water-soluble fractions of PM2.5 and PM10

2017 ◽  
Vol 163 ◽  
pp. 1-8 ◽  
Author(s):  
Daniela Chirizzi ◽  
Daniela Cesari ◽  
Maria Rachele Guascito ◽  
Adelaide Dinoi ◽  
Livia Giotta ◽  
...  
Keyword(s):  
Carbon Content ◽  
Water Soluble ◽  
Saharan Dust ◽  
Oxidative Potential ◽  
Pm2.5 And Pm10 ◽  
Soluble Fractions

scholarly journals Water-Soluble Ions in Atmospheric Aerosol Measured in a Semi-Arid and Chemical-Industrialized City, Northwest China

Atmosphere ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 456
Author(s):  
Huimin Jiang ◽  
Zhongqin Li ◽  
Feiteng Wang ◽  
Xi Zhou ◽  
Fanglong Wang ◽  
...  
Keyword(s):  
Sulfur Oxidation ◽  
Northwest China ◽  
Water Soluble ◽  
Heterogeneous Reactions ◽  
Anthropogenic Source ◽  
Heating Period ◽  
Qinghai Province ◽  
Soluble Ions ◽  
Water Soluble Ions ◽  
Semi Arid

We investigated water-soluble ions (WSIs) of aerosol samples collected from 2016 to 2017 in Lanzhou, a typical semi-arid and chemical-industrialized city in Northwest China. WSIs concentration was higher in the heating period (35.68 ± 19.17 μg/m3) and lower in the non-heating period (12.45 ± 4.21 μg/m3). NO3−, SO42−, NH4+ and Ca2+ were dominant WSIs. The concentration of SO42− has decreased in recent years, while the NO3− level was increasing. WSIs concentration was affected by meteorological factors. The sulfur oxidation and nitrogen oxidation ratios (SOR and NOR) exceeded 0.1, inferring the vital contribution of secondary transformation. Meanwhile higher O3 concentration and temperature promoted the homogeneous reaction of SO2. Lower temperature and high relative humidity (RH) were more suitable for heterogeneous reactions of NO2. Three-phase cluster analysis illustrated that the anthropogenic source ions and natural source ions were dominant WSIs during the heating and non-heating periods, respectively. The backward trajectory analysis and the potential source contribution function model indicated that Lanzhou was strongly influenced by the Hexi Corridor, northeastern Qinghai–Tibetan Plateau, northern Qinghai province, Inner Mongolia Plateau and its surrounding cities. This research will improve our understanding of the air quality and pollutant sources in the industrial environment.

scholarly journals Genotoxic and oxidative effect of duloxetine on mouse brain and liver tissues

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Isela Álvarez-González ◽  
Scarlett Camacho-Cantera ◽  
Patricia Gómez-González ◽  
Michael J. Rendón Barrón ◽  
José A. Morales-González ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Dna Damage ◽  
Mouse Brain ◽  
Control Level ◽  
Dna Oxidation ◽  
Methyl Methanesulfonate ◽  
Control Group ◽  
Oxidative Potential ◽  
The Brain ◽  
Oxidative Effect

AbstractWe evaluated the duloxetine DNA damaging capacity utilizing the comet assay applied to mouse brain and liver cells, as well as its DNA, lipid, protein, and nitric oxide oxidative potential in the same cells. A kinetic time/dose strategy showed the effect of 2, 20, and 200 mg/kg of the drug administered intraperitoneally once in comparison with a control and a methyl methanesulfonate group. Each parameter was evaluated at 3, 9, 15, and 21 h postadministration in five mice per group, except for the DNA oxidation that was examined only at 9 h postadministration. Results showed a significant DNA damage mainly at 9 h postexposure in both organs. In the brain, with 20 and 200 mg/kg we found 50 and 80% increase over the control group (p ≤ 0.05), in the liver, the increase of 2, 20, and 200 mg/kg of duloxetine was 50, 80, and 135% in comparison with the control level (p ≤ 0.05). DNA, lipid, protein and nitric oxide oxidation increase was also observed in both organs. Our data established the DNA damaging capacity of duloxetine even with a dose from the therapeutic range (2 mg/kg), and suggest that this effect can be related with its oxidative potential.

scholarly journals Potential Source Areas for Atmospheric Lead Reaching Ny-Ålesund from 2010 to 2018

Atmosphere ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 388
Author(s):  
Andrea Bazzano ◽  
Stefano Bertinetti ◽  
Francisco Ardini ◽  
David Cappelletti ◽  
Marco Grotti
Keyword(s):  
North American ◽  
Enrichment Factors ◽  
Atmospheric Particulate Matter ◽  
Back Trajectory ◽  
Pb Isotope ◽  
Back Trajectories ◽  
Source Areas ◽  
The North ◽  
Central Asian ◽  
Pb Concentration

Lead content, enrichment factors, and isotopic composition (208Pb/206Pb and 207Pb/206Pb) measured in atmospheric particulate matter (PM10) samples collected for nine years at Ny-Ålesund (Svalbard islands, Norwegian Arctic) during spring and summer are presented and discussed. The possible source areas (PSA) for particulate inferred from Pb isotope ratio values were compared to cluster analysis of back-trajectories. Results show that anthropogenic Pb dominates over natural crustal Pb, with a recurring higher influence in spring, compared to summer. Crustal Pb accounted for 5–16% of the measured Pb concentration. Anthropogenic Pb was affected by (i) a Central Asian PSA with Pb isotope signature compatible with ores smelted in the Rudny Altai region, at the Russian and Kazakhstan border, which accounted for 85% of the anthropogenic Pb concentration, and (ii) a weaker North American PSA, contributing for the remaining 15%. Central Asian PSA exerted an influence on 71–86% of spring samples, without any significant interannual variation. On the contrary, 59–87% of summer samples were influenced by the North American PSA, with higher contributions during 2015 and 2018. Back-trajectory analysis agreed on the seasonal difference in PSA and highlighted a possible increased influence for North American air masses during summer 2010 and 2018, but not for summer 2015.

scholarly journals Inhibition of γ-Radiation Induced DNA Damage in Plasmid pBR322 by TMG, a Water-soluble Derivative of Vitamin E

2002 ◽  
Vol 43 (2) ◽  
pp. 153-153 ◽  
Author(s):  
REMA RAJAGOPALAN ◽  
KHALIDA WANI ◽  
NAGARAJ G. HUILGOL ◽  
TSUTOMU V. KAGIYA ◽  
CHERUPALLY K. KRISHNAN NAIR
Keyword(s):  
Dna Damage ◽  
Vitamin E ◽  
Water Soluble ◽  
Plasmid Pbr322 ◽  
Γ Radiation ◽  
Radiation Induced

Plasmid DNA damage caused by stibine and trimethylstibine

2004 ◽  
Vol 194 (1) ◽  
pp. 41-48 ◽  
Author(s):  
Paul Andrewes ◽  
Kirk T Kitchin ◽  
Kathleen Wallace
Keyword(s):  
Dna Damage ◽  
Plasmid Dna

Explosion Recurrence Modelling

2004 ◽  
Author(s):  
Sirous F. Yasseri ◽  
Jake Prager
Keyword(s):  
Risk Assessment ◽  
Goodness Of Fit ◽  
Residential Buildings ◽  
Limit State ◽  
Life Time ◽  
Assessment Method ◽  
The North ◽  
Offshore Installations ◽  
Risk Assessment Method ◽  
Explosion Load

This paper describes a recurrence law for explosions. The proposed recurrence law fits quite well to the historic explosion data in residential buildings as well as to the data on offshore installations in the North Sea. Generally quantified explosion risk assessment is performed for offshore installations, since it is believed historic data does not correspond to a specific installation and it may not be appropriate for use in performance based explosion engineering, which may in itself require realistic load description of explosion recurrence. The goodness-of-fit of the model for explosion occurrence data obtained using the quantified risk assessment method is also discussed. The paper then introduces the concept of performance-based design, which is an attempt to design structures with predictable performance under explosion loading. Performance objectives such as life safety, collapse prevention, or immediate resumption of operation are used to define the state of an installation following a design explosion. The recurrence law is then used to associate a level of explosion load to each limit state using a desirable level of probability of exceedance during the installations life time.

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