scholarly journals SUNCT/SUNA in Pediatric Age: A Review of Pathophysiology and Therapeutic Options

2021 ◽  
Vol 11 (9) ◽  
pp. 1252
Author(s):  
Carlo Alberto Cesaroni ◽  
Jacopo Pruccoli ◽  
Luca Bergonzini ◽  
Giuseppe Quatrosi ◽  
Luigi Vetri ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Negative Impact ◽  
Young Patients ◽  
Therapeutic Options ◽  
Non Invasive ◽  
Cranial Autonomic Symptoms ◽  
Developmental Age ◽  
The One

The International Classification of Headache Disorders, 3rd edition (ICHD3) defines Short-lasting Unilateral Neuralgiform Headache Attacks (SUNHA) as attacks of moderate or severe, strictly unilateral head pain lasting from seconds to minutes, occurring at least once a day and usually associated with prominent lacrimation and redness of the ipsilateral eye. Two subtypes of SUNHA are identified: Short-lasting Unilateral Neuralgiform headache attacks with Conjunctival injection and Tearing (SUNCT) and Short-lasting Unilateral Neuralgiform headache attacks with cranial Autonomic symptoms (SUNA). These pathologies are infrequent in children and difficult to diagnose. The authors reviewed the existing literature on SUNCT and SUNA, especially in the developmental age, which describes the pathophysiology in detail and focuses on the therapeutic options available to date. SUNHA-type headaches must be considered on the one hand, for the possibility of the onset of forms secondary to underlying pathologies even of a neoplastic nature, and on the other hand, for the negative impact they can have on an individual’s quality of life, particularly in young patients. Until now, published cases suggest that no chronic variants occur in childhood and adolescents. In light of this evidence, the authors offer a review that may serve as a source to be drawn upon in the implementation of suitable treatments in children and adolescents suffering from these headaches, focusing on therapies that are non-invasive and as risk-free as possible for pediatric patients.

Pathophysiology, Classification, Clinical Diagnosis and Treatment of Primary Epiretinal Membrane

2018 ◽  
pp. 262-267
Keyword(s):  
Clinical Examination ◽  
Epiretinal Membrane ◽  
Posterior Vitreous Detachment ◽  
Internal Limiting Membrane ◽  
Non Invasive ◽  
Diagnosis And Classification ◽  
Pars Plana ◽  
Vitreomacular Interface

Epiretinal membrane (ERM), also known as macular pucker, premacular fibroplasia, premacular gliosis, or cellophane maculopathy is a common vitreoretinal interface pathology that can result in mild to moderate visual impairment with an impact on the quality of life. ERM can be classified as primary “idiopathic” or secondary. Most ERMs occur in individuals older than 50 years, and the prevalence of ERM increases as age increases. The pathological mechanisms are not entirely known, however, the posterior vitreous detachment is thought to be key. Diagnosis and classification of ERM are based on clinical examination findings. However, high resolution spectral domain-optic coherence tomographies (SD-OCTs) have proven to be more sensitive than clinical examination for the diagnosis of numerous disorders of the vitreomacular interface, including ERM. SD-OCTs enable the pre-and postoperative comparison of macular structures in a non-invasive examination. In treatment, surgical intervention entails pars plana vitrectomy with ERM removal with or without internal limiting membrane (ILM) removal. Good visual recovery was present in most patients after surgery.

scholarly journals Quality of Life in Patients with Psoriasis Seen in the Department of Dermatology, Antananarivo, Madagascar

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Fandresena Arilala Sendrasoa ◽  
Naina Harinjara Razanakoto ◽  
Volatantely Ratovonjanahary ◽  
Onivola Raharolahy ◽  
Irina Mamisoa Ranaivo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Negative Impact ◽  
Young Patients ◽  
The Body ◽  
University Hospital ◽  
Medical Decision ◽  
Cross Sectional ◽  
The Difference ◽  
The Impact

Background. Psoriasis is a chronic, inflammatory, and multifactorial dermatosis that impairs quality of life (QoL). Health-related QoL has become an important element in medical decision-making along with the effectiveness and the harmlessness of the treatments. Objective. To assess the impact of psoriasis in the QoL of patients with psoriasis by using the DLQI scales. Methods. A cross-sectional study from January to June 2018 was conducted in the Department of Dermatology of the University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar, including patients more than 18 years old with mild to severe psoriasis. The severity of psoriasis was assessed using the “Psoriasis Area and Severity Index (PASI)”. QoL of patients with psoriasis was evaluated by using the DLQI scales. Results. 80 patients were included, their mean age was 36.5 years, and the male to female was 1.5 : 1. The mean DLQI score was 13.8. Symptoms, feelings, and psychic were the most altered dimensions. QoL was impaired in young patients, single, having medium level education. Even though patients with disease duration more than 5 years had higher DLQI score than other patients, the difference was not statistically significant (p=0.36). Furthermore, the clinical presentation of psoriasis did not influence the patient’s QoL (p=0.73). Patients with nail involvement had QoL impaired but the difference with another localization was not statistically significant (p=0.2). The quality of life was influenced by body area involved. The higher the body surface area involved, the more QoL is impaired (p=0.002). Furthermore, the higher the PASI, the more QoL is altered (p=0.002). Conclusion. Psoriasis has a negative impact in the quality of life in Malagasy patients with psoriasis, especially in younger and single patients. Worse quality of life is correlated to severity of psoriasis.

Quality of life assessment in children before and after a successful ablation for supraventricular tachycardia

2020 ◽  
Vol 30 (3) ◽  
pp. 413-417 ◽  
Author(s):  
M Cecilia Gonzalez Corcia ◽  
Laura Peters ◽  
Thierry Sluysmans ◽  
Stephane Moniotte ◽  
Karlien Carbonez ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Negative Impact ◽  
Accessory Pathway ◽  
Young Patients ◽  
Life Assessment ◽  
Percutaneous Ablation ◽  
Supraventricular Arrhythmias ◽  
Ectopic Atrial Tachycardia ◽  
Before And After

ABSTRACTBackground and Objectives:Young patients suffering from rhythm disorders have a negative impact in their quality of life. In recent years, ablation has become the first-line therapy for supraventricular arrhythmias in children. In the light of the current expertise and advancement in the field, we decided to evaluate the quality of life in young patients with supraventricular arrhythmias before and after a percutaneous ablation procedure.Methods:The prospective cohort consisted of patients <18 years with structurally normal hearts and non-pre-excited supraventricular arrhythmias, who had an ablation in our centre from 2013 to 2018. The cohort was evaluated with the PedsQL™ 4.0 Generic Core Scales self-questionnaire prior to and post-ablation.Results:The final cohort included 88 patients consisted of 52 males (59%), with a mean age at ablation of 12.5 ± 3.3 years. Forty-two patients (48%) had a retrograde-only accessory pathway mediating the tachycardia, 38 (43%) had atrio-ventricular nodal re-entrant tachycardia, 7 (8%) had ectopic atrial tachycardia, and 1 (1%) had atrial flutter. The main reason for an ablation was the patient’s choice in 53%. There were no severe complications. Comparison between the baseline and post-ablation assessments showed that patients reported significant improvement in the scores for physical health, emotional and social functioning, as well as in the total scores.Conclusions:The present study demonstrates that the successful treatment of supraventricular arrhythmias by means of an ablation results in a significant improvement in the quality of self-reported life scores in young patients.

scholarly journals Mastectomy versus conservative surgical treatment: the impact on the quality of life of women with breast cancer

2010 ◽  
Vol 10 (1) ◽  
pp. 51-57 ◽  
Author(s):  
Daniela Francescato Veiga ◽  
Fabíola Soares Moreira Campos ◽  
Leda Marques Ribeiro ◽  
Ivanildo Archangelo Junior ◽  
Joel Veiga Filho ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Physical Functioning ◽  
Negative Impact ◽  
Young Patients ◽  
Conservative Surgery ◽  
Sf 36 ◽  
Significant Difference ◽  
The Impact

OBJECTIVES: to compare the impact of mastectomy and conservative surgery on the quality of life of patients with breast cancer. METHODS: an assessment was made of the quality of life of patients undergoing mastectomy or segmentary mastectomy, at the Pouso Alegre Clinical Hospital, in the Brazilian State of Minas Gerais, using SF-36. The patients were grouped by age (<50 years and >50 years) and years of schooling (<8 years and >8 years). The Mann-Whitney test was used to compare the groups with regard to the age and schooling domains of SF-36. RESULTS: a significant difference between the two groups was found in the domains of "physical functioning" (p=0.04) and "pain" (p=0.01): with the patients undergoing a mastectomy registering the worst scores. Young patients who had undergone a mastectomy displayed the worst quality of life in terms of "physical functioning" (p=0.03), "pain" (p=0.01) and "social functioning" (p=0.01); those undergoing conservative surgery aged over 50 years scored worst on "role emotional" (p=0.05). Patients undergoing a mastectomy with lower levels of schooling scored lower in "physical functioning" (p=0.01), "role physical" (p=0.05) and "pain" (p=0.05). Among those who had attended school for more than eight years, those having undergone a mastectomy scored less in the "pain" domain (p=0.04). CONCLUSIONS: patients who had undergone a mastectomy had worse results in the physical component of the evaluation of quality of life and this negative impact was more strongly felt among younger patients and those with lower levels of schooling.

scholarly journals A Warning Call for Fertility Preservation Methods for Women Undergoing Gonadotoxic Cancer Treatment

Medicina ◽  
2021 ◽  
Vol 57 (12) ◽  
pp. 1340
Author(s):  
Claudia Mehedintu ◽  
Francesca Frincu ◽  
Andreea Carp-Veliscu ◽  
Ramona Barac ◽  
Dumitru-Cristinel Badiu ◽  
...  
Keyword(s):  
Cancer Treatment ◽  
Fertility Preservation ◽  
Ovarian Reserve ◽  
Negative Impact ◽  
Future Fertility ◽  
Negative Effect ◽  
The One

Malignant hematological conditions have recognized an increased incidence and require aggressive treatments. Targeted chemotherapy, accompanied or not by radiotherapy, raises the chance of defeating the disease, yet cancer protocols often associate long-term gonadal consequences, for instance, diminished or damaged ovarian reserve. The negative effect is directly proportional to the types, doses, time of administration of chemotherapy, and irradiation. Additionally, follicle damage depends on characteristics of the disease and patient, such as age, concomitant diseases, previous gynecological conditions, and ovarian reserve. Patients should be adequately informed when proceeding to gonadotoxic therapies; hence, fertility preservation should be eventually regarded as a first-intention procedure. This procedure is most beneficial when performed before the onset of cancer treatment, with the recommendation for embryos or oocytes’ cryopreservation. If not feasible or acceptable, several options can be available during or after the cancer treatment. Although not approved by medical practice, promising results after in vitro studies increase the chances of future patients to protect their fertility. This review aims to emphasize the mechanism of action and impact of chemotherapy, especially the one proven to be gonadotoxic, upon ovarian reserve and future fertility. Reduced fertility or infertility, as long-term consequences of chemotherapy and, particularly, following bone marrow transplantation, is often associated with a negative impact of recovery, social and personal life, as well as highly decreased quality of life.

scholarly journals O impacto na qualidade de vida dos portadores de úlceras vasculogênicas

2018 ◽  
Vol 86 (24) ◽  
Author(s):  
Maria Cristina Augusta Coelho ◽  
Sônia Regina Souza ◽  
Paulo César Alves ◽  
Denise Sória
Keyword(s):  
Quality Of Life ◽  
Quantitative Study ◽  
Nursing Care ◽  
Negative Impact ◽  
Physical Domain ◽  
The One ◽  
Microsoft Office

Objetivo: Analisar aspectos da qualidade de vida de portadores de úlceras vasculogênicas, a partir do instrumento WhoqolBref, e identificar o domínio de maior impacto para a qualidade de vida. Método: Trata-se de um estudo do tipo quantitativodescritivo, foi utilizado o WHOQOL-BREF, utilizando-se o Microsoft Office -Excel 2010 para a realização do cálculo dosescores e estatística descritiva do WHOQOL-bref. Resultados: Analisou-se os quatro domínios do Whoqol-Bref, o domíniofísico obteve menor pontuação, evidenciando que a dimensão física, foi a que obteve maior impacto negativo na qualidadede vida, sendo considerada a que mais afeta os portadores de úlceras vasculogênicas. Conclusão: O estudo evidenciou adimensão física sendo a que mais afeta a qualidade de vida dos portadores de úlceras vasculogênicas. Compreender sobrea qualidade de vida propicia estabelecer uma assistência integral.Palavras-chave: Enfermagem; Feridas; Cuidados de enfermagem. AbstractObjective: To analyze aspects of the quality of life of patients with vasculogenic ulcers, based on the Whoqol-Bref instrument,and to identify the domain with the greatest impact on the quality of life. Method: The WHOQOL-BREF was used as adescriptive quantitative study, using Microsoft Office -Excel 2010 for the calculation of the WHOQOL-bref scores anddescriptive statistics. Results: The four domains of the Whoqol-Bref were analyzed, the physical domain obtained a lowerscore, showing that the physical dimension was the one that had the greatest negative impact on the quality of life, beingconsidered the one that most affects the patients with vasculogenic ulcers. Conclusion: The study evidenced the physicaldimension being the one that most affects the quality of life of patients with vasculogenic ulcers. Understanding about thequality of life provides an integral assistance.Key words: Nursing; Wounds; Nursing care.

Cyber Physical direction of irrigated agriculture development 

2021 ◽  
Author(s):  
Anatoly Zeyliger ◽  
Olga Ermolaeva
Keyword(s):  
Natural Resources ◽  
Agricultural Production ◽  
Negative Impact ◽  
External Environment ◽  
Irrigated Agriculture ◽  
Agricultural Crops ◽  
The One ◽  
The Impact

&lt;p&gt;Until recently, new technologies introduced into irrigated agriculture were mainly aimed at developing one or several related control actions. However, the needs of society to increase the volume and improve the quality of agricultural products have led to significant qualitative changes in irrigated agriculture. The various robotic systems used for this have proven their effectiveness in the mechanization and automation of the irrigation process, as well as in the application of chemical fertilizers and chemical protection of agricultural crops from diseases and pests. This resulted in higher yields while lowering production costs.Nowadays, biotechnologies currently being developed and being introduced into irrigated agriculture, as well as systems for controlling and monitoring environmental impacts, are aimed at solving problems related to further increasing the efficiency of the use of natural resources, while minimizing the risks of negative impact on components and services of the environment.This is largely due to the impact of the rapid development of IC and sensor technologies aimed at creating production management systems based on the cyber-physical systems (CPS) paradigm. For this, there are using a holistic vision of the structure and cybernetic methods of management, artificial intelligence technologies, as well as digital platforms for integrating information flows between sub-subsystems of management, control, monitoring and decision support.In this context, the main difference between developed agricultural CPSs from the existing industrial agricultural systems focused on current economic efficiency lies in the plane of making agricultural production sustainable in the long term based on a balance between economic efficiency and the quality of natural resources used and services of the environment. From this point of view, irrigated agriculture focuses on the efficient use of natural resources, which are water, soil and air, as well as renewable and non-renewable (fossil) energy. At the same time, weather are considered as the impact of the external environment providing an irreplaceable source of water, heat and energy resources but with stochastic characteristics that are difficult to formalize. In connection with this diversity, a CPSs are built taking into account a complex compromise that takes into account many aspects of the negative impact of intensive agricultural production technologies on the qualitative and quantitative characteristics of these resources, not only in the place of their use, but also on the external environment beyond these limits. In this regard, water resources are one of the most important factors necessary, on the one hand, to impart long-term sustainability to irrigated agriculture, and on the one hand, as a factor that can lead in the near future to a significant decrease in fertility, as well as to a negative impact on the environmental services of the surrounding area. This contribution discusses some points of the development of an agricultural irrigation CPS&amp;#8217; subsystem aimed to monitor the soil moisture content at the root zone of the soil cover at the scale of irrigated agricultural crops and their relationship with industrial sprinkling technologies.Acknowledgments: The reported study was funded by RFBR, project number 19-29-05261 mk&lt;/p&gt;

scholarly journals Anxiety: a hidden element in dementia

2012 ◽  
Vol 18 (2) ◽  
pp. 119-128 ◽  
Author(s):  
Vellingiri Raja Badrakalimuthu ◽  
Andrew F. Tarbuck
Keyword(s):  
Quality Of Life ◽  
Cognitive Impairment ◽  
Anxiety Disorders ◽  
Old Age ◽  
Negative Impact ◽  
Poor Quality ◽  
Therapeutic Options ◽  
Prevalence Rates ◽  
People With Dementia

SummaryAnxiety has reported prevalence rates between 38 and 72% among people with dementia. It has a negative impact on cognitive impairment and is associated with agitation and poor quality of life. The presence of excessive anxiety can be difficult to establish in people with dementia, especially when expressive or receptive speech is impaired. Unfortunately, there is a lack of research on the treatment of anxiety in dementia, and also on the wider issue of the management of anxiety disorders in old age. We explore the prevalence, presentation and diagnosis of anxiety in dementia and discuss the therapeutic options available.

Quality of life, intellectual development and behavioural characteristics of single children in China: evidence from a 1980 survey in Changsha, Hunan Province

1985 ◽  
Vol 17 (2) ◽  
pp. 127-136 ◽  
Author(s):  
Dudley L. Poston ◽  
Mei-Yu Yu
Keyword(s):  
Quality Of Life ◽  
Intellectual Development ◽  
Negative Impact ◽  
The United States ◽  
Hunan Province ◽  
Social Scientists ◽  
Behavioural Characteristics ◽  
Children’S Behaviour ◽  
The One

SummaryThis paper reports the results of a June 1980 survey of 1069 children in Changsha, Hunan Province. The data have been unavailable previously either in Chinese or in English. In general, they suggest that comparisons of single children with children from multiple-child families in China regarding quality of life, intellectual development, and behavioural traits are similar to comparisons conducted in the United States and other western countries. As in many western studies, single children in China appear to have a better quality of life than children with siblings. Regarding intellectual development, single children in China perform better than those with siblings, a finding which is consonant with the family intactness model of Falbo. Single children in Changsha are little different from ones from multiple-child families on various aspects of behaviour, and are more co-operative and less hostile. These findings are the opposite of those of the Shanghai study, the other major analysis of single children in China; the Shanghai survey indicated that single children were not as well-behaved as those with siblings, a finding that caused some concern among Chinese social scientists. To the extent that the findings of the Changsha study, and not those of the Shanghai study, reflect the situation of single children in China, this could mean that the one-child family planning campaign may not be having a negative impact on children's behaviour.

scholarly journals Quality of Life in Pediatric Patients with Allergic Rhinitis treated at the Medical Clinic of Integrated Education – Unisul

2017 ◽  
Vol 21 (04) ◽  
pp. 371-376 ◽  
Author(s):  
Mariana Dziekanski ◽  
Taíse Marcelino
Keyword(s):  
Quality Of Life ◽  
Allergic Rhinitis ◽  
Pediatric Patients ◽  
Negative Impact ◽  
Common Disease ◽  
Life Questionnaire ◽  
Medical Clinic ◽  
Integrated Education ◽  
Nasal Symptoms

Introduction Allergic rhinitis is a common disease among children and adolescents, reaching up to 40% of the population. During childhood, it is usually underdiagnosed because it has nonspecific symptoms. It has a negative impact on quality of life and may predispose to comorbidities. The diagnosis is clinical and treatment aims prevention. Objective The objective of this study is to evaluate the quality of life in pediatric patients with allergic rhinitis. Methods This is an observational study with cross-sectional design. The population consisted of pediatric patients with allergic rhinitis treated at the Medical Clinic of Integrated Education (MCIE) – Universidade do Sul de Santa Catarina - Unisul, Tubarão, SC, Brazil. We collected data from March to June 2016 through the application of the Sociodemographic and Health Questionnaire, rhinitis module of the International Study of Asthma and Allergies in Childhood Questionnaire and the Rhinoconjunctivitis Quality of Life Questionnaire Modified. Results Out of the 69 respondents, 52.2% were boys with a mean age of 10.13 years old. The predominant education level of parents/guardians was incomplete second grade and average income level was two minimum wages. 81.2% said they had previous treatment for AR, 30.4% had asthma and 7.2% eczema. Incidence of patients smoking was absent and family (parents/guardians) smoking was 17.4%. March to July were the months of highest symptom occurrence, slightly disturbing daily activities. The mean value of severity was 51.9, nasal symptoms were the most uncomfortable, and nasal itchiness was the most cited. Conclusion Our results highlight that allergic symptoms negatively impact the life of people with allergic rhinitis, with a predominance of nasal symptoms, especially nasal itchy, representing a poor quality of life of the interviewed.

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