scholarly journals Nanomaterials Based Electrochemical Sensors for Serotonin Detection: A Review

Chemosensors ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 14
Author(s):  
Dorin Dăscălescu ◽  
Constantin Apetrei

The present review deals with the recent progress made in the field of the electrochemical detection of serotonin by means of electrochemical sensors based on various nanomaterials incorporated in the sensitive element. Due to the unique chemical and physical properties of these nanomaterials, it was possible to develop sensitive electrochemical sensors with excellent analytical performances, useful in the practice. The main electrochemical sensors used in serotonin detection are based on carbon electrodes modified with carbon nanotubes and various materials, such as benzofuran, polyalizarin red-S, poly(L-arginine), Nafion/Ni(OH)2, or graphene oxide, incorporating silver-silver selenite nanoparticles, as well as screen-printed electrodes modified with zinc oxide or aluminium oxide. Also, the review describes the nanocomposite sensors based on conductive polymers, tin oxide-tin sulphide, silver/polypyrole/copper oxide or a hybrid structure of cerium oxide-gold oxide nanofibers together with ruthenium oxide nanowires. The presentation focused on describing the sensitive materials, characterizing the sensors, the detection techniques, electroanalytical properties, validation and use of sensors in lab practice.

2012 ◽  
Vol 86 ◽  
pp. 40-50
Author(s):  
Sirinrath Sirivisoot ◽  
Thomas J. Webster

Although improvements have been made in implant design to increase bone formation and promote successful osseointegration using nanotechnology, the clinical diagnosis of early bone growth surrounding implants remains problematic. The development of a device allowing doctors to monitor the healing cascade and to diagnose potential infection or inflammation is necessary. Biological detection can be examined by the electrochemical analysis of electron transfer (or redox) reactions of extracellular matrix proteins involved in bone deposition and resorption. The use of nanomaterials as signal amplifiers in electrochemical sensors has greatly improved the sensitivity of detection. Nanotechnology-enabled electrochemical sensors that can be placed on the implant surface itself show promise as self-diagnosing devices in situ, possibly to detect new bone growth surrounding the implant and other cellular events to ensure implant success.


Ionics ◽  
2008 ◽  
Vol 15 (3) ◽  
pp. 377-383 ◽  
Author(s):  
C. Vedhi ◽  
G. Selvanathan ◽  
P. Arumugam ◽  
P. Manisankar

2019 ◽  
Vol 7 (37) ◽  
pp. 21168-21175 ◽  
Author(s):  
Junbo Liu ◽  
Lijing Zhang ◽  
Cheng Yang ◽  
Shengyang Tao

Multifunctional porous carbon materials prepared by laser irradiation on a phenolic resin were engineered into electrochemical sensors, microsupercapacitors, and Joule-heating devices.


2016 ◽  
Vol 663 ◽  
pp. 574-580 ◽  
Author(s):  
Yu Lim Kim ◽  
Yejin Ha ◽  
Nam-Suk Lee ◽  
Joo Gon Kim ◽  
Jeong Min Baik ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (21) ◽  
pp. 6566
Author(s):  
Yan-Ping Wei ◽  
Liang-Yuan Yao ◽  
Yi-Yong Wu ◽  
Xia Liu ◽  
Li-Hong Peng ◽  
...  

Acyclovir (ACV) is an effective and selective antiviral drug, and the study of its toxicology and the use of appropriate detection techniques to control its toxicity at safe levels are extremely important for medicine efforts and human health. This review discusses the mechanism driving ACV’s ability to inhibit viral coding, starting from its development and pharmacology. A comprehensive summary of the existing preparation methods and synthetic materials, such as 5-aminoimidazole-4-carboxamide, guanine and its derivatives, and other purine derivatives, is presented to elucidate the preparation of ACV in detail. In addition, it presents valuable analytical procedures for the toxicological studies of ACV, which are essential for human use and dosing. Analytical methods, including spectrophotometry, high performance liquid chromatography (HPLC), liquid chromatography/tandem mass spectrometry (LC-MS/MS), electrochemical sensors, molecularly imprinted polymers (MIPs), and flow injection–chemiluminescence (FI-CL) are also highlighted. A brief description of the characteristics of each of these methods is also presented. Finally, insight is provided for the development of ACV to drive further innovation of ACV in pharmaceutical applications. This review provides a comprehensive summary of the past life and future challenges of ACV.


Sensors ◽  
2019 ◽  
Vol 19 (9) ◽  
pp. 2037 ◽  
Author(s):  
Tavakolian-Ardakani ◽  
Hosu ◽  
Cristea ◽  
Mazloum-Ardakani ◽  
Marrazza

Neurotransmitters are endogenous chemical messengers which play an important role in many of the brain functions, abnormal levels being correlated with physical, psychotic and neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's disease. Therefore, their sensitive and robust detection is of great clinical significance. Electrochemical methods have been intensively used in the last decades for neurotransmitter detection, outclassing more complicated analytical techniques such as conventional spectrophotometry, chromatography, fluorescence, flow injection, and capillary electrophoresis. In this manuscript, the most successful and promising electrochemical enzyme-free and enzymatic sensors for neurotransmitter detection are reviewed. Focusing on the activity of worldwide researchers mainly during the last ten years (2010–2019), without pretending to be exhaustive, we present an overview of the progress made in sensing strategies during this time. Particular emphasis is placed on nanostructured-based sensors, which show a substantial improvement of the analytical performances. This review also examines the progress made in biosensors for neurotransmitter measurements in vitro, in vivo and ex vivo.


Biosensors ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 162
Author(s):  
Saheed E. Elugoke ◽  
Abolanle S. Adekunle ◽  
Omolola E. Fayemi ◽  
Bhekie B. Mamba ◽  
El-Sayed M. Sherif ◽  
...  

Imbalance in the levels of monoamine neurotransmitters have manifested in severe health issues. Electrochemical sensors have been designed for their determination, with good sensitivity recorded. Carbon-based quantum dots have proven to be an important component of electrochemical sensors due to their high conductivity, low cytotoxicity and opto-electronic properties. The quest for more sensitive electrodes with cheaper materials led to the development of electrochemical sensors based on carbon-based quantum dots for the detection of neurotransmitters. The importance of monoamine neurotransmitters (NTs) and the good electrocatalytic activity of carbon and graphene quantum dots (CQDs and GQDs) make the review of the efforts made in the design of such sensors for monoamine NTs of huge necessity. The differences and the similarities between these two quantum dots are highlighted prior to a discussion of their application in electrochemical sensors over the last ten years. Compared to other monoamine NTs, dopamine (DA) was the most studied with GQDs and CQD-based electrochemical sensors.


2015 ◽  
Vol 2 (1) ◽  
pp. 96 ◽  
Author(s):  
Arben Sahiti ◽  
Mejdi Bektashi

The problem relating with the accounting fraud is that it has not stopped despite the numerous changes that have been made in legislation and strict controls by the internal and external auditors. Therefore, the aim of this paper is to asess strategies and techniques available to use for accounting fraud detection. Also, this paper aims to assess the impact of fraud, and the role of auditors and the media in combating this phenomenon. This research will be carried out using secondary data because it fits better the aim and purpose of the research. Data used derived from a range of sources that have a very high degree of credibility and reliability, and which have been carefully reviewed by other relevant bodies for accuracy and quality purposes. This includes databases and various publications. In addition, the data also stem from individual and group publications made by renowned scientific researchers who have solid expertise in their field of accounting. Narrative analysis is used to analyze the data in this paper. This research will conclude that techniques used for the detection of fraud in accounting and various strategies can positively influence the treatment of this phenomenon due to the alarm buzzer for possible fraud. However, vigilance is necessarily required to add all parties involved in the corporation through the use of different anti-fraud programs to stimulate the accountability of the management executives and employees through informants to fight this destructive phenomenon.


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