scholarly journals Non-Traditional and Non-Invasive Approaches in Facial Rejuvenation: A Brief Review

Cosmetics ◽  
2020 ◽  
Vol 7 (1) ◽  
pp. 10 ◽  
Author(s):  
Abigail M. Smith ◽  
Taylor Ferris ◽  
Vinayak K. Nahar ◽  
Manoj Sharma
Keyword(s):  
Side Effects ◽  
Muscle Thickness ◽  
Alternative Therapies ◽  
Facial Rejuvenation ◽  
Medical Community ◽  
Facial Aging ◽  
Skin Laxity ◽  
Surgical Interventions ◽  
Non Invasive

While injectables, lasers, and surgical interventions have traditionally been used to reverse the changes associated with facial aging, other alternative therapies such as facial acupuncture and facial exercises are now being studied for facial rejuvenation. In this paper, we both summarize the concepts of facial acupuncture and facial exercises, and review seven studies that evaluate the efficacy of these modalities. Data from these studies suggest that both facial acupuncture and facial exercises have the potential to improve the skin laxity, wrinkle length, muscle thickness, and pigmentary changes associated with aging. Patients frequently reported improvement and experienced very few side effects. However, further research is necessary before these modalities are widely accepted as effective by the medical community, though the results of these studies may ultimately make providers less hesitant when patients seek out these services.

Combining Laser Resurfacing and Facial Rejuvenation Surgery

2021 ◽  
Vol 37 (02) ◽  
pp. 233-239
Author(s):  
Jill L. Hessler ◽  
Oscar Trujillo
Keyword(s):  
Synergistic Effect ◽  
Clinical Results ◽  
Facial Rejuvenation ◽  
Candidate Selection ◽  
Volume Loss ◽  
Facial Aging ◽  
Laser Resurfacing ◽  
Skin Laxity ◽  
Surgical Interventions ◽  
The Many

AbstractFacial aging is a multifactorial process involving skin laxity, volume loss, facial rhytids and solar elastosis. Surgical interventions can address the laxity of the skin and restore volume loss but do not fully correct the texture of the skin. Historically, there were concerns over the safety of combining laser resurfacing with facelifting procedures, but now there is much evidence to support the safe use of this combination treatment. When done appropriately, the combination of laser resurfacing with facial rejuvenation surgery can provide a synergistic effect for optimal clinical results. Here, we review the many laser options available and how they may be combined safely with surgical facial rejuvenation. We also review clinical contexts and candidate selection to provide safe, reliable results and minimize complications.

scholarly journals Non-surgical skin tightening

2021 ◽  
Author(s):  
Kelly O’Connor ◽  
Prasanthi Kandula ◽  
Michael Kaminer
Keyword(s):  
Patient Satisfaction ◽  
Side Effects ◽  
Patient Selection ◽  
Sun Exposure ◽  
Skin Tightening ◽  
Skin Laxity ◽  
Surgical Interventions ◽  
Physiologic Mechanism ◽  
Surgical Methods ◽  
Clinical Benefits

Skin laxity is an unavoidable consequence of aging and chronic sun exposure. Patients are increasingly turning to non-surgical skin tightening measures for a more youthful look. Non-surgical methods can be effective in treating mild to moderate skin laxity, while offering decreased downtimes and fewer serious complications than surgical interventions. This article reviews the major non-surgical interventions for skin laxity: ablative and non-ablative lasers, radiofrequency, and microfocused ultrasound, noting their physiologic mechanism of actions, clinical benefits, and side effects. Regardless of the procedure, patient selection and expectation setting are crucial to achieving desired results and ensuring patient satisfaction.

Chronic Asthma: An Update

1996 ◽  
Vol 17 (4) ◽  
pp. 111-117
Author(s):  
Kathi J. Kemper
Keyword(s):  
Side Effects ◽  
Alternative Therapies ◽  
Herbal Remedies ◽  
Chronic Asthma ◽  
Case Scenario ◽  
Mineral Supplements ◽  
Current Medication ◽  
Ma Huang ◽  
Potential Benefits ◽  
Routine Physical Examination

Case Scenario Having just changed insurance carriers, a mother brings her 13-year-old son to your office for a routine physical examination. He has no current complaints except for chronic asthma. His past medical history is significant for several hospitalizations for asthma. His only current medication is an albuterol inhaler that he uses two to three times daily. Further questioning about home remedies reveals that in an effort to cut down on his chronic use of medication, he recently started taking the herbal remedies Ma huang and Dong quai as well as vitamin and mineral supplements. He wants to know how safe and effective these therapies are and if you have any other suggestions to help him with his symptoms and avoid another hospitalization. Because of its severity and complexity, asthma and its treatment are often frustrating for patients, families, and clinicians. Out of desperation, many patients and families turn to alternative therapies, such as nutrition, herbs, and Chinese medicine. With the growing interest in and use of alternative therapies, practitioners would do well to become familiar with them, their side effects, and potential benefits. Traditional medical management also has changed; modern therapy emphasizes anti-inflammatory rather than bronchodilator medication. This review focuses on modern management of chronic asthma symptoms and highlights recent evidence about the effectiveness and side effects of alternative treatments.

scholarly journals Pharmacogenomics- The Promise of Personalized Medicine

2013 ◽  
Vol 12 (4) ◽  
pp. 346-356 ◽  
Author(s):  
M Fakruddin ◽  
A Chowdhury
Keyword(s):  
Side Effects ◽  
Personalized Medicine ◽  
Development Process ◽  
Genetic Basis ◽  
Ethical Issues ◽  
Medical Science ◽  
Medical Community ◽  
Pharmaceutical Companies ◽  
Current Therapies ◽  
Genetic Makeup

Introduction: Pharmacogenomics (PGx) is the study of the genetic basis of variability among individuals in response to drugs. It is the newest discipline of medicine and is becoming a very active area of research, with the pharmaceutical industry gaining experience applying it, integrating it into the drug development process, and also learning to better manage the expectations of the medical community. Methodology: A comprehensive review of the literature on the principles, applications, challenges and prospects of pharmacogenomics was performed. Results: Pharmacogenomics tailors therapies to the genetic makeup of an individual and can therefore offer treatments that are more efficacious and have fewer side effects. Despite these benefits, personalized medicine has not been embraced by large pharmaceutical companies. It is expected that the first wave of successful pharmacogenomics products will be used in acute treatments for which current therapies have and severe side effects. These products should also be good candidates for premium pricing. Personalized medicine (PM), based on the genetic makeup of a patient, may result in not only an improved therapeutic response but also a clinically important reduction in adverse drug reactions. The experience to date is mixed, with a few successes but many frustrations. Conclusion: However, for pharmacogenomics to be truly embraced, the benefits of this technology must become more widely accepted in terms of economic, public, regulatory and ethical issues. DOI: http://dx.doi.org/10.3329/bjms.v12i4.11041 Bangladesh Journal of Medical Science Vol. 12 No. 04 October ’13 Page 346-356

The olfactory system in Alzheimer’s disease: Pathology, pathophysiology and pathway for therapy

2013 ◽  
Vol 4 (1) ◽  
Author(s):  
Tibor Kovács
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Side Effects ◽  
Olfactory System ◽  
Therapeutic Agents ◽  
Non Invasive ◽  
Degenerative Disorders ◽  
Invasive Method

AbstractOlfaction is frequently mentioned as a “neglected sense”, although the olfactory system has several interesting and unique anatomical and physiological features. Olfactory involvement is present in several degenerative disorders, especially in Alzheimer’s disease (AD). The peripheral and central parts of the olfactory system are damaged even in the early stages of AD, manifesting in profound olfactory deficits. Besides the early pathology, the olfactory system may be involved in the pathogenesis of AD by providing a route of entry for pathological agents still unknown. In contrast to this olfactory vector hypothesis, the olfactory system can be used to deliver therapeutic agents in AD, such as nerve growth factor and insulin, by decreasing the side-effects of the therapy or providing a non-invasive method of delivery.

scholarly journals Fat Grafting for Facial Rejuvenation

2020 ◽  
Vol 34 (01) ◽  
pp. 030-037 ◽  
Author(s):  
Kelly P. Schultz ◽  
Anjali Raghuram ◽  
Matthew J. Davis ◽  
Amjed Abu-Ghname ◽  
Edward Chamata ◽  
...  
Keyword(s):  
Fat Grafting ◽  
Facial Rejuvenation ◽  
Nasolabial Fold ◽  
Volume Depletion ◽  
Systematic Method ◽  
Face Lift ◽  
Facial Aging ◽  
Native Tissue ◽  
The Face ◽  
Injectable Fillers

AbstractFor optimal results, facial rejuvenation procedures should address both the tissue laxity and volume deflation associated with facial aging. The lift-and-fill face lift, in which fat grafting provides volumetric rejuvenation to the face while surgical lift effectively repositions and removes ptotic and redundant tissue, has revolutionized the plastic surgeon's approach to the aged face. An understanding of the intricate anatomy of distinct facial fat compartments and a systematic method to assess areas of fat atrophy and volume depletion are keys to provide patients with a natural and youthful result. Fat grafting may be used to improve contour in any area treatable by nonautologous injectable fillers, including the temples, forehead, upper and lower orbit, cheeks, perioral region, nasolabial fold, jawline, and chin—with the benefit of a more natural contour and integration with native tissue.

scholarly journals AGE-SPECIFIC VIEWS ON INVASIVE AND NON-INVASIVE HUMAN ENHANCEMENTS FOR COGNITIVE DECLINE

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S327-S328
Author(s):  
G Rainville ◽  
Laura Skufca ◽  
Madeline Eller
Keyword(s):  
Public Health ◽  
Side Effects ◽  
Cognitive Decline ◽  
Age Groups ◽  
Older Americans ◽  
Health Implications ◽  
Non Invasive ◽  
Two Age Groups

Abstract This research examines the degree to which younger and older Americans approve of addressing cognitive decline using either a pill-based or an implant-based intervention to restore prior functioning. Half of a probability-based online sample expressed concerns over side effects and levels of approval for a pill-based intervention whereas the remainder of the sample did so for a relatively invasive implant-based enhancement (data were interviews of 2,025 American adults gathered by NORC’s AmeriSpeak panel as part of the AARP Human Enhancements study). We predicted and found that relative disapproval of the implant-based intervention was only significant among those with high concerns over side effects. However, when looking at two age groups for which cognitive decline differed in salience, relative disapproval of the implant-based enhancements were relatively stronger for those 50 and older even among those with few concerns over side effects. This age-based aversion to invasive forms of enhancements may have public health implications in that the subgroup who may most-immediately benefit from the enhancement and may be in the market for only non-invasive enhancements. It is not clear if such enhancements, however, could be delivered via a pill or other non-invasive forms.

scholarly journals Facial aging: A clinical classification

2007 ◽  
Vol 40 (02) ◽  
pp. 178-180
Author(s):  
Melvin A Shiffman
Keyword(s):  
Aging Process ◽  
Facial Rejuvenation ◽  
Clinical Classification ◽  
Facial Aging ◽  
Clinical Method ◽  
Chemical Peels ◽  
The Face ◽  
Quick Estimate

ABSTRACTthe purpose of this classification of facial aging is to have a simple clinical method to determine the severity of the aging process in the face. this allows a quick estimate as to the types of procedures that the patient would need to have the best results. procedures that are presently used for facial rejuvenation include laser, chemical peels, suture lifts, fillers, modified facelift and full facelift. the physician is already using his best judgment to determine which procedure would be best for any particular patient. this classification may help to refine these decisions.

scholarly journals Effectiveness of a New Recombinant antiGnRH Vaccine for Immunocastration in Bulls

Animals ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1359
Author(s):  
Paula R. Huenchullan ◽  
Sonia Vidal ◽  
Rafael Larraín ◽  
Leonardo Saénz
Keyword(s):  
Side Effects ◽  
Companion Animals ◽  
Surgical Techniques ◽  
Surgery Complications ◽  
Safe Alternative ◽  
Recombinant Peptide ◽  
Adverse Side Effects ◽  
Non Invasive ◽  
Post Surgery ◽  
Commercial Viability

Castration by surgical techniques is common in livestock; however, post-surgery complications and concerns for animal wellbeing have created a need for new non-invasive alternatives. The objective of this study was to evaluate immunocastration in bulls using antigen GnRX G/Q; a recombinant peptide proved to be effective in laboratory and companion animals. A nine-month trial with 80 9-month-old Normand x Hereford bulls, kept in a pastured system, was conducted. The herd was divided in half with 40 bulls surgically castrated (SC) and 40 castrated by immunization against GnRH (IC). The antigen was injected on days 0 and 40 of the experiment. After the second dose, the IC group had elevated GnRH antibodies and decreased testosterone levels (below 5 ng/mL) that were maintained for 23 weeks. At slaughter on day 190, the immunocastrated group obtained a higher weight, hot carcass, and dressing percentage than the SC group. There was no difference in pH, color of meat, fat coverage, cooking loss, or tenderness between groups. The bulls showed no inflammatory reaction at the injection site or adverse side effects from the vaccine. Our results demonstrate that immunocastration with GnRX G/Q is an efficient and safe alternative to surgical castration in livestock. Additional work evaluating antigen effects over a longer period is needed to validate commercial viability.

Current and Emerging Therapies for Ocular Rosacea

2013 ◽  
Vol 06 (02) ◽  
pp. 86
Author(s):  
Edward J Wladis ◽  
Alejandro P Adam ◽  
◽  
Keyword(s):  
Side Effects ◽  
Therapeutic Strategies ◽  
Treatment Modalities ◽  
Surgical Interventions ◽  
Oral Medications ◽  
Incurable Disease ◽  
Emerging Therapies ◽  
Improved Outcomes ◽  
Ocular Rosacea ◽  
Intense Research

Ocular rosacea is an incurable disease that affects millions of Americans annually. While multiple therapeutic strategies have been devised to address this disorder (including topical and oral medications, laser and light-based treatments, and surgical interventions), our current interventions are largely nonspecific and often ineffective. Nonetheless, ocular rosacea remains a source of intense research, and newer treatments offer tremendous promise for improved outcomes. In this review, we discuss the current and emerging treatment modalities for ocular rosacea and analyze novel basic science findings that will hopefully lead to highly targeted medications to treat this potentially blinding illness with greater specificity and fewer side effects.

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