scholarly journals Synthesis, Spectroscopic, and Biological Assessments on Some New Rare Earth Metal Adrenaline Adducts

Crystals ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 1536
Author(s):  
Sulaiman A. Al Yousef ◽  
Asma S. Al-Wasidi ◽  
Ibtisam I. S. AlZahrani ◽  
Hotoun I. Thawibaraka ◽  
Ahmed M. Naglah ◽  
...  
Keyword(s):  
Metal Ion ◽  
Laser Scanning ◽  
Earth Metal ◽  
Raman Laser ◽  
Central Metal ◽  
Infrared Spectral ◽  
Metal Adducts ◽  
Antibacterial And Antifungal ◽  
New Compounds ◽  
Biological Assessments

Adrenaline (Adr) reacts with chlorides of Y3+, Ce3+, Nd3+ and Sm3+ in methanol at 60 °C to yield metal ion adducts of definite composition. These compounds are characterized by elemental analyses, molar conductivity, UV-Vis., 1H–NMR, Raman laser, scanning electron microscopy, energy-dispersive X-ray spectroscopy (EDX), and mid infrared spectral measurement investigations. The adducts are found to have the formulae [Y2(Adr)2(H2O)8]Cl3.8H2O, [Ce(Adr)2(H2O)2]Cl3.10H2O, [Nd(Adr)2(H2O)2]Cl3.6H2O, and [Sm(Adr)2(H2O)2]Cl3.12H2O, respectively. The two phenolic groups of the catechol moiety are linked to central metal ions based on the infrared and Raman laser spectra. The new compounds were tested against five gram-positive and two-gram negative bacteria, in addition to two Aspergillus strains. Metal adducts were shown to have stronger antibacterial and antifungal properties than free adrenaline compounds.

Preparation and Luminescent Properties of the La3+ Doped Tb3+-Hydroxyapatite

2014 ◽  
Vol 716-717 ◽  
pp. 32-35
Author(s):  
Wen Bin Liu ◽  
Adu ◽  
Yu Guang Lv ◽  
Li Li Yu ◽  
Yong Xiang Du ◽  
...  
Keyword(s):  
Rare Earth ◽  
Metal Ion ◽  
Chemical Properties ◽  
Earth Metal ◽  
Luminescent Properties ◽  
Central Metal ◽  
X Ray Diffraction ◽  
Light Emitting ◽  
Terbium Ion ◽  
The Stability

In this paper, a rare earth metal terbium ion as the central metal ion, a nanohydroxyapatite powder of the lanthanum doped terbium was synthesis by precipitation with hydroxyapatite as ligand. The sample was characterized by infrared spectrum, fluorescence spectrum and X ray diffraction instrument, and the thermal properties and fluorescence properties, structure of powderes were discussed. A nanohydroxyapatite powder of the lanthanum doped terbium achieves the maximum luminous intensity, when the La3+ doping concentration of Tb3+ was HAP 5% (La3+ and Tb3+ mole fraction ratio) devices. Rare earth powder of the lanthanum doped terbium hydroxyapatite has the stability chemical properties, the luminescence properties and good biological activity, the rare earth powder has good luminescent properties can be used in preparation of a good light emitting device. At the same time a nanohydroxyapatite powder of the lanthanum doped terbium has good antibacterial property, can be used as antibacterial materials.

MODIFICATION OF NORMAL-STATE AND SUPERCONDUCTING PROPERTIES OF HIGH-Tc OXIDES VIA TREATMENT BY METAL-PHTHALOCYANINES

1994 ◽  
Vol 08 (05) ◽  
pp. 615-639 ◽  
Author(s):  
LEONID GRIGORYAN ◽  
KYUYA YAKUSHI ◽  
A. V. NARLIKAR ◽  
P. K. DUTTA ◽  
S. B. SAMANTHA
Keyword(s):  
Metal Ion ◽  
Scanning Tunneling ◽  
Zero Field ◽  
Central Metal ◽  
Tunneling Microscopy ◽  
Absorption Data ◽  
Metal Phthalocyanines ◽  
Oxide Powders ◽  
Lower Magnitude ◽  
New Compounds

Exposure of Bi- or Tl-based high-T c oxide powders to vapors of metal-phthalocyanines MPc (M is Zn or Ni) resulted in the formation of a family of new compounds with modified crystal lattice parameters, electronic structure, phonon spectrum and magnetic properties as compared to the starting materials. Based on the combined X ray diffraction, scanning tunneling microscopy, optical, FT–IR and microwave absorption data, a model of crystal structure is proposed where the key feature is intercalation of MPc molecules between the Bi-O (Tl-O) bilayers. Values of dc magnetization at 300 K varied over two orders of magnitude as a function of chemical composition and nature of the central metal ion in MPc. Measurements of temperature dependence of magnetization of the intercalated samples revealed a divergence at low temperatures between the zero-field and the field-cooled cycles, though of lower magnitude as compared to the starting high-T c oxides. The results of this study suggest that treatment by MPc offers a possibility of controllable variation of key properties of high-T c oxides.

Protonation effects on dynamic flux properties of aqueous metal complexes

2009 ◽  
Vol 74 (10) ◽  
pp. 1543-1557 ◽  
Author(s):  
Herman P. Van Leeuwen ◽  
Raewyn M. Town
Keyword(s):  
Complex Formation ◽  
Metal Ion ◽  
Good Description ◽  
Minor Component ◽  
Outer Sphere ◽  
Metal Species ◽  
Central Metal ◽  
Inner Sphere ◽  
A Minor ◽  
Protonated Ligand

The degree of (de)protonation of aqueous metal species has significant consequences for the kinetics of complex formation/dissociation. All protonated forms of both the ligand and the hydrated central metal ion contribute to the rate of complex formation to an extent weighted by the pertaining outer-sphere stabilities. Likewise, the lifetime of the uncomplexed metal is determined by all the various protonated ligand species. Therefore, the interfacial reaction layer thickness, μ, and the ensuing kinetic flux, Jkin, are more involved than in the conventional case. All inner-sphere complexes contribute to the overall rate of dissociation, as weighted by their respective rate constants for dissociation, kd. The presence of inner-sphere deprotonated H2O, or of outer-sphere protonated ligand, generally has a great impact on kd of the inner-sphere complex. Consequently, the overall flux can be dominated by a species that is a minor component of the bulk speciation. The concepts are shown to provide a good description of experimental stripping chronopotentiometric data for several protonated metal–ligand systems.

Effects of substituent groups and central metal ion on hydrogen adsorption in zeolitic imidazolate frameworks

2013 ◽  
Vol 97 ◽  
pp. 60-66 ◽  
Author(s):  
Er-Yu Chen ◽  
Ying-Chun Liu ◽  
Tian-Yang Sun ◽  
Qi Wang ◽  
Li-Jun Liang
Keyword(s):  
Metal Ion ◽  
Hydrogen Adsorption ◽  
Central Metal ◽  
Zeolitic Imidazolate Frameworks

MetLigDB: a web-based database for the identification of chemical groups to design metalloprotein inhibitors

2011 ◽  
Vol 44 (4) ◽  
pp. 878-881 ◽  
Author(s):  
Hwanho Choi ◽  
Hongsuk Kang ◽  
Hwangseo Park
Keyword(s):  
Drug Discovery ◽  
Metal Ions ◽  
Metal Ion ◽  
Central Metal ◽  
Amino Acid Residues ◽  
Web Based ◽  
Additional Information ◽  
Chemical Groups ◽  
Insight Into ◽  
Chelating Groups

MetLigDB (http://silver.sejong.ac.kr/MetLigDB) is a publicly accessible web-based database through which the interactions between a variety of chelating groups and various central metal ions in the active site of metalloproteins can be explored in detail. Additional information can also be retrieved, including protein and inhibitor names, the amino acid residues coordinated to the central metal ion, and the binding affinity of the inhibitor for the target metalloprotein. Although many metalloproteins have been considered promising targets for drug discovery, it is difficult to discover new inhibitors because of the difficulty in designing a suitable chelating moiety to impair the catalytic activity of the central metal ion. Because both common and specific chelating groups can be identified for varying metal ions and the associated coordination environments, MetLigDB is expected to give users insight into designing new inhibitors of metalloproteins for drug discovery.

New soluble 4-(4-formyl-2,6-dimethoxyphenoxy) substituted phthalocyanines: Synthesis, characterization, photophysical and photochemical properties

2021 ◽  
pp. 1-10
Author(s):  
Ibrahim Erden ◽  
Betül Karadoğan ◽  
Fatma Aytan Kılıçarslan ◽  
Göknur Yaşa Atmaca ◽  
Ali Erdoğmuş
Keyword(s):  
Quantum Yield ◽  
Singlet Oxygen ◽  
Fluorescence Quantum Yield ◽  
Metal Ion ◽  
Mass Spectra ◽  
Quantum Yields ◽  
Therapeutic Outcomes ◽  
Ft Ir ◽  
Photochemical Properties ◽  
New Compounds

This work describes the synthesis, spectral and fluorescence properties of bis 4-(4-formyl-2,6-dimethoxyphenoxy) substituted zinc (ZnPc) and magnesium (MgPc) phthalocyanines. The new compounds have been characterized by elemental analysis, UV-Vis, FT-IR, 1H-NMR and mass spectra. Afterward, the effects of including metal ion on the photophysicochemical properties of the complexes were studied in biocompatible solvent DMSO to analyze their potential to use as a photosensitizer in photodynamic therapy (PDT). The fluorescence and singlet oxygen quantum yields were calculated as 0.04–0.15 and 0.70–0.52 for ZnPc and MgPc, respectively. According to the results, MgPc has higher fluorescence quantum yield than ZnPc, while ZnPc has higher singlet oxygen quantum yield than MgPc. The results show that the synthesized complexes can have therapeutic outcomes for cancer treatment.

scholarly journals Development of Antibacterial and Antifungal Triazole Chromium(III) and Cobalt(II) Complexes: Synthesis and Biological Activity Evaluations

Molecules ◽  
2018 ◽  
Vol 23 (8) ◽  
pp. 2013 ◽  
Author(s):  
Ricardo Murcia ◽  
Sandra Leal ◽  
Martha Roa ◽  
Edgar Nagles ◽  
Alvaro Muñoz-Castro ◽  
...  
Keyword(s):  
Electrical Conductivity ◽  
Biological Activity ◽  
Melting Point ◽  
Inhibitory Concentration ◽  
Vero Cells ◽  
Visible Spectroscopy ◽  
Antifungal Activities ◽  
Antibacterial And Antifungal Activities ◽  
Antibacterial And Antifungal ◽  
New Compounds

In this work, six complexes (2–7) of Cr(III) and Co(II) transition metals with triazole ligands were synthesized and characterized. In addition, a new ligand, 3,5-bis(1,2,4-triazol-1-ylmethyl)toluene (1), was synthesized and full characterized. The complexes were obtained as air-stable solids and characterized by melting point, electrical conductivity, thermogravimetric analysis, and Raman, infrared and ultraviolet/visible spectroscopy. The analyses and spectral data showed that complexes 3–7 had 1:1 (M:L) stoichiometries and octahedral geometries, while 2 had a 1:2 (M:L) ratio, which was supported by DFT calculations. The complexes and their respective ligands were evaluated against bacterial and fungal strains with clinical relevance. All the complexes showed higher antibacterial and antifungal activities than the free ligands. The complexes were more active against fungi than against bacteria. The activities of the chromium complexes against Candida tropicalis are of great interest, as they showed minimum inhibitory concentration 50 (MIC50) values between 7.8 and 15.6 μg mL−1. Complexes 5 and 6 showed little effect on Vero cells, indicating that they are not cytotoxic. These results can provide an important platform for the design of new compounds with antibacterial and antifungal activities.

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