scholarly journals Migration of Cefquinome Antibiotic Residues from Milk to Dairy Products

Dairy ◽  
2021 ◽  
Vol 2 (4) ◽  
pp. 658-670
Author(s):  
Melissa Di Rocco ◽  
Johann Scollard ◽  
Riona Sayers ◽  
Ambrose Furey ◽  
Martin Danaher ◽  
...  
Keyword(s):  
Dairy Products ◽  
Animal Studies ◽  
Solid Phase ◽  
High Water ◽  
Dispersive Solid Phase Extraction ◽  
Target Concentration ◽  
Measured Concentration ◽  
Skimmed Milk ◽  
The Difference ◽  
Ultrahigh Performance Liquid Chromatography

The aim of this study was to investigate the distribution of cefquinome in different dairy products during the processing of naturally contaminated milk or spiked milk. The analysis of cefquinome residues in milk, skimmed milk, buttermilk, whey, cream, butter, curd, and cheese samples was performed using a water:acetonitrile solvent extraction and C18 dispersive solid-phase extraction (d-SPE) clean-up, followed by ultrahigh-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC–MS/MS) determination. The target concentration of cefquinome was achieved in the spiked milk (100 µg kg−1). During its processing, the antibiotic migrated primarily with the skimmed milk as opposed to cream (ratios of 3.6:1 and 2.8:1 for experiments A and B, respectively), and with the buttermilk during butter manufacture (ratios of 6.9:1 and 4.6:1), but was equal in the curd and whey during the manufacture of cheese. In the milk collected from treated animals, the measured concentration of cefquinome was considerably high (approx. 5000 µg kg−1). The results obtained from the dairy products were similar to those obtained in the spiked study (ratios of 8.2:1 and 3.1:1 for experiments A and B, respectively, during the separation of skimmed milk and cream; 6.0:1 and 5.0:1 for A and B, respectively, during the separation of buttermilk and butter). However, during cheesemaking, cefquinome migrated with the whey after cutting the curd, with ratios of 0.54:1 and 0.44:1 for experiments A and B, respectively. The difference in the migration of cefquinome between curd and whey in spiked and animal studies is probably due to the different concentration levels in the two different experiments. The results of this study showed that, in dairy products manufactured from milk containing cefquinome residues, the drug migrated primarily with the high-water-containing fractions.

High-Throughput Quantification of Monofluoroacetate (1080) in Milk as a Response to an Extortion Threat

2016 ◽  
Vol 79 (2) ◽  
pp. 273-281 ◽  
Author(s):  
TERRY P. COONEY ◽  
PETER VARELIS ◽  
JUSTIN G. BENDALL
Keyword(s):  
Liquid Chromatography ◽  
High Throughput ◽  
Dairy Products ◽  
Solid Phase ◽  
High Specificity ◽  
Limit Of Quantification ◽  
Analytical Methodology ◽  
Liquid Chromatography Tandem Mass ◽  
Ultrahigh Performance Liquid Chromatography ◽  
Fluid Milk

ABSTRACTAs a food defense measure against an extortion threat to poison infant formula with monofluoroacetate, a robust methodology for monofluoroacetate analysis in fluid milk and powdered dairy products was developed and optimized. Critical challenges posed by this situation required that the analytical methodology provide (i) high specificity, (ii) high throughput capable of analyzing thousands of samples of fluid milk per day, and (iii) trace-level detection of 1 ng/g or lower to achieve the maximum residue limit. Solid-phase extraction–purified acetone extracts of fluid milk were derivatized with aniline, and after ultrahigh-performance liquid chromatography using a Kinetex-C18 column packed with 1.3-μm shell particles, the resulting N-phenyl 2-fluoroacetamide could be determined by liquid chromatography–tandem mass spectrometry in a highly specific manner and with a limit of quantification of 0.5 ng/ml. By using 4-(4-chlorophenoxy)aniline as a derivatizing agent, the method could be extended to powdered dairy products with the same limit of quantification. Between January and July 2015, some 136,000 fluid milk samples were tested using this method. This analytical testing of fluid milk formed one element in a larger program of work by multiple agencies to ensure that consumers could continue to have confidence in the safety of New Zealand milk and dairy products.

scholarly journals The Water Footprint of Primary and Secondary Processing of Beef from Different Cattle Breeds: A Value Fraction Allocation Model

2021 ◽  
Vol 13 (12) ◽  
pp. 6914
Author(s):  
Frikkie Alberts Maré ◽  
Henry Jordaan
Keyword(s):  
Water Footprint ◽  
Negative Relationship ◽  
High Water ◽  
Allocation Model ◽  
Cattle Breeds ◽  
A Value ◽  
Average Production ◽  
High Water Intake ◽  
The Difference ◽  
By Products

The high water intake and wastewater discharge of slaughterhouses have been a concern for many years. One neglected factor in previous research is allocating the water footprint (WF) to beef production’s different products and by-products. The objective of this article was to estimate the WF of different cattle breeds at a slaughterhouse and cutting plant and allocate it according to the different cuts (products) and by-products of beef based on the value fraction of each. The results indicated a negative relationship between the carcass weight and the processing WF when the different breeds were compared. Regarding a specific cut of beef, a kilogram of rib eye from the heaviest breed had a processing WF of 614.57 L/kg, compared to the 919.91 L/kg for the rib eye of the lightest breed. A comparison of the different cuts indicated that high-value cuts had higher WFs than low-value cuts. The difference between a kilogram of rib eye and flank was 426.26 L/kg for the heaviest breed and 637.86 L/kg for the lightest breed. An option to reduce the processing WF of beef is to lessen the WF by slaughtering heavier animals. This will require no extra investment from the slaughterhouse. At the same time, the returns should increase as the average production inputs per kilogram of output (carcass) should reduce, as the slaughterhouse will process more kilograms.

Sign in / Sign up

Export Citation Format

Share Document