scholarly journals Diagnosis of Dizziness Due to a Core Vestibular Projection Injury in a Patient with Intracerebral Hemorrhage

Diagnostics ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 220 ◽  
Author(s):  
Hyeok Gyu Kwon ◽  
Chul Hoon Chang ◽  
Sung Ho Jang

Herein, we present a patient diagnosed with dizziness due to a core vestibular projection injury following intracerebral hemorrhage (ICH). A 51-year-old female patient underwent conservative management for a spontaneous ICH in the left hemisphere (mainly affecting the basal ganglia and insular cortex). When she visited the rehabilitation department of the university hospital at two years after the ICH onset, she advised of the presence of moderate dizziness (mainly, light-headedness) that started after ICH onset. She mentioned that her dizziness had decreased slightly over time. No abnormality was observed in the vestibular system of either ear on physical examination by an otorhinolaryngologist. However, diffusion tensor tractography results showed that the core vestibular projection in the left hemisphere was discontinued at the basal ganglia level compared with the patient’s right core vestibular projection and that of a normal subject. Therefore, it appears that the dizziness in this patient can be ascribed to a left core vestibular projection injury.

2019 ◽  
Vol 109 (2) ◽  
pp. 214-237 ◽  
Author(s):  
Nicolò Marchetti ◽  
Abbas Al-Hussainy ◽  
Giacomo Benati ◽  
Giampaolo Luglio ◽  
Giulia Scazzosi ◽  
...  

Abstract This paper draws on the preliminary results of the QADIS survey project, conducted by the University of Bologna and the Iraqi State Board of Antiquities and Heritage since 2016 in the Qadisiyah province. The project addresses phenomena related to anthropogenic transformation of landscapes in a region that was at the core of the early Mesopotamian urbanization process. Building upon the seminal work conducted by R. McC. Adams in the 1960 s and 1970 s, we implemented an integrated documentation technique to reconstruct at regional levels the changes in the dense network of human settlements and artificial water infrastructures characterizing the evolution of this archaeological landscape over time. The aim of the article is that of providing a finer-grained regional picture of 4th and 3rd millennium BC urban developments which can be useful for better conceptualizing the scale and pace of early Mesopotamian urbanism.


2019 ◽  
Vol 12 (1) ◽  
pp. 34-42 ◽  
Author(s):  
Merita Hysenbegasi ◽  
◽  
Ives Hubloue ◽  
Rita Vanobberghen ◽  
Jan Kartounian ◽  
...  

Walk-in patients who do not require urgent treatment at an emergency department (ED) are a known and long-standing problem. This study aims to investigate the characteristics of walk-in patients visiting the ED over time. During four days in June 2012, all walk-in patients attending the ED of the University Hospital Brussels between 8 AM and 11 PM were recorded. A similar registration took place in the same ED in June 2001. Patients completed a questionnaire about their characteristics and the reason for the encounter. Data of both study periods were compared. The mean age of the patients attending the ED was significantly lower in 2001 (40.9 years) than in 2012 (43.9 years) (p=0,02). In 2001, 81% of the participants had Belgian nationality, but in 2012 this proportion increased to 90% (p=0.008). In 2001 as well as in 2012, 21% of the participants had a referral from their family physician (FP) (p=0.9). The proportion of patients that were aware that FP could also handle some emergencies increased from 17% in 2001 to 29% in 2012 (p=0.003). More patients had complaints that begun less than 24h before they attended the ED (48% in 2001 and 58% in 2012) (p=0.03). The walk-in patients at the ED are getting slightly older and are attending the ED faster after the onset of the complaints. More patients judge their complaints as urgent. However, more patients are getting aware that FP also could handle some emergencies.


2005 ◽  
Vol 50 (2) ◽  
pp. 359-377 ◽  
Author(s):  
Hannelore Lee-Jahnke

AbstractAfter a brief description of the state of the art, this paper presents new methods of process-oriented translation training. The different instruments used in class, such as questionnaires and other tools, the learning outcome of these methods and the improvement of proficiency achieved by these means, constitute the core of the paper. The third and final part deals with the preliminary results of an interdisciplinary research project with the Department of Neurology of the University Hospital of Geneva, and the prospects for applying this type of research to translation training.


2019 ◽  
pp. 121-142
Author(s):  
Axel Mjærum ◽  
Steinar Solheim

The archaeological field course is the forum where many archaeology students meet and take part in an archaeological excavation for the first time. To excavate and generate scientific data through excavations is at the core of the archaeological discipline. For that reason, introducing students for theoretical and practical knowledge about field archaeology have been a central part of the discipline for the last 150 years at Norwegian universities. In this paper, we look closer at how the field course has developed at the University of Oslo during the last half century. Based on a compiled overview of field courses, we discuss how the field course has developed and changed over time in relation to the development in the discipline and higher education at large. A central question is whether the field course succeed in giving the students skills to perform an excavation and document the process. A main find is that collegial knowledge transfer run as a thread through the disciplines’ history as the most important way of training new archaeologists.


Author(s):  
Judith Favish ◽  
Janice L. McMillan

Challenges facing the higher education sector globally include questions over what counts as knowledge and what are valid forms of both its reproduction and production. This paper addresses the question of how what counts as valid knowledge is challenged and how it changes over time. It does this via an analysis of examples of social responsiveness profiled as 'portraits of practice' in the annual social responsiveness reports produced at the University of Cape Town, South Africa, a traditionally strong research university. In this paper, we discuss and analyse key themes emerging from this work and argue that social responsiveness not only serves to enhance the core functions of teaching and research but can act to change them.


Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Rebecca McCourt ◽  
Taurian Guinand ◽  
Laura Gioia ◽  
Mahesh Kate ◽  
Sarah Treit ◽  
...  

Background: Mortality can be predicted by intracerebral hemorrhage (ICH) volume, but motor recovery in survivors is variable. Motor impairment is likely related to the spatial relationship between the hematoma and corticospinal tract (CST). Diffusion Tensor Imaging (DTI) tractography can be used to visualize white matter tracts in three dimensions. We hypothesized that the interaction between the hematoma and CST would predict motor impairment in ICH patients. Methods: ICH patients with small-moderate hematomas were prospectively imaged with CT and DTI within 14 days of onset. Hematoma volume was assessed on CT using planimetric techniques. Three-dimensional recreations of the ipsilateral CST and the hematoma were made for each patient. The CST was categorized by interaction with the ICH as CST: Unaffected, Displaced, Partially Severed, Completely Severed, and Splitting the ICH. Motor function was classified as 'good' (NIHSS motor subscale 0-2) or 'poor' (3-8). Results: Thirty patients (mean age 68±13) underwent CT at a median (IQR) of 2.3 (3.5)h and DTI at 2.0 (3.6, range 0.6-13) days. Median hematoma volume was 8.2 (23) ml. Lesion distribution was: lobar 11 (37%), basal ganglia 18 (60%), brainstem 1 (3%). CSTs were primarily Displaced (n=9) or Unaffected (8), with the remainder being Partially Severed (4), Completely Severed (5), and Splitting the ICH (4). The latter 4 (13%) patients had small (<6ml, median 2.5 [3.0] ml) basal ganglia bleeds which enfolded the intact CST. Motor score at Day 7 was good in 50% of patients. Good outcome was seen in 8 (100%) Unaffected, 4 (44%) Displaced, 1 (25%) Partially Severed, 0 (0%) Severed and 2 (50%) Splitting the ICH patients. Logistic regression indicated that good motor score was predicted by CST category (r=2.3, p=0.016). Conclusion: CST integrity can be maintained when enfolded by small basal ganglia bleeds. Diffusion tractography patterns may be useful for predicting motor scores in small to moderate-sized hematomas.


2020 ◽  
Vol 7 (11) ◽  
Author(s):  
Majdouline El Moussaoui ◽  
Iseult Lambert ◽  
Nathalie Maes ◽  
Anne-Sophie Sauvage ◽  
Frédéric Frippiat ◽  
...  

Abstract Background Polypharmacy and drug interactions are important issues for HIV-infected individuals. The number and nature of those interactions are continuously evolving with the use of new antiretroviral drugs and the aging of HIV-infected individuals. We aimed to analyze this evolution over time. Methods This retrospective cohort study was conducted in the University Hospital of Liège (Belgium). Treatments of HIV-infected outpatients attending Liège University Hospital were collected and analyzed in 2012 and 2016. The University of Liverpool HIV drug interactions database was used to determine drug interactions. Results We included 1038 patients in 2016, of whom 78% had 1 comedication. Polypharmacy was seen in 20% of the cohort. Four percent of the patients presented red flag interactions, and 38% had orange flag interactions. Nonantiretroviral (non-ARV) therapeutic classes involved in drug interactions were mostly cardiovascular and central nervous system drugs. They were followed by hormone drugs and dietary supplements for orange flag interactions. Two factors significantly contributed to both red and orange flag interactions: the number of non-ARV comedications and protease inhibitor–based ARV regimens. The proportion of patients with red or orange flag interactions remained stable from 2012 to 2016. Conclusions This study highlights the persistence of an alarming number of contraindicated drug interactions and a high prevalence of potential drug interactions over time. Identification, prevention, and management of drug interactions remain a key priority in HIV care.


2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Khayra Sbahi ◽  
Brahim Kacem ◽  
Randa Talhi ◽  
Aicha Azaiz ◽  
Abderahmane Attar ◽  
...  

Abstract Background Urolithiasis is a pathology that changes with time and with the evolution of human societies. The prevalence of this pathology has gradually increased during the last decades, especially because of dietary changes. Methods This work is a retrospective descriptive epidemiological study of the temporal type carried out at the level of the urology service of the University Hospital Center of Oran between the first January 1965 and December 31, 2014. The objectives of this work are to study the epidemiological profile of urolithiasis and to determine the evolutionary trend of the disease over time. Results This study confirms some current data in the direction of an increase in surgical activity concerning the treatment of urinary stones. The analysis over time shows us a significant decrease (p < 0.01) in the male predominance between 1965 and 2014 with a M/F ratio which decreased from 3.09 to 1.82, as well as an increase in the average age, rising from 28.8 years in the period 1965–1974 to 48.3 years between 2005 and 2014. Conclusion The analysis of epidemiological data is essential to better evaluate the evolution of the urolithiasis disease, which was affirmed in our study, where a constant evolution of the characteristics of the disease was revealed, testifying the change of the socio-economic level in Algeria.


Stroke ◽  
2021 ◽  
Author(s):  
Christopher J. Love ◽  
Daniel Kirschenbaum ◽  
Magdy Selim ◽  
Eng H. Lo ◽  
Elisabeth Rushing ◽  
...  

Background and Purpose: The classic presentation of chronic (stage III) hemorrhagic stroke lesions is a fluid-filled cavity. In one of the most commonly used animal models of intracerebral hemorrhage (ICH), we noticed additional solid material within the chronic lesion. We examined the composition of those chronic ICH lesions and compared them with human autopsy cases. Methods: ICH was induced in rats by the injection of collagenase in the striatum. Tissue sections after hematoma resolution corresponding to 3 different chronic time points—28, 42, and 73 to 85 days post-ICH—were selected. Human autopsy reports at the University Hospital of Zurich were searched between 1990 and 2019 for ICH, and 3 chronic cases were found. The rat and human sections were stained with a variety of histopathologic markers. Results: Extensive collagenous material was observed in the chronic lesion after hematoma resolution in both the rat model and human autopsy cases. Additional immunostaining revealed that the material consisted primarily of a loose network of collagen 3 intermingled with occasional GFAP (glial fibrillary acidic protein)-positive processes and collagen 4. Conclusions: A key feature of the chronic ICH lesion is a loose network of collagen 3. The collagenase rat model reproduces the morphology and composition of the chronic human ICH lesion. While identifying new features of ICH lesion pathology, these results are important for treatment and recovery strategies.


Sign in / Sign up

Export Citation Format

Share Document