Depression and Anxiety Symptoms in UK Thalidomide Survivors: A Brief Survey

Between 1958 and 1961, the drug Thalidomide was prescribed in the UK as a treatment for morning sickness. It caused severe birth defects. Thalidomide survivors are now experiencing a range of secondary health problems, including depression and anxiety. Internationally, it is estimated that 40% to 50% of Thalidomide survivors have recently experienced common mental health problems. The aim of this study was to gather information about the pattern of symptoms of depression and anxiety amongst UK Thalidomide survivors. A cross-sectional postal survey of 182 UK Thalidomide survivors, which used Patient Health Questionnaire (PHQ-9) and General Anxiety Disorder Scale (GAD-7) to measure self-reported depression and anxiety, was conducted. Data were first analysed using descriptive statistics. A point-biserial correlation was used to examine whether being unable to work was associated with higher depression and anxiety scores. Prevalence of all levels of depression and anxiety was higher amongst the Thalidomide survivors than the general UK population but broadly similar to other groups of adults with disabling conditions. Being unable to work was associated with higher depression and anxiety scores. More research is needed to understand the relationship between early acquired physical disability and depression, in particular the implications, over the life course, of secondary health problems and changing social roles.

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dePression, ANxiety, and acaDEMImiC performance in COVID- 19: The PANDEMIC study: A cross-sectional survey study

10.21203/rs.3.rs-353928/v1 ◽

2021 ◽

Author(s):

Francisco José Barbosa-Camacho ◽

Olaya Moramay Romero-Limón ◽

Juan Carlos Ibarrola-Peña ◽

Yolanda Lorelei Almanza-Mena ◽

Kevin Josue Pintor-Belmontes ◽

...

Keyword(s):

Anxiety Disorder ◽

Self Concept ◽

Depression And Anxiety ◽

Cross Sectional Survey ◽

Cross Sectional ◽

General Anxiety Disorder ◽

General Anxiety ◽

Scale Scores ◽

Patient Health ◽

Screening Scale

Abstract BackgroundAfter almost nine months of social isolation, the high incidence of depression and anxiety is understandable. However, depression and anxiety can adversely affect the quality of life. One of the biggest challenges in this global pandemic is providing education within public and private academic institutes.MethodsThis study was a cross-sectional survey distributed online from April to June 2020. We used the Patient Health Questionnaire-9 depression screening scale and the General Anxiety Disorder-7 screening scale to identify the presence of mental health disorders such as depression or anxiety in undergraduate and graduate students. We used the Academic Self-Concept Scale to determine whether these disorders altered students' perception of their academic performance.ResultsA total of 610 students answered the survey: 386 female (63.3%) and 224 male (36.7%). Most students (71.5%) had not participated in online courses before. When asked about their class preferences, 581 students (95.2%) preferred to be taught in classes. The average Academic Self-Concept Scale score was 2.76 ± 0.35. The Academic Self-Concept Scale scores were divided into Confidence and Effort categories, and their respective mean scores were 2.71 ± 0.37 and 2.82 ± 0.45. The total mean Patient Health Questionnarie-9 scores were 11.94 ± 6.90, and the mean General Anxiety Disorder-7 score was 10.30 ± 5.66. There were significant effects of the severity of depression and anxiety on the Academic Self-Concept Scale scores (p < 0.001 and p < 0.05, respectively).ConclusionsThe findings suggest that changing from classroom-based teaching to online delivery is not a challenge for students in the normal situation. However, being quarantined can be stressful and frustrating, which may challenge effective learning.Trial registrationThe study protocol was submitted to ClinicalTrials.gov and registered with the identifier: NCT04420416.

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Jordanian ostomates' health problems and self-care ability to manage their intestinal ostomy: a cross-sectional study

Journal of Research in Nursing ◽

10.1177/1744987120941568 ◽

2020 ◽

Vol 25 (8) ◽

pp. 679-696

Author(s):

Rami A Elshatarat ◽

Inas A Ebeid ◽

Khadega A Elhenawy ◽

Zyad T Saleh ◽

Ahmad H Abu Raddaha ◽

...

Keyword(s):

Self Care ◽

Cross Sectional Study ◽

Health Problems ◽

Sectional Study ◽

Cross Sectional ◽

General Anxiety Disorder ◽

General Anxiety ◽

Questionnaire Score ◽

Patient Health ◽

And Training

Background Ostomates have several physical, psychological and social health problems. These problems negatively impact the ostomates' quality of life. Aims This study aims to identify Jordanian ostomates' health problems and their self-care ability to manage their ostomies. Methods This is a cross-sectional study. A convenience sampling method was used to recruit 168 Jordanian patients with intestinal ostomies. A self-report questionnaire was used to collect the data. Results On average, the participants’ physiological ostomy-related problem scores were 8.76 ± 2.37 (out of 13 problems) and the total score of self-care ability to manage their ostomies was 16.56 ± 2.62 (out of 24). About 22% of the participants had ‘moderately severe’ to ‘severe’ depression (nine-item Patient Health Questionnaire score ≥15) and 33.9% had ‘moderate’ to ‘severe’ anxiety (seven-item General Anxiety Disorder questionnaire score ≥10). About half of the participants had exposure to teaching and/or training about ostomy care. About 85% of participants were willing to attend health education and training programmes about ostomy care. There was a significant correlation between high ostomates’ self-care ability to manage their ostomies and a low number of physiological health problems ( r = −0.67, p = 0.04), a low depression (Patient Health Questionnaire 9) score ( r = −0.54, p = 0.039) and a low anxiety (seven-item General Anxiety Disorder questionnaire) score ( r = −0.71, p < 0.027). Conclusions Health teaching and training about intestinal ostomy management, psychosocial support, follow-up assessment and treatment for ostomy-related problems are recommended for all ostomates.

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Prevalence and measurement of anxiety and depression in nurses during COVID pandemic in Nepal

Insights on the Depression and Anxiety ◽

10.29328/journal.ida.1001021 ◽

2020 ◽

Vol 4 (1) ◽

pp. 059-063

Author(s):

Chandra Ayush ◽

Chandra Avinash ◽

Sharma Nabina

Keyword(s):

Mental Health ◽

Rating Scale ◽

Mental Health Problems ◽

Anxiety And Depression ◽

Depression And Anxiety ◽

Cross Sectional ◽

General Anxiety Disorder ◽

General Anxiety ◽

Validated Questionnaire ◽

Hamilton Anxiety Scale

Background: Anxiety and depression are under reported, underdiagnosed mental illness in health worker in Nepal especially during COVID pandemic. The study was carried out as an observational study on nurses in Nepal. In this study we attempted to assess the incidence and impact of depression and anxiety in nurses who are working upfront in different hospitals during this crisis. Objective: The purpose of the study is to assess the prevalence of anxiety and depression among nurses in Nepal during COVID pandemic who are working in various hospitals. Method: A cross-sectional non-probability purposive sampling with observational analysis was carried out and the sample was collected from nurses working in different hospitals. Prevalence of anxiety and depression was assessed using a structured and validated questionnaire. Anxiety was assessed with the Hamilton Anxiety Scale (HAM-A), General Anxiety Disorder Questionnaires (GAD) with a cut-off score for various levels of anxiety while Hamilton Depression Rating Scale (HAM-D) was used to assess depression. Result: The analysis of these different scales revealed that disabling anxiety prevailed at highest (43.6%) in nursing staff according to HAM-A scale. Moderate anxiety also seemed to be higher (> 20%) in GAD questionnaire. Conclusion: This is the first study carried out in Nepal that investigates the mental health of nurses who are working in the frontline in this COVID pandemic situation. The study revealed that our nurses who have given their life in the line are suffering from serious mental health problems.

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Depression and Anxiety in Patients with Rare Diseases during the COVID-19 Pandemic

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18063234 ◽

2021 ◽

Vol 18 (6) ◽

pp. 3234

Author(s):

Juan Carlos Sánchez-García ◽

Jonathan Cortés-Martín ◽

Raquel Rodríguez-Blanque ◽

Ana Eugenia Marín-Jiménez ◽

Maria Montiel-Troya ◽

...

Keyword(s):

Rare Diseases ◽

Population Sample ◽

Population Group ◽

Depression And Anxiety ◽

Online Questionnaire ◽

Cross Sectional ◽

General Anxiety Disorder ◽

General Anxiety ◽

Comprehensive Management ◽

Patient Health

Scientific knowledge on depression and anxiety in patients with rare diseases during the COVID-19 pandemic is scarce; however, it is essential to perform comprehensive management of these patients. The aim of this study was to research how the situation caused by the SARS-CoV-2 pandemic has influenced the lives of patients with rare diseases regarding depression and anxiety. This Spanish study considered a heterogeneous population sample of 86 patients with confirmed diagnosis of different rare diseases. Participants took part in a cross-sectional online study by completing specific questionnaires on the study topic. Depression was measured using the Patient Health Questionnaire (PHQ-9), and the General Anxiety Disorder Scale (GAD-7) was used for evaluating anxiety. Data collection through an online questionnaire allowed for a greater population scope and therefore the inclusion patients of other nationalities in the study sample. Finally, as a general result, this study found that, in the face of the pandemic, anxiety and depression remained at a higher level in this group than in the general population, making these patients a vulnerable population group.

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Psychological Effects of the COVID-19 Pandemic on Hungarian Adults

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17249565 ◽

2020 ◽

Vol 17 (24) ◽

pp. 9565

Author(s):

Csanád Szabó ◽

Judit Pukánszky ◽

Lajos Kemény

Keyword(s):

Perceived Stress ◽

Psychological Effects ◽

Measuring Instruments ◽

Online Questionnaire ◽

Cross Sectional ◽

Psychological Variables ◽

Ways Of Coping ◽

General Anxiety Disorder ◽

General Anxiety ◽

Patient Health

We aimed to explore psychological effects of the coronavirus pandemic on Hungarian adults in the time of the national quarantine situation in May 2020.We conducted a cross-sectional observational study with the use of an anonymous online questionnaire that consisted of 65 items. The following measuring instruments were used: Perceived Stress Scale (PSS-10); The General Anxiety Disorder Assessment (GAD)-2; The Patient Health Questionnaire (PHQ)-2; European Quality of Life Visual Analogue Scale (EQ-VAS); Self-administered inventory of complaints (Hungarian questionnaire); Shortened (Hungarian) version of the Ways of Coping Questionnaire; 2 open-ended questions to examine the participants’ mood and ways of coping during the pandemic. The data of 431 participants were analyzed, their average age was 47.53 ± 11.66 years, and the percentage of females was 90%. The mean of participants’ scores were the following: 19.34 ± 7.97 for perceived stress, 73.05 ± 21.73 for health status, and 8.68 ± 4.65 for neurotic complaints. Thirty-four and one-tenth percent of participants were depressed, 36.2% were anxious, and they tended to use problem-focused coping strategies more frequently than emotion-focused ones. We found significant correlations between all of the seven examined psychological variables. Our results highlight the importance of stress management in the psychological support of healthy adults in quarantine situation caused by the coronavirus pandemic.

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Prevalence of Stress and Associated Factors among Regular Students at Debre Birhan Governmental and Nongovernmental Health Science Colleges North Showa Zone, Amhara Region, Ethiopia 2016

Psychiatry Journal ◽

10.1155/2018/7534937 ◽

2018 ◽

Vol 2018 ◽

pp. 1-7 ◽

Cited By ~ 4

Author(s):

Ayele Mamo Abebe ◽

Yilma Girma Kebede ◽

Fikir Mengistu

Keyword(s):

Mental Health Problems ◽

Health Problems ◽

Health Science ◽

P Value ◽

Depression And Anxiety ◽

Amhara Region ◽

Cross Sectional ◽

Science College ◽

Regular Students ◽

Debre Birhan

Background. Stress is very common among medical students across the globe with the prevalence of 80%. In Ethiopia, the prevalence is 47.7% among college students. Unless it is managed early, it leads to deterioration of academic performance and overall dissatisfaction with life and different serious health problems including anxiety, depression, and suicide. The objective of this study is to assess the prevalence of academic related stress among Debre Birhan governmental and nongovernmental health science college regular students 2015/16. Method. A cross-sectional study was conducted on a sample of 422 health science students selected by stratified proportional random sampling at Debre Birhan governmental and nongovernmental health science colleges in North Shewa zone, Amhara region, Ethiopia in 2016. Data was collected using the Depression Anxiety Stress Scaling (DASS-21). The level of significance of association for multivariable was determined at P value <0.05. Result. Prevalence of stress among Debre Birhan governmental and nongovernmental health science college regular students is 4.1%. There is a significant association between stress and sex AOR = 8.525 (1.023, 71.077), fear of examination AOR = 5.096 (1.183, 21.96), living in uncomfortable environment AOR = 14.86 (3.84, 57.515), and perceived present illness AOR = .030 (0.003, 0.286). Depression and anxiety were also seen among 19.7% and 23.6%, respectively. Conclusion. According to this study, the prevalence of stress among governmental and nongovernmental health science college regular students is not high. However, depression and anxiety were found to be higher than stress and they need immediate management plan. Colleges had better prepared simple screening tool and support students to prevent stress before they cause severe mental health problems.

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Help Seeking and Access to Primary Care for People from “Hard-to-Reach” Groups with Common Mental Health Problems

International Journal of Family Medicine ◽

10.1155/2011/490634 ◽

2011 ◽

Vol 2011 ◽

pp. 1-10 ◽

Cited By ~ 18

Author(s):

K. Bristow ◽

S. Edwards ◽

E. Funnel ◽

L. Fisher ◽

L. Gask ◽

...

Keyword(s):

Mental Health ◽

Primary Care ◽

Help Seeking ◽

Mental Health Problems ◽

Health Problems ◽

Structured Interviews ◽

Care Givers ◽

Common Mental Health Problems ◽

Access To Primary Care ◽

The Uk

Background. In the UK, most people with mental health problems are managed in primary care. However, many individuals in need of help are not able to access care, either because it is not available, or because the individual's interaction with care-givers deters or diverts help-seeking. Aims. To understand the experience of seeking care for distress from the perspective of potential patients from “hard-to-reach” groups. Methods. A qualitative study using semi-structured interviews, analysed using a thematic framework. Results. Access to primary care is problematic in four main areas: how distress is conceptualised by individuals, the decision to seek help, barriers to help-seeking, and navigating and negotiating services. Conclusion. There are complex reasons why people from “hard-to-reach” groups may not conceptualise their distress as a biomedical problem. In addition, there are particular barriers to accessing primary care when distress is recognised by the person and help-seeking is attempted. We suggest how primary care could be more accessible to people from “hard-to-reach” groups including the need to offer a flexible, non-biomedical response to distress.

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Assessment of Common Mental Health Problems among General Population

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i36b31970 ◽

2021 ◽

pp. 210-217

Author(s):

Dharti Meshram ◽

Pooja Kasturkar

Keyword(s):

Mental Health ◽

General Population ◽

Mental Health Problems ◽

Global Mental Health ◽

Behavioral Problem ◽

Sampling Technique ◽

Health Problems ◽

Demographic Variables ◽

Cross Sectional ◽

Common Mental Health Problems

Background: Around 7.3 per cent of the global disease burden was due to mental and behavioral problem. The majority of the load is correlated with unipolar depressive condition and certain conditions of mental health, including depression, anxiety, eating disorder, and substance use. Roughly 450 million persons are currently suffering from these disorders, and It is assessed that at some stage in their lifetime, one-four individuals in the world will be affected by mental health conditions. Mental health condition rank among the world's principal reasons of illness or impairment. Persons with most depressing condition or schizophrenia were 40 to 60 per cent more likely than the general population to die prematurely. Aim: To identify common mental health problems among general population. Objective: This study is planned with the objective. 1. To assess common mental health problems among general population. 2. To compare the common mental health problems among rural and urban general population. 3. To associate common mental problems, score among general population with their demographic variables. Methodology: lt is community based cross-sectional study. Sample will be general population i.e., Male and Female of Nalwadi, Arvi Naka wardha city will be involved in this study. Sample will be selected for study as per inclusion criteria and sampling technique will be N on-Probability y convenient sampling technique. Data will be collected by demographic variables of participants Global mental health assessment Marathi tool will be distributed for assessing mental health problem need 20 min for each participant. Conclusion: The conclusion will e drawn from the statistical analysis.

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Prevalence of Mental Health Problems and Its Associated Factors Among Recovered COVID-19 Patients During the Pandemic: A Single-Center Study

Frontiers in Psychiatry ◽

10.3389/fpsyt.2021.602244 ◽

2021 ◽

Vol 12 ◽

Author(s):

Mojgan Khademi ◽

Roya Vaziri-Harami ◽

Jamal Shams

Keyword(s):

Mental Health ◽

Associated Factors ◽

Mental Health Problems ◽

Female Gender ◽

Health Problems ◽

Post Traumatic Stress ◽

Cross Sectional ◽

Care Workers ◽

Patient Health ◽

History Of

Introduction: The coronavirus disease 2019 (COVID-19), is profoundly affecting the mental health status. Although the burden of mental health problems has been reported in the general population and health care workers, little is known about the prevalence of mental health disorders among recovered COVID-19 patients and their associated factors.Methods: A cross-sectional telephonic-study of recovered COVID-19 patients with and without a history of hospitalization was conducted from April 20 to June 20, 2020, in Tehran, Iran. We assessed the anxiety symptoms, depression, and post-traumatic stress disorder (PTSD) among participants, using the Patient Health Questionnaire (PHQ-4) and PTSD checklist for DSM-5 (PCL-5). Logistic regression analyses were used to explore the risk factors associated with mental health problems.Results: A total of 602 individuals with a mean age of 53.2 years (SD: 14.7), completed the study. The rates of mental health symptoms among the respondents were 5.8% (95% CI: 4.2–7.8%) for anxiety, 5.0% (95% CI: 3.5–7.0%) for depression, and 3.8% (95% CI: 2.3–5.3%) for PTSD disorders. Moreover, being younger than 50 years and female gender was significantly associated with a higher probability of reporting anxiety (p < 0.01), and depression (p < 0.001 for being younger than 50 years, p < 0.02 for female gender).Conclusions: The current study indicated that patients with COVID-19 presented features of anxiety, depression, and PTSD. These results may help implement appropriate mental health intervention policies for those at risk and minimize the mental health consequences of the COVID-19.

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Disrupted Rhythms of Life, Work and Entertainment Behaviours and Their Associations with Mental Health Problems under the Stress of COVID-19 Epidemic: A Survey in 5854 Chinese People with Different Backgrounds

10.21203/rs.3.rs-27400/v1 ◽

2020 ◽

Author(s):

Min Yang ◽

Ping He ◽

Xiaoming Xu ◽

Jing Wang ◽

Yanjun Wang ◽

...

Keyword(s):

Mental Health ◽

Health Status ◽

Mental Health Problems ◽

Health Problems ◽

Annual Income ◽

Depression And Anxiety ◽

Related Factors ◽

Cross Sectional ◽

Psychosomatic Diseases ◽

Life Work

Abstract BACKGROUND and OBJECTIVE The rhythms of life, work and entertainment behaviours are considered as the external behavioural manifestations of biological rhythm.To evaluate the distinctive disrupted rhythms of behaviours and their associations with mental health problems in people with different backgrounds under the stress of COVID-19 epidemic.SUBJECTS AND METHODS A cross-sectional study was conducted from 10-17 March 2020 under the stress of COVID-19 epidemic.A structured e-questionnaire containing general information,rhythm scale(subscale1 for life-work rhythms and subscale2 for entertainment rhythm) and Zung's self-rating depression and anxiety scale(SDS and SAS) were filled and the data were analysed.RESULTS Overall 5854 participants were included.Significant differences were found in rhythm, SDS and SAS scores among people with different backgrounds (all P<0.05). Subjects with female gender and poor health status were mostly suffered from disrupted rhythms of life- work-entertainment behaviours, combined with depression and anxiety. Nurses and subjects being divorced or with chronic disease with psychosomatic diseases were mostly suffered from disrupted rhythms of life-work behaviours, combined with depression and anxiety. Subjects with aged 26-30 years, or annual income of 50,000-100,000CY were mostly suffered from disrupted rhythms of life-work combined with depression. Subjects with income over 300,000CY were mostly suffered from disrupted rhythm of entertainment combined with anxiety.The prevalence rates of depression and anxiety in people with the high-scores of rhythm disruption increased by 34.50% and 47.16%, respectively, compared with those with low-scores.People with the high-scores of rhythm disruption had higher SDS and SAS scores, compared to those with low scores (all P<0.001). The independent related factors of disrupted rhythms included gender,age,marital status, health status,annual income and chronic diseases with psychosomatic diseases using logistic regression.The disrupted rhythms of life and work behaviours was positively correlated with both SDS and SAS scores.CONCLUSIONS The disrupted rhythms of life, work and entertainment behaviours were closely associated with mental health problems.The disrupted rhythms of behaviours are frequent and fluxible,triggering more severe mental health problems under the stress of COVID-19 epidemic.The physicians should be aware of their importance when evaluating their interviewees or patients’ mental health and achieving maximization of therapeutic efficacy by integrating the intervention of circadian rhythm and its behaviour.

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