scholarly journals Weathering Behaviour of Cunninghamia lanceolata (Lamb.) Hook. under Natural Conditions

Forests ◽  
2020 ◽  
Vol 11 (12) ◽  
pp. 1326
Author(s):  
Xinjie Cui ◽  
Junji Matsumura
Keyword(s):  
Chinese Fir ◽  
Cunninghamia Lanceolata ◽  
Natural Conditions ◽  
Structural Degradation ◽  
Before And After ◽  
Wood Utilization ◽  
Pre Treatment ◽  
Wood Surfaces ◽  
Weathering Behaviour

Information on the weathering behaviour of Cunninghamia lanceolata (Lamb.) Hook. is needed to provide references for wood weatherproof pre-treatment and to improve wood utilization. Therefore, this study was conducted to understand the variation in the intrinsic weathering behaviour of Cunninghamia lanceolata (Chinese fir) under natural conditions. Wood samples from 15 Cunninghamia lanceolata trees aged 26–30 years old were used. The structural degradation and discoloration of wood surfaces before and after exposure were compared. The results show that the weathering behaviour of wood was weakened from heartwood to sapwood and enhanced from the bottom to the top. This study provided information for weatherability research and improved wood utilization of Cunninghamia lanceolata.

Cytoprotective Effect of Tocotrienol-Rich Fraction and α-Tocopherol Vitamin E Isoforms Against Glutamate-Induced Cell Death in Neuronal Cells

2014 ◽  
Vol 84 (3-4) ◽  
pp. 0140-0151 ◽  
Author(s):  
Thilaga Rati Selvaraju ◽  
Huzwah Khaza’ai ◽  
Sharmili Vidyadaran ◽  
Mohd Sokhini Abd Mutalib ◽  
Vasudevan Ramachandran ◽  
...  
Keyword(s):  
Vitamin E ◽  
Cell Viability ◽  
Neuronal Cells ◽  
Positive Control ◽  
Post Treatment ◽  
Mitochondrial Activity ◽  
Before And After ◽  
Pre Treatment ◽  
Tocotrienol Rich Fraction ◽  
Major Mediator

Glutamate is the major mediator of excitatory signals in the mammalian central nervous system. Extreme amounts of glutamate in the extracellular spaces can lead to numerous neurodegenerative diseases. We aimed to clarify the potential of the following vitamin E isomers, tocotrienol-rich fraction (TRF) and α-tocopherol (α-TCP), as potent neuroprotective agents against glutamate-induced injury in neuronal SK-N-SH cells. Cells were treated before and after glutamate injury (pre- and post-treatment, respectively) with 100 - 300 ng/ml TRF/α-TCP. Exposure to 120 mM glutamate significantly reduced cell viability to 76 % and 79 % in the pre- and post-treatment studies, respectively; however, pre- and post-treatment with TRF/α-TCP attenuated the cytotoxic effect of glutamate. Compared to the positive control (glutamate-injured cells not treated with TRF/α-TCP), pre-treatment with 100, 200, and 300 ng/ml TRF significantly improved cell viability following glutamate injury to 95.2 %, 95.0 %, and 95.6 %, respectively (p < 0.05).The isomers not only conferred neuroprotection by enhancing mitochondrial activity and depleting free radical production, but also increased cell viability and recovery upon glutamate insult. Our results suggest that vitamin E has potent antioxidant potential for protecting against glutamate injury and recovering glutamate-injured neuronal cells. Our findings also indicate that both TRF and α-TCP could play key roles as anti-apoptotic agents with neuroprotective properties.

scholarly journals Transcriptomic analysis identifies differences in gene expression in actinic keratoses after treatment with imiquimod and between responders and non responders

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Megan H. Trager ◽  
Emanuelle Rizk ◽  
Sharon Rose ◽  
Kuixi Zhu ◽  
Branden Lau ◽  
...  
Keyword(s):  
Gene Expression ◽  
Squamous Cell Carcinoma ◽  
Distinct Pattern ◽  
Study Endpoint ◽  
Inflammatory Gene Expression ◽  
Immune Modulators ◽  
Actinic Keratoses ◽  
Before And After ◽  
Pre Treatment

AbstractThe presence of actinic keratoses (AKs) increases a patient’s risk of developing squamous cell carcinoma by greater than six-fold. We evaluated the effect of topical treatment with imiquimod on the tumor microenvironment by measuring transcriptomic differences in AKs before and after treatment with imiquimod 3.75%. Biopsies were collected prospectively from 21 patients and examined histologically. RNA was extracted and transcriptomic analyses of 788 genes were performed using the nanoString assay. Imiquimod decreased number of AKs by study endpoint at week 14 (p < 0.0001). Post-imiquimod therapy, levels of CDK1, CXCL13, IL1B, GADPH, TTK, ILF3, EWSR1, BIRC5, PLAUR, ISG20, and C1QBP were significantly lower (adjusted p < 0.05). Complete responders (CR) exhibited a distinct pattern of inflammatory gene expression pre-treatment relative to incomplete responders (IR), with alterations in 15 inflammatory pathways (p < 0.05) reflecting differential expression of 103 genes (p < 0.05). Presence of adverse effects was associated with improved treatment response. Differences in gene expression were found between pre-treatment samples in CR versus IR, suggesting that higher levels of inflammation pre-treament may play a part in regression of AKs. Further characterization of the immune micro-environment in AKs may help develop biomarkers predictive of response to topical immune modulators and may guide therapy.

Age-dependent microRNAs in regulation of vascular cambium activity in Chinese fir (Cunninghamia lanceolata)

Trees ◽  
2021 ◽  
Author(s):  
Guijun Liu ◽  
Xian Xue ◽  
Jinling Feng ◽  
Dechang Cao ◽  
Jinxing Lin ◽  
...  
Keyword(s):  
Chinese Fir ◽  
Cunninghamia Lanceolata ◽  
Vascular Cambium ◽  
Age Dependent ◽  
Cambium Activity

Effect of Carbon Pre-Treatment on Pd Dispersion in Synthesis of Pd/C Catalyst

2014 ◽  
Vol 804 ◽  
pp. 149-152 ◽  
Author(s):  
Ji Sun Kim ◽  
Jae Ho Baek ◽  
Myung Hwan Kim ◽  
Seong Soo Hong ◽  
Man Sig Lee
Keyword(s):  
Surface Area ◽  
Nitrogen Adsorption ◽  
Area Ratio ◽  
High Dispersion ◽  
Co Chemisorption ◽  
Pd Dispersion ◽  
Before And After ◽  
Pre Treatment ◽  
Treated Carbon ◽  
Adsorption Desorption

In this study, we confirmed effect of carbon pre-treatment on Pd dispersion in synthesis of Pd/C catalyst. Physical characteristics on the surface of before and after pre-treated carbon were analyzed by nitrogen adsorption-desorption analysis. The dispersion and size of Pd particles were analyzed by XRD, FE-TEM and CO-chemisorption. After pre-treatment, surface area of carbon were decreased. And mesopore area ratio were increased with decreasing micropore area ratio. In the case of pre-treated carbon, we confirmed high dispersion of Pd particles.

Colour stability of surface finishes on thermally modified beech wood

2021 ◽  
Vol 114 ◽  
pp. 116-124
Author(s):  
Gabriela Slabejová ◽  
MÁRIA ŠMIDRIAKOVÁ
Keyword(s):  
Surface Finish ◽  
Beech Wood ◽  
Surface Finishing ◽  
Colour Stability ◽  
Colour Difference ◽  
Surface Finishes ◽  
Before And After ◽  
Thermally Modified Wood ◽  
Wood Surfaces ◽  
Modified Wood

Colour stability of surface finishes on thermally modified beech wood. The paper deals with the influence of the type of transparent surface finish on the change of colour of the surfaces of native beech wood and thermally modified wood. At the same time, the colour stability of three surface finishes on the surfaces of native and thermally modified beech wood was monitored. Beech wood was thermally modified at temperature of 125 °C for 6 hours. The thermal treatment was performed in a pressure autoclave APDZ 240, by the company Sundermann s.r.o in Banská Štiavnica. Three various types of surface finishes (synthetic, wax-oil, water-based) were applied onto the wood surfaces. The colour of the surfaces of native wood and thermally modified wood was measured in the system CIELab before and after surface finishing; the coordinates L*, a*, b*, C*ab and h*ab were measured. From the coordinates measured before and after surface finishing, the differences were calculated and then the colour difference ∆E* was calculated. Subsequently, the test specimens with the surface finishes were exposed to natural sunlight, behind glass in the interior for 60 days. The surface colour was measured at specified time of the exposure (10, 20, 30, 60 days). The results showed that the colour of the wood surfaces changed after application of the individual surface finishes; and the colour difference reached a change visible with a medium quality filter up to a high colour difference. The wax-oil surface finish caused a high colour difference on native wood and on thermally modified wood as well. On native beech wood, the lowest colour difference after exposure to sunlight was noticeable on the synthetic surface finish. On the surface of wood thermally modified, after exposure to sunlight, the lowest colour difference was noticeable on the surface with no surface finish.

Fabrication and characterization of composite MoS2-TiO2 coating material

2021 ◽  
pp. 095440622110157
Author(s):  
Avinash V Borgaonkar ◽  
Ismail Syed ◽  
Shirish H Sonawane
Keyword(s):  
Bond Strength ◽  
Treatment Method ◽  
Optical Microscope ◽  
Scratch Resistance ◽  
Substrate Material ◽  
Coating Film ◽  
Tribological Behaviour ◽  
Molybdenum Disulphide ◽  
Before And After ◽  
Pre Treatment

Molybdenum disulphide (MoS2) is a popularly used solid lubricant in various applications due to its superior tribological behaviour. However, it possesses poor wear resistance which requires further improvement. In the present study efforts have been made to enhance the tribological properties of pure MoS2 coating film by doping TiO2 nanoparticles as a reinforcement material. The Manganese phosphating is selected as a pre-treatment method to improve the bond strength between coating and substrate. The coating is bonded with the substrate material employing sodium silicate as a binder. The effects of wt. % of TiO2 onto the mechanical properties of composite MoS2-TiO2 coating such as hardness and bond strength have been studied. In addition coating microstructure before and after experimental test was studied using optical microscope and scanning electron microscope. It was also found that with increase in wt. % addition of TiO2 upto 15% into MoS2 base matrix, the hardness of coating increases proportionally. Beyond 15 wt. % addition of TiO2, the coating becomes brittle in nature. This leads to reduction in the scratch resistance.

Comprehensive DNA methylation-transcriptome profiles association analysis During the Treatment of Acute Myelocytic Leukemia

2021 ◽  
Vol 27 ◽  
Author(s):  
Jun Wu ◽  
Ming-Zhu Song ◽  
Li-Jun Deng ◽  
Qian-Ling Ye
Keyword(s):  
Dna Methylation ◽  
Association Analysis ◽  
Stem Cell Differentiation ◽  
The Cancer Genome Atlas ◽  
Acute Myelocytic Leukemia ◽  
Myelocytic Leukemia ◽  
Before And After ◽  
Pre Treatment ◽  
Population Maintenance ◽  
Therapy Strategies

Background: Epigenetic modifications have recently attracted much attention in the study of the biological mechanisms of acute myelocytic leukemia (AML) for therapy and prognosis. However, studies on DNA methylation changes during AML treatment are limited. Objective: The comprehensive DNA methylation-transcriptome profiles association analysis in this study aimed to establish whole-genome DNA methylation profiles and explore DNA methylation-related genes and their potential functions before and after treatment. And more appropriate biomarkers are expected to be identified for therapy strategies in AML. Method: Illumina 450K and RNA-Seq data were obtained from The Cancer Genome Atlas. We performed comprehensive DNA methylation-transcriptome profiles association analysis, pathway analysis, correlation analysis, and survival analyses. The StarBase database was utilized to predict interactions between lncRNAs, miRNAs and target mRNAs. Results: In total, 1592 distinct CpG sites and 2419 different expression transcripts were identified between pre-treatment and post-treatment AML. The significantly enriched functions of methylated genes were stem cell differentiation, cell population maintenance, and cell development. The expression of UGT3A2, MOG, and VSTM1 was correlated with DNA methylation levels (r2>0.5). Lastly, we identified 4 lncRNAs, 9 miRNAs and 142 mRNAs to construct a lncRNA-miRNA-mRNA ceRNA network. Conclusion: Our results revealed that DNA methylation was altered before and after treatment. Alterations in DNA methylation affected target gene expression and participated in the key biological processes of AML. Therefore, ceRNA networks may provide further insight into the study of favorable therapeutic markers in AML.

Genetic parameters and genotype–environment interactions of Chinese fir (Cunninghamia lanceolata) in Fujian Province

2014 ◽  
Vol 44 (6) ◽  
pp. 582-592 ◽  
Author(s):  
Liming Bian ◽  
Jisen Shi ◽  
Renhua Zheng ◽  
Jinhui Chen ◽  
Harry X. Wu
Keyword(s):  
Genetic Parameters ◽  
Breeding Strategy ◽  
Chinese Fir ◽  
Breeding Program ◽  
Cunninghamia Lanceolata ◽  
Environment Interaction ◽  
Fujian Province ◽  
The Third ◽  
Genotype Environment Interaction ◽  
Sib Families

Chinese fir (Cunninghamia lanceolata (Lamb.) Hook) is the most commercially important conifer in China, and the Nanjing Forestry University – Fujian Province Chinese fir Cooperation (NJFU – Fujian Cooperation) breeding program has advanced it into the third cycle of selection and breeding. In this paper, we estimated genetic parameters from four sites for 80 half-sib families and summarized previous estimates of genetic parameters in Chinese fir with an objective to propose optimal breeding strategy. Heritability averaged 0.20 and 0.14 for height and diameter at breast height (DBH), respectively, for the four sites. A significant genotype–environment interaction (G × E) for growth was also observed among the four sites, with the greatest interactions between a marginal site and the three central sites in the Fujian Province Chinese fir plantation region. The average estimated type-B genetic correlation between the marginal site and the three central sites was 0.08 for height and –0.09 for DBH. However, the highly productive families were among the most stable across the four sites. The results from this study in combination with summarized genetic parameters from literature were used to discuss and propose an optimal breeding strategy for the third generation of the breeding program for Chinese firs in Fujian Province.

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