E-Beam Cross-Linking of Complex Hydrogels Formulation: The Influence of Poly(Ethylene Oxide) Concentration on the Hydrogel Properties

In the present study, we report on the complex hydrogels formulations based on collagen-poly(vinyl pyrrolidone) (PVP)-poly(ethylene oxide) (PEO) cross-linked by e-beam irradiation in an aqueous polymeric solution, aiming to investigate the influence of different PEO concentrations on the hydrogel properties. The hydrogel networks’ structure and their composition were investigated using equilibrium swelling degree, complex rheological analysis, and FT-IR spectroscopy. Rheological analysis was performed to determine the elastic (G′) and viscous (G″) moduli, the average molecular weight between cross-linking points (Mc), cross-link density (Ve), and the mesh size (ξ). The effect of the PEO concentration on the properties of the hydrogel was investigated as well. Depending on the PEO concentration added in their composition, the hydrogels swelling degree depends on the absorbed dose, being lower at low PEO concentrations. All hydrogel formulations showed higher G′ values (9.8 kPa) compared to G″ values (0.2 kPa), which shows that the hydrogels have a predominantly elastic behavior. They presented stability greater than 72 h in physiological pH buffers and reached equilibrium after 25 h. The Mc parameter is strongly dependent on the PEO concentration and the absorbed dose for all hydrogel compositions. The cross-linking density increased with the absorbed dose.

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The Structure of Radiation Cross-Linked Poly (ethylene oxide) Gels

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100064438 ◽

1971 ◽

Vol 29 ◽

pp. 76-77

Author(s):

C. E. Cluthe ◽

G. G. Cocks

Keyword(s):

Molecular Weight ◽

Ethylene Oxide ◽

Parallel Plate ◽

Average Molecular Weight ◽

Radical Reaction ◽

Free Radical Reaction ◽

Nitrogen Gas ◽

Poly Ethylene Oxide ◽

Poly Ethylene ◽

Initial Viscosity

Aqueous solutions of a 1 weight-per cent poly (ethylene oxide) (PEO) were degassed under vacuum, transferred to a parallel plate viscometer under a nitrogen gas blanket, and exposed to Co60 gamma radiation. The Co60 source was rated at 4000 curies, and the dose ratewas 3.8x105 rads/hr. The poly (ethylene oxide) employed in the irradiations had an initial viscosity average molecular weight of 2.1 x 106.The solutions were gelled by a free radical reaction with dosages ranging from 5x104 rads to 4.8x106 rads.

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Effect of Molecular Architecture on Associating Behavior of Star-Like Amphiphilic Polymers Consisting of Plural Poly(ethylene oxide) and One Alkyl Chain

Polymers ◽

10.3390/polym13030460 ◽

2021 ◽

Vol 13 (3) ◽

pp. 460

Author(s):

Daisuke Kugimoto ◽

Aoi Taniguchi ◽

Masaki Kinoshita ◽

Isamu Akiba

Keyword(s):

Ethylene Oxide ◽

Average Molecular Weight ◽

Amphiphilic Polymers ◽

Hydrophobic Core ◽

Molecular Architecture ◽

Polymer Micelles ◽

The Core ◽

X Ray Scattering ◽

Poly Ethylene Oxide ◽

Poly Ethylene

Associating behavior of star-like amphiphilic polymers consisting of two or three poly(ethylene oxide) (PEO) chains and one stearyl chain (C18) was investigated. Although the aggregation number (Nagg) of linear analogue of amphiphilic polymers monotonically decreased with increasing number-average molecular weight of PEO (Mn,PEO), the Nagg of micelles of star-like amphiphilic polymers with Mn,PEO = 550 g/mol was smaller than that with Mn,PEO = 750 g/mol, whereas that with Mn,PEO ≥ 750 g/mol showed general Mn,PEO dependence. Small-angle X-ray scattering analyses revealed that the occupied area of one PEO chain on the interface between hydrophobic core and corona layer in the micelles of star-like polymers was much narrower than that in the linear amphiphilic polymers. This result indica ted the PEO chains of star-like polymers partially took unfavorable conformation near the core–corona interface in polymer micelles. The effect of local conformation of PEO chains near the interface on the associating behavior became significant as Mn,PEO decreased. Therefore, in polymer micelles of star-like amphiphilic polymers containing PEO with Mn,PEO = 550 g/mol, the enlargement of occupied area of PEO on the core–corona interface should be caused to avoid the formation of unfavorable conformations of partial PEO chains, resulting in a decrease in Naggs.

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Cross-linking network based on Poly(ethylene oxide): Solid polymer electrolyte for room temperature lithium battery

Journal of Power Sources ◽

10.1016/j.jpowsour.2019.02.090 ◽

2019 ◽

Vol 420 ◽

pp. 63-72 ◽

Cited By ~ 35

Author(s):

Yuhang Zhang ◽

Wei Lu ◽

Lina Cong ◽

Jia Liu ◽

Liqun Sun ◽

...

Keyword(s):

Ethylene Oxide ◽

Polymer Electrolyte ◽

Solid Polymer Electrolyte ◽

Lithium Battery ◽

Room Temperature ◽

Solid Polymer ◽

Cross Linking ◽

Poly Ethylene Oxide ◽

Poly Ethylene

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Strong poly(ethylene oxide) based gel adhesives via oxime cross-linking

Acta Biomaterialia ◽

10.1016/j.actbio.2015.10.018 ◽

2016 ◽

Vol 29 ◽

pp. 206-214 ◽

Cited By ~ 15

Author(s):

Smita Ghosh ◽

Jaydee D. Cabral ◽

Lyall R. Hanton ◽

Stephen C. Moratti

Keyword(s):

Ethylene Oxide ◽

Cross Linking ◽

Poly Ethylene Oxide ◽

Poly Ethylene

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Investigation on Structural and Dielectric Properties of Silica Nanoparticles Incorporated Poly(Ethylene Oxide)/Poly(Vinyl Pyrrolidone) Blend Matrix Based Nanocomposites

Journal of Inorganic and Organometallic Polymers and Materials ◽

10.1007/s10904-018-1034-1 ◽

2018 ◽

Vol 29 (2) ◽

pp. 592-607 ◽

Cited By ~ 12

Author(s):

Shobhna Choudhary ◽

R. J. Sengwa

Keyword(s):

Dielectric Properties ◽

Ethylene Oxide ◽

Silica Nanoparticles ◽

Vinyl Pyrrolidone ◽

Poly Ethylene Oxide ◽

Poly Ethylene ◽

Poly Vinyl Pyrrolidone

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Fabrication and Properties of High-Content Keratin/Poly (Ethylene Oxide) Blend Nanofibers Using Two-Step Cross-Linking Process

Journal of Nanomaterials ◽

10.1155/2015/803937 ◽

2015 ◽

Vol 2015 ◽

pp. 1-7 ◽

Cited By ~ 3

Author(s):

Yong Liu ◽

Xia Yu ◽

Jia Li ◽

Jie Fan ◽

Meng Wang ◽

...

Keyword(s):

Ethylene Oxide ◽

Average Diameter ◽

Diglycidyl Ether ◽

Cross Linking ◽

Electrospun Fibers ◽

Hydrophobic Property ◽

Poly Ethylene Oxide ◽

Cross Linker ◽

Poly Ethylene ◽

Nanofiber Mats

High-content keratin/poly (ethylene oxide) (PEO) (90/10) blend nanofibers were prepared by electrospinning combined with a two-step cross-linking process. The keratin/PEO aqueous solution was firstly mixed with ethylene glycol diglycidyl ether (EGDE) as cross-linker and then electrospun into nanofibers. The resulting nanofibrous mats were cross-linked with EGDE vapor to decrease the solubility of nanofibers in water. The morphologies and properties of electrospun fibers were investigated by SEM, FTIR, TG, XRD, and contact angle testing, respectively. The results showed that the morphologies of nanofibers were uniform at the fiber average diameter of 300 nm with negligible bead defects by adding EGDE to keratin/PEO solutions. The cross-linking results showed that EGDE vapor could improve the hydrophobic property of blended nanofibers. The crystallinity of the keratin/PEO blend nanofiber mat increased from 13.14% for the uncross-linked sample to 21.54% and 35.15% for the first cross-linked and second cross-linked samples, respectively. Free defect nanofiber mats with high keratin content producing from this two-step cross-linking process are particularly promising for tissue engineering and cell-seeded scaffold.

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