scholarly journals The Association between Lead and Attention-Deficit/Hyperactivity Disorder: A Systematic Review

Author(s):  
Gabriele Donzelli ◽  
Annalaura Carducci ◽  
Agustin Llopis-Gonzalez ◽  
Marco Verani ◽  
Agustin Llopis-Morales ◽  
...  

The etiology of Attention-Deficit/Hyperactivity Disorder (ADHD) is complex and multifactorial. Although the development of ADHD symptoms remains to be elucidated, in recent years, epigenetic processes have emerged as candidate mechanisms. Lead is one of the most dangerous environmental pollutants, and it is suspected to be associated with ADHD. The aim of the present study was to review the epidemiological literature currently available on the relation between lead exposure and the diagnosis of ADHD. The PubMed and EMBASE databases were searched from 1 July 2018 up to 31 July 2018. The authors included observational studies (cohort, case–control and cross-sectional studies) published in English carried out on children within the last 5 years, measuring lead exposure and health outcomes related to ADHD. Seventeen studies met the inclusion criteria: 5 of these studies found no association between lead exposure and ADHD whereas the remaining 12 studies showed positive associations, even though not all of them were homogeneous in terms of exposure periods considered or ADHD diagnosis. To conclude, the evidence from the studies allowed us to establish that there is an association between lead and ADHD and that even low levels of lead raise the risk. However, there is still a lack of longitudinal studies about the relationship between lead exposure and the development of ADHD. Given the potential importance for public health, further research that includes the entire potential risk factors for ADHD in children must be encouraged.

2021 ◽  
Author(s):  
Yu-Chieh Chuang ◽  
Ching-Yun Wang ◽  
Wei-Lieh Huang ◽  
Liang-Jen Wang ◽  
Ho-Chang Kuo ◽  
...  

Abstract Studies in the field of neuroscience and psychology have hypothesized that a causal association exists between atopic diseases and attention-deficit/hyperactivity disorder (ADHD). Previous systematic reviews and meta-analyses have reported a higher risk of ADHD in children with atopic diseases; however, the relationship between ADHD symptoms and atopic diseases remains unclear. We systematically reviewed observational cross-sectional and longitudinal studies to investigate the relationship between atopic diseases and ADHD symptom severity (hyperactivity/impulsivity and inattention). The majority of studies showed a statistically significant association between atopic diseases and both ADHD symptoms, with substantial heterogeneity in the outcome of hyperactivity/impulsivity. Inconsistent results were observed in the subgroup analysis of different exclusion criteria for patients with ADHD. Our study indicated that atopic diseases not only increase the risk of ADHD but also are associated with ADHD symptom severity. This association was even observed in children with subthreshold ADHD, indicating that atopic diseases play a role in the spectrum of ADHD symptom severity. Trial registration: This study was registered on PROSPERO (registration ID: CRD42020213219).


2021 ◽  
Vol 30 (2) ◽  
pp. 98-107
Author(s):  
Maryam Koosha ◽  
◽  
Samira Naghipour ◽  
Mahnaz Fallahi Khesht Masjedi ◽  
◽  
...  

Background: Attention-deficit/ hyperactivity disorder (ADHD) is one of the most common psychiatric disorders in children and adolescents. Parents of these youth experience more parenting stress. Emotional Intelligence (EI) has a very close relationship with mental health. Objective: This study aimed to investigate the relationship between EI and parenting stress in mothers of ADHD youth. Methods: This cross-sectional study was conducted on 136 mothers of ADHD children and adolescents under treatment in the Gil specialized consulting center of Rasht City. Demographic questionnaire, PSI-SF parenting stress questionnaire, and Shearing emotional intelligence questionnaire were used to evaluate the participants. Comorbidities extracted from the patient files, based on the diagnosis of child and adolescent psychiatrists. Data were analyzed using SPSS v. 22 by mean, percentage, standard deviation, and Pearson correlation coefficient. Results: The relationship between the mothers' mean EI and parenting stress scores were not significant with the age, grade of education, duration of the treatment, and the comorbidities in children (P>0.05). There was a meaningful relationship between the components of EI (P<0.05) and the total score of EI with parenting stress scores (P= 0.001, r= -0.42). Higher emotional intelligence is associated with a lower parenting stress score. Conclusion: Mothers of ADHD youth who had higher EI had less parenting stress.


Author(s):  
Dwi Nur Rahmawati ◽  
Bunga Astria Paramashanti ◽  
Rosma Fyki Kamala

<p><strong>Background:</strong> Results of Riskesdas in 2013 showed the prevalence of stunting by 37%. Stunting is a growth disorders such as chronic malnutrition will cause linear growth of troubled children. Stunting apart from the impact of the development of IQ, cognitive and motoric sector but also on emotional development. Hyperactivity disorder or ADHD (Attention  Deficit  Hyperactivity Disorder) is one of the emotional problems in children.</p><p><strong>Objective</strong>: The general objective of this study was to determine the relationship between stunting with attention deficit hyperactivity disorder in children aged 36-59 months in the Sedayu Subdistrict, Bantul District, Yogyakarta in 2017.</p><p><strong>Methods:</strong> This study used a cross-sectional approach. The samples studied amount 185 samples retrieval techniques probability proportional to size (PPS). Variable examined included stunting and hyperactivity disorder.\</p><p><strong>Results:</strong> The prevalence of stunting in this study was 34,2%, meanwhile the prevalence of hyperactivity was 28,8%. Chi-square analysis showed no significant association between stunting with attention deficit hyperactivity disorder (OR=0,98; 95%CI: 0,50-1,91).</p><p><strong>Conclusion:</strong> there was no association between stunting and hyperactivity in young children.</p><p> </p><p><strong>KEYWORDS: </strong>stunting, hyperactivity, ADHD, children </p>


2015 ◽  
Vol 29 (1) ◽  
pp. 26-32 ◽  
Author(s):  
Ching-Wen Huang ◽  
Chung-Ju Huang ◽  
Chiao-Ling Hung ◽  
Chia-Hao Shih ◽  
Tsung-Min Hung

Children with attention deficit hyperactivity disorder (ADHD) are characterized by a deviant pattern of brain oscillations during resting state, particularly elevated theta power and increased theta/alpha and theta/beta ratios that are related to cognitive functioning. Physical fitness has been found beneficial to cognitive performance in a wide age population. The purpose of the present study was to investigate the relationship between physical fitness and resting-state electroencephalographic (EEG) oscillations in children with ADHD. EEG was recorded during eyes-open resting for 28 children (23 boys and 5 girls, 8.66 ± 1.10 years) with ADHD, and a battery of physical fitness assessments including flexibility, muscular endurance, power, and agility tests were administered. The results indicated that ADHD children with higher power fitness exhibited a smaller theta/alpha ratio than those with lower power fitness. These findings suggest that power fitness may be associated with improved attentional self-control in children with ADHD.


2019 ◽  
pp. 85-91
Author(s):  
Dinh Duong Le ◽  
Van Thang Vo ◽  
Thi Mai Nguyen ◽  
Thi Han Vo ◽  
Huu Chau Duc Nguyen ◽  
...  

Objectives: The study aims to explore the prevalence of attention deficit hyperactivity disorder and to examine the associated factors with ADHD among primary students by Vanderbilt ADHD rating scale for teacher and parents. Methods: A cross-sectional study design was conducted in 564 students who selected randomly in 4 primary schools in Hue city. Vanderbilt ADHD rating scale for parents and teachers were applied to evaluate the ADHD of children over 6 months ago. Results: The overall prevalence of children who had high risk with ADHD was 4.1% (95%CI: 2.44 - 5.72), including 4.6% and 4.8% in the rating of teachers and parents, respectively. Male was more likely to have ADHD than female (OR adj: 4.64 (95%CI: 1.53 - 14.05) and lack of closely friend (OR adj: 5.11 (95% CI: 2.13 - 12.24). Conclusion: Vanderbilt ADHD diagnosis rating scale for teachers and parents can be used to early recognization children with a high risk of ADHD. Key words: ADHD, Vanderbilt, ratings scale, teacher, parent, children


2020 ◽  
Vol 10 (01) ◽  
pp. e97-e103
Author(s):  
Irene Rethemiotaki

AbstractAttention-deficit hyperactivity disorder (ADHD) is an increasingly recognized chronic neurodevelopmental disorder. This work aims at studying the prevalence and clinical characteristics of children with ADHD in the United States in the period between 2009 and 2018. Data from the National Health Interview Survey were analyzed by univariate and multivariate statistics to assess the role of socioeconomic factors in the development of ADHD. It has been studied 615,608 children, 51.2% male and 48.7% female. The prevalence of ADHD was 9.13%, with males predominating over females. The number of children with ADHD increased from 2009 to 2018 by 14.8%. As specified by multiple logistic regression analysis, males (odds ratio [OR] 2.38) who have neither mother nor father (OR 1.76) are twice as likely to have ADHD compared with their peers. In addition, family income (OR 1.40) and parent's education (OR 1.12) were significantly associated with ADHD. It has been highlighted the significance of deprivation of both family and financial comfort as primary indicators for ADHD in children. Moreover, children with ADHD were more likely to be males in the age group of 12 to 17.


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