scholarly journals An Anecdotal Case Report of Chronic Lymphatic Leukemia with del(11q) Treated with Ibrutinib: Artificial Nourishment and Physical Activity Program

2020 ◽  
Vol 17 (6) ◽  
pp. 1929 ◽  
Author(s):  
Antonello Sica ◽  
Caterina Sagnelli ◽  
Alfonso Papa ◽  
Massimo Ciccozzi ◽  
Evangelista Sagnelli ◽  
...  
Keyword(s):  
Physical Activity ◽  
Clinical Condition ◽  
Abdominal Cavity ◽  
Exercise Program ◽  
Moderate Physical Activity ◽  
Great Decrease ◽  
Chronic Lymphatic Leukemia ◽  
Adequate Nutrition ◽  
Lymphatic Leukemia ◽  
Artificial Nourishment

Chronic lymphatic leukemia (CLL) is the most frequent type of leukemia in western countries and when association with del(11q) is correlated with a worse prognosis. We reported the clinical case of an 80-year-old patient with CLL related to del(11q) and a BMI of 16.4 kg/m2, who presented a voluminous mass in abdominal cavity (23 × 14 × 4 cm) which occupied the whole of the mesentery and the retroperitoneal space, treated with ibrutinib, adequate nutrition, and a program of physical activity. He showed a great improvement under ibrutinib therapy and took to artificial nourishment and adequate muscle rehabilitation until he recovered his autonomy. In August 2018, a 5-days-a-week training program was started: Physical activity for at least 20 min consisting of a fast walk in the open air three times a week and a moderate physical activity in the remaining two days of at least 20 consecutive minutes (cycling at a regular pace, carrying light weights). The exercise program included also aerobic, upper and lower limb resistance training, chore stability and stretches. The physical condition further improved and remained excellent throughout the follow-up period. In December 2018, his clinical condition was quite normal; a CT showed a great decrease of all lymphoadenomegaly, and FISH test did not show del(11q). He continued to cultivate his land, while still being treated with ibrutinib. The combination of the right therapy, adequate nutrition, and muscle rehabilitation is the best solution to improve the clinical condition of old cachectic CLL del(11q) patient.

scholarly journals Neurochemical and Cognitive Beneficial Effects of Moderate Physical Activity and Catechin in Aged Rats

Antioxidants ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 621
Author(s):  
Margarita R. Ramis ◽  
Fiorella Sarubbo ◽  
David Moranta ◽  
Silvia Tejada ◽  
Jerònia Lladó ◽  
...  
Keyword(s):  
Physical Activity ◽  
Healthy Aging ◽  
Motor Coordination ◽  
Neuroprotective Effect ◽  
Life Quality ◽  
Exercise Program ◽  
Moderate Physical Activity ◽  
Brain Health ◽  
Protein Levels ◽  
Age Related

A healthy aging process is a requirement for good life quality. A relationship between physical activity, the consumption of antioxidants and brain health has been stablished via the activation of pathways that reduce the harmful effects of oxidative stress, by inducing enzymes such as SIRT1, which is a protector of brain function. We analyzed the cognitive and neurochemical effects of applying physical exercise in elderly rats, alone or in combination with the antioxidant catechin. Several tests of spatial and episodic memory and motor coordination were evaluated. In addition, brain monoaminergic neurotransmitters and SIRT1 protein levels were assessed in the brains of the same rats. The results show that physical activity by itself improved age-related memory and learning deficits, correlating with the restoration of brain monoaminergic neurotransmitters and SIRT1 protein levels in the hippocampus. The administration of the antioxidant catechin along with the exercise program enhanced further the monoaminergic pathways, but not the other parameters studied. These results agree with previous reports revealing a neuroprotective effect of physical activity, probably based on its ability to improve the redox status of the brain, demonstrating that exercise at an advanced age, combined with the consumption of antioxidants, could produce favorable effects in terms of brain health.

scholarly journals Physical Exercise and Grip Strength in Patients Intervened through Bariatric Surgery

Aquichan ◽  
2019 ◽  
Vol 19 (3) ◽  
pp. 1-10
Author(s):  
Jéssica Pamela Noack Segovia ◽  
Antonio Sánchez López ◽  
Inmaculada García-García ◽  
Raquel Rodríguez-Blanque ◽  
Ximena Alejandra León Ríos ◽  
...  
Keyword(s):  
Physical Activity ◽  
Bariatric Surgery ◽  
Clinical Trial ◽  
Physical Exercise ◽  
Grip Strength ◽  
Intervention Group ◽  
Exercise Program ◽  
Moderate Intensity ◽  
Control Group ◽  
Moderate Physical Activity

Objective: This work sought to evaluate a physical exercise program of moderate intensity in patients operated of bariatric surgery and its influence on muscle strength. Method: Randomized clinical trial, with an intervention group and a control group. Forty-three patients were operated of bariatric surgery. The intervention group was applied a program of moderate physical activity during six months. Grip strength and bioimpedance were measured at their baseline form, at one month, and six months after surgery. A bivariate study was conducted to observe variable changes. Results: Upon conducting Student´s t for independent samples in all the variables (weight, body mass index, grip strength, lean mass, fat mass, and metabolism), the result is that no significant differences exist between the intervention group and the control group with p > 0.05. Conclusion: A program of moderate physical activity lasting six months in patients intervened of bariatric surgery has no significant result in the development of muscle mass evaluated through manual dynamometry and bioimpedance.

HUBUNGAN AKTIVITAS FISIK DENGAN FUNGSI KOGNITIF LANSIA DI PANTI WREDHA YAYASAN SOSIAL SALIB PUTIH SALATIGA

2019 ◽  
pp. 137-143
Author(s):  
Dennys Christovel Dese ◽  
Cahyo Wibowo
Keyword(s):  
Physical Activity ◽  
Cognitive Function ◽  
The Elderly ◽  
Moderate Physical Activity ◽  
Cross Sectional ◽  
Significance Level ◽  
The Social ◽  
Normal Cognitive Function ◽  
Intellectual Capacity ◽  
Independent Variable

Peningkatan jumlah lansia setiap tahunnya harus dijadikan perhatian, akibat adanya peningkatan jumlah lansia masalah yang dihadapi akan menjadi semakin kompleks, salah satunya adalah masalah yang berkaitan dengan gejala penuaan. Menurunnya kapasitas intelektual berhubungan erat dengan fungsi kognitif pada lansia. Aktivitas fisik diidentifikasi sebagai salah satu faktor yang mempengaruhi fungsi kognitif. Aktivitas fisik bermanfaat untuk lansia sebagai pencegahan dan demensia. Penelitian ini merupakan penelitian analitik observasional dengan menggunakan pendekatan cross sectional. Penelitian dilakukan di yayasan sosial Panti Wredha Salib Putih Salatiga pada bulan Juni 2018. Populasi dalam penelitian ini adalah lansia yang berumur ?60 tahun. Subjek pada penelitian ini berjumlah 16 responden. Variabel independen dalam penelitian ini adalah aktivitas fisik yang dinilai dengan menggunakan instrument GPAQ. Sedangkan variabel dependen dalam penelitian ini adalah fungsi kognitif yang dinilai dengan instrument MMSE. Terdapat 4 orang (25%) yang masuk dalam kategori fungsi kognitif normal dengan kategori aktifitas fisik sedang 1 orang dan aktifitas berat 3 orang, kemudian yang termasuk dalam kategori gangguan fungsi kognitif ringan sebanyak 11 orang (68,75%), dengan kategori aktifitas fisik sedang 8 orang dan aktifitas ringan 3 orang. Sedangkan yang termasuk dalam kategori gangguan fungsi kognitif berat, terdapat 1 orang (6,25%) dengan kategori aktifitasnya ringan. Taraf signifikansi antar variabel tingkat aktifitas fisik dan fungsi kognitif pada lansia adalah p=0.007 atau p<0,05, sehingga dapat disimpulkan ada  hubungan antara tingkat aktifitas fisik dengan fungsi kognitif pada lansia.   Increasing the number of elderly people every year should be a concern, due to an increase in the number of elderly problems faced will become increasingly complex, one of which is a problem related to the symptoms of aging. Decreased intellectual capacity is closely related to cognitive function in the elderly. Physical activity is identified as one of the factors that influence cognitive function. Physical activity is beneficial for the elderly as prevention and dementia. This study was an observational analytic study using a cross sectional approach. The study was conducted at the social foundation nursing home in the white cross in June 2018. The population in this study was elderly aged ≥60 years. The subjects in this study were 16 respondents. The independent variable in this study is physical activity that is assessed using the GPAQ instrument. While the dependent variable in this study was cognitive function which was assessed by the MMSE instrument. There are 4 people (25%) who fall into the category of normal cognitive function with moderate physical activity categories 1 person and heavy activities 3 people, then those included in the category of mild cognitive function disorders are 11 people (68.75%), with the category of physical activity being 8 people and 3 light activities. While those included in the category of severe cognitive function disorders, there is 1 person (6.25%) with a mild activity category. The significance level between the level of physical activity and cognitive function in the elderly is p = 0.007 or p <0.05, so it can be concluded that there is a relationship between the level of physical activity and cognitive function in the elderly.

Lifestyle, Maternal Nutrition and Healthy Pregnancy

2020 ◽  
Vol 19 (2) ◽  
pp. 132-140
Author(s):  
Alfonso Mate ◽  
Claudia Reyes-Goya ◽  
Álvaro Santana-Garrido ◽  
Carmen M. Vázquez
Keyword(s):  
Physical Activity ◽  
Maternal Nutrition ◽  
Muscle Tone ◽  
Maternal Diet ◽  
Perinatal Outcomes ◽  
Psychosocial Health ◽  
World Health ◽  
Large For Gestational Age ◽  
Moderate Physical Activity ◽  
Healthy Pregnancy

: Healthy lifestyle habits spanning from preconception to postpartum are considered as a major safeguard for achieving successful pregnancies and for the prevention of gestational diseases. Among preconception priorities established by the World Health Organization (WHO) are healthy diet and nutrition, weight management, physical activity, planned pregnancy and physical, mental and psychosocial health. Most studies covering the topic of healthy pregnancies focus on maternal diet because obesity increases the risks for adverse perinatal outcomes, including gestational diabetes mellitus, large for gestational age newborns, or preeclampsia. Thus, foods rich in vegetables, essential and polyunsaturated fats and fibre-rich carbohydrates should be promoted especially in overweight, obese or diabetic women. An adequate intake of micronutrients (e.g. iron, calcium, folate, vitamin D and carotenoids) is also crucial to support pregnancy and breastfeeding. Moderate physical activity throughout pregnancy improves muscle tone and function, besides decreasing the risk of preeclampsia, gestational diabesity (i.e. diabetes associated with obesity) and postpartum overweight. Intervention studies claim that an average of 30 min of exercise/day contributes to long-term benefits for maternal overall health and wellbeing. Other factors such as microbiome modulation, behavioural strategies (e.g. smoking cessation, anxiety/stress reduction and sleep quality), maternal genetics and age, social class and education might also influence the maternal quality of life. These factors contribute to ensure a healthy pregnancy, or at least to reduce the risk of adverse maternal and foetal outcomes during pregnancy and later in life.

Acute Lymphoblastic Crisis in a Patient with Chronic Lymphatic Leukemia

1975 ◽  
Vol 54 (5) ◽  
pp. 306-311 ◽  
Author(s):  
A. Klajman ◽  
A. Yaretzky ◽  
J. Manor ◽  
Z. Steiner
Keyword(s):  
Chronic Lymphatic Leukemia ◽  
Lymphatic Leukemia

scholarly journals Exercise referral to promote cardiovascular health in stroke and TIA patients: a pilot feasibility study

2020 ◽  
Vol 6 (1) ◽  
pp. e000929
Author(s):  
Sheharyar Baig ◽  
Bethany Moyle ◽  
Jessica Redgrave ◽  
Arshad Majid ◽  
Ali Ali
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Perceived Exertion ◽  
Cardiovascular Health ◽  
Rating Of Perceived Exertion ◽  
Moderate Physical Activity ◽  
Post Intervention ◽  
Related Quality ◽  
Exercise Programmes

ObjectivesExercise programmes studied after stroke often involve specialist supervision. Determine the feasibility and safety for people with stroke (PwS) or transient ischaemic attack (TIA) participating in readily accessible, non-stroke specialised, community-based exercise programmes.MethodsParticipants were recruited into a structured, group-based, 12-week programme of aerobic and resistance exercise delivered two times per week at one of five local leisure centres. Completion rates, successful attainment of intended exercise intensity (Borg Rating of Perceived Exertion (RPE)) and safety outcomes were recorded. Measures of physical activity (International Physical Activity Questionnaire), health-related quality of life (EQ-5D) and blood pressure (BP) were recorded at baseline and day 1 post intervention.Results79% of participants completed >75% of the intended sessions, with >90% attainment of intended RPE. Exercise was safe with no serious and very few minor adverse events related to exercise. Exercise led to significant increases in EQ-5D (Best of Health p<0.001), levels of weekly moderate physical activity (p<0.001) and decreases in systolic BP (mean change [95% CI]=−5.4 mmHg [−2.84 to −7.96]; p<0.001).ConclusionGeneralised exercise programmes delivered through existing local services, appears feasible, safe and may improve quality of life, physical activity and systolic BP, for PwS and TIA.

scholarly journals Moderate Physical Activity Correlates with Elevated Leptin in Physically Active 10–12-Year-Old Boys with Normal BMI

2013 ◽  
Vol 117 (2) ◽  
pp. 358-366 ◽  
Author(s):  
Antonio Cicchella ◽  
Claudio Stefanelli ◽  
Toivo Jürimäe ◽  
Meeli Saar ◽  
Priit Purge
Keyword(s):  
Physical Activity ◽  
Moderate Physical Activity ◽  
Physically Active
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