scholarly journals Spatial Patterns of Endometriosis Incidence. A Study in Friuli Venezia Giulia (Italy) in the Period 2004–2017

2021 ◽  
Vol 18 (13) ◽  
pp. 7175
Author(s):  
Dolores Catelan ◽  
Manuela Giangreco ◽  
Annibale Biggeri ◽  
Fabio Barbone ◽  
Lorenzo Monasta ◽  
...  
Keyword(s):  
Spatial Gradient ◽  
Age Group ◽  
Bayesian Approaches ◽  
Incidence Data ◽  
Hospital Discharge Records ◽  
Life Course Studies ◽  
Fully Bayesian ◽  
Age Range ◽  
Incident Cases ◽  
Friuli Venezia Giulia

Background: Diagnosis of endometriosis and evaluation of incidence data are complex tasks because the disease is identified laparoscopically and confirmed histologically. Incidence estimates reported in literature are widely inconsistent, presumably reflecting geographical variability of risk and the difficulty of obtaining reliable data. Methods: We retrieved incident cases of endometriosis in women aged 15–50 years using hospital discharge records and pathology databases of the Friuli Venezia Giulia region in the calendar period 2004–2017. We studied the spatial pattern of endometriosis incidence applying Bayesian approaches to Disease Mapping, and profiled municipalities at higher risk controlling for multiple comparisons using both q-values and a fully Bayesian approach. Results: 4125 new cases of endometriosis were identified in the age range 15 to 50 years in the period 2004–2017. The incidence rate (x100 000) is 111 (95% CI 110–112), with a maximum of 160 in the age group 31–35 years. The geographical distribution of endometriosis incidence showed a very strong north-south spatial gradient. We consistently identified a group of five neighboring municipalities at higher risk (RR 1.31 95% CI 1.13; 1.52), even accounting for ascertainment bias. Conclusions: The cluster of 5 municipalities in the industrialized and polluted south-east part of the region is suggestive. However, due to the ecologic nature of the present study, information on the patients’ characteristics and exposure histories are limited. Individual studies, including biomonitoring, and life-course studies are necessary to better evaluate our findings.

scholarly journals Effect of Population-Wide Hepatitis B Vaccination in Preventing Liver Cancer Among Children and Young Adults in the United States

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 11s-11s
Author(s):  
A.Z. Shams ◽  
V. Winkler ◽  
H. Pohlabeln ◽  
V. Arndt ◽  
U. Haug
Keyword(s):  
Liver Cancer ◽  
Cancer Incidence ◽  
Cancer Registries ◽  
The United States ◽  
Incidence Rates ◽  
Age Group ◽  
Incidence Data ◽  
Hbv Vaccination ◽  
The Us ◽  
Incident Cases

Background: Liver cancer is the second most common cause of death from cancer worldwide1. In 2013, 79,2000 new cases of liver cancer and 818,000 deaths occurred globally2,3. Chronic infection with HBV accounts for at least 50% of liver cancer globally4. In the United States (US), liver cancer constitute the ninth leading cause of cancer death. The incidence of the cancer has persistently increased in the recent decades. Universal HBV vaccination was introduced in 1992 in the US. However, incidence trends of liver cancer among US children is poorly researched or relevant studies are not up-to-date5. Aim: This study aims to explore the effect of HBV population-wide vaccination program in reducing liver cancer incidence in the vaccinated children and adolescents in the US. Methods: Liver cancer incidence data were obtained from Cancer Incidence in Five Continents (CI5) databases (volumes I to X) from International Agency for Cancer Research (IARC). Data acquisition and analysis covered available incidence data between 1978-2007 from 9 cancer registries from Surveillance, Epidemiology, and End Results Program (SEER) from the US presented in the CI5 databases. Age-specific incidence rates of liver cancer (based on 5 year age groups ie 5-9 year, 10-14 year and 15-19 years) were calculated using age and sex-disaggregated incidence and population data from the SEER cancer registries. Stata software version 14.0 (StataCorp, USA) was used to calculate age-specific incidence rates, using number of liver cancer incident cases in each age group by the number of population in the respective age group. Age-specific rates were analyzed by period of diagnosis and by birth year. Rate ratios were estimated from age-group-specific Poisson regressions. Results: A total of 140 liver cancer incident cases were registered in the 9 SEER registries between 1978 to 2007 in the US. The incidence rate of liver cancer in children 5 to 9 years of age from 1978-1982 was 0.10 per 100,000 children. The incidence increased to 0.16 for the period from 2003-2007. The same trend is seen for the age group 10-14 and 15-19 years of age. Overall, age-specific incidence rates for liver cancer increased across age groups of 5-9, 10-14 and 15-19 year in the population covered by the 9 SEER registries in the US. However, risk estimates (incidence rate ratios, resulted from age-group-specific Poisson regressions did not show statistical significant effects. Conclusion: While the global response to implement population-wide HBV vaccination program is out of question, efforts to establish processes to evaluate the effect of such programs seems to be incomparably limited. Estimating the effect of HBV vaccination will relatively improve with time as further incidence data become available eg upon publication of data from new volume of CI5 databases.

scholarly journals Estimating, monitoring, and forecasting COVID-19 epidemics: a spatiotemporal approach applied to NYC data

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Vinicius V. L. Albani ◽  
Roberto M. Velho ◽  
Jorge P. Zubelli
Keyword(s):  
New York ◽  
New York City ◽  
Census Data ◽  
Age Group ◽  
Age Classes ◽  
Basic Model ◽  
Monitoring And Forecasting ◽  
Group Sex ◽  
Age Range ◽  
Spatial Locations

AbstractWe propose a susceptible-exposed-infective-recovered-type (SEIR-type) meta-population model to simulate and monitor the (COVID-19) epidemic evolution. The basic model consists of seven categories, namely, susceptible (S), exposed (E), three infective classes, recovered (R), and deceased (D). We define these categories for n age and sex groups in m different spatial locations. Therefore, the resulting model contains all epidemiological classes for each age group, sex, and location. The mixing between them is accomplished by means of time-dependent infection rate matrices. The model is calibrated with the curve of daily new infections in New York City and its boroughs, including census data, and the proportions of infections, hospitalizations, and deaths for each age range. We finally obtain a model that matches the reported curves and predicts accurate infection information for different locations and age classes.

A Descriptive study to assess the level of knowledge regarding Menopause among rural women of age group 45-55 years at Kot Bhalwal, Jammu

2021 ◽  
pp. 315-316
Author(s):  
Deva Pon Pushpam. I.
Keyword(s):  
Rural Women ◽  
Sampling Technique ◽  
Descriptive Study ◽  
Demographic Variables ◽  
Average Level ◽  
Western World ◽  
Age Group ◽  
Validity And Reliability ◽  
Level Of Knowledge ◽  
Age Range

One of the most important stage in women`s life is menopause. The word menopause simply refers to the last menstrual period which is defined by not having had a period in 12 months. The average age of menopause in western world is 51 years while as in India it is 47.5 years and the normal age range for the occurrence of menopause is somewhat between the age of 45 and 55 years. A descriptive study was conducted to assess the level of knowledge regarding menopause among rural women of age group 45-55 years at Kot Bhalwal, Jammu. The objectives were to assess the level of knowledge regarding menopause among rural women of age group 45-55 years at Kot Bhalwal, Jammu and to associate the level of knowledge regarding menopause with their selected socio demographic variables. Quantitative approach, descriptive research design was used. 100 women of 45–55 years age who fulfil the inclusion and exclusion criteria were selected using purposive sampling technique. A self-structured questionnaire was developed for the study. The tool was tested for content validity and reliability prior to the study. The collected data was tabulated, analysed and interpreted by using descriptive and inferential statistics and findings showed that majority of the sample 97(97%) had below average level of knowledge, 3(3%) had average level of knowledge and 0(0%) had above average level of knowledge and there was no significant association between the selected socio-demographic variables and the level of knowledge.

ELECTROCARDIOGRAPHIC PATTERNS OF NORMAL CHILDREN FROM BIRTH TO FIVE YEARS OF AGE

PEDIATRICS ◽  
1951 ◽  
Vol 8 (3) ◽  
pp. 349-361
Author(s):  
GERARD GROS ◽  
ARMOND GORDON ◽  
ROBERT MILLER
Keyword(s):  
Left Ventricle ◽  
Transition Zone ◽  
Age Groups ◽  
Later Life ◽  
Distinct Pattern ◽  
Age Group ◽  
S Wave ◽  
Normal Children ◽  
Age Range ◽  
Q Wave

The ECGs of 104 normal children from a few hours old to 5 years of age were studied. These ECGs consisted of the standard limb leads, the aV limb leads and six precordial leads: V4R, V1, V2, V4, V5 and V6. While the number of cases in each group are small, the following conclusions are suggested by this study: 1. ECGs of the newborn infant present important variations from those seen in later life. This is especially true during the first week of life. Thereafter the contour evolves [SEE FIG. 2 IN SOURCE PDF] in a definite manner until the adult-like pattern is reached. 2. The vertical and semivertical "electric" positions were the most frequently encountered in this age group. 3. P-waves present a rather permanent pattern in this age range: a. is usually upright in lead 1 and 2, aVF, V4, V5 and V6. b. is usually inverted in lead 2 and aVR. c. is either upright, inverted or diphasic in lead 3, aVL, V4R, V1 and V2. 4. The P-R interval varies from 0.10 sec. minimum to 0.16 sec. maximum with the average being 0.12 sec. in this age range. It tends to become greater in the older age groups. 5. QRS duration is shorter in the younger age groups and increases slowly with age. 6. Polyphasic, M-shaped or slurred QRS complexes are not uncommon in the ECGs of normal children in this age range. 7. A Q wave is frequently absent in lead 1 and in all chest leads during the first week of life. Thereafter up to 5 years of age the pattern of the Q wave is as follows: a. Q is generally absent in lead 1, V4R, V1, V2 and V4. b. Q is generally present in lead 3, V4R, aVF, V5 and V6. 8. There is a distinct pattern of right ventricular dominance in leads from the sternum and to its right at birth. This pattern gradually undergoes involution, probably related to normal physiologic development, until the left ventricle becomes dominant. Thus the evolution of the S-wave parallels a gradual involution of the R-wave in right precordial leads and probably also in aVR. This dominance of the left ventricle over the entire precordium is usual by about 3 years, but may be delayed normally until 5 years of age. 9. The T-wave is upright or diphasic in V4R, V1, and V2 and inverted in V5 and V6 for the first 24 hours of life; it gradually alters so that by the fourth day it is inverted in V4R, V1 and V2 and upright in V5 and V6 and thereafter. 10. The transition zone of QRS varies from one age group to another and tends in some ages to be broad. In some instances no real transition zone can be determined.

scholarly journals THE CASE OF DEATH FROM LIVER CIRRHOSIS IN THE FEMALE PATIENT WITH HIV INFECTION AND INFILTRATIVE PULMONARY TUBERCULOSIS

2013 ◽  
Vol 18 (1) ◽  
pp. 49-54
Author(s):  
I. Yu. Babaeva ◽  
M. G. Avdeeva ◽  
N. P. Shevchenko ◽  
V. V Kulagin ◽  
G. V Chumachenko ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Hepatitis C ◽  
Pulmonary Tuberculosis ◽  
Hiv Infection ◽  
Chronic Viral Hepatitis ◽  
Age Group ◽  
Viral Hepatitis C ◽  
Comparative Results ◽  
Age Range ◽  
Chronic Viral Hepatitis C

The paper presents comparative results of estimation of mortality from HIV infection, tuberculosis (TB), fibrosis and cirrhosis of the liver of nonalcoholic nature according to age group for the residents of the Krasnodar region for the period 2006 to 2011. The average age range of the probable development of death from HIV infection was 35-39, from tuberculosis - 45-49 and from liver cirrhosis 55-59 years. Given clinical case is demonstrating the importance of the underestimation of hepatitis "C" complicating diagnosis of cirrhosis in patients with HIV infection, suffering from secondary diseases: pulmonary tuberculosis, cytomegalovirus, toxoplasmosis, herpes infection, candidiasis. After a comprehensive review of the examples the authors provide recommendations for monitoring and management of patients with ТВ and HIV infection and chronic viral hepatitis "C".

scholarly journals Clinical Presentation of Heart Failure Patients Admitted in National Institute of Cardiovascular Diseases, Dhaka

2014 ◽  
Vol 15 (1) ◽  
pp. 18-22
Author(s):  
Md. Toufiqur Rahman ◽  
A A S Majumder ◽  
Afzalur Rahman ◽  
Abdul Wadud Chowdhury
Keyword(s):  
Heart Failure ◽  
Cardiovascular Diseases ◽  
Ischemic Cardiomyopathy ◽  
Clinical Presentation ◽  
The United States ◽  
Age Group ◽  
Socioeconomic Condition ◽  
Heart Failure Patients ◽  
Coronary Syndrome ◽  
Incident Cases

Background: Heart failure is a complex clinical syndrome that arises secondary to abnormalities of cardiac structure and/or function (inherited or acquired) that impair the ability of the left ventricle to fill or eject blood. The worldwide prevalence and incidence rates of heart failure (HF) are approaching epidemic proportions, as evidenced by the relentless increase in the number of HF hospitalizations, the growing number of HF-attributable deaths, and the spiraling costs associated with the care of HF patients. Worldwide, HF affects nearly 23 million people. In the United States, HF affects approximately 4.7 million persons (1.5 to 2 percent of the total population), with approximately 550,000 incident cases of HF diagnosed annually. Heart failure patients have various presentations and different etiologies. So, this study aimed to see the different clinical presentations of hospitalized heart failure patients. Methods: This study was done to see Clinical Presentation of Heart Failure Patients admitted in National Institute of Cardiovascular Diseases, Dhaka. Total 2112 patients were enrolled for this study during the period of August 2006 to July 2011. Results: Most of the patients (65%) were of 51-70 years age group. 75% (1584) patients were male. 98% patients presented with SOB, 95% patients had basal crepitation, 74% had orthopnoea, 59% had Paroxysmal Nocturnal Dyspoea (PND), 40% had leg edema and 25% had raised JVP. Average heart rate was 85 beats/min, average systolic B.P. was 118 mm Hg and average diastolic B.P. was 73 mm Hg. 45% population had hypertension, 29% patients had diabetes and 27% had concomitant respiratory illness. Average EF was 38%. Ischemic Cardiomyopathy was the commonest (39%) cause of heart failure, acute coronary syndrome was the second leading (29%) cause and valvular heart disease is the third common cause.Conclusion: Most of the heart failure patients are elderly age group. Most of the patients presented with shortness of breath and bilateral basal creps. Most patients had co-morbid other illness that influences the natural course of heart failure patients. Most common causes are ischemic cardiomyopathy, a sequel of ischemic insult of the heart. So, patients of acute or chronic ischemic heart diseases should be treated and follow up with care, considering their socioeconomic condition also. DOI: http://dx.doi.org/10.3329/jom.v15i1.19854 J Medicine 2014; 15: 18-22

scholarly journals Prevalence of carotid and femoral artery atherosclerosis among the Ivanovo Oblast population: data from the ATEROGEN-Ivanovo study

2021 ◽  
Vol 20 (5) ◽  
pp. 2994
Author(s):  
A. I. Ershova ◽  
T. V. Balakhonova ◽  
A. N. Meshkov ◽  
V. A. Kutsenko ◽  
E. B. Yarovaya ◽  
...  
Keyword(s):  
Femoral Artery ◽  
Carotid Atherosclerosis ◽  
Subclinical Atherosclerosis ◽  
Population Data ◽  
Age Group ◽  
Russian Regions ◽  
High Prevalence ◽  
Age Range ◽  
Very High ◽  
Low Cardiovascular Risk

Aim. To study the prevalence of carotid (CA) and femoral artery (FA) atherosclerosis among Russian population, mainly in middle age group, using a representative sample of one of the Central Russian regions.Material and methods. The analysis included participants of the ATEROGEN-Ivanovo study (sub-study of the ESSE-RF conducted in the Ivanovo region) aged 40-67 years, who were invited for CA and FA ultrasound to assess plaque presence. A total 1102 people were examined, which was >80% of the original sample.Results. The age of subjects was 54 [48; 60] years (men, 28%). Only 11,2% of participants took statins; 30,9% had low cardiovascular risk (CVR), 35,6% — moderate CVR, 21,8% — high CVR, and 11,8% — very high CVR. The incidence of at least one plaque in CA or FA was 73,6%. The prevalence of CA atherosclerosis was 76,4% in men and 59,1% in women, FA atherosclerosis — 54,9% and 28,3%, respectively. Furthermore, plaques were detected already at the age of 40. The incidence of plaques significantly increased with age, with the exception of carotid atherosclerosis in men, a significant increase in the incidence of which stopped at 45 years of age.Conclusion. Among the Ivanovo population aged 40-67 with a predominance of low-to-moderate CVR patients, there is a high prevalence of carotid and femoral atherosclerosis, which indicates a high potential for using ultrasound for diagnosing subclinical atherosclerosis in assessing CVR in people of this age range.

Suicide and Parasuicide in Childhood and Early Adolescence

1985 ◽  
Vol 146 (5) ◽  
pp. 459-463 ◽  
Author(s):  
Donald J. Brooksbank
Keyword(s):  
Early Adolescence ◽  
Attempted Suicide ◽  
Psychiatric Services ◽  
Age Group ◽  
Deliberate Self Harm ◽  
England And Wales ◽  
The Social ◽  
Self Harm ◽  
Age Range

Suicide is intentional self-killing, and parasuicide an act of deliberate self-harm—either by injury, ingestion or inhalation—not resulting in death (Blacket al,1982). Both are rare under the age of 12 and the rate of suicide in those under 16 remains consistently low. Referrals to psychiatric services reported by Shaffer (1974) indicated that 7–10% were for threatened or attempted suicide, while Hawton (1982) quoted studies giving the incidence as 10–33% for children aged six to 12; in England and Wales (1962–1968), suicide accounted for 0.6% of deaths in the 10–14 age-range. McClure (1984) found that between 1975 and 1980, only ten such deaths were recorded in the 13-and-under range, and 26 deaths in the 14 year-olds, after which the number of suicides rose sharply with each successive year. That study also showed that parasuicide was most common in the 15–24 age-group, but at younger ages there was a higher proportion of undetermined deaths, as against officially recorded suicides. The social taboos associated with suicide may lead to its systematic under-reporting, but even allowing for that, the phenomenon is still a rare one under the age of 16.

scholarly journals Benign melanocytic lesions with emphasis on melanocytic nevi – A histomorphological analysis

2018 ◽  
Vol 8 (2) ◽  
pp. 1384-1388
Author(s):  
Arnab Ghosh ◽  
Dilasma Ghartimagar ◽  
Sushma Thapa ◽  
Brijesh Sathian ◽  
Binaya Shrestha ◽  
...  
Keyword(s):  
Wide Spectrum ◽  
Melanocytic Nevus ◽  
Age Group ◽  
Pigmented Lesions ◽  
Melanocytic Lesions ◽  
Microscopic Features ◽  
Intradermal Nevus ◽  
Malignant Lesions ◽  
Age Range ◽  
Histopathological Subtype

Background: Melanocytic lesions are common and include both benign and malignant conditions. Benign melanocytic nevus may show varied microscopic features and should be differentiated from malignant lesions. In the present study, we analyse the histopathological pictures of different types of benign melanocytic nevi.Materials and methods: This study was a hospital based retrospective study and all the cases reported as melanocytic nevus in the period from Jan 2014 to June 2018 in the Department of Pathology, Manipal Teaching Hospital were retrieved and analysed in the study.Results: A total of 104 melanocytic lesions including 74 cases of benign melanocytic nevus were reported in the study period. Females were affected more with a female to male ratio of 1.8:1. The age range was 5 to 78 years with mean age of 28 years. Among the female patients, the commonest age group was 21-30 years while among the males; the most affected age group was 11-20. The commonest histopathological subtype was intradermal nevus comprising 73% cases followed by compound nevus.  On analysis of the different sites involved, face, head and neck were found to comprise 92% cases. Epidermal changes including hyperkeratosis, acanthosis were common in intradermal nevus. In most cases, tumor cells were arranged in nests. Melanin pigment was noted in majority of the cases. Secondary changes noted were chronic inflammation, fibrosis and multinucleated giant cells.Conclusion: Benign melanocytic nevus may present in varied age range and show wide spectrum of histological features. All pigmented lesions should be biopsied for its subtypes.

Sign in / Sign up

Export Citation Format

Share Document