scholarly journals Functional and Antioxidant Properties of Plastic Bottle Caps Incorporated with BHA or BHT

Materials ◽  
2021 ◽  
Vol 14 (16) ◽  
pp. 4545
Author(s):  
Yu-Wen Wang ◽  
Ya-Na Li ◽  
Qin-Bao Lin ◽  
Xiao Wang ◽  
Zeng-Hui Li ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Properties ◽  
Butylated Hydroxytoluene ◽  
Scanning Calorimetry ◽  
Removal Torque ◽  
Ir Spectrometry ◽  
Plastic Bottle ◽  
Highly Sensitive ◽  
Ft Ir ◽  
Noncovalent Bonding

In this study, we prepared new antioxidant active plastic bottle caps by incorporating butylated hydroxyanisole (BHA) or butylated hydroxytoluene (BHT) and 2% (w/w) white masterbatch in high-density polyethylene (HDPE). Fourier-transform infrared (FT-IR) spectrometry revealed that the antioxidants and HDPE were uniformly mixed with noncovalent bonding. In addition, the differential scanning calorimetry (DSC) test revealed that the change in melting point and initial extrapolation temperature of the antioxidant active caps was not significant. Sensory evaluation and removal torque tests validated the suitability of the antioxidant active plastic bottle caps in industrial application. The antioxidant activity increased with a greater concentration of BHA and BHT incorporated in both antioxidant active caps (p < 0.05) and with more impact on the BHA cap compared to BHT cap in terms of antioxidant activity. Migration experiments for 10 days at 40 °C and 2 h at 70 °C showed that active antioxidants in the plastic bottle cap were more easily released into fatty foods and milk products that are highly sensitive to oxidation, and the migration of BHA and BHT did not exceed the maximum amount specified in (EC) No 1333/2008 (<200 mg/kg). As such, the antioxidant active plastic bottle caps inhibited oxidation, thereby ensuring higher food quality.

scholarly journals Synthesis and antioxidant properties of 2-(3-(hydroxyimino)methyl)-1H-indol-1-yl)acetamide derivatives

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Chandravadivelu Gopi ◽  
Magharla Dasaratha Dhanaraju
Keyword(s):  
Antioxidant Activity ◽  
Condensation Reaction ◽  
Antioxidant Properties ◽  
Side Chain ◽  
Antioxidant Power ◽  
H Nmr ◽  
Antioxidant Agents ◽  
Phenyl Rings ◽  
Ferric Reducing Antioxidant Power ◽  
Ft Ir

Abstract Background The main aim of this work was to synthesise a novel N-(substituted phenyl)-2-(3-(hydroxyimino) methyl)-1H-indol-1-yl) acetamide derivatives and evaluate their antioxidant activity. These compounds were prepared by a condensation reaction between 1H-indole carbaldehyde oxime and 2-chloro acetamide derivatives. The newly synthesised compound structures were characterised by FT-IR, 1H-NMR, mass spectroscopy and elemental analysis. Furthermore, the above-mentioned compounds were screened for antioxidant activity by using ferric reducing antioxidant power (FRAP) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) methods. Result The antioxidant activity result reveals that most of the compounds were exhibiting considerable activity in both methods and the values are very closer to the standards. Among the synthesised compounds, compound 3j, 3a and 3k were shown remarkable activity at low concentration. Conclusion Compounds 3j, 3a and 3k were shown highest activity among the prepared analogues due to the attachment of halogens connected at the appropriate place in the phenyl ring. Hence, these substituted phenyl rings considered as a perfect side chain for the indole nucleus for the development of the new antioxidant agents.

scholarly journals Zn(II) Complex of Plant Phenolic Chlorogenic Acid: Antioxidant, Antimicrobial and Structural Studies

Materials ◽  
2020 ◽  
Vol 13 (17) ◽  
pp. 3745
Author(s):  
Monika Kalinowska ◽  
Justyna Sienkiewicz-Gromiuk ◽  
Grzegorz Świderski ◽  
Anna Pietryczuk ◽  
Adam Cudowski ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Chlorogenic Acid ◽  
Density Functional ◽  
Salmonella Enteritidis ◽  
Antioxidant Properties ◽  
Antimicrobial Activities ◽  
Butylated Hydroxytoluene ◽  
Antioxidant Power ◽  
Ferric Reducing Antioxidant Power ◽  
Thermochemical Parameters

The structure of the Zn(II) complex of 5-caffeoylquinic acid (chlorogenic acid, 5-CQA) and the type of interaction between the Zn(II) cation and the ligand were studied by means of various experimental and theoretical methods, i.e., electronic absorption spectroscopy UV/Vis, infrared spectroscopy FT-IR, elemental, thermogravimetric and density functional theory (DFT) calculations at B3LYP/6-31G(d) level. DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), FRAP (ferric reducing antioxidant power), CUPRAC (cupric reducing antioxidant power) and trolox oxidation assays were applied in study of the anti-/pro-oxidant properties of Zn(II) 5-CQA and 5-CQA. The antimicrobial activity of these compounds against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, Staphylococcus aureus, Salmonella enteritidis and Candida albicans was tested. An effect of Zn(II) chelation by chlorogenic acid on the anti-/pro-oxidant and antimicrobial activities of the ligand was discussed. Moreover, the mechanism of the antioxidant properties of Zn(II) 5-CQA and 5-CQA were studied on the basis of the theoretical energy descriptors and thermochemical parameters. Zn(II) chlorogenate showed better antioxidant activity than chlorogenic acid and commonly applied natural (L-ascorbic acid) and synthetic antioxidants (butylated hydroxyanisol (BHA) and butylated hydroxytoluene (BHT)). The pro-oxidant activity of Zn(II) 5-CQA was higher than the ligand and increased with the rise of the compound concentration The type of Zn(II) coordination by the chlorogenate ligand strongly affected the antioxidant activity of the complex.

scholarly journals Comparison of the Antioxidant Activity of Malaysian Ginger (Zingiber officinale Roscoe) Extracts with that of Selected Natural Products and its Effect on the Viability of Myoblast Cells in Culture

2021 ◽  
Vol 50 (5) ◽  
pp. 1445-1456
Author(s):  
Nur Fatin Nabilah Mohd Sahardi ◽  
Faizul Jaafar ◽  
Siti Nor Asyikin Zakaria ◽  
Jen Kit Tan ◽  
Mariam Firdhaus Mad Nordin ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Natural Products ◽  
Moringa Oleifera ◽  
Antioxidant Activities ◽  
Antioxidant Properties ◽  
Centella Asiatica ◽  
Butylated Hydroxytoluene ◽  
Therapeutic Effects ◽  
Antioxidant Power ◽  
Ficus Deltoidea

Ginger has been proven to possess various therapeutic effects, including antibacterial, anticancer, anti-inflammatory, and antioxidant effects. However, data on the comparison of ginger antioxidant activity with that of other natural products are still lacking. This study aimed to analyse and compare the antioxidant properties of two types of Malaysian ginger extracts (GE1 and GE2) with that of selected natural products. The antioxidant activities were measured by 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) and ferric reducing antioxidant power (FRAP) assays, while cell viability was determined by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfonyl)-2H-tetrazolium (MTS) assay. The order of the DPPH scavenging activities was as follows: vitamin C > palm tocotrienol-rich fraction (TRF) > á-tocopherol > N-acetylcysteine (NAC) > Ficus deltoidea > butylated hydroxytoluene (BHT) > Centella asiatica > GE2 > GE1 > Moringa oleifera > Kelulut honey; the order of the mean FRAP value was as follows: NAC > á-tocopherol > BHT > TRF > Ficus deltoidea > Moringa oleifera > GE2 = GE1 > Centella asiatica > Kelulut honey. The viability assays showed that both ginger extracts significantly increased the percentage of viable cells (p < 0.05). In conclusion, neither of the ginger extracts was cytotoxic toward cells and both possessed comparable antioxidant properties, indicating their potential for ameliorating oxidative stress.

scholarly journals Antioxidant Activity of Pastinaca sativa L. ssp. sylvestris [Mill.] Rouy and Camus Essential Oil

Molecules ◽  
2020 ◽  
Vol 25 (4) ◽  
pp. 869 ◽  
Author(s):  
Călin Jianu ◽  
Ionuț Goleț ◽  
Daniela Stoin ◽  
Ileana Cocan ◽  
Alexandra Teodora Lukinich-Gruia
Keyword(s):  
Antioxidant Activity ◽  
Essential Oil ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Thiobarbituric Acid ◽  
Oxidation Products ◽  
Butylated Hydroxytoluene ◽  
Synthetic Chemicals ◽  
Main Components ◽  
Cold Pressed

In the last decade, there has been growing interest in the food industry in replacing synthetic chemicals with natural products with bioactive properties. This study’s aims were to determine the chemical composition and the antioxidant properties of the essential oil of Pastianica sylvestris. The essential oil was isolated with a yield of 0.41% (w/v) by steam distillation from the dried seeds and subsequently analysed by GC-MS. Octyl acetate (78.49%) and octyl hexanoate (6.68%) were the main components. The essential oil exhibited an excellent activity for the inhibition of primary and secondary oxidation products for cold-pressed sunflower oil comparable with butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT), which were evaluated using peroxide and thiobarbituric acid values. The antioxidant activity of the essential oil was additionally validated using DPPH radical scavenging (0.0016 ± 0.0885 mg/mL), and β-carotene-linoleic acid bleaching assays. Also, the amounts of total phenol components (0.0053 ± 0.0023 mg GAE/g) were determined.

A Study on Synthesis and Antioxidant Activity Comparison of Novel Stilbenebenzamide Compounds

2019 ◽  
Vol 15 ◽  
Author(s):  
Aleksandra Kładna ◽  
Paweł Berczyński ◽  
Oya Bozdağ Dündar ◽  
Irena Kruk ◽  
Beyza Torun ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Ascorbic Acid ◽  
Antioxidant Activities ◽  
Wide Spectrum ◽  
Antioxidant Properties ◽  
Butylated Hydroxytoluene ◽  
Hydroxyl Group ◽  
Antioxidant Power ◽  
Total Antioxidant

Background: Stilbene phytalexis (1,2-diphenyloethylen) and benzamide are beneficial for human health. To increase the stilbene ring activity, a new series of its derivatives containing benzamide structure was synthesized and evaluated for their in vitro antioxidant power. Methods: 1H nuclear magnetic resonance, mass spectroscopy, and chromatographic analyses were used to confirm the successful synthesis. The antioxidant properties were determined by the elimination of , HO , DPPH , ABTS+ radicals, total antioxidant status (TAS) and the ferric reducing antioxidant activities (TAC) measurements. Results: Stilbenebenzamide compounds showed a wide spectrum of antioxidant ability, however their total antioxidant power was weaker than those of butylated hydroxytoluene (BHT), ascorbic acid, and resveratrol. The highest antiradical activity towards and HO was shown by the compounds with structures containing amine group (SBEBA, SBA) ( : 37.7 – 38.0% and 40.8 – 43.5%, HO : 29.8%, 28.7% inhibition, respectively) at1.25 mM concentration. The antiradical power of SBEBA (0.29) in DPPH assay was lower than those of resveratrol (1.83), ascorbic acid (3.63) and BHT (4.09). The TAS values of the synthesized compounds ranged from 152.9±5.3 to 240.2±6.7µM trolox equivalent/gram (TE/g) and were much lower than those of BHT (1304±43.0), reservatrol (1360±29.0) and ascorbic acid (2782±39.7) µM TE/g. Similarly, the TAC values ranging from 29.7±0.9 to 41.5±1.6 µM TE were weaker than that of resveratrol (239.2 ±6.7 µM TE/g). Conclusion: The results suggest that the presence of hydroxyl group in stilbene ring should be considered in further design of stilbenebenzamide compounds to enhance their antioxidant activity.

scholarly journals Physicochemical and Antioxidant Properties of Cymbopogon citratus Essential Oil

2015 ◽  
Vol 4 (3) ◽  
pp. 36 ◽  
Author(s):  
Maria Del Carmen Vazquez-Briones ◽  
Luis Ricardo Hernandez ◽  
Jose Angel Guerrero-Beltran
Keyword(s):  
Essential Oil ◽  
Chemical Structure ◽  
Antioxidant Properties ◽  
Gas Chromatography Mass Spectrometry ◽  
Tea Leaves ◽  
Cymbopogon Citratus ◽  
Ir Spectrometry ◽  
Naked Eye ◽  
Nmr Techniques ◽  
Ft Ir

<p>In this study, the essential oil (EO) of lemongrass (<em>Cymbopogon citratus</em>) or “lemon tea” leaves was studied. The EO was obtained by the steaming (0.75 ± 0.05%) and distillation (1.5 ± 0.07%), assisted by microwaves, methods. The EO had a refractive index of 1.483 ± 0.001 (20 °C) and a density of 0.873 ± 0.005 g/mL (27 °C). Color parameters of the oil corroborate the yellow hue observed by the naked eye. The Gas chromatography-Mass spectrometry (GC-MS), Fourier Transform Infrared (FT-IR) Spectrometry, and Nuclear Magnetic Resonance (NMR) techniques permitted to characterize the EO and revealed the chemical structure of the major component: citral (neral and geranial). The phenolic compounds content was 149.2 ± 6.0 mg Gallic acid equivalents (GAE) per 100 mL of oil and the antioxidant activity was 44.06 ± 0.20 mg Trolox (T) per 100 mL of essential oil.</p>

scholarly journals Synthesis, Characterization, and Antioxidant Activity of Some 2-Methoxyphenols derivatives

2020 ◽  
Vol 26 (1) ◽  
pp. 112-122
Author(s):  
Shaikha S. AlNeyadi ◽  
Naheed Amer ◽  
Tony G. Thomas ◽  
Ruba Al Ajeil ◽  
Priya Breitener ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
Sulfonic Acid ◽  
Antioxidant Properties ◽  
Causative Factor ◽  
Oxygen Radical ◽  
Design Synthesis ◽  
H Nmr ◽  
Ft Ir ◽  
C Nmr

AbstractOxidative stress is a causative factor in the pathophysiology of numerous diseases, such as diabetes, atherosclerosis, cancer, and neurodegenerative and cardiovascular diseases. Therapeutic antioxidants are promising candidates for preventing and treating conditions in which oxidative stress is a contributing factor. In this study, we report the design, synthesis and antioxidant activity of six compounds containing the 2-methoxyphenol moiety core structure. The synthesized derivatives were characterized using 1H NMR, 13C NMR, Fourier-transform infrared (FT-IR), and elemental analysis spectroscopy. The antioxidant properties of the compounds were evaluated using the 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH), 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS), and oxygen radical absorbance capacity (ORAC) assay. New phenolic acid-derived compounds with antioxidant activity were identified.

scholarly journals Chemical Composition, Antioxidant Properties and Antimicrobial Activity of the Essential Oil of Murraya Paniculata Leaves from the Mountains of Central Cuba

2012 ◽  
Vol 7 (11) ◽  
pp. 1934578X1200701 ◽  
Author(s):  
Elisa Jorge Rodríguez ◽  
Guillermo Ramis-Ramos ◽  
Yvan Vander Heyden ◽  
Ernesto F. Simó-Alfonso ◽  
María Jesús Lerma-García ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Essential Oil ◽  
Seed Oil ◽  
Antioxidant Properties ◽  
Thiobarbituric Acid ◽  
Butylated Hydroxytoluene ◽  
Gas Chromatography Mass Spectrometry ◽  
Butylated Hydroxyanisole ◽  
Inhibitory Effects ◽  
Murraya Paniculata

The essential oil of Murraya paniculata L leaves from the mountains of the Central Region of Cuba, obtained by hydrodistillation, was analyzed by gas chromatography-mass spectrometry. Eighteen compounds, accounting for 95.1% of the oil were identified. The major component was β-caryophyllene (ca. 30%). The antioxidant activity of essential oil was evaluated against Cucurbita seed oil by peroxide, thiobarbituric acid and p-anisidine methods. The essential oil showed stronger antioxidant activity than that of butylated hydroxyanisole and butylated hydroxytoluene, but lower than that of propyl gallate. Moreover, this antioxidant activity was supported by the complementary antioxidant assay in the linoleic acid system and 2, 2′-diphenyl-1-picrylhydrazyl. The essential oil also showed good to moderate inhibitory effects against Klebsiella pneumoniae and Bacillus subtilis.

Antioxidant Properties of Avicennia marina Leaf Extract in Soybean Oil System

2020 ◽  
Vol 16 (8) ◽  
pp. 1245-1251
Author(s):  
Mohammad Molaee ◽  
Mohammad A. Sahari ◽  
Reza E. Kenari ◽  
Shiva Amirkaveei ◽  
Elahe Arbidar
Keyword(s):  
Antioxidant Activity ◽  
Soybean Oil ◽  
Leaf Extract ◽  
Antioxidant Properties ◽  
Thiobarbituric Acid ◽  
Avicennia Marina ◽  
Butylated Hydroxytoluene ◽  
Natural Antioxidant ◽  
Mangrove Plant ◽  
Significant Difference

Background: Despite the widespread use of antioxidants during the storage of oils, oxidation of fats and fatty foods is still reported to be the main reason for their quality drop. Synthetic antioxidants such as butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) completely escape and easily decompose at high temperatures. There are serious problems in relation to the toxicity of BHA, BHT and tertiary butylhydroquinone (TBHQ), possibly due to their metabolism and accumulation in organs and tissues. So finding a useful natural antioxidant is of great importance, and due to the considerable presence of mangrove plant on the Southern Coasts of Iran, this study aims to investigate the antioxidant properties of Avicennia marina leaves. Objective: Evaluation of the antioxidant activity of the Avicennia marina leaf extract and its comparison with synthetic antioxidant TBHQ. Methods: By adding the ethanolic extracts of Avicennia marina leaves at different concentrations (2, 4 and 6 mg/mL) into soybean oil system at room temperature during 20 days and at different intervals, their peroxide (PV), thiobarbituric acid (TBA), conjugated dienes (CD) and conjugated trienes (CT), as well as fatty acid profile were measured. Antioxidant activity of the samples was compared with that of TBHQ sample. Data analysis was performed using SAS, and a comparison of average data was carried out using least significant difference (LSD) at a level of 0.01. Results: The antioxidant activity of 2 and 4 mg/mL concentrations of Avicennia marina leaf extract in soybean oil was comparable with that of 0.2 mg/mL concentration of synthetic TBHQ. As a result, this natural antioxidant can be used for the preservation of soybean oil. Conclusion: Due to the presence of phenols in the leaves, Avicennia marina leaf extract can be used as a rich source of natural antioxidants.

scholarly journals Synthesis, characterization and antioxidant activity of Schiff base and its metal complexes with Fe(II), Mn(II), Zn(II), and Ru(II) ions: Catalytic activity of ruthenium(II) complex

2018 ◽  
Vol 9 (1) ◽  
pp. 22-29 ◽  
Author(s):  
Nevin Turan ◽  
Kenan Buldurun
Keyword(s):  
Antioxidant Activity ◽  
Metal Complexes ◽  
Antioxidant Activities ◽  
Magnetic Moments ◽  
Antioxidant Properties ◽  
Molar Conductance ◽  
Transfer Hydrogenation ◽  
Spectral Studies ◽  
Ft Ir

The synthesis, spectral, catalytic and antioxidant properties of ethyl-2-(2-hydroxy-3-methoxybenzylideneamino)-6-methyl-4,5,6-tetrahydrobenzo[b]thiophene-3-carboxylate (L) substituted iron(II), manganese(II), zinc(II), and ruthenium(II)-arene chlorides are described for the first time. The ligand and its metal complexes were characterized by elemental analysis, molar conductance, magnetic susceptibility measurements, and spectral (1H NMR, 13C NMR, FT-IR, UV-Vis and Mass) techniques. The FT-IR spectra showed that the ligand can act as bidentate or tridentate. Magnetic moments and electronic spectral studies revealed an octahedral geometry for all the complexes obtained. The thermal behavior of the complexes showed that the water molecules were separated in the first step followed immediately by decomposition of the anions and ligand molecules in the subsequent steps. Ru(II) complex was used as catalysts for the transfer hydrogenation of ketones. At the same time, the effect of various bases such as NaOH, KOH, KOBut and NaOAc as organic base were investigated in the transfer hydrogenation of ketones by 2-propanol as the hydrogen source. The complexes and ligand were tested in vitro for their antioxidant activity. The experimental results showed that Ru(II) complex had more potent antioxidant activities than Zn(II), Fe(II), Mn(II) complexes and parent ligand.

Sign in / Sign up

Export Citation Format

Share Document