Mitochondrial Function, Mobility and Lifespan Are Improved in Drosophila melanogaster by Extracts of 9-cis-β-Carotene from Dunaliella salina
Keyword(s):
Carotenoids are implicated in alleviating ageing and age-related diseases in humans. While data from different carotenoids are mixed in their outcomes, those for 9-cis-β-carotene indicate general positive effects, although basic data on its biological impact are limited. Here, we show that supplementation with 9-cis-β-carotene in ageing Drosophila melanogaster improved mitochondrial function in terms of ATP production and whole-body respiration and extended mean lifespan. It also resulted in improved mobility. These data provide a potential biological rational for the beneficial effects of dietary supplementation with 9-cis-β-carotene. These effects may be based on the maintenance of a sound mitochondrial function.
1977 ◽
Vol 12
(1-2)
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pp. 1-5
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Keyword(s):
2018 ◽
Vol 19
(11)
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pp. 3335
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2020 ◽
Vol 319
(6)
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pp. E995-E1007
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2020 ◽
Vol 18
(5)
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pp. 471-479
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Keyword(s):
2002 ◽
Vol 283
(6)
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pp. C1675-C1686
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