scholarly journals Observations on Refractive Status and Risk Factors for Visual Impairment in Children with Disabilities

Medicina ◽  
2021 ◽  
Vol 57 (5) ◽  
pp. 403
Author(s):  
Larisa Bianca Holhoș ◽  
Mihaela Cristiana Coroi ◽  
Liviu Lazăr
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Visual Impairment ◽  
Children With Disabilities ◽  
Control Group ◽  
Refractive Errors ◽  
Healthy Children ◽  
Vitamin D Levels ◽  
Visual Acuity Testing

Vision integrates all the senses and plays a fundamental role in the acquisition of different skills and the general development of a child. Recently, refractive errors and visual impairment have become serious health problems among children. Background and Objectives: The aim of this study was to identify the prevalence of refractive errors and visual impairment in children with disabilities. Moreover, this study aimed to explore the risk factors for visual impairment in children with respect to vitamin D levels, parental smoking, and the use of spectacles. Materials and Methods: We retrospectively analyzed 161 children aged 5–16 years old, divided into two groups: a group of 80 children with disabilities and a control group consisting of 81 clinically healthy children. All the children underwent refraction measurements, visual acuity testing, and plasmatic vitamin D level dosing, measured in ng/mL. Results: Refractive errors and visual impairment were found to have a higher prevalence in the group of children with disabilities than in the control group. Moreover, the plasma level of vitamin D was lower in the group of children with special health needs. Conclusions: Given the present results, children with disabilities should undergo special eye examinations as soon as possible to ensure the quality of their socio-academic lives.

scholarly journals Comparison Between Celiac Patients and Healthy Control Group Regarding Vitamin-Mineral Levels and Complete Blood Count Parameters

2020 ◽  
Author(s):  
Şükrü Güngör ◽  
Can Acıpayam
Keyword(s):  
Vitamin D ◽  
Celiac Disease ◽  
Blood Count ◽  
Complete Blood Count ◽  
Healthy Control Group ◽  
Control Group ◽  
Healthy Children ◽  
Vitamin D Levels ◽  
Healthy Control ◽  
Mineral Levels

INTRODUCTION: We aimed to compare the mean platelet volume (MPV) and plateletcrit (PCT) and vitamin-mineral levels in pediatric celiac disease patients with the healthy control group and to compare the results with the literature. METHODS: In this study, clinical and laboratory data of 80 pediatric patients diagnosed with celiac disease (CD) between July 2017 and December 2018 and 42 healthy children in the same age group were retrospectively analyzed. RESULTS: There was no significant difference between the groups in terms of age and gender (p=0.383, and p=0.462, respectively). The frequency of anemia, folate, iron and vitamin D deficiencies was higher in celiac patients compared to the control group (p=0.001, p=0.027, p<0.001, and p<0.001, respectively). When the patients were evaluated according to their complete blood count and vitamin-mineral levels; hemoglobin (Hb), mean corpuscular volume (MCV), ferritin and vitamin D levels were found to be significantly lower in the CD group compared to the control group (p<0.001, p=0.026, p<0.00, and p=0.001, respectively). Platelet (PLT), PCT, MPV levels were found to be significantly higher in the CD group compared to the control group (p=0.010, p<0.001, and p<0.001, respectively). We found a weakly negative correlation between the vitamin D levels and the degree of the Marsh classification (r: -0.273, and p=0.023). DISCUSSION AND CONCLUSION: Our study have shown that MPV, PCT values are higher and Hb, folate, iron and vitamin D levels are lower in patients with CD compared to healthy controls. We recommend investigating other nutrient deficiencies besides iron deficiency, especially in treatment-resistant anemias. We think that the correlation between vitamin D levels and the degree of histological damage should be elucidated with larger-scale and more comprehensive studies.

scholarly journals Effects of Forest Therapy on Health Promotion among Middle-Aged Women: Focusing on Physiological Indicators

2020 ◽  
Vol 17 (12) ◽  
pp. 4348 ◽  
Author(s):  
Bum-Jin Park ◽  
Chang-Seob Shin ◽  
Won-Sop Shin ◽  
Chung-Yeub Chung ◽  
Si-Hyung Lee ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Vitamin D ◽  
Middle Age ◽  
Control Group ◽  
Middle Aged ◽  
Therapy Program ◽  
Vitamin D Levels ◽  
The City ◽  
Day Program

Women experience more stress in middle age than in other life stages, and health in middle age is vital, because it influences the quality of life in old age. In this study, the effects of a forest therapy program on physiological changes in 53 middle-aged women (divided into two groups) who lived in the city were examined. One group participated in a three-day program in the forest, followed by three days in the city; the other group participated in a three-day program in the city, followed by three days in the forest. Forest experiments were conducted in a “healing forest,” and urban experiments were conducted near a university campus. Blood tests were performed to evaluate the physiological effects of forest therapy. Differences in serotonin levels and vitamin D levels were verified before and after the forest (experimental group) and urban (control group) programs through paired t-tests. Statistically significant increases in serotonin levels were noted for participants in the forest program; vitamin D levels also increased, but not by statistically significant values. The findings of this study verify that forest therapy programs promote health among middle-aged women, and may prevent disease and improve quality of life.

Vitamin D levels in patients with childhood cancer.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e20000-e20000
Author(s):  
Nurdan Tacyildiz ◽  
Gulsah oktay Tanyildiz ◽  
Deniz Tekin ◽  
Can Ates ◽  
Handan Dincaslan ◽  
...  
Keyword(s):  
Vitamin D ◽  
Inverse Correlation ◽  
Control Group ◽  
Healthy Children ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
Patient Groups ◽  
Cell Growth And Differentiation ◽  
Age Range ◽  
Nonparametric Correlation

e20000 Background: There is increasing interest in the possible association between cancer incidence and vitamin D through its role as a regulator of cell growth and differentiation. Although there are several studies related cancer risk and prognosis of cancer, related vit D levels in adult patients there are only few recent studies in pediatric patients. Methods: Between 2010 and 2011, D Vit levels of 45 patients (25 boys, 20 girls; age range: 6 months-17 years, median: 11 years) have been compared to D Vit levels of 22 healthy children with similar age group. Patient groups were leukemias, lymphomas, bone tumors, retinoblastoma (RB), and other tumors. Kruskal-Wallis and Spearman nonparametric correlations test of SPSS has been used for statistics. Results: Although there was no statistically significant difference for vit D levels between control group (range: 7.2-22.8; median: 14.75 ng/ml) and patients (range: 5.5-40.2; median: 16.0 ng/ml),difference between patients groups were significant (Table). Patients with RB have statistically lower level of Vit D than leukemia (p:0.016) and lymphoma groups ( p: 0.047). “Other tumors group” has lower vit D levels than leukemia group (p: 0.024). Since RB and other tumors group have younger age than other patients, Spearsman’s nonparametric correlation has been performed to exclude age effect on the results and no statistically significant correlation between D vit levels and age (p: 0.779) was found, although there was an inverse correlation between age and vit D levels in patient group (p: 0.03). Conclusions: According to our preliminary results, most of the patients and healthy children have low level of Vit D. Especially patients with RB have statistically significant lower level of Vit D than other malignancies which can be subject to future studies for confirmation of our results. In addition, etiologic studies related RB may have a new area. [Table: see text]

Relationship between Serum Vitamin D Levels and Health-Related Quality of Life in Maintenance Hemodialysis Patients

2019 ◽  
Vol 48 (1) ◽  
pp. 67-75 ◽  
Author(s):  
Ali Veysel Kara ◽  
Mehmet Naci Aldemir ◽  
Yasin Emrah Soylu ◽  
Yusuf Kemal Arslan
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Vitamin D ◽  
Kidney Disease ◽  
Serum Vitamin ◽  
Hemodialysis Patients ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Independent Risk Factors

Objectives: Aim of the study was investigating the effect of serum vitamin D levels on health-related quality of life in hemodialysis patients. Method: One-hundred and twenty-three maintenance hemodialysis patients were enrolled in this cross-sectional study. Patients divided into 2 groups according to serum vitamin D levels. A serum 25-hydroxyvitamin D (25[OH] D) level of < 20 ng/mL was identified as vitamin D deficiency (n = 78), and a serum level of ≥20 ng/mL was identified as normal (n = 45). Kidney Disease Quality of Life 36 (KDQOL-36) survey was used for quality of life measurement. Scores of the all of 5 subscales of KDQOL-36 were calculated. Multiple linear regression analyses were used to define independent risk factors affecting the survey. Results: Mean age of patients was 62 and 56% of patients were male. Mean 25(OH) D levels were 11.86 and 29.57 ng/mL, respectively, in 2 groups. There was statistically significant difference between age and Kt/V levels between 2 groups (p = 0.008 and p = 0.041). Age and gender were found as significant predictors of vitamin D deficiency (p = 0.026 and p = 0.021). In symptom and problem list subscale, gender and comorbidity were detected as independent risk factors (p = 0.050 and p = 0.032). Comorbidity was the only independent risk factor for effect of kidney disease subscale (p < 0.001). Independent risk factors associated with burden of kidney disease subscale were comorbidity and serum 25 (OH) D levels (p = 0.003 and p = 0.023). Serum 25(OH) D, gender, and comorbidity were independently associated with physical component summary (PCS) subscale (p < 0.001, p = 0.008, and p = 0.011). The only independently associated factor with mental component summary (MCS) was serum 25(OH) D (p < 0.001). Conclusion: We first showed the relationship between serum vitamin D levels and KDQOL-36 in hemodialysis patients. Lower serum vitamin D levels were negatively associated with burden of kidney disease, PCS, and MCS subscales.

scholarly journals Vitamin D levels in children and adolescents with autism

2020 ◽  
Vol 48 (7) ◽  
pp. 030006052093463
Author(s):  
Esma Şengenç ◽  
Ertuğrul Kıykım ◽  
Sema Saltik
Keyword(s):  
Vitamin D ◽  
Alkaline Phosphatase ◽  
Children And Adolescents ◽  
Autism Spectrum ◽  
Control Group ◽  
Healthy Children ◽  
Birth Season ◽  
Hydroxyvitamin D ◽  
Vitamin D Levels ◽  
Calcium Phosphorus

Objective This study aimed to investigate the relationship between autism spectrum disorder (ASD) and vitamin D levels in children and adolescents. Methods We measured serum 25-hydroxyvitamin D (25-OHD) levels in 1529 patients with ASD aged 3 to 18 years, without any additional chronic diseases. Levels of 25-OHD were compared according to sex, age (<11 or ≥11 years), and birth season. Additionally, laboratory parameters (calcium, phosphorus, alkaline phosphatase, and 25-OHD) of 100 selected patients with ASD were compared with those of the healthy control group. Results Vitamin D deficiency or insufficiency was found in approximately 95% of all patients. Levels of 25-OHD in adolescent patients with ASD aged 11 to 18 years were significantly lower than those in patients aged younger than 11 years. In the 100 selected patients with ASD, mean serum 25-OHD levels were significantly lower and alkaline phosphatase levels were higher compared with those in healthy children. Conclusion Our study suggests a relationship between vitamin D and ASD in children. Monitoring vitamin D levels is crucial in autistic children, especially adolescents, to take protective measures and treat this condition early.

Serum vitamin D in Indian children with vernal keratoconjunctivitis

2021 ◽  
Vol 2 (2) ◽  
pp. 63-68
Author(s):  
Priyanka Singh ◽  
◽  
Anuj Mehta ◽  
L. Sarkar ◽  
◽  
...  
Keyword(s):  
Vitamin D ◽  
Serum Vitamin ◽  
Vernal Keratoconjunctivitis ◽  
Control Group ◽  
Healthy Children ◽  
Indian Children ◽  
Serum Vitamin D ◽  
Severe Deficiency ◽  
Vitamin D Levels ◽  
Ocular Surface Health

AIM: To determine the vitamin D levels in vernal keratoconjunctivitis (VKC) patients in Indian population. METHODS: A total of 30 non-atopic healthy children and 30 children having VKC were included in the study. The serum vitamin D levels and the time spent outside was compared between the two groups (P<0.05). RESULTS: The mean serum vitamin D level in the VKC group was significantly lower (mean 19.17±10.76 ng/mL) compared to the control group (mean 31.19±9.09 ng/mL) (P=0.0003). The vitamin D levels were found to be deficient (10-20 ng/mL) in 43.33%, whereas severe deficiency (<10 ng/mL) was found in 20% of the VKC patients. The deficiency of vitamin D correlated with the level of severity of VKC (P<0.02). The time spent outside in the VKC group was 1.07±0.76h, whereas in the healthy subjects it was 2.08±0.72h (P<0.0001), and it showed a significant correlation with the serum 25 (OH) D3 levels (r=0.478, P<0.001). CONCLUSION: The study shows that children with VKC had a significantly lower serum vitamin D levels as compared to the healthy children which correlated with time spent outside. The severity of VKC also correlated with the severity of vitamin D deficiency which suggests that vitamin D plays an important role in maintaining ocular surface health.

scholarly journals Role of vitamin D, serum zinc, and serum iron deficiency in community-acquired pneumonia in children

2021 ◽  
Vol 69 (1) ◽  
Author(s):  
Asmaa Alhusseiny Ahmed Alsharkawy ◽  
Ahmed R. Rezk
Keyword(s):  
Vitamin D ◽  
Serum Iron ◽  
Serum Zinc ◽  
Community Acquired Pneumonia ◽  
Control Group ◽  
Iron Level ◽  
Healthy Children ◽  
Serum Iron Level ◽  
Vitamin D Levels ◽  
Significant Difference

Abstract Background Community-acquired pneumonia is a major cause of death among children. Inadequate nutrition disrupts the immune system and increases the susceptibility to infections. We aimed to evaluate the association between vitamin D, serum zinc, and iron, and pneumonia. A case-control study was conducted at the outpatient clinic and emergency room of Children’s Hospital. Thirty-one patients with community-acquired pneumonia and 36 healthy children (control group) underwent serum sampling for vitamin D, zinc, and iron. Results Most patients had mild form (n = 17, 54.8%). All patients survived and were discharged. The serum iron level showed a non-significant difference between pneumonia and control groups (p ˃ 0.05). TIBC, vitamin D, and serum zinc were significantly lower in the patient group than the control group (P value = 0.04, < 0.001, and 0.03, respectively). Vitamin D deficiency was highly associated with the severity of pneumonia (P value = 0.008). Conclusion Adequate serum zinc and vitamin D levels may be protective against infection with community-acquired pneumonia in children aged from 2 months to 5 years old, but not iron.

scholarly journals Correlation between vitamin D levels and bone metabolism in children with cow’s milk allergy

2022 ◽  
Vol 50 (1) ◽  
pp. 030006052110660
Author(s):  
Di Che ◽  
Li Yu ◽  
Yong Guo ◽  
Hai-jin Ke ◽  
Cui Liu ◽  
...  
Keyword(s):  
Vitamin D ◽  
Risk Factor ◽  
Bone Metabolism ◽  
Vitamin D Deficiency ◽  
Cow’S Milk ◽  
Control Group ◽  
Healthy Children ◽  
Serum Calcitonin ◽  
Cow's Milk ◽  
Vitamin D Levels

Objective Research is limited regarding biochemical markers of bone metabolism among children with cow’s milk protein allergy (CMPA). We aimed to determine differences in vitamin D and bone metabolism markers between infants with CMPA and healthy infants and explore relationships between these in a cross-sectional study. Methods In total, we included 41 children diagnosed with CMPA and under systematic medical and nutritional care at our center, and 50 healthy children as a control group. We reviewed demographic and clinical characteristics and measured serum biomarkers. Results We found that serum 25-hydroxyvitamin D (25(OH)D) levels among infants in the CMPA group were significantly lower than those in the control group, and levels of bone-specific alkaline phosphatase (BALP), serum phosphorus, and serum calcitonin were reduced. Pearson correlation analysis showed that serum 25(OH)D concentrations in the CMPA group were negatively correlated with parathyroid hormone but not significantly correlated with calcitonin and BALP. Logistic regression showed that CMPA was a risk factor for vitamin D deficiency. Conclusions Our study indicated that CMPA was associated with disturbances in bone metabolism. Levels of vitamin D in children with CMPA were lower than those in healthy children. CMPA was a risk factor for vitamin D deficiency.

Evaluation of serum 25-hidroxy vitamin D and zinc levels in asthmatic patients

2017 ◽  
Vol 43 (1) ◽  
pp. 49-56 ◽  
Author(s):  
Murat Elevli ◽  
Ayşe Ergül Bozacı ◽  
Kamil Şahin ◽  
Hatice Nilgün Duru ◽  
Mahmut Çivilibal ◽  
...  
Keyword(s):  
Vitamin D ◽  
Body Height ◽  
Serum Zinc ◽  
Atopic Asthma ◽  
Control Group ◽  
Healthy Children ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
Zinc Levels ◽  
The Impact

AbstractIntroduction:We aimed to investigate the impact of serum zinc, and vitamin D levels on the development of asthma, and its clinical characteristics.Methods:In our cross-sectional study; 50 patients who were diagnosed as atopic asthma and 70 healthy children consisted the control group. In both groups levels of vitamin D, and zinc were analyzed.Results:A statistically significant intergroup difference was not detected as for age, gender, body height (percentile), and weight (percentile) of the patients (p>0.05). Mean vitamin D levels in the asthmatic patient, and control groups were 32.61±9.48 nmol/L, and 42.55±15.42 nmol/L, respectively. Between two groups a statistically significant difference was found (p=0.001). Zinc levels were higher in the control group without any statistically significant difference between groups (p=0.25). A statistically significant negative correlation (−0.635) was found between vitamin D levels, and severity of asthma in the patient group. As the level of vitamin D increased, a decrease in severity of asthma was seen (p=0.04).Conclusion:Though larger series are needed to arrive at definitive conclusions, we think that vitamin D deficiency rather than zinc deficiency, might convey importance in the emergence, and exacerbation of asthma.

scholarly journals Association of Vitamin D Deficiency with Acute Lower Respiratory Infection in Toddlers

2016 ◽  
Vol 36 (1) ◽  
pp. 14-16 ◽  
Author(s):  
Gursharan Singh Narang ◽  
Sunita Arora ◽  
Sahiba Kukreja ◽  
Dr Shifali
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Univariate Analysis ◽  
Significant Risk ◽  
World Health ◽  
Control Group ◽  
Acute Lower Respiratory Infection ◽  
Healthy Children ◽  
Severe Vitamin

Introduction: Pneumonia remains a significant health problem in India with significant morbidity and mortality. Objectives of this study were to identifying an effective nutritional agent that reduces the need for antibiotics, duration of pneumonia and length of hospitalization would be highly cost-beneficial.Material and Methods: This was a hospital-based case-control study: A total of 100 children including 50 cases and 50 controls, aged 2–60 months, were enrolled. Case definition of severe ALRI as given by the World Health Organization was used for cases. Controls were healthy children attending outpatients’ service for immunization or admitted for minor ailments other than ALRTI.Results: Mean 25(OH)D concentrations in children of the study group were lower than those of the control group (20.431 ng/mL vs. 27.67 ng/mL; p = 0.035). Factors significantly associated with decreased risk of ALRTI in univariate analysis were: exclusive breastfeeding in the first 6 months (cases 13/50 (26%), controls 42/50 (84%); p=0.000); adequate exposure to sunlight (cases 14/50 (28%), controls 42/50 (84%); P=0.000); and serum 25OHD3 <20 ng/ml (cases 28/50 (56%), controls 0/50 (0%); p=.000). Multivariate logistic model indicated that severe vitamin D deficiency (OR=NA), exclusive breast feeding (OR=.174); 95% CI (.061- .521; p=.002) and adequate sunlight exposure (OR=.179) ;95%CI (.062-.519); p=.002) were significant independent predictive risk factors for ALRTI among the children between 2 months – 5 years of age (all p<0.05).Conclusion: Severe vitamin D deficiency (<20ng/ml), nonexclusive breastfeeding in the first six months of life, inadequate sun exposure were significant risk factors for ALRTI in Indian children.J Nepal Paediatr Soc 2016;36(1):14-18

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