scholarly journals Proposal of a Preoperative CT-Based Score to Predict the Risk of Clinically Relevant Pancreatic Fistula after Cephalic Pancreatoduodenectomy

Medicina ◽  
2021 ◽  
Vol 57 (7) ◽  
pp. 650
Author(s):  
Marius Lucian Savin ◽  
Florin Mihai ◽  
Liliana Gheorghe ◽  
Corina Lupascu Ursulescu ◽  
Dragos Negru ◽  
...  

Background and Objectives: Postoperative pancreatic fistula after cephalic pancreatoduodenectomy (CPD) is still the leading cause of postoperative morbidity, entailing long hospital stay and costs or even death. The aim of this study was to propose the use of morphologic parameters based on a preoperative multisequence computer tomography (CT) scan in predicting the clinically relevant postoperative pancreatic fistula (CRPF) and a risk score based on a multiple regression analysis. Materials and Methods: For 78 consecutive patients with CPD, we measured the following parameters on the preoperative CT scans: the density of the pancreas on the unenhanced, arterial, portal and delayed phases; the unenhanced density of the liver; the caliber of the main pancreatic duct (MPD); the preoperatively estimated pancreatic remnant volume (ERPV) and the total pancreatic volume. We assessed the correlation of the parameters with the clinically relevant pancreatic fistula using a univariate analysis and formulated a score using the strongest correlated parameters; the validity of the score was appreciated using logistic regression models and an ROC analysis. Results: When comparing the CRPF group (28.2%) to the non-CRPF group, we found significant differences of the values of unenhanced pancreatic density (UPD) (44.09 ± 6.8 HU vs. 50.4 ± 6.31 HU, p = 0.008), delayed density of the pancreas (48.67 ± 18.05 HU vs. 61.28 ± 16.55, p = 0.045), unenhanced density of the liver (UDL) (44.09 ± 6.8 HU vs. 50.54 ± 6.31 HU, p = 0.008), MPD (0.93 ± 0.35 mm vs. 3.14 ± 2.95 mm, p = 0.02) and ERPV (46.37 ± 10.39 cm3 vs. 34.87 ± 12.35 cm3, p = 0.01). Based on the odds ratio from the multiple regression analysis and after calculating the optimum cut-off values of the variables, we proposed two scores that both used the MPD and the ERPV and differing in the third variable, either including the UPD or the UDL, producing values for the area under the receiver operating characteristic curve (AUC) of 0.846 (95% CI 0.694–0.941) and 0.774 (95% CI 0.599–0.850), respectively. Conclusions: A preoperative CT scan can be a useful tool in predicting the risk of clinically relevant pancreatic fistula.

Author(s):  
Muhammad Shahid Iqbal ◽  
Fahad I. Al-Saikhan ◽  
Nehad J. Ahmed ◽  
Muhammad Zahid Iqbal

Aims: This study aimed to assess the current levels of job and workplace satisfaction among community pharmacists (CPs) and to explore the factors that can affect their job and workplace satisfaction. Methods: A self-administered research tool (questionnaire) was developed based on previously published literature. After its reliability and validity measurements, the questionnaire was distributed to the target population and data was collected. Data were entered into Statistical Package for Social Science (SPSS) ver. 22.0 and analyzed using descriptive statistics, chi-square, and multiple regression analysis. The level of significance (α) was set at 0.05. Results: CPs reported high satisfaction (76.7%) concerning their jobs. Only 23.3% of them were not satisfied with their current job. Univariate analysis showed that job and workplace satisfaction among CPs was not significantly associated with gender, age, length of service, position and salary. However, the univariate analysis demonstrated a significant difference between practice settings and job and workplace satisfaction with p = 0.013. Among the respondents, those who worked in the chain pharmacies (83.7%) expressed greater job and workplace satisfaction, which is 16% higher than those working in independent pharmacies (67.6%). Therefore, practice setting was shown as the predictor of job and workplace satisfaction among CPs by using multiple regression analysis. Conclusion: Overall, CPswere relatively satisfied with their current job. Our results had reinforced previous studies that reported that practice settings can affect pharmacists’ job and workplace satisfaction.


2021 ◽  
Author(s):  
Xia Wu ◽  
Zhiling Li ◽  
Wenjiang Sun ◽  
Huan Zheng

Polycystic ovary syndrome (PCOS) is associated with an increased risk of cardiovascular disease in women. Hyperhomocysteinemia (H-Hcy) is closely related to arterial stiffness (AS) in patients with cardiovascular disease. This study aimed to investigate the relationship between serum homocysteine (Hcy) level and brachial-ankle pulse wave velocity (baPWV) in Chinese women with PCOS. A total of 124 PCOS women were enrolled and divided into two groups according to their baPWV values: normal, baPWV <1400 cm/s; and high AS, baPWV ≥1400 cm/s. Univariate analysis was performed to investigate the relative factors for baPWV, and multiple regression analysis was used to evaluate the association of Hcy with baPWV. The group with high AS(n=35) had higher Hcy levels than the other group (n=89; P<0.05). Moreover, univariate analysis revealed that serum Hcy was positively correlated with baPWV (r = 0.133, P<0.01). In multiple regression analysis, the age-adjusted serum Hcy level was positively correlated with baPWV (β = 0.201, P<0.01). It remained positively associated with baPWV (β = 0.145, P<0.01) after further adjustments for age, body mass index, PCOS duration, systolic blood pressure and homeostasis model assessment-insulin resistance as well as several other factors correlated with baPWV. Our results demonstrated that H-Hcy was significantly and independently related to elevated baPWV, suggesting that Hcy might play a role in the pathologic process of AS in women with PCOS. Further researches with more subjects are needed to explore whether Hcy would be a promising biomarker for stratification management of PCOS women.


2017 ◽  
Vol 24 (2) ◽  
pp. 144-153
Author(s):  
Yunita Fitri Wahyuningtyas

This research is conducted upon the emergence of many companies producing the same product of the same kind and function. It leads to the urgency of proper and well planned marketing strategy. This research aims to investigate how far the influence of branding, product quality, and price toward consumer’s satisfaction in beverage franchise business. This research utilizes 5 likert scale questionnaire which is tested by using multiple regression analysis to reveal whether or not there is partial and simultaneous influence of branding, product quality, and price toward consumer’s satisfaction in beverage franchise business. Sampling method is accidental sampling technique, in which sample of particular population is taken based on the accessibility and availability of the sample during the sampling process. Sample used is 100 samples among consumers or customers of Mang Endy Milkshake. The result shows that branding, product quality, and price influence consumer’s satisfaction in beverage franchise business.


2018 ◽  
Vol 9 (9) ◽  
pp. 825-832
Author(s):  
James M. Alin ◽  
◽  
Datu Razali Datu Eranza ◽  
Arsiah Bahron ◽  
◽  
...  

Seaweed-Kappaphycus-Euchema Cottonii and Denticulum species was first cultivated at Sabah side of Sebatik in 2009. By November 2014, sixty one Sabahan seaweed farmers cultivated 122 ha or 3,050 long lines. Thirty Sabahan seaweed farmers in Kampung Pendekar (3.2 m.t dried) and 31 in Burst Point (12.5 m.t dried) produced 16 metric tonnes of dried seaweed contributed 31% to Tawau’s total production (51 m.t). The remaining 69% were from farmers in Cowie Bay that separates Sebatik from municipality of Tawau. Indonesian in Desa Setabu, Sebatik started in 2008. However, the number of Indonesian seaweed farmers, their cultivated areas and production (as well as quality) in Sebatik increased many times higher and faster than the Sabah side of Sebatik. In 2009 more than 1,401 households in Kabupaten Nunukan (including Sebatik) cultivated over 700 ha and have produced 55,098.95 and 116, 73 m.t dried seaweed in 2010 and 2011 respectively. There is a divergence in productions from farming the sea off the same island under similar weather conditions. Which of the eight explanatory factors were affecting production of seaweeds in Sebatik? Using Cobb Douglas production function, Multiple Regression analysis was conducted on 100 samples (50 Sabahan and 50 Indonesian). Results; Variable significant at α = 0.05% are Experience in farming whereas Farm size; Quantity of propagules and Location — Dummy are the variables significant at α 0.01%. Not significant are variables Fuel; Age; Number of family members involved in farming and Education level.


2019 ◽  
Vol 7 (1) ◽  
pp. 72-78
Author(s):  
Ismalia Prambayu ◽  
Mulia Sari Dewi

AbstractInternet addiction has become a worrying phenomenon for Indonesian teenagers. This research was conducted to determine whether the psychological factors will influence internet addiction in adolescents. This research uses quantitative with multiple regression analysis method. The winning sample is 200 adolescents. The instrument collects data using a scale internet addiction scale that compiled by Griffiths (2005) and developed by Lemmens (2009), Parenting Authority Questionnaire (PAQ) developed by Buri (1991), Social Skill Inventory (SSI) developed by Riggio (1986), and A Rasch-Type Loneliness Scale compiled by De Jong Gierveld (2006).  The results showed that there were significant differences in the parenting style, social skills, and loneliness on the tendency of internet addiction in adolescents.AbstrakAdiksi Internet menjadi salah satu fenomena yang mengkhawatirkan untuk remaja Indonesia. Penelitian ini dilakukan untuk mengetahui faktor psikologis apakah yang memberikan pengaruh terhadap kecenderungan adiksi internet pada remaja. Sampel pada penelitian ini berjumlah 200 remaja dengan menggunakan metode analisis kuantitatif. Penelitian ini menggunakan alat ukur sebagai berikut, alat ukur adiksi internet yang dikembangkan oleh Lemmens (2009), Parenting Authority Questionnaire (PAQ) yang dikembangkan oleh Buri (1991), Social Skill Inventory (SSI) yang dikembangkan oleh Riggio (1986), dan A Rasch-Type Loneliness Scale yang disusun oleh De Jong Gierveld (2006). Berdasarkan hasil pengujian ditemukan pengaruh signifikan gaya pengasuhan, keterampilan sosial, dan kesepian terhadap kecenderungan adiksi internet pada remaja.


2020 ◽  
Author(s):  
Vebi Deswanto

The purpose of this research is to analyza the influence of work motivation and training on the performance of the employees at the Education and Culture Office Of Padang Pariaman Regency. In this study using descriptive analisys. This analysis is to strengthen the argumentation and logic in answering and implementing allegations that will be described in quantitative analysis, for testing this research hypothesis, including multiple regression analysis. The result of this study illustrate that all variables affect the performance of employees. The result of this research where the variable of work motivation (X1) is known equal to 1,670 then training variable (X2) is obtained equal to 1,670, for employee performance result (Y) equal to 33,196. It can be concluded that the motivation of work ad training is influential in improving the performance of employees within the Department of Education and Culture of Padang Pariaman Regency.


2020 ◽  
Author(s):  
Ha Nam Khanh Giao

The research investigates how the factors affect Vietnamese consumers attitude on television advertisement of skin care, by intervewing 280 consumers. The method of Cronbach’s Alpha analysis, EFA analysis and multiple regression analysis were used with the SPSS program.The result shows that the affects of the factors on Vietnamese buyer’s behavior about TV commercial of skin care increasingly: Entertaiment, Informativeness, Celebrity, In-irritation, Credibility. The research also suggests some solutions to the television advertisers to enhance capability of serving consumers.attitude on television advertisement, Vietnamese consumers, skin care


2020 ◽  
Author(s):  
Ha Nam Khanh Giao

The paper examines relation between Vietnam Airline Domestic service quality and customer satisfaction by gathering opinions from 402 passengers employing Skytrax scale with some modification along with Cronbach’s alpha, EFA and multiple regression analysis. Results show that Vietnam Airline Domestic service quality can be measured by the following six determinants in order of decreasing importance: (1) boarding/deplaning/baggage; (2) check in; (3) in-flight services; (4) reservation; (5) aircraft; and (6) flight crew. All of them are directly proportional effect to customer satisfaction. The paper also offers some suggestions to improve the service quality thereby enhancing the customer satisfaction.


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