scholarly journals High Flow-Rate Sample Loading in Large Volume Whole Water Organic Trace Analysis Using Positive Pressure and Finely Ground Sand as a SPE-Column In-Line Filter

Molecules ◽  
2019 ◽  
Vol 24 (7) ◽  
pp. 1426
Author(s):  
Ola Svahn ◽  
Erland Björklund
Keyword(s):  
Physicochemical Properties ◽  
Flow Rate ◽  
Solid Phase ◽  
Pure Water ◽  
Maximum Flow ◽  
Maximum Flow Rate ◽  
Positive Pressure ◽  
Flow Rates ◽  
Relative Standard ◽  
Whole Water

By using an innovative, positive pressure sample loading technique in combination with an in-line filter of finely ground sand the bottleneck of solid phase extraction (SPE) can be reduced. Recently published work by us has shown the proof of concept of the technique. In this work, emphasis is put on the SPE flow rate and method validation for 26 compounds of emerging environmental concern, mainly from the 1st and 2nd EU Watch List, with various physicochemical properties. The mean absolute recoveries in % and relative standard deviations (RSD) in % for the investigated compounds from spiked pure water samples at the three investigated flow rates of 10, 20, and 40 mL/min were 63.2% (3.2%), 66.9% (3.3%), and 69.0% (4.0%), respectively. All three flow rates produced highly repeatable results, and this allowed a flow rate increase of up to 40 mL/min for a 200 mg, 6 mL, reversed phase SPE cartridge without compromising the recoveries. This figure is more than four times the maximum flow rate recommended by manufacturers. It was indicated that some compounds, especially pronounced for the investigated macrolide molecules, might suffer when long contact times with the sample glass bottle occurs. A reduced contact time somewhat decreases this complication. A very good repeatability also held true for experiments on both spiked matrix-rich pond water (high and low concentrations) and recipient waters (river and wastewater) applying 40 mL/min. This work has shown that, for a large number of compounds of widely differing physicochemical properties, there is a generous flow rate window from 10 to 40 mL/min where sample loading can be conducted. A sample volume of 0.5 L, which at the recommended maximum flow rate speed of 10 mL/min, would previously take 50 min, can now be processed in 12 min using a flow rate of 40 mL/min. This saves 38 min per processed sample. This low-cost technology allows the sample to be transferred to the SPE-column, closer to the sample location and by the person taking the sample. This further means that only the sample cartridge would need to be sent to the laboratory, instead of the whole water sample, like today’s procedure.

Transport of Particle-Laden Fluids Through Fixed-Valve Micropumps

1999 ◽  
Author(s):  
Ling-Sheng Jang ◽  
Christopher J. Morris ◽  
Nigel R. Sharma ◽  
Ron L. Bardell ◽  
Fred K. Forster
Keyword(s):  
Surface Charge ◽  
Surface Area ◽  
Flow Rate ◽  
Pure Water ◽  
Maximum Flow ◽  
Total Surface Area ◽  
Maximum Flow Rate ◽  
Number Density ◽  
Polystyrene Microspheres ◽  
Negative Surface

Abstract Micropumps designed for the flow-rate range of 100–1000μl/min have been developed by a number of research groups. However, little data is available regarding the ability of various designs to directly transport liquids containing particles such as cells, microspheres utilized for bead chemistry, or contaminants. In this study the ability of pumps with no-moving-parts valves (NMPV) to transport particles was investigated. The results showed that a NMPV micropump was able to directly pump suspensions of polystyrene microspheres from 3.1 to 20.3μm in diameter. The pump functioned without clogging at microsphere number densities as high as 9000 particles/μl of suspension, which corresponded to over 90,000 particles per second passing through the pump at a flow rate of 600μl/min. Performance with polystyrene microspheres was the same as pure water up to the point of cavitation. Microspheres manufactured with negative surface charge cavitated less readily that other microspheres studied that were manufactured without surface charge. However, cavitation did not appear to be a function of microsphere size, total surface area or number density. Thus pumping polystyrene microspheres was found to be more affected by surface effects than by size, surface area or number density within the range of parameters considered. In the case of charged microspheres, the maximum flow rate was reduced by 30% compared to pure water whereas for uncharged microspheres the maximum flow rate was reduced by approximately 80%.

Design and Fabrication of PDMS/PMMA-Based Rotary Micropump

2016 ◽  
Vol 829 ◽  
pp. 29-34 ◽  
Author(s):  
Lung Ming Fu ◽  
Wen Teng Wang ◽  
Chia Yen Lee
Keyword(s):  
Flow Rate ◽  
Rotational Velocity ◽  
Maximum Flow ◽  
Maximum Flow Rate ◽  
Engine Oil ◽  
Working Fluid ◽  
Flow Rates ◽  
Peristaltic Pumping ◽  
Velocity Flow ◽  
Pdms Microchannel

A novel micropump is proposed comprising a PMMA-based rotor, a circular PDMS micro-chamber, and a semi-circular PDMS microchannel connecting the inlet and outlet reservoirs as the rotor spins, a plug of sample fluid is trapped within the microchannel between neighboring blades of the rotor and is driven through the channel toward the outlet. Meanwhile, the rotors periodically compress and release the inlet and outlet regions of the microchannel. Thus, as the rotor turns, one plug of sample fluid is drawn into the microchannel as another is ejected into the outlet reservoir. In other words, a peristaltic pumping effect is achieved. It is shown that the flow rate in the proposed device can be controlled simply by adjusting the rotational velocity of the rotor. A maximum flow rate of 1.22 ml/min is obtained given de-ionized water as the working fluid and a rotational velocity of 232 rpm. Moreover, given the same rotational velocity, flow rates of 0.724 ml/min and 0.336 ml/min are obtained for salad oil and engine oil, respectively.

Lichen sclerosis–induced long segment anterior urethral stricture: The early outcome of one-stage repair using dorsolateral onlay buccal mucosa graft

2021 ◽  
pp. 039156032110033
Author(s):  
Atef Fathi ◽  
Omar Mohamed ◽  
Osama Mahmoud ◽  
Gamal A Alsagheer ◽  
Ahmed M Reyad ◽  
...  
Keyword(s):  
Success Rate ◽  
Urethral Stricture ◽  
Flow Rate ◽  
Urine Volume ◽  
Maximum Flow ◽  
Maximum Flow Rate ◽  
P Value ◽  
Onlay Graft ◽  
Voiding Symptoms ◽  
Stricture Recurrence

Background: Substitution urethroplasty using buccal mucosal grafts can be performed by several approaches including ventral onlay graft, dorsal onlay graft, or ventral urethrotomy with dorsal inlay graft. Our study aims to evaluate the surgical outcome of dorsolateral buccal mucosal graft for long segment anterior urethral stricture >6 cm in patients with Lichen sclerosus (LS). Methods: A retrospective study included patients who underwent repair for long segment anterior urethral stricture >6 cm due to LS between January 2013 and April 2019. All patients were followed-up at 3, 6, 9, and 12 months postoperatively and then yearly by clinical symptoms, uroflowmetry, and calculation of post-void residual urine volume. Retrograde urethrogram was requested for patients with voiding symptoms or decreased maximum flow rate. Stricture recurrence that required subsequent urethrotomy or urethroplasty was considered failure. The success rate and surgical complications were collected and analyzed. Results: Thirty patients were identified. The median age (range) was 39 (25–61) years and a median (range) stricture length was 8 (6–14) cm. Most of postoperative complications were of minor degree. The success rate at median follow-up of 15 (12–24) months was 86.5%. The median maximum flow rate increased significantly from 6 (2–11) ml/s preoperatively to 18 (range: 6–23) ml/s at the 6th month ( p value < 0.001). Conclusion: Dorsolateral buccal mucosal grafts urethroplasty for long anterior urethral stricture caused by LS has a high success rate and low risk of complications including stricture recurrence.

scholarly journals Maximum Flow Rate of a Single Component, Two-Phase Mixture

1965 ◽  
Vol 87 (1) ◽  
pp. 134-141 ◽  
Author(s):  
F. J. Moody
Keyword(s):  
Flow Rate ◽  
Static Pressure ◽  
Maximum Flow ◽  
Single Component ◽  
Maximum Flow Rate ◽  
Vapor Flow ◽  
Two Phase ◽  
Slip Ratio ◽  
Phase Mixture ◽  
Local Slip

A theoretical model is developed for predicting the maximum flow rate of a single component, two-phase mixture. It is based upon annular flow, uniform linear velocities of each phase, and equilibrium between liquid and vapor. Flow rate is maximized with respect to local slip ratio and static pressure for known stagnation conditions. Graphs are presented giving maximum steam/water flow rates for: local static pressures between 25 and 3,000 psia, with local qualities from 0.01 to 1.00; local stagnation pressures and enthalpies which cover the range of saturation states.

Effect of Blade Angle of Attack and Hub to Tip Ratio on Mass Flow Rate in an Axial Fan at a Fixed Rotational Speed

2008 ◽  
Author(s):  
Mohammad J. Izadi ◽  
Alireza Falahat
Keyword(s):  
Mass Flow Rate ◽  
Mass Flow ◽  
Flow Rate ◽  
Rotational Speed ◽  
Angle Of Attack ◽  
Maximum Flow ◽  
Maximum Flow Rate ◽  
Maximum Mass ◽  
Blade Angle ◽  
Axial Fan

In this investigation an attempt is made to find the best hub to tip ratio, the maximum number of blades, and the best angle of attack of an axial fan with flat blades at a fixed rotational speed for a maximum mass flow rate in a steady and turbulent conditions. In this study the blade angles are varied from 30 to 70 degrees, the hub to tip ratio is varied from 0.2 to 0.4 and the number of blades are varied from 2 to 6 at a fixed hub rotational speed. The results show that, the maximum flow rate is achieved at a blade angle of attack of about 45 degrees for when the number of blades is set equal to 4 at most rotational velocities. The numerical results show that as the hub to tip ratio is decreased, the mass flow rate is increased. For a hub to tip ratio of 0.2, and an angle of attack around 45 degrees with 4 blades, a maximum mass flow rate is achieved.

The characters exploration of a piezoelectric pump with fishtail-shaped bluffbody

2021 ◽  
pp. 1045389X2110386
Author(s):  
Yi Hou ◽  
Lipeng He ◽  
Zheng Zhang ◽  
Baojun Yu ◽  
Hong Jiang ◽  
...  
Keyword(s):  
Flow Rate ◽  
Preliminary Investigation ◽  
Maximum Flow ◽  
Theoretical Explanation ◽  
Maximum Flow Rate ◽  
Bluff Bodies ◽  
Conical Flow ◽  
Piezoelectric Pump ◽  
Valveless Piezoelectric Pump ◽  
Shape And Size

This paper focuses on a new structure in the valveless piezoelectric pump, which has a combination structure of the conical flow channel and two fishtail-shaped bluffbodies in the chamber of the pump. The fishtail-shaped bluffbody is inspired by the shape of the swimming fish to diminish the backflow and optimize the performance of the pump. The performance is studied by changing the shape and size of the inlet and outlet, the bluff bodies’ height and the space between two bluff bodies. The results show that the 3 mm × 3 mm square inlet, 3 mm diameter round outlet, 3 mm height of bluffbodies, 6.8 mm pitch of bluffbodies has a best performance in all 10 prototypes, which implements a maximum flow rate of 87.5 ml/min at 170 V 40 Hz with a noise of 42.6 dB. This study makes a preliminary investigation and theoretical explanation for the subsequent optimization of this structure, improved the performance of the valveless piezoelectric pump, broaden the thinking of the design for the bluffbody for better performance of the valveless piezoelectric pump.

A New Method for Performance Measurement of PPV Fans for Fire Fighting Under Realistic Conditions

2020 ◽  
Author(s):  
Michael Steppert ◽  
Philipp Epple ◽  
Michael Steber ◽  
Stefan Gast
Keyword(s):  
Design Process ◽  
Flow Rate ◽  
Volumetric Flow Rate ◽  
Navier Stokes ◽  
Analytical Relation ◽  
Positive Pressure ◽  
Flow Rates ◽  
Free Jet ◽  
Actual Flow Rate ◽  
Coefficient Of Discharge

Abstract PPV Fans (Positive Pressure Ventilation Fans) are used in firefighting to remove smoke from a burning building, so that fire fighters can have a clear view inside the house and injured people do not have to breathe toxic smoke. This can be done by placing a PPV fan in a distance of about two meters in front of a door of the burning building. On another, carefully chosen position in the building, e. g. a window, a door or at the roof an opening has to be created, where the smoke can leave the building. The same volumetric flow rate of gas that is blown into the building by the PPV fan has to leave the building at a chosen opening. Because the gas entering the building is air and the gas leaving the building is a mixture of smoke and air, the smoke concentration in the building can be reduced. To test the performance of such PPV fans, a test building with a door in the first floor and a window in the 3rd floor has been built. To measure the volumetric flow rate of the smoke and air mixture through the window in the 3rd floor that is leaving the building, a flow meter nozzle was designed. The design process was done using the commercial Navier Stokes solver Star CCM+, where three nozzle designs, such as a nozzle with constant velocity increase, a quarter circle nozzle and a non-curved nozzle were investigated for different volumetric flow rates. Also, a rounding at the window, where the nozzle is placed, was investigated to prevent flow detachment and shock losses at the inlet of the nozzle. The volumetric flow rate through the nozzle can be calculated, by measuring the pressure at the nozzle wall (before the contraction) and applying Bernoulli’s law, the continuity equation and assuming atmospheric pressure at the free jet flow at the end of the nozzle. The so calculated volumetric flow rate was compared with the actual flow rate, given by the numerical CFD simulations. With these values, the nozzle specific coefficient of discharge for several volumetric flow rates has been calculated and a function fitting was done to get obtain analytical relation between pressure and volumetric flow rate. The detailed design process of the three nozzles, the numerical results of the CFD studies and the determination of the nozzle specific coefficients of discharge are shown and discussed in detail in this work.

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