scholarly journals Seeing the Unseen of the Combination of Two Natural Resins, Frankincense and Myrrh: Changes in Chemical Constituents and Pharmacological Activities

Molecules ◽  
2019 ◽  
Vol 24 (17) ◽  
pp. 3076 ◽  
Author(s):  
Bo Cao ◽  
Xi-Chuan Wei ◽  
Xiao-Rong Xu ◽  
Hai-Zhu Zhang ◽  
Chuan-Hong Luo ◽  
...  
Keyword(s):  
Chronic Diseases ◽  
Chemical Constituents ◽  
Chemical Components ◽  
Pharmacological Effects ◽  
Pharmacological Activities ◽  
Channel Characteristics ◽  
Natural Resins ◽  
Ancient Times ◽  
Traditional Natural ◽  
Natural Drugs

For the treatment of diseases, especially chronic diseases, traditional natural drugs have more effective therapeutic advantages because of their multi-target and multi-channel characteristics. Among many traditional natural medicines, resins frankincense and myrrh have been proven to be effective in the treatment of inflammation and cancer. In the West, frankincense and myrrh have been used as incense in religious and cultural ceremonies since ancient times; in traditional Chinese and Ayurvedic medicine, they are used mainly for the treatment of chronic diseases. The main chemical constituents of frankincense and myrrh are terpenoids and essential oils. Their common pharmacological effects are anti-inflammatory and anticancer. More interestingly, in traditional Chinese medicine, frankincense and myrrh have been combined as drug pairs in the same prescription for thousands of years, and their combination has a better therapeutic effect on diseases than a single drug. After the combination of frankincense and myrrh forms a blend, a series of changes take place in their chemical composition, such as the increase or decrease of the main active ingredients, the disappearance of native chemical components, and the emergence of new chemical components. At the same time, the pharmacological effects of the combination seem magically powerful, such as synergistic anti-inflammation, synergistic anticancer, synergistic analgesic, synergistic antibacterial, synergistic blood-activation, and so on. In this review, we summarize the latest research on the main chemical constituents and pharmacological activities of these two natural resins, along with chemical and pharmacological studies on the combination of the two.

scholarly journals The combination of two natural medicines, Chuanxiong and Asarum: A review of the chemical constituents and pharmacological activities

2021 ◽  
pp. 174751982110391
Author(s):  
Qingcheng Yang ◽  
Fangli Shen ◽  
Fengqin Zhang ◽  
Xue Bai ◽  
Yanru Zhang ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Experimental Studies ◽  
Chemical Components ◽  
Therapeutic Effects ◽  
Anticancer Activities ◽  
Volatile Oils ◽  
Pharmacological Activities ◽  
Single Drug ◽  
Traditional Natural ◽  
Natural Medicines

Traditional Chinese medicine has been clinically used in China for many years, with experimental studies and clinical trials having demonstrated that it is safe and valid. Among many traditional natural medicines, Chuanxiong and Asarum have been proven to be effective in the treatment of relieving pain. Actually, as well as analgesic, they have common attributes, such as anti-inflammatory, cardiovascular benefits, and anticancer activities, with volatile oils being their major components. Furthermore, Chuanxiong and Asarum have been combined as drug pairs in the same prescription for thousands of years, with examples being Chuanxiong Chatiao San and Chuanxiongxixintang. More interestingly, their combination has better therapeutic effects on diseases than a single drug. After the combination of Chuanxiong and Asarum forms a blend, a series of changes take place in their chemical components, such as the contents of the main active ingredients, ferulic acid and ligustilide, increased significantly after this progress. At the same time, the pharmacological effects of the combination appearing to be more powerful, such as synergistic analgesic. This review focuses on the chemical constituents and pharmacological activities of Chuanxiong, Asarum, and Chuanxiong Asarum compositions.

scholarly journals Gmelina arborea: chemical constituents, pharmacological activities and applications

2017 ◽  
Vol 9 (4) ◽  
pp. 528 ◽  
Author(s):  
Charu Arora ◽  
Vinita Tamrakar
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
Iridoid Glycoside ◽  
Immunomodulatory Activity ◽  
Gmelina Arborea ◽  
Β Cells ◽  
Pharmacological Activities ◽  
Flavone Glycoside ◽  
Ancient Times ◽  
Medicinal Properties

<p><em>Gmelina arborea </em>(<em>G. arborea</em>) is a bio-prospective plant belonging to family verbenaceae. It is widely used for it’s medicinal properties from ancient times. The present paper comprehensively reviewed the traditional uses, medicinal properties and chemical constituents isolated from <em>G. arborea</em> based on literature reported as well as critical analysis of the research. The present article is aimed to provide information on recent advances and new foundations and direction for further exploring <em>G. arborea </em>for its applications. Pharmacological research reviewed that <em>G. arborea </em>possess various medicinal properties and biological  activities including antidiuretic, antidiarrhoeal, antipyretic, antianalgesic, antioxidant, antidiabetic, antihelmintic, antibacterial, antifungal, cardiopotective, insecticidal, antiulcer, gastro-protective, anticancer, antihyperlipidemic and immunomodulatory activity. It has been reported for its applications in treatment of bone fracture, hypertension and regeneration of β-cells. The main chemical constituents of <em>G. arborea</em> include lignans, iridoid glycoside, flavonoids, flavons, flavone glycoside and sterols. The present review provides all the references and beneficial directions to explore further application of <em>G. arborea.</em></p>

scholarly journals Scutellaria barbata: A Review on Chemical Constituents, Pharmacological Activities and Clinical Applications

2020 ◽  
Vol 26 (1) ◽  
pp. 160-175 ◽  
Author(s):  
Qiong Chen ◽  
Khalid Rahman ◽  
Su-Juan Wang ◽  
Shuang Zhou ◽  
Hong Zhang
Keyword(s):  
Blood Circulation ◽  
Chemical Constituents ◽  
Blood Stasis ◽  
Clinical Applications ◽  
In Vivo Studies ◽  
Chemical Components ◽  
Pharmacological Activities ◽  
Scutellaria Barbata ◽  
Pharmacologically Active

Scutellaria barbata has a long history of medical use in Traditional Chinese Medicine for removing heat and toxic material, promoting blood circulation and removing blood stasis, and inducing diuresis to reduce edema. Recent pharmacology investigations have provided evidence for its anti-cancer, bacteriostasis, anti-virus, anti-inflammation, anti-oxidation and immunity enhancement properties. The efficacy of activating blood circulation and removing blood stasis has unique advantages in the treatment of cardiovascular and cerebrovascular diseases. A total of 84 compounds have been isolated from S. barbata and are characterized mainly as flavonoids, diterpenoids, followed by polysaccharide, volatile oil and steroids. Peer-reviewed articles published over the last few years were gathered by consulting the databases PubMed, Elsevier, Springer, and Chinese Herbal Classics. This review mainly focuses on the pharmacologically active constituents isolated from S. barbata，which have been subjected to in vitro and/or in vivo studies. Although, the chemical components, pharmacological activities, toxicology, clinical applications and mechanisms of action of S. barbata have been investigated, many constituents remain unknown. Further investigations are required to investigate the medicinal properties of S. barbata.

scholarly journals CHEMICAL CONSTITUENTS AND PHARMACOLOGICAL ACTIVITIES OF LANTANA CAMARA – A REVIEW

2019 ◽  
pp. 10-20
Author(s):  
ALI ESMAIL AL-SNAFI
Keyword(s):  
Chemical Constituents ◽  
Lantana Camara ◽  
Pharmacological Effects ◽  
Pharmacological Activities ◽  
Thrombin Inhibition ◽  
Current Review ◽  
Anthraquinone Glycosides ◽  
Wide Range ◽  
Web Science ◽  
Pharmacological Studies

Objective: The review was designed to investigate the traditional uses, chemical constituents and pharmacological effects of Lantana camara. Methods: In the current review, databases including Web Science, Pub Med, Scopus and Science Direct, were searched to investigate the chemical constituents and pharmacological effects of Lantana camara. Results: The plant contained alkaloids, glycosides, steroids, saponins, flavanoids, coumarins, tannins, carbohydrates, hydroxy anthraquinones, anthraquinone glycosides, proteins, phytosteroids, fixed oils, fats, and triterpinoids. Previous pharmacological studies revealed that Lantana camara possessed antimicrobial, antiparasitic, anxiolytic, gastrointestinal, hypoglycemic, cardiovascular, antioxidant, anticancer, antiinflammatory, analgesic, wound healing, antiurolithiatic, hepatoprotective, reproductive, anti–hemorrhoidal, thrombin inhibition and many other effects. Conclusion: Lantana camara represents a promising medicinal plant with a wide range of pharmacological activities that could be utilized in several medical applications because of its effectiveness and safety.

Pharmacological Effects and Chemical Constituents of Bupleurum

2018 ◽  
Vol 19 (1) ◽  
pp. 34-55 ◽  
Author(s):  
Peng Sun ◽  
Yijie Li ◽  
Sheng Wei ◽  
Tingting Zhao ◽  
Yang Wang ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Chemical Constituents ◽  
Healthy Food ◽  
Chemical Components ◽  
Pharmacological Effects ◽  
Volatile Oils ◽  
Triterpenoid Saponins ◽  
Recent Increase ◽  
Radix Bupleuri

Radix Bupleuri has been used in traditional Chinese medicine for thousands of years, with confirmed curative effects. This plant is also used in healthy food and cosmetics. A recent increase in studies of Radix Bupleuri’s chemical constituents (mainly comprising flavonoids, lignins, phenyl propanol derivatives, triterpenoid saponins, and volatile oils) and pharmacological effects motivates the aim of the present study: to review the chemical components and pharmacological effects of Radix Bupleuri. Our review found that Radix Bupleuri exhibits diverse pharmacological effects. More than 281 components have been isolated from Radix Bupleuri, including 15 flavonoids, 430 lignins, 12 phenyl propanol derivatives, 66 triterpenoid saponins, and 158 volatile oils.

scholarly journals Fritillariae Thunbergii Bulbus: Traditional Uses, Phytochemistry, Pharmacodynamics, Pharmacokinetics and Toxicity

2019 ◽  
Vol 20 (7) ◽  
pp. 1667 ◽  
Author(s):  
Hong Li ◽  
Andrew Hung ◽  
Mingdi Li ◽  
Angela Yang
Keyword(s):  
Chemical Constituents ◽  
Blood Rheology ◽  
Chemical Compounds ◽  
Pharmacological Effects ◽  
Historical Records ◽  
Pharmacological Activities ◽  
Traditional Uses ◽  
Anti Cancer ◽  
Pharmacological Studies ◽  
Anti Inflammation

Fritillariae Thunbergii Bulbus (FTB) has been widely used as an antitussive herb for thousands of years in China. However, FTB’s traditional uses, chemical compounds and pharmacological activities have not been systematically reviewed. This study aimed to review its traditional uses, phytochemistry, pharmacodynamics, pharmacokinetics and toxicity. We searched the Encyclopedia of Traditional Chinese Medicine to explore the historical records which indicate that it acts to clear heat, resolve phlegm, relieve cough, remove toxicity and disperse abscesses and nodules. We searched 11 databases to identify potential phytochemical or pharmacological studies. Characteristics of its chemical constituents, pharmacological effects, pharmacokinetic and toxicity were descriptively summarized. A total of 9706 studies were identified and 83 of them were included. As a result, 134 chemical constituents were identified, including 26 alkaloids, 29 compounds found in essential oils, 13 diterpenoids, two carbohydrates, two sterols, 18 amino acids, six nucleosides, four nucleobases, four fatty acids, three lignans, and 27 elements. Thirteen pharmacological effects of FTB were identified, including anti-cancer, tracheobronchial relaxation, antitussive, expectorant, anti-muscarinic, anti-inflammation, anti-thyroid, regulation of blood rheology, antiulcer, anti-diarrhea, pain suppression, antioxidation and neuroprotection. These pharmacological activities may be mainly attributed to the alkaloids in FTB. Further phytochemical, pharmacological and network pharmacological studies are recommended.

scholarly journals Chemical constituents and pharmacological activities of Mirabilis jalapa- A review

2021 ◽  
Vol 1 (2) ◽  
pp. 034-045
Author(s):  
Ali Esmail Al-Snafi ◽  
Tayseer Ali Talab ◽  
Wajdi M. Jabbar ◽  
Ali M. Alqahtani
Keyword(s):  
Cardiac Glycosides ◽  
Chemical Constituents ◽  
Therapeutic Effects ◽  
Pharmacological Effects ◽  
Phytochemical Screening ◽  
Pharmacological Activities ◽  
Current Review ◽  
Wide Range ◽  
Pharmacological Studies ◽  
Mirabilis Jalapa

Mirabilis jalapa was used traditionally in the treatment of kidney infections, as diuretic, tonic, cathartic, purgative and emetic. The phytochemical screening of the extracts of the leaves and stems of the Mirabilis jalaparevealed the presence of tannins, alkaloids, flavonoids, phenolic compounds, carbohydrates, terpenes, glycosides, saponins, protein, cardiac glycosides, steroids and emodin. The previous pharmacological studies revealed that Mirabilis jalapa possessed wide range of pharmacological and therapeutic effects included antimicrobial, antiparasitic, dermatological, anticancer, anti-inflammatory, analgesic, antidiabetic, antihistaminic, immune-modulatory, antispasmodic and many other pharmacological effects. The chemical constituents, nutritional, pharmacological and therapeutic effects ofMirabilis jalapawere discussed in the current review.

scholarly journals Active Components and Pharmacological Effects of Cornus officinalis: Literature Review

2021 ◽  
Vol 12 ◽  
Author(s):  
Xue Gao ◽  
Yi Liu ◽  
Zhichao An ◽  
Jian Ni
Keyword(s):  
Literature Review ◽  
Kidney Diseases ◽  
Experimental Studies ◽  
Pharmacological Effects ◽  
Active Components ◽  
Pharmacological Activities ◽  
Cornus Officinalis ◽  
Liver And Kidney ◽  
Ancient Times ◽  
Anti Inflammation

Cornus officinalis Sieb. et Zucc. (Shanzhuyu), a herb and food plant in east Asia, has the properties of tonifying the liver and kidney, and nourishing the essence according to the theory of traditional Chinese medicine. C. officinalis has been commonly used to treat asthenia diseases, liver, and kidney diseases, and reproductive system diseases since ancient times. The objectives of this article were to review the pharmacological effects and phytochemistry of C. officinalis. We conducted a literature review of the pharmacological effects of C. officinalis by different systems and compared the effects with the traditional usages, discussed the research status and potential blanks to be filled. The experimental studies showed that C. officinalis extract and its active components had various pharmacological effects such as anti-oxidation, anti-apoptosis, anti-inflammation, anti-diabetes, anti-osteoporosis, immunoregulation, neuroprotection, and cardiovascular protection, but clinical studies are still needed to assess whether the reported pharmacological activities have confirmed efficacy.

scholarly journals Advances in Research on Chemical Constituents and Their Biological Activities of the Genus Actinidia

2021 ◽  
Author(s):  
Jin-Tao Ma ◽  
Da-Wei Li ◽  
Ji-Kai Liu ◽  
Juan He
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
Chemical Components ◽  
Research Development ◽  
Pharmacological Activities ◽  
The Past ◽  
Development And Utilization ◽  
Different Parts

AbstractKiwi, a fruit from plants of the genus Actinidia, is one of the famous fruits with thousand years of edible history. In the past twenty years, a great deal of research has been done on the chemical constituents of the Actinidia species. A large number of secondary metabolites including triterpenoids, flavonoids, phenols, etc. have been identified from differents parts of Actinidia plants, which exhibited significant in vitro and in vivo pharmacological activities including anticancer, anti-inflammatory, neuroprotective, anti-oxidative, anti-bacterial, and anti-diabetic activities. In order to fully understand the chemical components and biological activities of Actinidia plants, and to improve their further research, development and utilization, this review summarizes the compounds extracted from different parts of Actinidia plants since 1959 to 2020, classifies the types of constituents, reports on the pharmacological activities of relative compounds and medicinal potentials.

HPLC analysis and activity to determine the effect of drying and extraction on Ficus benghalensis leaves

2020 ◽  
Vol 9 (1) ◽  
pp. 6-10
Author(s):  
Nithyakalyani K
Keyword(s):  
Extraction Method ◽  
Chemical Constituents ◽  
Extraction Procedure ◽  
Chemical Constituent ◽  
Chemical Components ◽  
Drying Method ◽  
Ultrasound Assisted Extraction ◽  
Critical Stage ◽  
Ficus Benghalensis ◽  
Assisted Extraction

Ficus benghalensis is one of those taboo plants in India, which was claimed to be possessed and have weird effects on human health. Apart from this ficus species has a great variety of chemical constituents and an abundant amount of antioxidants. Drying is the most critical stage of improving the activity or preventing the loss of chemical components from a drug. There is another stage of ensuring high chemical constituent content in the plant and that is the extraction procedure. So the point of focus in the current research is to find the effect of extraction method and drying on the anti-inflammatory potential of the plant. The result of the extraction method and drying method of the plant was investigated and found that the ultrasound-assisted extraction of the shade dried leaves was found to give the highest yield of flavonoids and activity.

Sign in / Sign up

Export Citation Format

Share Document