scholarly journals Replacing Synthetic Ingredients by Sustainable Natural Alternatives: A Case Study Using Topical O/W Emulsions

Molecules ◽  
2020 ◽  
Vol 25 (21) ◽  
pp. 4887
Author(s):  
Sara Bom ◽  
Manuel Fitas ◽  
Ana Margarida Martins ◽  
Pedro Pinto ◽  
Helena Margarida Ribeiro ◽  
...  
Keyword(s):  
Research Study ◽  
Raw Materials ◽  
High Quality ◽  
Time Saving ◽  
Future Studies ◽  
Sustainable Products ◽  
Potential Applications ◽  
Physicochemical And Structural Properties

With the increasing debate on sustainability, there is a strong market trend to formulate more sustainable products for topical application. Several studies emphasize the potential applications of natural, organic, or green chemistry-derived ingredients, but comparative studies between conventional ingredients and sustainable alternatives are lacking. This type of study is considered an excellent baseline and time-saving strategy for future studies. In addition, one of the main challenges of replacing ingredients by sustainable alternatives in topical vehicles is to maintain high-quality products. Thus, the main goal of this research study was to create a well-defined strategy supported by specific experimental data for the development of sustainable topical vehicles with high-quality standards. The study was designed to evaluate the effects of replacing conventional ingredients (e.g., hydrocarbons, silicones, and preservatives) by sustainable ones on the physical, chemical, and microbiological features of topical emulsions. Additionally, in vivo assessment studies were performed to evaluate the safety, biological efficacy, and sensorial aspects of the developed formulations. The results obtained showed that the replacement of ingredients by sustainable alternatives has an effective impact on the physicochemical and structural properties of the emulsions, mainly on their rheological behavior. However, using appropriate strategies for ingredient selection and rheological adjustment, it is possible to overcome some barriers created by the use of natural raw materials, thus developing appealing and high-quality sustainable topical vehicles.

scholarly journals Detector-based component model abstraction for microservice-based systems

Computing ◽  
2021 ◽  
Author(s):  
Evangelos Ntentos ◽  
Uwe Zdun ◽  
Konstantinos Plakidas ◽  
Patric Genfer ◽  
Sebastian Geiger ◽  
...  
Keyword(s):  
Research Study ◽  
Software Systems ◽  
High Quality ◽  
Model Abstraction ◽  
Architecture Model ◽  
Continuous Evolution ◽  
Component Architecture ◽  
Stable Solutions ◽  
New Challenges

AbstractOne of the chief problems in software architecture is avoiding architecture model drift and erosion in all kinds of complex software systems. Microservice-based systems introduce new challenges in this context, as they often use a large variety of technologies in their latest iteration, and are changed and released very frequently. Existing solutions that can be used to reconstruct architecture models fall short in addressing these new challenges, as they cannot easily cope with continuous evolution, their accuracy is too low, and highly polyglot settings are not supported well. In this work, we report on a research study aiming to design a highly accurate architecture model abstraction approach for comprehending component architecture models of highly polyglot systems that can cope with continuous evolution. After analyzing the results of related studies, we found two possible architecture model abstraction approaches that meet the requirements of our study: an opportunistic, and a reusable semi-automatic detector-based approach. We have conducted an empirical case study for validation and comparison of the two approaches. We conclude that both detector approaches are feasible. In our case study, the reusable approach breaks even in terms of time and effort needed for establishing reuse, if modest reuse of detectors is possible, and is producing slightly more high quality and evolution-stable solutions than the opportunistic approach.

scholarly journals Rare Earth Elements Recovery Using Selective Membranes via Extraction and Rejection

Membranes ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 80
Author(s):  
Atiyeh Bashiri ◽  
Arash Nikzad ◽  
Reza Maleki ◽  
Mohsen Asadnia ◽  
Amir Razmjou
Keyword(s):  
Rare Earth ◽  
Rare Earth Elements ◽  
Active Sites ◽  
Membrane Separation ◽  
Raw Materials ◽  
Future Studies ◽  
Similar Chemical ◽  
Potential Applications ◽  
Environmentally Friendly Approach ◽  
Separation Of Rees

Recently, demands for raw materials like rare earth elements (REEs) have increased considerably due to their high potential applications in modern industry. Additionally, REEs’ similar chemical and physical properties caused their separation to be difficult. Numerous strategies for REEs separation such as precipitation, adsorption and solvent extraction have been applied. However, these strategies have various disadvantages such as low selectivity and purity of desired elements, high cost, vast consumption of chemicals and creation of many pollutions due to remaining large amounts of acidic and alkaline wastes. Membrane separation technology (MST), as an environmentally friendly approach, has recently attracted much attention for the extraction of REEs. The separation of REEs by membranes usually occurs through three mechanisms: (1) complexation of REE ions with extractant that is embedded in the membrane matrix, (2) adsorption of REE ions on the surface created-active sites on the membrane and (3) the rejection of REE ions or REEs complex with organic materials from the membrane. In this review, we investigated the effect of these mechanisms on the selectivity and efficiency of the membrane separation process. Finally, potential directions for future studies were recommended at the end of the review.

Authenticity perceptions in virtual environments

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Jamie N. Mikeska ◽  
Heather Howell
Keyword(s):  
Virtual Environments ◽  
Research Study ◽  
Teaching Practice ◽  
Teaching Experience ◽  
Virtual Classroom ◽  
Classroom Environments ◽  
Content Type ◽  
Future Studies ◽  
And Performance

Purpose This paper aims to examine three distinct aspects of authenticity that pre-service teachers (PSTs) experience when they engage with virtual classroom environments to develop their content-intensive instructional practice – task authenticity, student avatar authenticity and performance authenticity – and their perceptions about the usefulness of the simulated teaching experience to support their learning. Design/methodology/approach This paper explored these conceptions of authenticity and usefulness within a larger research study whose goal was to develop virtual environment tools to help elementary PSTs learn how to engage in one ambitious teaching practice: facilitating discussions that engage students in argumentation. To examine these aspects of authenticity and usefulness, this paper used a general qualitative deductive analysis approach to examine data from 104 interviews with 26 case study teachers and examined patterns in PSTs’ perceptions within and across interviews and authenticity aspects. Findings While these PSTs strongly value the utility of these tools to support their learning, findings point to variation in their perceptions of authenticity. Findings showed that most PSTs perceived the tasks as an authentic representation of the work of teaching. However, their perceptions of task authenticity did not always align with their perceptions of avatar or performance authenticity. Originality/value This paper argues that these three aspects of authenticity relate to, but expand upon, the broader notions of presence and plausibility noted in the literature on virtual environments and should be taken up more directly in future studies of users’ perceptions of virtual environments both within and outside of educational contexts.

Significance of In-Vitro and In-Vivo Correlation in Drug Delivery System

2018 ◽  
Vol 4 (4) ◽  
pp. 523-531
Author(s):  
Hina Mumtaz ◽  
Muhammad Asim Farooq ◽  
Zainab Batool ◽  
Anam Ahsan ◽  
Ashikujaman Syed
Keyword(s):  
Dosage Form ◽  
Pharmaceutical Preparations ◽  
Pharmacokinetic Profile ◽  
In Vitro Dissolution ◽  
Time Saving ◽  
Pharmaceutical Dosage Form ◽  
Short Period ◽  
Form Development

The main purpose of development pharmaceutical dosage form is to find out the in vivo and in vitro behavior of dosage form. This challenge is overcome by implementation of in-vivo and in-vitro correlation. Application of this technique is economical and time saving in dosage form development. It shortens the period of development dosage form as well as improves product quality. IVIVC reduce the experimental study on human because IVIVC involves the in vivo relevant media utilization in vitro specifications. The key goal of IVIVC is to serve as alternate for in vivo bioavailability studies and serve as justification for bio waivers. IVIVC follows the specifications and relevant quality control parameters that lead to improvement in pharmaceutical dosage form development in short period of time. Recently in-vivo in-vitro correlation (IVIVC) has found application to predict the pharmacokinetic behaviour of pharmaceutical preparations. It has emerged as a reliable tool to find the mode of absorption of several dosage forms. It is used to correlate the in-vitro dissolution with in vivo pharmacokinetic profile. IVIVC made use to predict the bioavailability of the drug of particular dosage form. IVIVC is satisfactory for the therapeutic release profile specifications of the formulation. IVIVC model has capability to predict plasma drug concentration from in vitro dissolution media.

TECHNOLOGICAL ASPECTS OF HIGH QUALITY RAW MATERIAL OBTAINING FOR PECTIN PRODUCTION

1970 ◽  
pp. 47-50
Author(s):  
I. A. Ilina ◽  
I. A. Machneva ◽  
E. S. Bakun
Keyword(s):  
Raw Materials ◽  
Thermal Characteristics ◽  
Environmental Safety ◽  
Raw Material ◽  
High Quality ◽  
Temperature Conductivity ◽  
Drying Temperature ◽  
Plant Raw Materials ◽  
Gel Forming Ability

  The article is devoted to the study of the chemical composition, physical and thermal-pfysical characteristics of damp apple pomaces and the identifying patterns of influence of drying temperature the functional composition and gel-forming ability of pectin. The research is aimed at obtaining initial data for the subsequent calculation of the main technological, hydro-mechanical, thermal, structural and economic characteristics of devices for drying the plant raw materials, ensuring the environmental safety and high quality of pectin-containing raw materials, the reducing heat and energy costs. As a result of the study of the thermal characteristics of apple pomaces, the critical points (temperature conductivity – 16.5 x 10-8 m2/s, thermal conductivity – 0.28 W/m K, heat capacity – 1627 j/(kg K)) at a humidity of 56 % are determined, which characterizing the transition from the extraction of weakly bound moisture to the extraction of moisture with strong bonds (colloidal, adsorption). It was found that the pomaces obtained from apples of late ripening have a higher content of solids (21-23 %), soluble pectin and protopectin (2.5-4.5 %). Dried pomaces obtained from apple varieties of late ripening contain up to 25 % pectin, which allow us to recommend them as a source of raw materials for the production of pectin. The optimum modes of preliminary washing of raw materials are offered, allowing to the remove the ballast substances as much as possible. It is established that when the drying temperature increases, the destructive processes are catalyzed: the strength of the pectin jelly and the uronide component and the degree of pectin esterification are reduced. The optimum drying temperature of damp apple pomaces is 80 0C, at which the quality of pectin extracted from the dried raw materials is maintained as much as possible. It is shown that the most effective for the pectin production is a fraction with a particle size of 3-5 mm, which allow us to extract up to 71 % of pectin from raw materials.

STRATEGI MENINGKATKAN LOYALITAS KONSUMEN MAKANAN KHAS KOTA CURUP KABUPATEN REJANG LEBONG

2019 ◽  
Author(s):  
Onsardi Onsardi
Keyword(s):  
Swot Analysis ◽  
Raw Materials ◽  
External Factors ◽  
Consumer Loyalty ◽  
Internal Factors ◽  
The Public ◽  
Typical Food ◽  
Internal And External Factors

The title of this study is the Strategy of Increasing Consumer Food Loyalty in CurupCity, Rejang Lebong Regency (Case Study in "Henvian" Typical Food Industry). Thisresearch is based on the importance of strategies in increasing business and consumerloyalty to products sold.Strategies to increase business and consumer loyalty can bedone with a SWOT analysis. Place of this research is the "Henvian" shop that sellstypical Rejang lebong food. The method used in this study is descriptive qualitative.Informants in this study were people who were considered to know for certain about theHENVIAN Specialty Food Store in Curup City, Rejang Lebong Regency. The dataanalysis technique used in this study is a SWOT analysis to determine the strengths,weaknesses, opportunities and threats in a typical Rejang Lebong food business.By using SWOT analysis techniques that consist of strengths (weakness), weaknesses(weakness), opportunities (opportnity) and threats (threath). The results of this studycan be concluded that the internal factors that are the strength of the marketing strategyare the quality of the product that is good at a price affordable to the public andtourists, service that is friendly and responsive to consumer needs, as well astechnological advancements that facilitate the promotion of business. Internal factorsthat are a weakness are often lack of stock, there are some products that do not meet thestandard packaging, the product shelf life is short, employees do not use uniforms.External factors that become opportunities are a fairly high economic community,abundant raw materials while external factors that are a threat are the manycompetitors, an unstable economy, the price of basic needs increases. Based on theresults of the SWOT analysis of internal and external factors, the strategy used is toimprove product quality by improving the appearance of packaging and quality ofcontent and quality of service by providing uniforms to employees and providingstandards of service to consumers. .Keywords: Strategy, Consumer Loyalty, SWOT

scholarly journals Using the Google™ Search Engine for Health Information: Is There a Problem? Case Study: Supplements for Cancer

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Hannah C Cai ◽  
Leanne E King ◽  
Johanna T Dwyer
Keyword(s):  
Health Information ◽  
Search Engine ◽  
Information Quality ◽  
Nutrition Information ◽  
High Quality ◽  
Search Results ◽  
Health And Nutrition ◽  
Quality Rating

ABSTRACT We assessed the quality of online health and nutrition information using a Google™ search on “supplements for cancer”. Search results were scored using the Health Information Quality Index (HIQI), a quality-rating tool consisting of 12 objective criteria related to website domain, lack of commercial aspects, and authoritative nature of the health and nutrition information provided. Possible scores ranged from 0 (lowest) to 12 (“perfect” or highest quality). After eliminating irrelevant results, the remaining 160 search results had median and mean scores of 8. One-quarter of the results were of high quality (score of 10–12). There was no correlation between high-quality scores and early appearance in the sequence of search results, where results are presumably more visible. Also, 496 advertisements, over twice the number of search results, appeared. We conclude that the Google™ search engine may have shortcomings when used to obtain information on dietary supplements and cancer.

scholarly journals ArcGIS Urban: an application for plan assessment

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Ellen Soward ◽  
Jianling Li
Keyword(s):  
United States ◽  
The United States ◽  
Spatial Context ◽  
Future Studies ◽  
Planning Profession ◽  
Gis Tools ◽  
Comprehensive Plans ◽  
Near Future ◽  
The City

AbstractMost cities in the United States rely on zoning to address important planning-related issues within their jurisdictions. Planners often use GIS tools to analyze these issues in a spatial context. ESRI’s ArcGIS Urban software seeks to provide the planning profession with a GIS-based solution for various challenges, including zoning’s impacts on the built environment and housing capacity.This research explores the use of ArcGIS Urban for assessing the existing zoning and comprehensive plans in meeting the projected residential growth in the near future using the City of Arlington, Texas as a case study. The exploration provides examples and lessons for how ArcGIS Urban might be used by planners to accomplish their tasks and highlights the capabilities and limitations of ArcGIS Urban in its current stand. The paper is concluded with some suggestions for future studies.

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