scholarly journals Salvia officinalis L. from Italy: A Comparative Chemical and Biological Study of Its Essential Oil in the Mediterranean Context

Molecules ◽  
2020 ◽  
Vol 25 (24) ◽  
pp. 5826
Author(s):  
Rosa Tundis ◽  
Mariarosaria Leporini ◽  
Marco Bonesi ◽  
Simone Rovito ◽  
Nicodemo G. Passalacqua
Keyword(s):  
Gas Chromatography ◽  
Essential Oil ◽  
Antioxidant Properties ◽  
Salvia Officinalis ◽  
Biologically Active ◽  
In Vitro Assays ◽  
Biological Study ◽  
Reducing Ability ◽  
The Mediterranean ◽  
Salvia Officinalis L

Salvia officinalis L. (sage) is one of the most appreciated plants for its plethora of biologically active compounds. The objective of our research was a comparative study, in the Mediterranean context, of chemical composition, anticholinesterases, and antioxidant properties of essential oils (EOs) from sage collected in three areas (S1–S3) of Southern Italy. EOs were extracted by hydrodistillation and analyzed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory properties were investigated by employing Ellman’s method. Four in vitro assays, namely, 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), ferric-reducing ability power (FRAP), and β-carotene bleaching tests, were used to study the antioxidant effects. Camphor (16.16–18.92%), 1,8-cineole (8.80–9.86%), β-pinene (3.08–9.14%), camphene (6.27–8.08%), and α-thujone (1.17–9.26%) are identified as the most abundant constituents. However, the content of these constituents varied depending on environmental factors and pedoclimatic conditions. Principal component analysis (PCA) was performed. Based on Relative Antioxidant Capacity Index (RACI), S2 essential oil exhibited the highest radical potential with an IC50 value of 20.64 μg/mL in ABTS test and presented the highest protection of lipid peroxidation with IC50 values of 38.06 and 46.32 μg/mL after 30 and 60 min of incubation, respectively. The most promising inhibitory activity against BChE was found for S3 sample (IC50 of 33.13 μg/mL).

scholarly journals COMPARATIVE STUDY OF ANTIOXIDANT ACTIVITY, PHENOLIC COMPOUNDS AND FLAVONOIDS OF LINDEN-SHAPED FLOWERS OF THE HEART (TILIA CORDATA MILL.), MEDICINAL SAGE (SALVIA OFFICINALIS L.), MEDICINAL SWEET CLOVER (MELILOTUS OFFICINALIS L.), CURRANT LEAVES (RIBES NIGR

2019 ◽  
pp. 153-159 ◽  
Author(s):  
Sof'ya Anatol'yevna Aleksashina ◽  
Nadezhda Viktorovna Makarova
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Properties ◽  
Salvia Officinalis ◽  
Biologically Active ◽  
Tilia Cordata ◽  
Restoring Force ◽  
Antioxidant Power ◽  
Melilotus Officinalis ◽  
Wild Strawberry ◽  
Salvia Officinalis L

A reliable source of increased intake of vitamins and biologically active substances are not only berries and fruits, but also herbs. This article is devoted to the analysis of plant samples for antioxidant activity. The objects of study were selected herbs and flowering woody plants of the Samara region: small-leaved linden color (Tilia cordata), medicinal sage (Salvia officinalis L.), medicinal clover (Melilоtus officinalis), currant leaf (Folium Ribes nigrum), wild strawberry (Fragum folium silvam), grapes (Vitis labrusca). Plant material collected in the phase of mass flowering. Aqueous alcoholic extracts (1 : 1 ratio) were obtained from the samples at 37 °C for 2 hours. Anti-radical activity was tested using the free radical DPPH (2,2-diphenyl-1-pilkrilgidrazil), restoring force the FRAP method (Ferric Reduction Antioxidant Power), antioxidant activity in the linoleic acid system and the content of phenols, flavonoids. Analyzing the results obtained in this work, we can conclude about the presence of antioxidant properties. The leader in anti-radical activity and regenerative power was a currant leaf, a high content of phenols has linden color, the maximum content of flavonoids was also recorded in a currant leaf.

Contribution to the Optimization of a Gas Chromatographic Method by QbD Approach used for Analysis of Essential Oils from Salvia officinalis

2019 ◽  
Vol 70 (6) ◽  
pp. 2015-2020
Author(s):  
Silvia Robu ◽  
Aurelia Romila ◽  
Olimpia Dumitriu Buzia ◽  
Adrian Florin Spac ◽  
Camelia Diaconu ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Plant Material ◽  
Mobile Phase ◽  
Chromatographic Method ◽  
Salvia Officinalis ◽  
Salvia Officinalis L ◽  
Gas Chromatographic Method

Numerous articles on Salvia officinalis L. have been published regarding the composition of their essential oil. The considerable variation found may be due to the quality of the plant material as well as to the methods used for analysis. A simple GC-MS method was developed and optimized in the QbD approach, for the determination of sage essential oils. The optimization of GC-MS analysis was performed using different mobile phase flows, injection volumes, split ratios and temperature programs. The optimized method proved to be simple and can be successfully applied for the determination of sage essential oils.

Identification and Determination of the Components of Garden Sage (Salvia officinalis L.) Essential Oil, Isolated by Different Extraction Methods

2020 ◽  
Vol 75 (11) ◽  
pp. 1451-1460
Author(s):  
Z. A. Temerdashev ◽  
V. V. Milevskaya ◽  
L. P. Ryabokon’ ◽  
N. N. Latin ◽  
N. V. Kiseleva ◽  
...  
Keyword(s):  
Essential Oil ◽  
Extraction Methods ◽  
Salvia Officinalis ◽  
Salvia Officinalis L

Behavior of Listeria monocytogenes in beef Sous vide cooking with Salvia officinalis L. essential oil, during storage at different temperatures

LWT ◽  
2020 ◽  
Vol 132 ◽  
pp. 109896
Author(s):  
Márcio Moura-Alves ◽  
Ana R. Gouveia ◽  
José M.M. M. de Almeida ◽  
Filipe Monteiro-Silva ◽  
José A. Silva ◽  
...  
Keyword(s):  
Listeria Monocytogenes ◽  
Essential Oil ◽  
Salvia Officinalis ◽  
Different Temperatures ◽  
Sous Vide ◽  
Salvia Officinalis L

scholarly journals Premna odorata: Seasonal Metabolic Variation in the Essential Oil Composition of Its Leaf and Verification of Its Anti-Ageing Potential via In Vitro Assays and Molecular Modelling

Biomolecules ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 879
Author(s):  
Ahmed E. Altyar ◽  
Mohamed L. Ashour ◽  
Fadia S. Youssef
Keyword(s):  
Gas Chromatography ◽  
Essential Oil ◽  
Molecular Modelling ◽  
Essential Oil Composition ◽  
In Vitro Assays ◽  
Oil Composition ◽  
Different Seasons ◽  
Metabolic Variation ◽  
Active Centres

The metabolic variation in the essential oil composition of Premna odorata leaves obtained from different seasons was quantitatively and qualitatively determined employing GC/MS (Gas Chromatography coupled with Mass Spectrometry) and GC/FID (Gas chromatography equipped with flame ionization detector) techniques. It displayed the existence of 97 constituents accounting for 94.19%, 92.27%, 91.95% and 92.63% for POS (spring), POM (summer), POA (autumn) and POW (winter) whole essential oils. β-Caryophyllene constituting the main metabolite in the oil in the different seasons. To better visualize the differences between them, GC data were exposed to chemometric analysis. A PCA (principal component analysis) score plot revealed the closeness of POS and POW. Molecular modelling on collagenase, elastase and hyaluronidase enzymes active centres shows that different compounds existing in the essential oil of Premna odorata leaves shows binding to the active sites with variable degrees that suggested its anti-ageing potential. Palmitic acid displayed the highest fitting for both the collagenase and elastase active centres in both pH-based and rule-based ionization methods with ∆G equals −78.27 and −44.77 kcal/mol, respectively; meanwhile, heptacosane showed the highest fitting score in the hyaluronidase centre with ∆G = −43.78 kcal/mol. In vitro assays consolidates the obtained modelling studies in which essential oil shows considerable anti-elastase and anti-hyaluronidase potential as evidenced by their IC50 values being 49.3 and 37.7 μg/mL, respectively; meanwhile, the essential oil of Premna odorata leaves displayed mild anti-collagenase potential. Thus, it can be concluded that Premna odorata could serve as a promising anti-ageing naturally occurring drug that could be effectively incorporated by pharmaceutical industries in cosmetics combating ageing and skin wrinkling.

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