scholarly journals Chrononutrition and Polyphenols: Roles and Diseases

Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2602 ◽  
Author(s):  
Anna Arola-Arnal ◽  
Álvaro Cruz-Carrión ◽  
Cristina Torres-Fuentes ◽  
Javier Ávila-Román ◽  
Gerard Aragonès ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Fruits And Vegetables ◽  
Chemical Cues ◽  
Biological Rhythms ◽  
Research Field ◽  
Dietary Recommendations ◽  
Phenolic Profile ◽  
Phenolic Profiles ◽  
The Impact

Biological rhythms can influence the activity of bioactive compounds, and at the same time, the intake of these compounds can modulate biological rhythms. In this context, chrononutrition has appeared as a research field centered on the study of the interactions among biological rhythms, nutrition, and metabolism. This review summarizes the role of phenolic compounds in the modulation of biological rhythms, focusing on their effects in the treatment or prevention of chronic diseases. Heterotrophs are able to sense chemical cues mediated by phytochemicals such as phenolic compounds, promoting their adaptation to environmental conditions. This is called xenohormesis. Hence, the consumption of fruits and vegetables rich in phenolic compounds exerts several health benefits, mainly attributed to the product of their metabolism. However, the profile of phenolic compounds present in plants differs among species and is highly variable depending on agricultural and technological factors. In this sense, the seasonal consumption of polyphenol-rich fruits could induce important changes in the regulation of physiology and metabolism due to the particular phenolic profile that the fruits contain. This fact highlights the need for studies that evaluate the impact of these specific phenolic profiles on health to establish more accurate dietary recommendations.

Lutein as an Ingredient in Pediatric Nutritionals

2019 ◽  
Vol 102 (4) ◽  
pp. 1034-1043
Author(s):  
Amy C Long ◽  
Matthew Kuchan ◽  
Amy D Mackey
Keyword(s):  
Fruits And Vegetables ◽  
Critical Time ◽  
Physiological Role ◽  
Dietary Recommendations ◽  
Neural Tissues ◽  
Blue Wavelength ◽  
The Impact ◽  
Wavelength Light

Abstract Lutein is a xanthophyll carotenoid that can be found in a variety of fruits and vegetables that may be limiting in the pediatric diet, which makes it an attractive nutrient for addition to supplemental nutritional products. Including lutein in the diet from a young age may provide protective benefits during a critical time of ocular and cognitive development. Lutein accumulation in eye and brain has led to research to better define the physiological role of this nutrient. Infants are exposed to lutein primarily through the consumption of breast milk or infant formulas containing lutein. The ingredient has been evaluated to be safe by many scientific and regulatory authorities for the addition to food, including formulated nutritional products. Nonhuman primates have been important in the investigation of the role dietary lutein in eye and brain function. Studies examining diets low or absent in lutein have revealed the impact on brain and eye function. Diets low in lutein may compromise neural tissues such as those found in the eye, which are susceptible to oxidation from blue wavelength light. No dietary recommendations have been established for lutein; however, several publications have highlighted the accumulating evidence that lutein provides long-term benefits when incorporated in adequate amounts in the diet.

scholarly journals Differences in the Phenolic Profile by UPLC Coupled to High Resolution Mass Spectrometry and Antioxidant Capacity of Two Diospyros kaki Varieties

Antioxidants ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 31
Author(s):  
Adelaida Esteban-Muñoz ◽  
Silvia Sánchez-Hernández ◽  
Cristina Samaniego-Sánchez ◽  
Rafael Giménez-Martínez ◽  
Manuel Olalla-Herrera
Keyword(s):  
Phenolic Compounds ◽  
Antioxidant Capacity ◽  
Fruits And Vegetables ◽  
High Resolution Mass Spectrometry ◽  
Extraction Procedure ◽  
Chemical Species ◽  
Diospyros Kaki ◽  
Phenolic Profile ◽  
Matrix Interferences ◽  
Individual Health

Background: phenolic compounds are bioactive chemical species derived from fruits and vegetables, with a plethora of healthy properties. In recent years, there has been a growing interest in persimmon (Diospyros kaki L.f.) due to the presence of many different classes of phenolic compounds. However, the analysis of individual phenolic compounds is difficult due to matrix interferences. Methods: the aim of this research was the evaluation of individual phenolic compounds and antioxidant capacity of the pulp of two varieties of persimmon (Rojo Brillante and Triumph) by an improved extraction procedure together with a UPLC-Q-TOF-MS platform. Results: the phenolic compounds composition of persimmon was characterized by the presence of hydroxybenzoic and hydroxycinnamic acids, hydroxybenzaldehydes, dihydrochalcones, tyrosols, flavanols, flavanones, and flavonols. A total of 31 compounds were identified and 17 compounds were quantified. Gallic acid was the predominant phenolic compounds found in the Rojo Brillante variety (0.953 mg/100 g) whereas the concentration of p-hydroxybenzoic acid was higher in the Triumph option (0.119 mg/100 g). Conclusions: the results showed that the Rojo Brillante variety had higher quantities of phenolic compounds than the Triumph example. These data could be used as reference in future phenolic compound databases when individual health effects of phenolic compounds become available.

scholarly journals ПЕРСПЕКТИВИ ЗАСТОСУВАННЯ ЧУБУШНИКА ЯК ЛІКАРСЬКОЇ РОСЛИНИ

2016 ◽  
Vol 18 (3(70)) ◽  
pp. 123-128
Author(s):  
V.D. Ishchenko ◽  
S.V. Kostenko ◽  
V.M. Kostenko ◽  
Y.V. Tymoshyk
Keyword(s):  
Veterinary Medicine ◽  
Phenolic Compounds ◽  
Metabolic Regulation ◽  
Reagent Solution ◽  
High Concentration ◽  
Natural Origin ◽  
Basic Action ◽  
Veterinary Practice ◽  
The Impact

Medicinal plants are insufficiently studied and almost endless. The use of phytomedication enables reduce the impact of xenobiotics on animals organism through the natural origin of active compounds and associated and auxiliary substances smoothing the basic action and prevent the manifestation of side effects. One of such plants the possibility of using in veterinary practice is still insufficiently studied is mock–orange. Considering on the important role of phenolic compounds in the metabolic regulation of plant and diversity of impact of these substances on organism of animals and humans, in leaves of mock–oranges different cultivar was identified the content of phenolic secondary metabolites to identify the prospects for their further using in veterinary medicine. The qualitative reaction with the Wilson reagent, solution of iron (III) chloride and by cyanidin reaction in extracts from mock–orange leaves was established the presence of phenolic compounds. Further phytochemical investigations established that the content of phenols in the investigated extracts is between 33.0 ± 0.48 to 107.1 ± 0.91 mg/g (in Philadelphus L. 'Avalanche'). The content of flavonoids in alcohol extracts from leaves of different species of mock–oranges varies from 5.3 ± 0.41 to 10.6 ± 0.41 mg/g. Greatest quantity of flavonoids at relatively of low content of phenols contained in the preparation from leaves of Philadelphus coronaries 'Nana '(mock–orange dwarf), the use of which, along with Philadelphus L. 'Avalanche' can be perspective in medical and veterinary practice, considering on the high concentration of phenols and flavonoids and coumarins in these mock–oranges breed.  

scholarly journals The Role of Histone Acetylation and the Microbiome in Phytochemical Efficacy for Cardiovascular Diseases

2020 ◽  
Vol 21 (11) ◽  
pp. 4006
Author(s):  
Levi W. Evans ◽  
Maheshi Athukorala ◽  
Kristina Martinez-Guryn ◽  
Bradley S. Ferguson
Keyword(s):  
Cardiovascular Diseases ◽  
Histone Acetylation ◽  
Fruits And Vegetables ◽  
Financial Burden ◽  
Epigallocatechin Gallate ◽  
Mechanisms Of Action ◽  
Global Changes ◽  
Treatment And Prevention ◽  
The Impact

Cardiovascular diseases (CVD) are the main cause of death worldwide and create a substantial financial burden. Emerging studies have begun to focus on epigenetic targets and re-establishing healthy gut microbes as therapeutic options for the treatment and prevention of CVD. Phytochemicals, commonly found in fruits and vegetables, have been shown to exert a protective effect against CVD, though their mechanisms of action remain incompletely understood. Of interest, phytochemicals such as curcumin, resveratrol and epigallocatechin gallate (EGCG) have been shown to regulate both histone acetylation and microbiome re-composition. The purpose of this review is to highlight the microbiome–epigenome axis as a therapeutic target for food bioactives in the prevention and/or treatment of CVD. Specifically, we will discuss studies that highlight how the three phytochemicals above alter histone acetylation leading to global changes in gene expression and CVD protection. Then, we will expand upon these phytochemicals to discuss the impact of phytochemical–microbiome–histone acetylation interaction in CVD.

scholarly journals The Impact of Employee Engagement on Job Insecurity by Moderating Role of Psychological Empowerment to Enhance Corporate Performance

2019 ◽  
Vol 10 (4) ◽  
pp. 72-88
Author(s):  
Mubshara Hassan Ramey ◽  
Muhammad Jawad ◽  
Munazza Naz ◽  
Ayşe Küçük Yılmaz ◽  
Ebru Yazgan
Keyword(s):  
Employee Engagement ◽  
Survey Methodology ◽  
Oil And Gas ◽  
Psychological Empowerment ◽  
Job Insecurity ◽  
Pearson Correlation ◽  
Research Field ◽  
The Impact ◽  
Moderating Role

Human resources have had a strategic role in both sustainable and competitive business since it is inimitable element of business. The purpose of this research is to investigation the impact of employee engagement (independent variable) on job insecurity (dependent variable) and then moderating role of psychological empowerment of employees in oil and gas sector. These variables have the key significance for their employees and betterment of the organizations. It is a qualitative research, field study through survey methodology, 100 employees of 11 multinational oil and gas companies participated in the study from Pakistan. Cronbach alpha, Pearson correlation coefficient and hierarchal regression were used for various analyzes of this study. The findings of the research revealed that employee engagement is significant for reducing feelings of insecurity in a job, meanwhile if they are empowered psychologically, their commitment and loyalty is increased many times. Findings of this study will provide the insight to the benefits, challenges and issues related with it.

scholarly journals Toxicological aspects of the use of phenolic compounds in disease prevention

2011 ◽  
Vol 4 (4) ◽  
pp. 173-183 ◽  
Author(s):  
Zuzana Kyselova
Keyword(s):  
Phenolic Compounds ◽  
Disease Prevention ◽  
Dietary Supplements ◽  
Fruits And Vegetables ◽  
Research Field ◽  
Cytotoxic Effects ◽  
Traditional Medicines ◽  
Natural Substances ◽  
Lifestyle Diseases ◽  
Plant Sources

Toxicological aspects of the use of phenolic compounds in disease preventionThe consumption of a diet low in fat and enhanced by fruits and vegetables, especially rich in phenolic compounds, may reduce risks of many civilization diseases. The use of traditional medicines, mainly derived from plant sources, has become an attractive segment in the management of many lifestyle diseases. Concerning the application of dietary supplements (based on phenolic compounds) in common practice, the ongoing debate over possible adverse effects of certain nutrients and dosage levels is of great importance. Since dietary supplements are not classified as drugs, their potential toxicities and interactions have not been thoroughly evaluated. First, this review will introduce phenolic compounds as natural substances beneficial for human health. Second, the potential dual mode of action of flavonoids will be outlined. Third, potential deleterious impacts of phenolic compounds utilization will be discussed: pro-oxidant and estrogenic activities, cancerogenic potential, cytotoxic effects, apoptosis induction and flavonoid-drug interaction. Finally, future trends within the research field will be indicated.

PERAN LEMBAGA KEUANGAN MIKRO BAITUL MAAL WAT TAMWIL (BMT) TERHADAP PENGEMBANGAN USAHA PEDAGANG

2020 ◽  
Vol 2 (2) ◽  
pp. 12
Author(s):  
Nur Aidil ◽  
M. Thahir Maloko ◽  
A. Intan Cahyani
Keyword(s):  
Data Management ◽  
Field Research ◽  
Research Field ◽  
Microfinance Institutions ◽  
Validity Testing ◽  
Microfinance Institution ◽  
Data Validity ◽  
Management Techniques ◽  
The Impact

AbstrakPenelitian ini membahas peran lembaga keungan mikro baitul maal wa tamwil (BMT) terhadap pengembangan usaha pedagang, dan dampak yang ditimbulkan oleh lembaga keuangan BMT dalam pengembangan usaha pedagang.Jenis penelitian ini adalah penelitian lapangan (field research) menggunakan metode kualitatif dimana dilakukan dengan pendekatan teologis normatif, sosiologis dan fenomenologi dengan sumber data dari  BMT fastabiqul Khorat, selanjutnya metode pengumpulan data yang dilakukan adalah observasi, wawancara, dokumentasi, kemudian tekhnik pengelolaan data dilakukan melalui beberapa tahapan diantaranya: reduksi data, melakukan pengelolaan data dan pengujian keabsahan data. Hasil penelitian tersebut menunjukkan bahwa Baitul maal wat tamwil Fastabiqul Khoirat (BMT) sebagai lembaga keuangan mikro mempunyai peran mengurangi praktek riba, serta mensejahterahkan masyarakat kecil. Sedangkan dampak  yang diberikan BMT terhadap pengembangan usaha pedagang yakni BMT memberikan kontribusi dalam pengembangan usaha pedagang karena BMT melakukan pembiayaan kepada pedagang sehingga dapat mendorong pertumbuhan ekonomi pedagang.Kata Kunci : Baitul Mal Wa Tanwil, Pedagang, Pembiayaan Mikro. AbstractThis thesis discusses the role of microfinance institutions baitul maal wa tamwil (BMT) in the development of merchant businesses, and the impact caused by BMT financial institutions in the development of merchant businesses. This type of research is field research (field research) using qualitative methods which is carried out with a theological approach. normative, sociological and phenomenological with data sources from BMT fastabiqul Khorat, then the data collection methods used are observation, interviews, documentation, then data management techniques are carried out through several stages including: data reduction, data management and data validity testing. The results of this study indicate that Baitul maal wat tamwil Fastabiqul Khoirat (BMT) as a microfinance institution has a role in reducing the practice of usury, and in prospering the poor. Meanwhile, the impact given by BMT on the development of merchant business, namely BMT contributes to the development of merchant business because BMT provides financing to traders so that it can encourage economic growth of traders.Keywords: Baitul Mal Wa Tanwil, Micro Financing, Trader.

Recommended Consumption of Fruits and Vegetables Increases the Intake of Polyphenols and Flavonoids in Brazilian Adults

2020 ◽  
Vol 16 (3) ◽  
pp. 314-322
Author(s):  
Gelvani Locateli ◽  
Rosane Marina Peralta ◽  
Eloá Angélica Koehnlein
Keyword(s):  
Phenolic Compounds ◽  
Fruits And Vegetables ◽  
Bioactive Compound ◽  
World Health ◽  
High Consumption ◽  
The World ◽  
Polyphenol Intake ◽  
Health Organization ◽  
The Impact ◽  
Average Consumption

Background: Adequate consumption of fruits and vegetables (FV) is associated with reduced risks of various diseases, especially due to their nutrient, fiber, and bioactive compound content. Polyphenols are included in this last class. In Brazil, as in several other regions of the world, consumption of FV is low. Data on the importance of the recommended intake of FV for the ingestion of these compounds and subclasses are scarce. Objective: To estimate the intake of polyphenols by Brazilian adults and to verify the impact of the recommended consumption of FV for this intake. Methods: Data from 21,959 adults were obtained from the Brazilian Dairy Survey of the Household Budget Survey (POF 2008-2009). Food intake was estimated from a single food register. Polyphenol intake was calculated using the Phenol-Explorer database. To evaluate the impact of FV on the consumption of polyphenols, the population was divided into two groups according to the FV intake as recommended by the World Health Organization. Results: The average consumption of phenolic compounds was 441.04 mg among individuals consuming less than 400 g of FV daily, and 651.86 mg those consuming equal or more than 400 g daily. In addition, individuals consuming 400 g or more FV per day consumed approximately 12 times more phenolic from FV, especially flavonoids and the anthocyanin and flavanone subclasses. Conclusions: The high consumption of FV is essential for a higher dietary intake and diversity of polyphenols and flavonoids compounds by the Brazilian population.

scholarly journals State-Owned Shareholding and CSR: Do Multiple Financing Methods Matter?—Evidence from China

2019 ◽  
Vol 11 (5) ◽  
pp. 1292 ◽  
Author(s):  
Mingyuan Guo ◽  
Yanfang Hu ◽  
Yu Zhang ◽  
Fuge Tian
Keyword(s):  
Social Responsibility ◽  
Positive Impact ◽  
Research Field ◽  
Robust Test ◽  
Cross Listing ◽  
Cross Terms ◽  
Corporate Social ◽  
The Impact ◽  
Positive Effect

Corporate Social Responsibility (CSR) gradually deepens its influence on enterprises and rapidly becomes one of the important issues in the research field. This paper selects China’s A-share listed companies which issued social responsibility reports from 2011 to 2015, and studies the impact of state-owned shares on the disclosure level of CSR. Furthermore, this paper uses cross terms to study the role of different financing methods (issuing bonds and cross-listing) in the impact of state-owned shares on the disclosure level of CSR. The results show that state-owned shares and the proportion of state-owned shares have a significant positive impact on the disclosure level of CSR. Both the issuing of bonds and cross-listing can promote this positive effect. The results of robust test also support this conclusion. Finally, specific recommendations are put forward.

scholarly journals Digestive Stability and Bioaccessibility of Antioxidants in Prickly Pear Fruits from the Canary Islands: Healthy Foods and Ingredients

Antioxidants ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. 164 ◽  
Author(s):  
Andrea Gómez-Maqueo ◽  
Marilena Antunes-Ricardo ◽  
Jorge Welti-Chanes ◽  
M. Pilar Cano
Keyword(s):  
Phenolic Compounds ◽  
Canary Islands ◽  
Prickly Pear ◽  
Healthy Foods ◽  
Food Matrix ◽  
Potential Health ◽  
Phenolic Profile ◽  
Phenolic Profiles ◽  
By Products

Although prickly pear fruits have become an important part of the Canary diet, their native varieties are yet to be characterized in terms of betalains and phenolic compounds. To exert potential health benefits, these antioxidants must be released from the food matrix and be stable in the gastrointestinal tract. Our aim was to characterize the betalain and phenolic profile of four prickly pear varieties from the Canary Islands (Spain) and determine their digestive stability and bioaccessibility via in vitro gastrointestinal digestion. Digestive studies were performed considering the (i) importance of the edible fraction (pulps) and (ii) potential of fruit peels as by-products to obtain healthy ingredients. Betalains and phenolic profiles were analyzed by HPLC-DAD-ESI/MS and HPLC-DAD-MS/QTOF. Pulps in Colorada and Fresa varieties presented high indicaxanthin and betanin content, respectively. Despite low pH in the gastric phase, betalains were stable to reach the intestinal phase, although indicaxanthin presented a higher bioaccessibility. Blanco Buenavista peels contained a distinct flavonoid profile including a new isorhamnetin-hexosyl-rhamnoside. Phenolic compounds were abundant and highly bioaccessible in fruit peels. These findings suggest that prickly pear pulps are rich in bioaccessible betalains; and that their peels could be proposed as potential by-products to obtain sustainable healthy ingredients.

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