Association of the Dietary Approaches to Stop Hypertension, Physical Activity, and Their Combination with Semen Quality: A Cross-Sectional Study

The influence of individual lifestyle factors is widely described in studies on semen quality. However, their synergistic effect is often neglected. The aim of the study was to examine the association between semen quality and dietary approaches to stop hypertension (DASH) diet, physical activity (PA), and the two separately and in combination. A cross-sectional study was carried out among 207 men aged 20–55. Dietary data were collected by a food frequency questionnaire (FFQ) and analysed according to the DASH scoring index. Physical activity was evaluated by the International Physical Activity Questionnaire. Semen parameters were assessed via the computer-aided semen analysis (CASA). Adherence to the DASH diet was associated with higher sperm count (ΔT3-T1 = 82.1 mln/ej) and concentration (ΔT3-T1 = 24.6 mln/mL). Higher PA was related to higher sperm count (ΔT3-T1 = 69.4 mln/ej), total (ΔT3-T1 = 11.9%), and progressive motility (ΔT3-T1 = 8.5%) and morphology (ΔT3-T1 = 2.8%) in the crude model and remained significant after adjustment. The combination of the DASH diet and PA, was significantly positively associated with sperm count (ΔT3-T1 = 98.1 mln/ej), sperm concentration (ΔT3-T1 = 17.5 mln/mL), total (ΔT3-T1 = 11.8%), and progressive motility (ΔT3-T1 = 10.0%) and morphology (ΔT3-T1 = 3.3%) in both models. Adherence to the DASH diet was related to higher sperm count and concentration, whereas after its combination with physical activity it was also positively correlated with sperm motility and morphology.

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Semen quality pattern and age threshold: a retrospective cross-sectional study of 71,623 infertile men in China, between 2011 and 2017

Reproductive Biology and Endocrinology ◽

10.1186/s12958-019-0551-2 ◽

2019 ◽

Vol 17 (1) ◽

Cited By ~ 1

Author(s):

W. N. Li ◽

M. M. Jia ◽

Y. Q. Peng ◽

R. Ding ◽

L. Q. Fan ◽

...

Keyword(s):

Semen Quality ◽

Sperm Count ◽

Sperm Concentration ◽

Cross Sectional Study ◽

Semen Parameters ◽

Sectional Study ◽

Joinpoint Regression ◽

Cross Sectional ◽

Progressive Motility ◽

Infertile Men

Abstract Background The aim of this study was to provide information on the semen quality pattern of infertile men and age thresholds for semen parameters in China. Methods This was a retrospective cross-sectional study investigating 71,623 infertile men from the Reproductive and Genetic Hospital of CITIC Xiangya in Hunan, China, from 2011 to 2017. The Kruskal-Wallis test, Mann-Kendall test, linear regression model and joinpoint regression were used. Results Although erratic changes were observed in the median semen parameters (sperm concentration 40.1–52.1 × 106/ml, total sperm count 117.8–153.1 × 106, sperm progressive motility 33.4–38.1%) during the 7 years of observation, no significant decrease in semen quality was found, and 47.88% of infertile men showed normal semen parameters according to the World Health Organization (WHO) criteria. According to the joinpoint regression analysis, sperm progressive motility appeared to decrease earlier than the sperm concentration and total sperm count (at 28, 58, and 42 years of age, respectively). Conclusions There is no evidence of a deterioration in semen quality among infertile men in Hunan, China. Semen parameters decreased with increasing age, with turning points noted at different ages. Semen parameters are not absolute evidence for the assessment of male fertility potential. Therefore, we believe that, among semen parameters, the sperm concentration is the best predictor of fertility for ART, followed by motility. Decreased sperm motility may affect natural pregnancy, but it is not necessary for successful IVF.

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Dietary Patterns and Poor Semen Quality Risk in Men: A Cross-Sectional Study

Nutrients ◽

10.3390/nu10091162 ◽

2018 ◽

Vol 10 (9) ◽

pp. 1162 ◽

Cited By ~ 8

Author(s):

Anna Danielewicz ◽

Katarzyna Przybyłowicz ◽

Mariusz Przybyłowicz

Keyword(s):

Dietary Patterns ◽

Semen Quality ◽

Sperm Quality ◽

Cross Sectional Study ◽

Quality Parameters ◽

Semen Parameters ◽

Sectional Study ◽

Cross Sectional ◽

Progressive Motility ◽

Increased Risk

The etiology of diminished sperm quality in about 30% of male infertility cases generally remains unexplained. Some studies have suggested that specific nutritional factors can affect semen quality. The aim of this study was to evaluate an association between dietary patterns (DPs) and the risk of abnormal semen quality parameters in men. This cross-sectional study was carried out in 114 men aged 20–55 years from Poland. Semen parameters were assessed via computer-aided semen. Diet was assessed by a food frequency questionnaire (FFQ). DPs were derived using Principal Component Analysis (PCA). Two DPs were derived: Pro-healthy and Western. After adjusting for potential confounders, the risk of abnormal progressive motility was significantly higher in the middle (OR: 2.89, 95% CI: 1.03–8.09) and upper (OR: 7.78, 95% CI: 1.52–15.06) tertiles of the Western DP. A trend for increased risk of the abnormal total count, progressive motility, and morphology (P-trend < 0.050) was found in Western DP. To conclude, the Western DP may increase the risk of abnormal semen parameters, whereas no association was found in the case of Pro-healthy DP. These findings stand in contrast to an increasing number of research findings indicating a positive relation between intake of healthy foods or diet and semen quality parameters. The results highlight the need to study whether modifications in diet and lifestyle factors improve semen quality.

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Built Environment and Semen Quality in Korean Men with a History of Infertility: A Cross-Sectional Study

10.21203/rs.3.rs-93400/v1 ◽

2020 ◽

Author(s):

Seung-Ah Choe ◽

Seulgi Kim ◽

Changmin Im ◽

Sun-Young Kim ◽

Gregory Wellenius ◽

...

Keyword(s):

Built Environment ◽

Semen Quality ◽

Sperm Count ◽

Positive Association ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Progressive Motility ◽

History Of ◽

Total Motile Sperm Count

Abstract Background: There is growing interest in the potential impact of the physical environment on human fertility. This study aimed to explore the association between built environment and semen parameters among men who sought fertility evaluation . Methods: This is a cross-sectional study involving 5,886 men living in the Seoul Capital Area whose semen was tested at a single fertility center during 2016–2018. Environmental exposures evaluated were distance to fresh water (river and lake), the coast, major roadways, and neighborhood greenness measured by Normalized Difference Vegetation Index (NDVI). Outcome indicators were semen volume, sperm concentration, percentage of progressive motility, vitality, normal morphology, and total motile sperm count. We used linear regression to model standardized values of six semen quality indicators.Results: Majority of the study population (mean age 39 years) were white-collar workers, clerks, and service workers. None of the mean values of semen quality indicators showed linear trends across quartiles of built environment components. Linear associations between built environment features and semen quality indicators were not evident except for NDVI within 500 m and sperm vitality (β = 0.05 per 0.1-increase; 95% confidence interval (CI): 0.01, 0.09). The 2nd quartile of distance to fresh water was associated with lower progressive motility compared to the 1st quartile (β = −0.10; 95% CI: −0.17, −0.03). Proportion of vitality was higher among men in the 2nd quartile of distance to roadways than those in the 1st quartile (0.08; 95% CI: 0.01, 0.15). Men in the 2nd quartile of NDVI showed higher total motile sperm count than those in the 1st quartile (0.09; 95% CI: 0.01, 0.17). In multi-exposure model, the positive association between NDVI and vitality remained (0.03, 95% CI: 0.00, 0.06). Conclusions: This study contributes potential evidence regarding the impact of built environment on male fertility ; specifically, a positive association between residential greenness and percentage of sperm vitality among Korean men with a history of infertility .

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Association of Anxiety With Sperm Quality: a Multicentre Cross-sectional Study in China During the COVID-19 Outbreak

10.21203/rs.3.rs-664584/v1 ◽

2021 ◽

Author(s):

Yongfeng Wang ◽

Liting He ◽

Yunyi Yang ◽

Lihui Tu ◽

Jigao Yang ◽

...

Keyword(s):

Linear Regression ◽

Semen Quality ◽

Sperm Quality ◽

Sperm Count ◽

Sperm Concentration ◽

Cross Sectional Study ◽

Anxiety Symptoms ◽

Quality Analysis ◽

Cross Sectional ◽

Progressive Motility

Abstract Objectives: There is no report about association of anxiety on sperm quality during the COVID-19 epidemic. Purpose of this study was to investigate the relationship between anxiety and sperm quality during the COVID-19 outbreak in China.Methods: 896 sperm donors from 7 sperm banks in China were investigated, and passed the screening for sperm donation between 23 January 2020 and 8 June 2020. Semen quality analysis follows the standards of the WHO Fifth Edition Human Semen Examination and Processing Manual. Anxiety symptoms were assessed by the Generalized Anxiety Disorder Scal-7(GAD-7). Logistic regression and linear regression were used to identify the association between anxiety level and sperm quality.Results: Participants with anxiety status (N = 155; 17.3%) had lower sperm concentration (56.81 ± 32.70 vs. 47.21 ± 30.76 [106/mL]), sperm volume (3.58 ± 1.65 vs. 3.04 ± 1.69 [mL], P < 0.001), total sperm count (7.29 ± 1.23 vs. 6.56 ± 1.63 [106], P < 0.001), and progressive motility (50.86 ± 12.45 vs. 38.50 ± 17.00 [%], P < 0.001) than those without anxiety. Linear regression showed that anxiety symptoms was significantly associated with 8.13 (95% confidence interval [CI]: 2.51, 13.75), 0.49 (0.20, 0.79) ,51.05 (23.43, 78.68) and 12.15 (95% CI: 23.43, 78.68), reduction in sperm concentration, semen volume, and total sperm count and progressive motility respectively.Conclusions: This study revealed that anxiety symptoms were negatively associated with semen quality, and interaction was discovered between debt stress and anxiety.

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Association Between Meat Intake and Semen Parameters Among Iranian Infertile Men: A Cross-sectional Study

10.21203/rs.3.rs-29618/v1 ◽

2020 ◽

Author(s):

Reza Ghiasvand ◽

farahnaz haeri ◽

SeyyedPayam ShariatPanahi ◽

Laleh Dehghan Marvast

Keyword(s):

Semen Quality ◽

Cross Sectional Study ◽

Semen Parameters ◽

Sectional Study ◽

Cross Sectional ◽

Meat Intake ◽

Canned Tuna ◽

Infertile Men ◽

The Relationship ◽

Serving Size

Abstract Objective: Previous studies have proven the effect of dietary patterns on semen quality indicators, but research on the relationship between meat intake and semen quality is limited. Therefore, this study was conducted to investigate the relationship between Meat intake with semen quality.Methods: In this cross sectional study, 400 infertile men were recruited into study during their fertility investigation in Yazd Reproductive Sciences Institute Diagnosed by an andrologist according to the inclusion criteria. Multivariate logistic regression was used to determine the relationship between meat intake and semen parameters. All data were analyzed using SPSS V. 22 software.Results: We found that intake of canned tuna can have two different effects on sperm motility in infertile male. Intake of canned tuna according to the serving size stated in quartile 2, leads to a decrease in the percentage of immotile sperm from 52.93 (CI95%, 51.15-54.71) to 46.55 (CI95%, 44.56-48.54)(Ptrend=0.036). On the other hand, there is an increase in the percentage of immotile sperm from 46.55 (CI95%, 44.56-48.54) to 52.88 (CI95%, 50.94-54.82) in the highest quartile of canned tuna intake.Also, no significant relationship was observed between intake other types of meats and sperm quality indices.Conclusions: We found that intake of canned tuna,base on serving size of quartile 2, is associated with lower percentage of immotile sperm, on the other hand high intake of canned tuna increase percentage of immotile sperm in Iranian infertile men. More extensive studies are recommended in this regard.

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Sildenafil: efectos en la calidad espermática del hombre subfértil

Revista de Obstetricia y Ginecología de Venezuela ◽

10.51288/00810105 ◽

2021 ◽

Vol 81 (01) ◽

pp. 13-21

Author(s):

Elinor Moreno ◽

◽

Nellys Fonseca ◽

Sheyla Rodríguez

Keyword(s):

Informed Consent ◽

Therapeutic Option ◽

Sperm Concentration ◽

Cross Sectional Study ◽

Sperm Parameters ◽

Sectional Study ◽

Cross Sectional ◽

Progressive Motility ◽

Prior Informed Consent ◽

Before And After

Objective: To evaluate the effect of sildenafil on the sperm parameters of subfertile men who attended the fertility service of the Maternidad Concepción Palacios, between June 2011 and December 2013. Methods: A clinical, prospective, descriptive, experimental, cross-sectional study was conducted, prior informed consent, in 28 subfertile men with diagnosed asthenozoospermia, by performing two basal spermogram. Thereafter, they were given 50 mg of sildenafil, one hour before obtaining the sample, for a third and final spermogram. Results: Among the 28 patients studied, it was shown an increased progressive motility post-treatment in 21 patients (75%) which was statistically significant (p-0.000); the volume ejaculated before and after treatment had no statistically significant differences (p-0.405), as well as sperm concentration (p-1,000). Conclusions: The use of sildenafil in patients with diagnosed asthenozoospermia represents an economical therapeutic option, easy to acquire, and comply with in the treatment of this pathology. Keywords: Asthenozoospermia, Sildenafil, Semen.

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Iranian temporal changes in semen quality during the past 22 years: A report from an infertility center

International Journal of Reproductive BioMedicine ◽

10.18502/ijrm.v18i12.8027 ◽

2020 ◽

Author(s):

Serajeddin Vahidi ◽

Mohammad Reza Moein ◽

Fatemeh Yazdinejad ◽

Saeed Ghasemi-Esmailabad ◽

Nima Narimani

Keyword(s):

Semen Quality ◽

Semen Analysis ◽

Sperm Concentration ◽

Cross Sectional Study ◽

Temporal Changes ◽

Systemic Review ◽

Semen Parameters ◽

Cross Sectional ◽

Clinical Center ◽

Group 2

Background: Despite numerous reports about temporal changes in semen quality from all over the world, the debates continue. The latest systemic review has shown an overtime decrease in semen quality worldwide. Objective: To assess the temporal changes in the semen quality among Iranian population referred to an infertility center. Materials and Methods: In this retrospective cross-sectional study, semen parameters including concentration, motility, and morphology were compared between Iranian men reffered to Research and Clinical Center for Infertility, Yazd between 1990 to 1992 (group 1, n = 707) and 2010 to 2012 (group 2, n = 1108). Demographic characteristics and semen analysis were collected from the records. The effect of age on semen parameters was also investigated. Results: Despite the increase in sperm concentration l in group 2, sperm with normal morphology decreased significantly (p < 0.001). Grade-A motility decreased (p < 0.001), grade B motility increased (p < 0.001), and grade C and D motile sperm remained constant (p = 0.303 and p = 0.315, respectively). Also, no significant correlation between the age and semen parameters were observed. Conclusion: This study showed inconsistent temporal changes in the participant semen quality. Significant temporal decline were obtained between various semen parameters, sperm morphology and grade A motility. These results should be further evaluated by larger studies in the future. Key words: Infertility, Semen quality, Temporal changes.

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Occupational manganese exposure, reproductive hormones, and semen quality in male workers: A cross-sectional study

Toxicology and Industrial Health ◽

10.1177/0748233718810109 ◽

2018 ◽

Vol 35 (1) ◽

pp. 53-62 ◽

Cited By ~ 5

Author(s):

Haibo Yang ◽

Jifeng Wang ◽

Xinxin Yang ◽

Fengdi Wu ◽

Zhipeng Qi ◽

...

Keyword(s):

Semen Quality ◽

Cross Sectional Study ◽

Reproductive Hormones ◽

Exposed Group ◽

Control Group ◽

Sectional Study ◽

Cross Sectional ◽

Progressive Motility ◽

Linear Association ◽

Male Workers

It has been found that exposure to manganese (Mn) could induce reproductive dysfunction, but its occupational risk in male workers is unclear. This study aims to assess the association of occupational Mn exposure with reproductive hormones and semen quality in a cross-sectional study. Urinary Mn, semen quality, and reproductive hormones were explored in 84 male workers occupationally exposed to Mn and 92 referents. Multiple linear regression analyses were used to assess the relationship. Urinary Mn levels in Mn-exposed workers ranged from 0.56 to 34.25 µg/L, and the average level was 15.92 ± 8.49 µg/L. Compared with the control group, gonadotropin-releasing hormone (GnRH) levels and luteinizing hormone (LH) levels increased significantly and the levels of testosterone (TSTO) decreased significantly in the Mn-exposed group. There was a significant positive linear association between urinary Mn and GnRH and LH, while the linear association between urinary Mn and TSTO was negative. Sperm progressive motility and total motility decreased significantly in the Mn-exposed group. There was a significantly negative linear association between urinary Mn and sperm progressive motility and total motility. In conclusion, occupational Mn exposure was inversely associated with reproductive health of male workers, resulting in the abnormality of hormones secretion and decrease of sperm motility.

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