scholarly journals Postprandial Effect of Yogurt Enriched with Anthocyanins from Riceberry Rice on Glycemic Response and Antioxidant Capacity in Healthy Adults

Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 2930
Author(s):  
Tanisa Anuyahong ◽  
Charoonsri Chusak ◽  
Thavaree Thilavech ◽  
Sirichai Adisakwattana
Keyword(s):  
Antioxidant Capacity ◽  
Plasma Glucose ◽  
Healthy Adults ◽  
Trolox Equivalent Antioxidant Capacity ◽  
Subjective Rating ◽  
Glycemic Response ◽  
Subjective Ratings ◽  
Reducing Ability ◽  
Plasma Antioxidant Capacity ◽  
Plasma Antioxidant

The pigment of riceberry rice has been reported to contain anthocyanins which act as a free radical scavenger and inhibitor of carbohydrate digestive enzymes. Since the probiotic yogurt incorporated with the pigment of riceberry rice extract was previously developed, the present study was aimed to investigate the acute effect of riceberry rice yogurt consumption on postprandial glycemic response, antioxidant capacity, and subjective ratings in healthy adults. In a cross-over design, 19 healthy participants were randomized to consume 350 g of yogurt supplemented with 0.25% (w/w) riceberry rice extract or the control yogurt. Postprandial plasma glucose, antioxidant status, and subjective ratings were measured at fasting and intervals (0–3 h) after ingestion of yogurt. The primary outcome was glycemic response; the secondary outcomes were plasma antioxidant capacity. In comparison to the yogurt control, riceberry rice yogurt reduced plasma glucose concentration after 30 min of consumption. The incremental area under the curve (iAUC) was significantly lower after riceberry rice yogurt load than after the control yogurt load. The consumption of riceberry yogurt caused an acute increase in plasma ferric reducing ability of plasma (FRAP), Trolox equivalent antioxidant capacity (TEAC), and oxygen radical absorbance capacity (ORAC) from the baseline values after 60 min of 0.25 ± 0.06 mM FeSO4, 253.7 ± 35.5 mM Trolox equivalents, and 166.8 ± 28.9 mM Trolox equivalents, respectively. Furthermore, the iAUCs for FRAP, TEAC, ORAC, and protein thiol were higher in riceberry yogurt consumption compared with the control yogurt (1.6-, 1.6-, 2.9-, and 1.9-fold, respectively). A decrease in iAUC for plasma malondialdehyde (MDA) concentration was also observed in the riceberry yogurt group. However, consumption of riceberry rice yogurt and control yogurt showed similar subjective rating scores of hunger, desire to eat, fullness, and satiety. In conclusion, acute consumption of riceberry rice yogurt suppressed postprandial glucose level and improved plasma antioxidant capacity in healthy volunteers.

Effect of Propofol, Sevoflurane and Desflurane on Systemic Redox Balance

2007 ◽  
Vol 20 (3) ◽  
pp. 585-593 ◽  
Author(s):  
G. Cinnella ◽  
G. Vendemiale ◽  
M. Dambrosio ◽  
G. Serviddio ◽  
P.L. Pugliese ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Antioxidant Properties ◽  
Redox Balance ◽  
Trolox Equivalent Antioxidant Capacity ◽  
Sodium Thiopental ◽  
Blood Samples ◽  
Plasma Antioxidant Capacity ◽  
Trolox Equivalent ◽  
Plasma Antioxidant ◽  
Group D

We studied the effects of Propofol, Desflurane, and Sevoflurane on the systemic redox balance in patients undergoing laparohysterectomy. We measured blood concentration of glutathione (GSH), plasma antioxidant capacity (Trolox Equivalent Antioxidant Capacity-TEAC), and lipid peroxidation products (malondialdehyde (aMDA) and 4-hydroxynonenal (aHNE) protein adducts). Sixty patients were randomly placed into three groups of twenty people each. In Group P anesthesia was induced with Propofol 2 mg/kg and maintained with 12–10–8 mg/kg/min; in Groups S and D anesthesia was induced with 3 mg/kg Sodium Thiopental and maintained with 2% Sevoflurane and 6% Desflurane, respectively. Blood samples were collected prior to induction (T0bas), 60min and 24h postoperatively (T160' and T224 h). In Group P, GSH increased on T160' (p<0.02) and returned to baseline on T24h, while TEAC remained unmodified; in Groups S, GSH and TEAC decreased on T160' (p<0.01 vs. T0bas, p<0.03 vs. T0bas, respectively); in Group D, on T160' there was a slight decrease of GSH and TEAC. The levels of aMDA slightly decreased throughout the study periods in Group P, increased in Group D, and remained stable in Group S. Propofol showed antioxidant properties, while Sevoflurane and Desflurane seemed to shift the redox balance towards oxidation, yet without inducing overt oxidative damage.

scholarly journals The Influence of ProbioticLactobacillus caseiin Combination with Prebiotic Inulin on the Antioxidant Capacity of Human Plasma

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Paulina Kleniewska ◽  
Arkadiusz Hoffmann ◽  
Ewa Pniewska ◽  
Rafał Pawliczak
Keyword(s):  
Antioxidant Capacity ◽  
Human Plasma ◽  
Antioxidant Properties ◽  
Positive Influence ◽  
Reducing Ability ◽  
Plasma Antioxidant Capacity ◽  
Synbiotic Supplementation ◽  
Plasma Antioxidant ◽  
And Control ◽  
Gpx Activity

The aim of the present study was to assess whether probiotic bacteriaLactobacillus casei(4 × 108 CFU) influences the antioxidant properties of human plasma when combined with prebiotic Inulin (400 mg). Experiments were carried out on healthy volunteers (n=32). Volunteers were divided according to sex (16 male and 16 female) and randomly assigned to synbiotic and control groups. Blood samples were collected before synbiotic supplementation and after 7 weeks, at the end of the study. Catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx) activity, and the ferric reducing ability of plasma (FRAP) in human plasma were examined. The administration of synbiotics containingL. caseiplus Inulin resulted in a significant increase in FRAP values (p=0.00008) and CAT activity (p=0.02) and an insignificant increase in SOD and GPx activity compared to controls. Synbiotics containingL. casei(4 × 108 CFU) with prebiotic Inulin (400 mg) may have a positive influence on human plasma antioxidant capacity and the activity of selected antioxidant enzymes.

A Novel Method for Measuring Antioxidant Capacity and its Application to Monitoring the Antioxidant Status in Premature Neonates

1993 ◽  
Vol 84 (4) ◽  
pp. 407-412 ◽  
Author(s):  
Nicholas J. Miller ◽  
Catherine Rice-Evans ◽  
Michael J. Davies ◽  
Vimala Gopinathan ◽  
Anthony Milner
Keyword(s):  
Antioxidant Capacity ◽  
Radical Scavenging ◽  
Reference Population ◽  
Trolox Equivalent Antioxidant Capacity ◽  
Antioxidant Compounds ◽  
Automated Method ◽  
Plasma Antioxidant Capacity ◽  
Total Antioxidant ◽  
Trolox Equivalent ◽  
Plasma Antioxidant

1. A new method has been developed for measuring the total antioxidant capacity of body fluids and drug solutions, based on the absorbance of the ABTS*+ radical cation. 2. An automated method for use on a centrifugal analyser, as well as a manual method, is described. 3. The procedure has been applied to physiological antioxidant compounds and radical-scavenging drugs, and an antioxidant ranking was established based on their reactivity relative to a 1.0 mmol/l Trolox standard. 4. The Trolox equivalent antioxidant capacity of plasma from an adult reference population has been measured, and the method optimized and validated. 5. The method has been applied to investigate the total plasma antioxidant capacity of neonates and how this may be compromised in prematurity.

scholarly journals Relationship between vitamin intake and total antioxidant capacity in elderly adults

2016 ◽  
Vol 21 (2) ◽  
pp. 167 ◽  
Author(s):  
Miriam Lucia Ojeda Arredondo ◽  
Magda Catalina Pinilla Betancourt ◽  
Martha Lucia Borrero Yoshida ◽  
Gonzalo Sequeda ◽  
Vivian Maritza Castro Herrera ◽  
...  
Keyword(s):  
Vitamin A ◽  
Antioxidant Capacity ◽  
Fruits And Vegetables ◽  
Natural Antioxidants ◽  
Absorption Capacity ◽  
Trolox Equivalent Antioxidant Capacity ◽  
P Value ◽  
Food Composition Tables ◽  
Plasma Antioxidant Capacity ◽  
Plasma Antioxidant

<p>The consumption of foods high in natural antioxidants, like fruits and vegetables, is associated with a lower risk of oxidative stress-related diseases. The aim of this study was to establish the relationship between the plasma antioxidant capacity in adults over fifty and their intake of vitamin A, C, and E. We evaluated 118 24-hour recalls of intake of foods. The intake of vitamin A, C, and E was quantified using food composition tables. We quantified plasma phenols using the Folin-Ciocalteu method. The antioxidant capacity was determined using the Trolox Equivalent Antioxidant Capacity (TEAC) and Oxygen Radical Absorption Capacity (ORAC) methods. Correlation analyses were performed between the studied variables and a positive correlation was found in most cases. However, none of the correlations was statistically significant. In all cases p-value was &gt;0.05. The quantification of nutrient intake is not an adequate predictor of plasma antioxidant capacity in individuals over fifty</p>

scholarly journals Increased antioxidant capacity in the plasma of dogs after a single oral dosage of tocotrienols

2011 ◽  
Vol 106 (S1) ◽  
pp. S116-S119 ◽  
Author(s):  
Jens Raila ◽  
Sascha Rohn ◽  
Florian J. Schweigert ◽  
Getu Abraham
Keyword(s):  
Antioxidant Capacity ◽  
Oral Dosage ◽  
Trolox Equivalent Antioxidant Capacity ◽  
Total Plasma ◽  
Beagle Dogs ◽  
Plasma Antioxidant Capacity ◽  
Trolox Equivalent ◽  
Plasma Antioxidant ◽  
Time Point

The intestinal absorption of tocotrienols (TCT) in dogs is, to our knowledge, so far unknown. Adult Beagle dogs (n 8) were administered a single oral dosage of a TCT-rich fraction (TRF; 40 mg/kg body weight) containing 32 % α-TCT, 2 % β-TCT, 27 % γ-TCT, 14 % δ-TCT and 25 % α-tocopherol (α-TCP). Blood was sampled at baseline (fasted), 1, 2, 3, 4, 5, 6, 8 and 12 h after supplementation. Plasma and chylomicron concentrations of TCT and α-TCP were measured at each time point. Plasma TAG were measured enzymatically, and plasma antioxidant capacity was assessed by the Trolox equivalent antioxidant capacity assay. In fasted dogs, levels of TCT were 0·07 (sd 0·03) μmol/l. Following the administration of the TRF, total plasma TCT peaked at 2 h (7·16 (sd 3·88) μmol/l; P < 0·01) and remained above baseline levels (0·67 (sd 0·44) μmol/l; P < 0·01) at 12 h. The TCT response in chylomicrons paralleled the increase in TCT in plasma with a maximum peak (3·49 (sd 2·06) μmol/l; P < 0·01) at 2 h post-dosage. α-TCP was the major vitamin E detected in plasma and unaffected by TRF supplementation. The Trolox equivalent values increased from 2 h (776 (sd 51·2) μmol/l) to a maximum at 12 h (1130 (sd 7·72) μmol/l; P < 0·01). The results show that TCT are detected in postprandial plasma of dogs. The increase in antioxidant capacity suggests a potential beneficial role of TCT supplementation in the prevention or treatment of several diseases in dogs.

scholarly journals Synergies of herbal teas on improved plasma antioxidant capacity and postprandial hypoglycemic response in healthy adults

2021 ◽  
Vol 13 ◽  
Author(s):  
Anoma Chandrasekara ◽  
Apeksha Herath ◽  
Rupika Abeynayake ◽  
Adriano Costa De Camargo ◽  
Fereidoon Shahidi
Keyword(s):  
Antioxidant Capacity ◽  
High Performance ◽  
Antioxidant Activities ◽  
Healthy Adults ◽  
Herbal Tea ◽  
Plasma Antioxidant Capacity ◽  
Liquid Chromatography Tandem Mass ◽  
Food Cultures ◽  
Plasma Antioxidant ◽  
Glucose Reduction

Herbal teas play a major role in the global traditional food cultures.  There are a variety of herbal teas used for general wellness and prevention and management of chronic diseases including diabetes mellitus. The present study aimed to determine the phenolic content and antioxidant activities of herbal teas prepared with matured jackfruit (Artocarpus heterophyllus) leaves after senescence and abscission, and dried Cassia (Cassia auriculata) flowers and buds.  The sensory evaluation was performed using 50 untrained panelists to determine the amount of herbal ingredient to be used in the preparation of herbal tea. Furthermore, the potential single dose efficacy of three herbal teas, namely, Jackfruit leaves tea (JLT), Cassia flower tea (CFT) and mixed jackfruit leaves and Cassia flower tea (JCT) on postprandial glycemic response and plasma antioxidant capacity (PAC) of healthy adults were investigated. Phenolics were identified using high performance liquid chromatography–tandem mass spectrometry. A randomized crossover study was led with 16 healthy adults who consumed 250 mL of freshly prepared herbal beverage with 50 g glucose and 50 g glucose in 250 mL water as the control randomly within three visits with a washout period of four days between two visits. Blood samples were collected using microcapillary tubes at the baseline and postprandial at 30, 45, 60, 90, and 120 min. The plasma was analyzed for glucose concentration (PGC) and PAC.  JLT and JCT showed a significant reduction of PGC compared to the control at 30, 45, and 60 min time points.  JLT and JCT showed higher efficacy in plasma glucose reduction than CFT.  All herbal teas significantly increased PAC at the end of 120 min post ingestion.  Further research is warranted to examine the synergistic effect of two mixed ingredients for herbal tea and the long-term efficacy of multiple dose ingestion of respective herbal teas in the prevention and management of hyperglycemia and type 2 diabetes.

scholarly journals Does dihydropyrimidine dehydrogenase level modify plasma antioxidant capacity in colorectal cancer patients treated with fluoropyrimidines? 

Folia Medica ◽  
2021 ◽  
Vol 63 (5) ◽  
pp. 760-767
Author(s):  
Velko Minchev ◽  
Nadya Hristova-Avakumova ◽  
Kalina Kamenova ◽  
Liliya Atanasova ◽  
Marin Angelov ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Antioxidant Capacity ◽  
Cancer Patients ◽  
Statistical Significance ◽  
Dihydropyrimidine Dehydrogenase ◽  
Cancer Type ◽  
Reducing Ability ◽  
Plasma Antioxidant Capacity ◽  
Colorectal Cancer Patients ◽  
Plasma Antioxidant

Introduction: Colorectal cancer is the third most common cancer type worldwide. Fluoropyrimidines and their prodrug-based regimens are widely applied as primary medications. The main enzyme responsible for the rate-limiting step in pyrimidine and for the 5-fluorouracil catabolism is dihydropyrimidine dehydrogenase (DPD). Aim: We aimed to screen DPD level and the changes of plasma antioxidant capacity of colorectal cancer patients on 5-fluorouracil regimen.&nbsp; Materials and methods: Human DPD Elisa Kit based on sandwich enzyme-linked immune-sorbent assay and spectrophotometric methods (FRAP and ABTS) were used in the study. Results: No statistically significant changes in plasma scavenging activity according to the results obtained in the ABTS system have been observed after evaluating all patients and considering DPD concentration. A decrease of the ferric reducing ability of patients&rsquo; plasma taken after the administered treatment was found. The increase of DPD level is accompanied by a decrease in the p values and therefore the statistical significance of the differences increases. Conclusions: Based on the aforementioned observations, it could be concluded that some aspects of plasma antioxidant capacity and individuals&rsquo; antioxidant status might be involved in the pathogenesis of the disease and could be altered by the activity of some enzymes. The cancer therapy in question, by the specificity of its mechanism of action, can modify patient&rsquo;s oxidative status.

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