scholarly journals Hematological Features in Sheep with IgG and IgM Antibodies against Borrelia burgdorferi sensu lato

Pathogens ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 164
Author(s):  
Labrini V. Athanasiou ◽  
Victoria M. Spanou ◽  
Eleni G. Katsogiannou ◽  
Panagiotis D. Katsoulos
Keyword(s):  
Borrelia Burgdorferi ◽  
Rural Areas ◽  
Blood Analysis ◽  
Borrelia Burgdorferi Sensu Lato ◽  
Igm Antibodies ◽  
Group A ◽  
Group B ◽  
Group D ◽  
Immunofluorescence Antibody

Exposure of sheep to Borreliaburgdorferi sensulato (s.I.) complex, the causative agent of Lyme borreliosis (LB), has been reported in tick-abundant areas worldwide, while no data have been reported in Greece. The aim of the study was to identify the hematological alterations in sheep with seropositivity against Borrelia burgdorferi (s.I.). Blood samples were obtained from 318 tick infested sheep for blood analysis and serological determination of IgG and IgM antibodies against B. burgdorferi by indirect immunofluorescence antibody (IFA) assay after exclusion of endo-ectoparasites and other tick-borne infections. A total number of 162 sheep met the inclusion criteria, allocated in four groups based on the presence or absence of IgG and/or IgM; sheep found negative for IgM and IgG (Group A), positive for IgM (Group B), positive for both IgM and IgG (Group C) and positive for IgG (Group D). Anemia, thrombocytopenia and normal or decreased leukocyte count, mainly due to lymphopenia were the main hematological features observed in seropositive sheep. The presence of these features raises the suspicion of Borrelia infection in tick infested sheep. The seropositivity of 23.58% in sheep raises concerns of Borrelia circulation, especially in rural areas and potential risk of transmission to humans.

Increased aortic PGI2 and plasma lyso-PAF in the unclipped one-kidney hypertensive rat

1986 ◽  
Vol 251 (6) ◽  
pp. H1361-H1364 ◽  
Author(s):  
H. M. McGowan ◽  
R. Vandongen ◽  
J. P. Codde ◽  
K. D. Croft
Keyword(s):  
Blood Pressure ◽  
Hydrolysis Product ◽  
Platelet Activating Factor ◽  
Hypertensive Rats ◽  
Hypertensive Rat ◽  
Group A ◽  
The One ◽  
Group B ◽  
Group D

Previous studies have implicated vasodilatory prostaglandins (PGs) in the reversal of hypertension following unclipping in the one-kidney, one-clip (1K,1C) hypertensive rat. The capacity of the aorta to synthesize prostacyclin (PGI2) was compared in clipped (group A, n = 9), unclipped (group B, n = 8 and group D, n = 9), and sham-unclipped (group C, n = 9) 1K,1C hypertensive rats. The involvement of platelet-activating factor (PAF), a potent renal antihypertensive phospholipid, in the reversal of renal clip hypertension was also examined. Hypertensive rats [systolic blood pressure (BP) greater than 180 mmHg] were fed a synthetic diet for 4 wk, after which group A was killed immediately, group C was sham-unclipped, and groups B and D unclipped and killed 24 h later. Blood was drawn for the measurement of plasma lyso-PAF (the precursor of PAF) and the aorta removed for determination of 6-ketoprostaglandin F1 alpha (6-keto-PGF1 alpha, the stable hydrolysis product of PGI2). BP fell substantially in the unclipped rats (groups B and D) but did not change in the sham-unclipped rats (group C). Mean aortic 6-keto-PGF1 alpha was increased in the unclipped groups [group B, 15.4 +/- 2.4 (SE) ng/mg; group D, 10.8 +/- 2 ng/mg] compared with group A (7.7 +/- 1 ng/mg) and group C (7.1 +/- 1 ng/mg) (H = 13.74, P less than 0.01). Plasma lyso-PAF was also significantly increased in the unclipped (group D, 261 +/- 26 ng/ml) vs. the sham-unclipped group (group C, 211 +/- 23 ng/ml, P less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)

scholarly journals Evaluation of complements serum level (C3 and C4) in pregnant women with history of toxoplasmosis

2011 ◽  
Vol 5 (2) ◽  
pp. 12-16
Author(s):  
Dunya F. Salloom ◽  
Harith S. AL-Warid ◽  
Ali H. Abbas
Keyword(s):  
Immune Response ◽  
Serum Level ◽  
Pregnant Women ◽  
Normal Pregnancy ◽  
Igm Antibodies ◽  
History Of ◽  
Group A ◽  
Group B ◽  
Group D

C3 and C4 serum level were evaluated in 30 pregnant women which divided into groups: Group A16 (53.3%) (Pregnant women with history of abortion and positive anti toxoplasma IgM antibodies), Group B10 (33%) (Normal pregnancy women with no history of abortion or Toxoplasmosis.), Group C6 (20%) (Pregnant women with history of two abortion and positive anti toxoplasma IgM), group D 10 (33.3%) (Pregnant women with history of only one abortion and positive anti- toxoplasma IgM), group E 4 (13.3%) (Pregnant women with history of only one abortion and negative anti-toxoplasma IgM). The results showed that highest level of both C3 and C4 in women with positive anti toxplasma IgM and history of one or two abortion/abortions while the lowest level of these two complements were in women with negative anti toxplasma IgM even they had one abortion or no abortion. There is significant differences in concentration of C3 ( 189.7 ± 20.3 mg/dl ) and C4 ( 59.3 ± 7.5 mg/dl ) in group A and C3 ( 189.6 ± 17.7 mg/dl ) and C4 ( 63.08 ± 4.7 mg/dl) when compared with group B and E, and the result showed statistical differences in C4 concentration between group C and D at P< 0.05. We conclude that complement was play role in immune response of pregnant women especially against toxoplasmosis that cause abortion to these women.

scholarly journals KARAKTERISASI MORFOLOGI DAUN DAN BUNGA BEBERAPA VARIETAS Hoya coronaria DARI KAWASAN HUTAN KERANGAS AIR ANYIR, BANGKA

2018 ◽  
Vol 2 (1) ◽  
pp. 1-9
Author(s):  
Putri Deswanti ◽  
Yulian Fakhrurrozi ◽  
Sri Rahayu
Keyword(s):  
Morphological Characteristics ◽  
Flower Color ◽  
Group A ◽  
Yellow Corolla ◽  
Heath Forest ◽  
Group B ◽  
Munsell Color Chart ◽  
Group D ◽  
Descriptive Method

Hoya coronaria was found in Heath Forest Air Anyir, Bangka in various flower color. Characterization based on morphological characteristics need to clear up the differences between varieties. This research aims to observe morphological variation of six varieties of H. coronaria from Heath Forest Air Anyir, Bangka based on morphology vegetative and flower morphology. The descriptive method was used to describe the morphological character. Determination of color based on Munsell Color Chart for Plant Tissues. The six samples of different varieties was used which has different flower color as follow respectively: yellow corolla with pink corona (var1); yellow corolla with white corona (var2); yellow corolla with pink honey line and pink corona (var3); pink corolla with pink honey line and pink corona (var4); pink corolla with pink honey line and white corona (var5); and white corolla with white corona (var6). The six varieties have different characteristic of vegetative and flower part both on qualitative and quantitative measurement. The cluster analyses resulted two sister groups. The first group (group A) consisted of var3, var4, var5, and var6, and the second group (group B) consisted of var1 and var2. Groups A was consisted of two smaller groups, namely group C and group D. Group C consisted of var3, var4 and var5, while group D consisted of var6

scholarly journals Effects of calcium carbonate, potassium iodide and zinc sulphate in lead induced toxicities in rat model

1970 ◽  
Vol 4 (2) ◽  
pp. 123-127
Author(s):  
MM Haque ◽  
MA Awal ◽  
M Mostofa ◽  
MMH Sikder ◽  
MA Hossain
Keyword(s):  
Body Weight ◽  
Calcium Carbonate ◽  
Potassium Iodide ◽  
Zinc Sulphate ◽  
The Body ◽  
Postmortem Changes ◽  
Group A ◽  
Group B ◽  
Group D

A study was carried out to find out the effects of calcium carbonate, potassium iodide and zinc sulphate in lead induced toxicities in rat with the observation of toxic signs, postmortem changes and determination of lead quantity in different organs of the body. Twenty-five long Evans rats weighing between 202-305g were randomly divided into five groups keeping group A as untreated control. Rest four groups (B, C, D & E) were treated with lead acetate @ 20mg/kg body weight in addition, rats of groups C, D & E were given Calcium carbonate (50mg/kg body weight), potassium iodide (20mg/kg bwt) and zinc sulphate (10mg/kg bwt.) respectively. Treatments were continued for 42 consecutive days. Rats of group B showed reduction in fecal consumption, anxiety, indigestion, fatigue, muscle tremor, paralysis and ruffled hair coat. However, rats of group C were apparently normal but rats of group D and E showed mild toxic signs of similar nature. On postmortem examination, severe congestion and blackish discoloration with enlargement of the liver, kidney, spleen and inflammation of the gastric mucosa were observed in rats of group B. However, these changes were less severe in other groups. The significant reduction of lead in blood, liver, kidney and brain was observed in rats of group C, D and E in comparison to group B. In addition, significant reduction of lead content was observed in femur of group C only. The present findings revealed that during lead exposure administration of calcium carbonate may be effective in modifying and preventing lead deposition in tissues followed by zinc sulphate and potassium iodide in rat. Key words: Toxicity, lead, calcium carbonate, potassium iodide, zinc sulphate, rat DOI = 10.3329/bjvm.v4i2.1295 Bangl. J. Vet. Med. (2006). 4 (2): 123-127

scholarly journals Comparative efficacy of imported fowl pox virus vaccine with locally produced one in backyard chicks

1970 ◽  
Vol 6 (1) ◽  
pp. 23-26 ◽  
Author(s):  
MR Islam ◽  
MSR Khan ◽  
MA Islam ◽  
MEH Kayesh ◽  
MR Karim ◽  
...  
Keyword(s):  
Virus Vaccine ◽  
Control Group ◽  
Post Vaccination ◽  
History Of ◽  
Group A ◽  
Group B ◽  
Protection And Control ◽  
And Control ◽  
Group D

A total of 80 experimentally reared backyard chicks with the history of non-vaccinated parents to FPV vaccine were used for the determination of persistence of maternally derived antibody in chicks and to compare the efficacy of Poxine® and DLS-FPV vaccine in protecting the chicks. Chicks were divided into five groups namely group A, B, C, D and E where each group contained 15 chicks except group A contained 20 chicks which was also used to determine the persistence of maternally derived antibody (MDA). Birds of group B and C were vaccinated with DLS-FPV at day 22 and 18 respectively through wing web puncture (WWP), whereas group D and E were vaccinated with Poxine® at day 36 and 18 respectively. Sera were randomly colleted from 10 chicks of each group at 7, 14 and 21 days of post vaccination for the determination of antibody titre using PHA test. Ten chickens from each group were challenged three weeks post vaccination with 106 EID50/0.1ml. "Take reaction" was recorded to assess the better immune response in different groups after vaccination. Birds of group B, C, D and E showed 100, 86.67, 93 and 86.67% "take reaction", respectively. The highest Mean PHA titre was found 217.60 ± 19.55 in the chicks of group B. After challenge, the birds of group B and D showed 100% protection, whereas birds of group C and E showed 93.33% protection and control group showed no protection. From the results of PHA test it may be concluded that both Poxine® and DLS-FPV vaccines are equally suitable and the chicks of nonvaccinated origin might be vaccinated with DLS-FPV at day 18 or 22 and 36 in case of Poxine® fowl pox virus vaccine. Key words: Efficacy, fowl pox virus vaccine, backyard chicks, age DOI = 10.3329/bjvm.v6i1.1334 Bangl. J. Vet. Med. (2008). 6 (1): 23-26

Survival of classic swine fever virus in hams made from the meat of pigs vaccinated with the PAV-250 strain and unvaccinated pigs

2019 ◽  
Vol 10 (3) ◽  
pp. 536-551
Author(s):  
Heidi Amezcua Hempel ◽  
María Salud Rubio Lozano ◽  
Eliseo Manuel Hernández Baumgarten ◽  
Pablo Correa Girón † ◽  
Oscar Torres Ángeles ◽  
...  
Keyword(s):  
Reference Strain ◽  
Clinical Signs ◽  
Classical Swine Fever ◽  
Fever Virus ◽  
Direct Immunofluorescence ◽  
Biometric Analysis ◽  
Treatment Groups ◽  
Group A ◽  
Group B ◽  
Group D

The study was to determine the presence of Classical Swine Fever virus (CSFv), in the meat of vaccinated pigs with the PAV-250 strain and then challenged using the same strain. Five treatment groups were established (each with four pigs). Group A: Pigs thatwere fed with processed hams from negative animals; Group B: Pigs that were fed with processed hams from commercial pigs inoculated with the ALD (reference strain) (titre of 104.0/ml); Group C: Pigs fed with processed hams from pigs infected with the virulent ALD strain (titre of 102.5/ml); Group D: Pigs fed with processed hams from pigs vaccinated with the PAV-250 strain and challenged with the ALD strain (titre of 101.1/ml); and Group E: Pigs fed with processed hams from pigs vaccinated with two doses of the PAV-250 strain and challenged with the ALD strain (negative). Blood samples were taken at d 1, 5, 10, 15 and 20 for biometric analysis. Groups B, C and D manifested clinical signs of CSFv: 40 °C temperature, anorexia, paralysis, vomiting, diarrhea, tremor, hirsute hair and cyanosis. Pigs were slaughtered and necropsies performed to identify lesions in tissues. Results of direct immunofluorescence testing of tissues were positive and the virus was recovered. Under these study conditions, it was found that CSFv resisted the cooking method at 68 °C for 40 min in hams from unvaccinated pigs, and that the virus was able to transmit the disease to healthy unvaccinated pigs, whereas the hams from the vaccinated animals did not transmit the virus.

scholarly journals The Role of Obesity in Predicting the Clinical Outcomes of COVID-19

Obesity Facts ◽  
2021 ◽  
pp. 1-9
Author(s):  
Serdar Sahin ◽  
Havva Sezer ◽  
Ebru Cicek ◽  
Yeliz Yagız Ozogul ◽  
Murat Yildirim ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Health Care Providers ◽  
Study Groups ◽  
Normal Weight ◽  
Overweight And Obesity ◽  
Care Providers ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Group D

<b><i>Introduction:</i></b> The aim of this was to describe the predictors of mortality related to COVID-19 infection and to evaluate the association between overweight, obesity, and clinical outcomes of COVID-19. <b><i>Methods:</i></b> We included the patients &#x3e;18 years of age, with at least one positive SARS-CoV-2 reverse transcriptase-polymerase chain reaction. Patients were grouped according to body mass index values as normal weight &#x3c;25 kg/m<sup>2</sup> (Group A), overweight from 25 to &#x3c;30 kg/m<sup>2</sup> (Group B), Class I obesity 30 to &#x3c;35 kg/m<sup>2</sup> (Group C), and ≥35 kg/m<sup>2</sup> (Group D). Mortality, clinical outcomes, laboratory parameters, and comorbidities were compared among 4 groups. <b><i>Results:</i></b> There was no significant difference among study groups in terms of mortality. Noninvasive mechanical ventilation requirement was higher in group B and D than group A, while it was higher in Group D than Group C (Group B vs. Group A [<i>p</i> = 0.017], Group D vs. Group A [<i>p</i> = 0.001], and Group D vs. Group C [<i>p</i> = 0.016]). Lung involvement was less common in Group A, and presence of hypoxia was more common in Group D (Group B vs. Group A [<i>p</i> = 0.025], Group D vs. Group A [<i>p</i> &#x3c; 0.001], Group D vs. Group B [<i>p</i> = 0.006], and Group D vs. Group C [<i>p</i> = 0.014]). The hospitalization rate was lower in Group A than in the other groups; in addition, patients in Group D have the highest rate of hospitalization (Group B vs. Group A [<i>p</i> &#x3c; 0.001], Group C vs. Group A [<i>p</i> &#x3c; 0.001], Group D vs. Group A [<i>p</i> &#x3c; 0.001], Group D vs. Group B [<i>p</i> &#x3c; 0.001], and Group D vs. Group C [<i>p</i> = 0.010]). <b><i>Conclusion:</i></b> COVID-19 patients with overweight and obesity presented with more severe clinical findings. Health-care providers should take into account that people living with overweight and obesity are at higher risk for COVID-19 and its complications.

scholarly journals AB0422 LEFT VENTRICULAR ABNORMALITIES IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS FOLLOWED BY SEQUENTIAL ECHOCARDIOGRAPHY

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1510.1-1511
Author(s):  
T. Kuga ◽  
M. Matsushita ◽  
K. Tada ◽  
K. Yamaji ◽  
N. Tamura
Keyword(s):  
Lupus Erythematosus ◽  
Systolic Dysfunction ◽  
Left Ventricular ◽  
Monocyte Count ◽  
Lv Dysfunction ◽  
Group A ◽  
Group B ◽  
Lv Diastolic Dysfunction ◽  
Group D

Background:Cardiovascular disease (CVD) is detected in up to 50% of systemic lupus erythematosus (SLE) patients1and major cause of death2. Even clinically silent SLE patients can develop left ventricular (LV) diastolic dysfunction3. Proper echocardiographic follow up of SLE patients is required.Objectives:To clarify how the prevalence of LV abnormalities changes over follow-up period and identify the associated clinical factors, useful in suspecting LV abnormalities.Methods:29 SLE patients (24 females and 5 men, mean age 52.8±16.3 years, mean disease duration 17.6±14.5 years) were enrolled. All of them underwent echocardiography as the baseline examination and reexamined over more than a year of follow-up period(mean 1075±480 days) from Jan 2014 to Sep 2019. Patients complicated with pulmonary artery hypertension, deep venous thrombosis or pulmonary embolism and underwent cardiac surgery during the follow-up period were excluded. Left ventricular(LV) systolic dysfunction was defined as ejection fraction (EF) < 50%. LV diastolic dysfunction was defined according to ASE/EACVI guideline4. LV dysfunction (LVD) includes one or both of LV systolic dysfunction and LV diastolic function. Monocyte to HDL ratio (MHR) was calculated by dividing monocyte count with HDL-C level.Prevalence of left ventricular abnormalities was analysed at baseline and follow-up examination. Clinical characteristics and laboratory data were compared among patient groups as follows; patients with LV dysfunction (Group A) and without LV dysfunction (Group B) at the follow-up echocardiography, patients with LV asynergy at any point of examination (Group C) and patients free of LV abnormalities during the follow-up period (Group D).Results:At the baseline examination, LV dysfunction (5/29 cases, 13.8%), LV asynergy (6/29 cases, 21.7%) were detected. Pericarditis was detected in 7 patients (24.1%, LVD in 3 patients, LV asynergy in 2 patients) and 2 of them with subacute onset had progressive LV dysfunction, while 5 patients were normal in echocardiography after remission induction therapy for SLE. At the follow-up examination, LV dysfunction (9/29 cases, 31.0%, 5 new-onset and 1 improved case), LV asynergy (6/29 cases, 21.7%, 2 new-onset and 2 improved cases) were detected. Though any significant differences were observed between Group A and Group B at the baseline, platelet count (156.0 vs 207.0, p=0.049) were significantly lower in LV dysfunction group (Group A) at the follow-up examination. Group C patients had significantly higher uric acid (p=0.004), monocyte count (p=0.009), and MHR (p=0.003) than Group D(results in table).Conclusion:LV dysfunction is progressive in most of patients and requires regular follow-up once they developed. Uric acid, monocyte count and MHR are elevated in SLE patients with LV asynergy. Since MHR elevation was reported as useful marker of endothelial dysfunction5, our future goal is to analyse involvement of monocyte activation and endothelial dysfunction in LV asynergy of SLE patients.References:[1]Doria A et al. Lupus. 2005;14(9):683-6.[2]Manger K et al. Ann Rheum Dis. 2002 Dec;61(12):1065-70.[3]Leone P et al. Clin Exp Med. 2019 Dec 17.[4]Nagueh SF et al. J Am Soc Echocardiogr. 2016 Apr;29(4):277-314.[5]Acikgoz N et al. Angiology. 2018 Jan;69(1):65-70.Numbers are median (interquartile range), Mann-Whitney u test were performed, p value less than 0.05 was considered statistically significant.Disclosure of Interests: :None declared

scholarly journals Prophylactic temporary abdominal aortic balloon occlusion for patients with pernicious placenta previa: a retrospective study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fei Huo ◽  
Hansheng Liang ◽  
Yi Feng
Keyword(s):  
Placenta Previa ◽  
Balloon Occlusion ◽  
Artery Embolism ◽  
Abdominal Aortic ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Clinical Records ◽  
Group D ◽  
Central Placenta Previa

Abstract Background Pernicious placenta previa (PPP) can increase the risk of perioperative complications. During caesarean section in patients with adherent placenta, intraoperative blood loss, hysterectomy rate and transfusion could be reduced by interventional methods. Our study aimed to investigate the influence of maternal hemodynamics control and neonatal outcomes of prophylactic temporary abdominal aortic balloon (PTAAB) occlusion for patients with pernicious placenta previa. Methods This was a retrospective study using data from the Peking University People’s Hospital from January 2014 through January 2020. Clinical records of pregnant women undergoing cesarean section were collected. Patients were divided into two groups: treatment with PTAAB placement (group A) and no balloon placement (group B). Group A was further broken down into two groups: prophylactic placement (Group C) and balloon occlusion (group D). Results Clinical records of 33 cases from 5205 pregnant women underwent cesarean section were collected. The number of groups A, B, C, and D were 17, 16, 5 and 12.We found that a significant difference in the post-operative uterine artery embolism rates between group A and group B (0% vs.31.3%, p = 0.018). There was a significant difference in the Apgar scores at first minute between group A and group B (8.94 ± 1.43 vs 9.81 ± 0.75,p = 0.037),and the same significant difference between two groups in the pre-operative central placenta previa (29.4% vs. 0%,p = 0.044), complete placenta previa (58.8% vs 18.8%, p = 0.032),placenta implantation (76.5% vs 31.3%, p = 0.015). We could also observe the significant difference in the amount of blood cell (2.80 ± 2.68vs.10.66 ± 11.97, p = 0.038) and blood plasma transfusion (280.00 ± 268.32 vs. 1033.33 ± 1098.20, p = 0.044) between group C and group D. The significant differences in the preoperative vaginal bleeding conditions (0% vs 75%, p = 0.009), the intraoperative application rates of vasopressors (0% vs. 58.3%, p = 0.044) and the postoperative ICU (intensive care unit) admission rates (0% vs. 58.3%, p = 0.044) were also kept. Conclusions PTAAB occlusion could be useful in reducing the rate of post-operative uterine artery embolism and the amount of transfusion, and be useful in coping with patients with preoperative vaginal bleeding conditions, so as to reduce the rate of intraoperative applications of vasopressors and the postoperative ICU (intensive care unit) admission. In PPP patients with placenta implantation, central placenta previa and complete placenta previa, we advocate the utilization of prophylactic temporary abdominal aortic balloon placement.

scholarly journals Biomechanical study of Tile C3 pelvic fracture fixation using an anterior internal system combined with sacroiliac screws

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Lin Liu ◽  
Donggui Zeng ◽  
Shicai Fan ◽  
Yongxing Peng ◽  
Hui Song ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Steel Plate ◽  
Standing Position ◽  
Pelvic Fractures ◽  
Internal Fixator ◽  
Sacroiliac Joints ◽  
Sacroiliac Screws ◽  
Group A ◽  
Group B ◽  
Group D

Abstract Background How to perform minimally-invasive surgery on Tile C pelvic fractures is very difficult, and it is also a hot topic in orthopedic trauma research. We applied minimally-invasive treatment using an anterior internal fixator combined with sacroiliac screws. Objectives To compare the biomechanical properties of different fixation models in pelvic facture specimens, using an internal fixation system or a steel plate combined with sacroiliac screws. Methods Sixteen fresh adult cadaver pelvic specimens were randomly separated into four groups named A, B, C, and D. The four groups were respectively stabilized using a two-screwed, three-screwed, or four-screwed anterior internal fixator or a steel plate with sacroiliac screws. All models were tested in both standing and sitting positions. Vertical loads of 600 N were applied increasingly. Shifts of bilateral sacroiliac joints and pubis rupture were measured. Results The shifts in sacroiliac joints and pubis rupture in the standing position were all less than 3.5 mm, and the shifts in the sitting position were all less than 1 mm. In the standing position, the results of shifts in the sacroiliac joints were group C < group D < group B < group A. For comparisons between A:B and C:D, P > 0.05. For comparisons between A, B:C, and D, P < 0.05. The results of shifts in pubis ruptures were group D < group C < group B < group A. In the comparison between C:D, P > 0.05; for comparisons between A:B, A:C, A:D, B:C, and B:D, P < 0.05. In the sitting posture, the results of shifts in the sacroiliac joints were group C < group D < group B < group A, and the shifts in the pubis ruptures were group D < group C < roup B < group A. For comparison between C:D, P > 0.05. For comparisons between A:B, A:C, A:D, B:C, and B:D, P < 0.05. Conclusion Use of an anterior internal fixator combined with sacroiliac screws effectively stabilized Tile C3 pelvic fractures. The stability of specimens increased as the number of screws in the internal fixator increased.

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