scholarly journals Nanoplasmonic Structure of a Polycarbonate Substrate Integrated with Parallel Microchannels for Label-Free Multiplex Detection

Polymers ◽  
2021 ◽  
Vol 13 (19) ◽  
pp. 3294
Author(s):  
Yi-Jung Lu ◽  
Han-Yun Hsieh ◽  
Wen-Chang Kuo ◽  
Pei-Kuen Wei ◽  
Horn-Jiunn Sheen ◽  
...  
Keyword(s):  
Detection System ◽  
Localized Surface Plasmon ◽  
Oxygen Plasma Treatment ◽  
Microfluidic Channels ◽  
Light Illumination ◽  
Label Free ◽  
Multiplex Detection ◽  
Parallel Microchannels ◽  
Polycarbonate Substrate ◽  
White Light Illumination

In this study, a multiplex detection system was proposed by integrating a localized surface plasmon resonance (LSPR) sensing array and parallel microfluidic channels. The LSPR sensing array was fabricated by nanoimprinting and gold sputter on a polycarbonate (PC) substrate. The polydimethylsiloxane (PDMS) microfluidic channels and PC LSPR sensing array were bound together through (3-aminopropyl)triethoxysilane (APTES) surface treatment and oxygen plasma treatment. The resonant spectrum of the LSPR sensing device was obtained by broadband white-light illumination and polarized wavelength measurements with a spectrometer. The sensitivity of the LSPR sensing device was measured using various ratios of glycerol to water solutions with different refractive indices. Multiplex detection was demonstrated using human immunoglobulin G (IgG), IgA, and IgM. The anti-IgG, anti-IgA, and anti-IgM were separately modified in each sensing region. Various concentrations of human IgG, IgA, and IgM were prepared to prove the concept that the parallel sensing device can be used to detect different targets.

Investigating the fluid dynamics of rapid processes within microfluidic devices using bright-field microscopy

Lab on a Chip ◽  
2015 ◽  
Vol 15 (9) ◽  
pp. 2140-2144 ◽  
Author(s):  
Tohid Pirbodaghi ◽  
Daniele Vigolo ◽  
Samin Akbari ◽  
Andrew deMello
Keyword(s):  
Fluid Dynamics ◽  
White Light ◽  
Experimental Approach ◽  
Microfluidic Devices ◽  
Microfluidic Channels ◽  
Light Illumination ◽  
Bright Field ◽  
Bright Field Microscopy ◽  
White Light Illumination

To better understanding fluid dynamics within microfluidic channels, herein, we present an accurate experimental approach for studying the fluid dynamics of rapid processes within microfluidic devices using bright-field microscopy with white light illumination.

scholarly journals Rapid real-time recirculating PCR using localized surface plasmon resonance (LSPR) and piezo-electric pumping

Lab on a Chip ◽  
2017 ◽  
Vol 17 (16) ◽  
pp. 2821-2830 ◽  
Author(s):  
J. M. Haber ◽  
P. R. C. Gascoyne ◽  
K. Sokolov
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Localized Surface Plasmon Resonance ◽  
Pathogen Detection ◽  
Microfluidic System ◽  
Localized Surface Plasmon ◽  
Label Free ◽  
Multiplex Detection ◽  
Highly Sensitive ◽  
On Chip

The paper describes a novel on-chip microfluidic system for rapid highly sensitive and label-free multiplex detection of DNA molecules with specific focus on pathogen detection.

Effect of Illumination on Organic Polymer Thin-Film Transistors

2003 ◽  
Vol 771 ◽  
Author(s):  
Michael C. Hamilton ◽  
Sandrine Martin ◽  
Jerzy Kanicki
Keyword(s):  
Thin Film ◽  
Thin Film Transistors ◽  
Drain Current ◽  
Charge Carriers ◽  
Electrical Performance ◽  
Organic Polymer ◽  
Light Illumination ◽  
Polymer Thin Film ◽  
Channel Region ◽  
White Light Illumination

AbstractWe have investigated the effects of white-light illumination on the electrical performance of organic polymer thin-film transistors (OP-TFTs). The OFF-state drain current is significantly increased, while the drain current in the strong accumulation regime is relatively unaffected. At the same time, the threshold voltage is decreased and the subthreshold slope is increased, while the field-effect mobility of the charge carriers is not affected. The observed effects are explained in terms of the photogeneration of free charge carriers in the channel region due to the absorbed photons.

Plasma enhanced label-free immunoassay for alpha-fetoprotein based on a U-bend fiber-optic LSPR biosensor

RSC Advances ◽  
2015 ◽  
Vol 5 (31) ◽  
pp. 23990-23998 ◽  
Author(s):  
Gaoling Liang ◽  
Zhongjun Zhao ◽  
Yin Wei ◽  
Kunping Liu ◽  
Wenqian Hou ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Localized Surface Plasmon Resonance ◽  
Fiber Optic ◽  
Cost Effective ◽  
Alpha Fetoprotein ◽  
Localized Surface Plasmon ◽  
Label Free

A simple, label-free and cost-effective localized surface plasmon resonance (LSPR) immunosensing method was developed for detection of alpha-fetoprotein (AFP).

scholarly journals Advanced Label-Free Laser Scanning Microscopy and Its Biological Imaging Application

2021 ◽  
Vol 11 (3) ◽  
pp. 1002
Author(s):  
Xue Wang ◽  
Xinchao Lu ◽  
Chengjun Huang
Keyword(s):  
Laser Scanning ◽  
Second Harmonic ◽  
Biological Tissues ◽  
Biological Imaging ◽  
Laser Scanning Microscopy ◽  
Scanning Microscopy ◽  
Localized Surface Plasmon ◽  
Label Free ◽  
Coherent Raman ◽  
Surface Plasmon Microscopy

By eliminating the photodamage and photobleaching induced by high intensity laser and fluorescent molecular, the label-free laser scanning microscopy shows powerful capability for imaging and dynamic tracing to biological tissues and cells. In this review, three types of label-free laser scanning microscopies: laser scanning coherent Raman scattering microscopy, second harmonic generation microscopy and scanning localized surface plasmon microscopy are discussed with their fundamentals, features and recent progress. The applications of label-free biological imaging of these laser scanning microscopies are also introduced. Finally, the performance of the microscopies is compared and the limitation and perspectives are summarized.

Full field of view super-resolution imaging based on two static gratings and white light illumination

2008 ◽  
Vol 47 (17) ◽  
pp. 3080 ◽  
Author(s):  
Javier García ◽  
Vicente Micó ◽  
Dan Cojoc ◽  
Zeev Zalevsky
Keyword(s):  
White Light ◽  
Super Resolution ◽  
Field Of View ◽  
Light Illumination ◽  
Full Field ◽  
Resolution Imaging ◽  
White Light Illumination

scholarly journals Tuning the Surface Wettability of Cyclic Olefin Copolymer by Plasma Treatment and Graphene Oxide Deposition and Reduction

Polymers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 2305
Author(s):  
Fadi Dawaymeh ◽  
Yawar Abbas ◽  
Maryam Khaleel ◽  
Anas Alazzam ◽  
Nahla Alamoodi
Keyword(s):  
Contact Angle ◽  
Plasma Treatment ◽  
Treatment Duration ◽  
Chemical Reduction ◽  
Surface Wettability ◽  
Oxygen Plasma Treatment ◽  
Microfluidic Channels ◽  
Cyclic Olefin Copolymer ◽  
Cyclic Olefin ◽  
Reduction Methods

Selective altering of surface wettability in microfluidic channels provides a suitable platform for a large range of processes, such as the phase separation of multiphase systems, synthesis of reaction controlled, nanoliter sized droplet reactors, and catalyst impregnation. Herein we study the feasibility to tune the wettability of a flexible cyclic olefin copolymer (COC). Two methods were considered for enhancing the surface hydrophilicity. The first is argon/oxygen plasma treatment, where the effect of treatment duration on water contact angle and COC surface morphology and chemistry were investigated, and the second is coating COC with GO dispersions of different concentrations. For enhancing the hydrophobicity of GO-coated COC surfaces, three reduction methods were considered: chemical reduction by Hydroiodic acid (HI), thermal reduction, and photo reduction by exposure of GO-coated COC to UV light. The results show that as the GO concentration and plasma treatment duration increased, a significant decrease in contact angle was observed, which confirmed the ability to enhance the wettability of the COC surface. The increase in hydrophilicity during plasma treatment was associated with the increase in surface roughness on the treated surfaces, while the increase during GO coating was associated with introducing oxygen-containing groups on the GO-coated COC surfaces. The results also show that the different reduction methods considered can increase the contact angle and improve the hydrophobicity of a GO-coated COC surface. It was found that the significant improvement in hydrophobicity was related to the reduction of oxygen-containing groups on the GO-coated COC modified surface.

Mesh size control in forming an Ag/AgO nano-network structure for transparent conducting application

2021 ◽  
Author(s):  
Jia-Wei Chen ◽  
Shaobo Yang ◽  
Chia-Hao Li ◽  
Yang-Yi Huang ◽  
Chen-Hua Chen ◽  
...  
Keyword(s):  
Sheet Resistance ◽  
Thermal Annealing ◽  
Mesh Size ◽  
Localized Surface Plasmon ◽  
Light Illumination ◽  
Transparent Conductor ◽  
Large Area ◽  
Ag Nps ◽  
Resistance Level ◽  
Ag Deposition

Abstract The variation behaviors of the morphology, transmission, and sheet resistance of the surface Ag/AgO nano-network (NNW) structures fabricated under different illumination conditions and with different Ag deposition thicknesses and thermal annealing temperatures in forming initial Ag nanoparticles (NPs) are studied. Generally, an NNW structure with a smaller mesh size or a denser branch distribution has a lower transmission and a lower sheet resistance level. Under the fabrication condition of a broader illumination spectrum, a lower thermal annealing temperature, or a thicker Ag deposition, we can obtain an NNW structure of a smaller mesh size. The mesh size of an NNW structure is basically controlled by the seed density of Brownian tree (BT) at the beginning of light illumination. A BT-seed can be formed through a stronger local localized surface plasmon resonance for accelerating Ag oxidation in a certain region. Once an Ag/AgO BT-seed is formed, the surrounding Ag NPs are reorganized to form the branches of a BT. Multiple BTs are connected to form a large-area NNW structure, which can serve as a transparent conductor. Under the fabrication conditions of a broader illumination spectrum, 3-nm Ag deposition, and 100-degree-C thermal annealing, we can implement an NNW structure to achieve ~1.15 micron in mesh size, ~90 Ohm/sq in sheet resistance, and 93-77 % in transmittance within the wavelength range between 370 and 700 nm.

The chiral coating on an achiral nanostructure by the secondary effect in focused ion beam induced deposition

2021 ◽  
Author(s):  
Chen Fang ◽  
Qing Chai ◽  
Ye Chen ◽  
Yan Xing ◽  
Zai-fa Zhou
Keyword(s):  
Circular Dichroism ◽  
Focused Ion Beam ◽  
Ion Beam ◽  
Polarized Light ◽  
Localized Surface Plasmon ◽  
Light Illumination ◽  
Secondary Effect ◽  
Circularly Polarized Light ◽  
Optical Metamaterials ◽  
Circular Dichroïsm

Abstract Optical metamaterials are widely used in electromagnetic wave modulation due to their sub-wavelength feature sizes. In this paper, a method to plate an achiral nanopillar array with chiral coating by the secondary effect in focused ion beam induced deposition is proposed. Guided by the pattern defined in a bitmap with variable residence time, the beam scan strategy suppresses the interaction between adjacent nanostructures. A uniform chiral coating is formed on the target nanostructure without affecting the adjacent nanostructure, under carefully selected beam parameters and the rotation angle of the sample stage. Energy Dispersive X-Ray Spectroscopy results show that the chiral film has high purity metal, which enables the generation of localized surface plasmon resonances and causes the circular dichroism under circularly polarized light illumination. Finally, the tailorable circular dichroism spectrum of the coated array is verified by the Finite Difference Time Domain method.

Sign in / Sign up

Export Citation Format

Share Document