scholarly journals Radiometric Scale Transfer Using Bayesian Model Selection

Proceedings ◽  
2020 ◽  
Vol 33 (1) ◽  
pp. 32
Author(s):  
Donald W. Nelson ◽  
Udo von Toussaint
Keyword(s):  
Model Selection ◽  
Ground Truth ◽  
Climate Modelling ◽  
Input Quantity ◽  
Weather Forecasts ◽  
Alternative Approach ◽  
Wide Range ◽  
Regression Functions ◽  
Approach Method ◽  
Selection Of

The key input quantity to climate modelling and weather forecasts is the solar beam irradiance, i.e., the primary amount of energy provided by the sun. Despite its importance the absolute accuracy of the measurements are limited—which not only affects the modelling but also ground truth tests of satellite observations. Here we focus on the problem of improving instrument calibration based on dedicated measurements. A Bayesian approach reveals that the standard approach results in inferior results. An alternative approach method based on monomial based selection of regression functions, combined with model selection is shown to yield superior estimations for a wide range of conditions. The approach is illustrated on selected data and possible further enhancements are outlined.

A snippet in a snippet: Development of the Matryoshka principle for the construction of very short musical stimuli (plinks)

2019 ◽  
Vol 24 (4) ◽  
pp. 515-529 ◽  
Author(s):  
Felix Christian Thiesen ◽  
Reinhard Kopiez ◽  
Christoph Reuter ◽  
Isabella Czedik-Eysenberg
Keyword(s):  
Strong Evidence ◽  
Extraction Procedure ◽  
Recognition Task ◽  
Acoustic Parameters ◽  
The Past ◽  
Popular Songs ◽  
Alternative Approach ◽  
Wide Range ◽  
Stimulus Generation ◽  
Selection Of

For the past 140 years, numerous studies have been conducted to examine minimum durations of samples needed for the recognition of acoustic parameters such as pitch, timbre or vocal phonemes. Recent studies in this field are often based on short clips (plinks) of popular songs, using target variables such as titles and interpreters. These studies provide strong evidence that a wide range of intra- and extramusical information can be identified above chance level for stimuli lasting much shorter than a second. Nevertheless, a review of precedent studies revealed a heterogeneity in stimulus generation processes that could have influenced overall recognition rates. As a piece of music unfolds in time, its timbral structure is subject to a variety of changes. We assume that the position of stimulus extraction, therefore, could influence the outcomes of a subsequent recognition task, for instance. In this study, we offer a systematic and objective stimulus extraction procedure that might help to control for (a) a possible confounding of stimulus duration and timbre (caused by the extraction of stimulus sets of various length from different song positions), (b) possible confoundings of song section and timbre (caused by the comparison of stimulus sets from divergent song sections), and (c) the suspected influence of subjective criteria on extract selection (caused by the non-randomized selection of extract positions). As an alternative approach, the suggested Matryoshka principle produces randomized sets of nested stimuli controlled for song position and objective selection. Each set represents an individual section and consists of five short excerpts, cut from each other in decreasing duration. Correlation analyses confirmed that these sets prove to be stable in terms of their mel-frequency cepstrum coefficients, the so-called “psycho-acoustic fingerprint” of a sound. Based on the software Random Plink Generator, the suggested procedure can help to contribute to an objective selection of stimuli in future plink research.

COMBINATORIAL POLYNOMIALLY COMPUTABLE CHARACTERISTICS OF SUBSTITUTIONS AND THEIR PROPERTIES

2020 ◽  
Vol 7 (2) ◽  
pp. 34-41
Author(s):  
VLADIMIR NIKONOV ◽  
◽  
ANTON ZOBOV ◽  
Keyword(s):  
Mathematical Expectation ◽  
Point Of View ◽  
Small Range ◽  
Computational Point ◽  
Wide Range ◽  
Bijective Function ◽  
The Difference ◽  
Element Base ◽  
Selection Of

The construction and selection of a suitable bijective function, that is, substitution, is now becoming an important applied task, particularly for building block encryption systems. Many articles have suggested using different approaches to determining the quality of substitution, but most of them are highly computationally complex. The solution of this problem will significantly expand the range of methods for constructing and analyzing scheme in information protection systems. The purpose of research is to find easily measurable characteristics of substitutions, allowing to evaluate their quality, and also measures of the proximity of a particular substitutions to a random one, or its distance from it. For this purpose, several characteristics were proposed in this work: difference and polynomial, and their mathematical expectation was found, as well as variance for the difference characteristic. This allows us to make a conclusion about its quality by comparing the result of calculating the characteristic for a particular substitution with the calculated mathematical expectation. From a computational point of view, the thesises of the article are of exceptional interest due to the simplicity of the algorithm for quantifying the quality of bijective function substitutions. By its nature, the operation of calculating the difference characteristic carries out a simple summation of integer terms in a fixed and small range. Such an operation, both in the modern and in the prospective element base, is embedded in the logic of a wide range of functional elements, especially when implementing computational actions in the optical range, or on other carriers related to the field of nanotechnology.

Implementasi Algoritma MAX-MIN Ant System pada Penjadwalan Mata Kuliah

2013 ◽  
Vol 5 (2) ◽  
pp. 48-53
Author(s):  
William Aprilius ◽  
Lorentzo Augustino ◽  
Ong Yeremia M. H.
Keyword(s):  
Ant Colony Optimization ◽  
Ant Colony ◽  
Ant System ◽  
University Course Timetabling ◽  
Alternative Approach ◽  
Ant System Algorithm ◽  
Index Terms ◽  
Course Timetabling Problem ◽  
University Course ◽  
Selection Of

University Course Timetabling Problem is a problem faced by every university, one of which is Universitas Multimedia Nusantara. Timetabling process is done by allocating time and space so that the whole associated class and course can be implemented. In this paper, the problem will be solved by using MAX-MIN Ant System Algorithm. This algorithm is an alternative approach to ant colony optimization. This algorithm uses two tables of pheromones as stigmergy, i.e. timeslot pheromone table and room pheromone table. In addition, the selection of timeslot and room is done by using the standard deviation of the value of pheromones. Testing is carried out by using 105 events, 45 timeslots, and 3 types of categories based on the number of rooms provided, i.e. large, medium, and small. In each category, testing is performed 5 times and for each testing, the data recorded is the unplace and Soft Constraint Penalty. In general, the greater the number of rooms, the smaller the unplace. Index Terms—ant colony optimization, max-min ant system, timetabling

Synthesis, Characterization and Antiproliferative Activity Assessment of a Novel 1H-5-mercapto-1,2,4 Triazole Derivative

2017 ◽  
Vol 68 (4) ◽  
pp. 745-747 ◽  
Author(s):  
Marius Mioc ◽  
Sorin Avram ◽  
Vasile Bercean ◽  
Mihaela Balan Porcarasu ◽  
Codruta Soica ◽  
...  
Keyword(s):  
Antiproliferative Activity ◽  
Biological Activities ◽  
Cancer Cell Line ◽  
Vascular Endothelial ◽  
Triazole Derivative ◽  
Activity Assessment ◽  
Wide Range ◽  
Specific Receptors ◽  
Endothelial Growth Factor ◽  
Selection Of

Angiogenesis plays an important function in tumor proliferation, one of the main angiogenic promoters being the vascular endothelial growth factor (VEGF) which activates specific receptors, particularly VEGFR-2. Thus, VEGFR-2 has become an essential therapeutic target in the development of new antitumor drugs. 1,2,4-triazoles show a wide range of biological activities, including antitumor effect, which was documented by numerous reports. In the current study the selection of 5-mercapto-1,2,4-triazole structure (1H-3-styryl-5-benzylidenehydrazino-carbonyl-methylsulfanil-1,2,4-triazole, Tz3a.7) was conducted based on molecular docking that emphasized it as suitable ligand for VEGFR-2 and EGFR1 receptors. Compound Tz3a.7 was synthesized and physicochemically and biologically evaluated thus revealing a moderate antiproliferative activity against breast cancer cell line MDA-MB-231.

Effect of Contact Ratio on Spur Gear Dynamic Load With No Tooth Profile Modifications

1996 ◽  
Vol 118 (3) ◽  
pp. 439-443 ◽  
Author(s):  
Chuen-Huei Liou ◽  
Hsiang Hsi Lin ◽  
F. B. Oswald ◽  
D. P. Townsend
Keyword(s):  
Dynamic Load ◽  
Spur Gear ◽  
Tooth Size ◽  
Contact Ratio ◽  
Gear Dynamics ◽  
Wide Range ◽  
Gear Contact ◽  
Center Distance ◽  
Selection Of ◽  
Better Than

This paper presents a computer simulation showing how the gear contact ratio affects the dynamic load on a spur gear transmission. The contact ratio can be affected by the tooth addendum, the pressure angle, the tooth size (diametral pitch), and the center distance. The analysis presented in this paper was performed by using the NASA gear dynamics code DANST. In the analysis, the contact ratio was varied over the range 1.20 to 2.40 by changing the length of the tooth addendum. In order to simplify the analysis, other parameters related to contact ratio were held constant. The contact ratio was found to have a significant influence on gear dynamics. Over a wide range of operating speeds, a contact ratio close to 2.0 minimized dynamic load. For low-contact-ratio gears (contact ratio less than two), increasing the contact ratio reduced gear dynamic load. For high-contact-ratio gears (contact ratio equal to or greater than 2.0), the selection of contact ratio should take into consideration the intended operating speeds. In general, high-contact-ratio gears minimized dynamic load better than low-contact-ratio gears.

scholarly journals A Virtual Telescope for the Open University Science Foundation Course

1998 ◽  
Vol 162 ◽  
pp. 100-105
Author(s):  
Andrew J. Norton ◽  
Mark H. Jones
Keyword(s):  
Social Science ◽  
Open University ◽  
Distance Teaching ◽  
The Arts ◽  
Wide Range ◽  
University Science ◽  
First Time ◽  
Degree Level ◽  
Selection Of

The Open University is the UK's foremost distance teaching university. For over twenty five years we have been presenting courses to students spanning a wide range of degree level and vocational subjects. Since we have no pre-requisites for entry, a major component of our course profile is a selection of foundation courses comprising one each in the Arts, Social Science, Mathematics, Technology and Science faculties. The Science Faculty's foundation course is currently undergoing a substantial revision. The new course, entitled “S103: Discovering Science”, will be presented to students for the first time in 1998.

scholarly journals Organelle Genetics in Plants

2021 ◽  
Vol 22 (4) ◽  
pp. 2104
Author(s):  
Pedro Robles ◽  
Víctor Quesada
Keyword(s):  
Rna Editing ◽  
Posttranscriptional Regulation ◽  
Genome Engineering ◽  
Plant Mitochondria ◽  
Plastid Dna ◽  
Chloroplast Genomes ◽  
Wide Range ◽  
Organelle Genetics ◽  
Selection Of

Eleven published articles (4 reviews, 7 research papers) are collected in the Special Issue entitled “Organelle Genetics in Plants.” This selection of papers covers a wide range of topics related to chloroplasts and plant mitochondria research: (i) organellar gene expression (OGE) and, more specifically, chloroplast RNA editing in soybean, mitochondria RNA editing, and intron splicing in soybean during nodulation, as well as the study of the roles of transcriptional and posttranscriptional regulation of OGE in plant adaptation to environmental stress; (ii) analysis of the nuclear integrants of mitochondrial DNA (NUMTs) or plastid DNA (NUPTs); (iii) sequencing and characterization of mitochondrial and chloroplast genomes; (iv) recent advances in plastid genome engineering. Here we summarize the main findings of these works, which represent the latest research on the genetics, genomics, and biotechnology of chloroplasts and mitochondria.

scholarly journals BonMOLière: Small-Sized Libraries of Readily Purchasable Compounds, Optimized to Produce Genuine Hits in Biological Screens across the Protein Space

2021 ◽  
Vol 22 (15) ◽  
pp. 7773
Author(s):  
Neann Mathai ◽  
Conrad Stork ◽  
Johannes Kirchmair
Keyword(s):  
Large Scale ◽  
Computational Approach ◽  
Large Sets ◽  
Compound Libraries ◽  
Wide Range ◽  
Protein Space ◽  
High Chance ◽  
Large Scale Screening ◽  
Early Drug ◽  
Selection Of

Experimental screening of large sets of compounds against macromolecular targets is a key strategy to identify novel bioactivities. However, large-scale screening requires substantial experimental resources and is time-consuming and challenging. Therefore, small to medium-sized compound libraries with a high chance of producing genuine hits on an arbitrary protein of interest would be of great value to fields related to early drug discovery, in particular biochemical and cell research. Here, we present a computational approach that incorporates drug-likeness, predicted bioactivities, biological space coverage, and target novelty, to generate optimized compound libraries with maximized chances of producing genuine hits for a wide range of proteins. The computational approach evaluates drug-likeness with a set of established rules, predicts bioactivities with a validated, similarity-based approach, and optimizes the composition of small sets of compounds towards maximum target coverage and novelty. We found that, in comparison to the random selection of compounds for a library, our approach generates substantially improved compound sets. Quantified as the “fitness” of compound libraries, the calculated improvements ranged from +60% (for a library of 15,000 compounds) to +184% (for a library of 1000 compounds). The best of the optimized compound libraries prepared in this work are available for download as a dataset bundle (“BonMOLière”).

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