scholarly journals Sensitive and Reproducible Gold SERS Sensor Based on Interference Lithography and Electrophoretic Deposition

Sensors ◽  
2018 ◽  
Vol 18 (11) ◽  
pp. 4076 ◽  
Author(s):  
June Hwang ◽  
Minyang Yang
Keyword(s):  
Gold Nanoparticle ◽  
Electrophoretic Deposition ◽  
Large Scale ◽  
Surface Enhanced Raman Spectroscopy ◽  
Localized Surface Plasmon ◽  
Interference Lithography ◽  
Metal Nanostructures ◽  
Nanoparticle Array ◽  
Laser Ablation In Liquid ◽  
Label Free Detection

Surface-enhanced Raman spectroscopy (SERS) is a promising analytical tool due to its label-free detection ability and superior sensitivity, which enable the detection of single molecules. Since its sensitivity is highly dependent on localized surface plasmon resonance, various methods have been applied for electric field-enhanced metal nanostructures. Despite the intensive research on practical applications of SERS, fabricating a sensitive and reproducible SERS sensor using a simple and low-cost process remains a challenge. Here, we report a simple strategy to produce a large-scale gold nanoparticle array based on laser interference lithography and the electrophoretic deposition of gold nanoparticles, generated through a pulsed laser ablation in liquid process. The fabricated gold nanoparticle array produced a sensitive, reproducible SERS signal, which allowed Rhodamine 6G to be detected at a concentration as low as 10−8 M, with an enhancement factor of 1.25 × 105. This advantageous fabrication strategy is expected to enable practical SERS applications.

scholarly journals Composite Structure Based on Gold-Nanoparticle Layer and HMM for Surface-Enhanced Raman Spectroscopy Analysis

Nanomaterials ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 587
Author(s):  
Zirui Wang ◽  
Yanyan Huo ◽  
Tingyin Ning ◽  
Runcheng Liu ◽  
Zhipeng Zha ◽  
...  
Keyword(s):  
Gold Nanoparticle ◽  
Surface Plasmon ◽  
Composite Structure ◽  
Surface Enhanced Raman Spectroscopy ◽  
Localized Surface Plasmon ◽  
Sers Substrate ◽  
Nanoparticle Layer ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Plasmon Polaritons

Hyperbolic metamaterials (HMMs), supporting surface plasmon polaritons (SPPs), and highly confined bulk plasmon polaritons (BPPs) possess promising potential for application as surface-enhanced Raman scattering (SERS) substrates. In the present study, a composite SERS substrate based on a multilayer HMM and gold-nanoparticle (Au-NP) layer was fabricated. A strong electromagnetic field was generated at the nanogaps of the Au NPs under the coupling between localized surface plasmon resonance (LSPR) and a BPP. Additionally, a simulation of the composite structure was assessed using COMSOL; the results complied with those achieved through experiments: the SERS performance was enhanced, while the enhancing rate was downregulated, with the extension of the HMM periods. Furthermore, this structure exhibited high detection performance. During the experiments, rhodamine 6G (R6G) and malachite green (MG) acted as the probe molecules, and the limits of detection of the SERS substrate reached 10−10 and 10−8 M for R6G and MG, respectively. Moreover, the composite structure demonstrated prominent reproducibility and stability. The mentioned promising results reveal that the composite structure could have extensive applications, such as in biosensors and food safety inspection.

scholarly journals Detection of Biomarkers Using LSPR Substrate with Gold Nanoparticle Array

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Young Min Bae ◽  
Seung Oh Jin ◽  
Insoo Kim ◽  
Ki Young Shin ◽  
Duchang Heo ◽  
...  
Keyword(s):  
Gold Nanoparticle ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Nanoparticle Array ◽  
Label Free ◽  
Short Analysis Time ◽  
Label Free Detection ◽  
Lift Off ◽  
Detection Of Biomarkers ◽  
The Cost

In the biosensing platform, label-free detection technique provides advantages such as the short analysis time and the cost-effectiveness. In this study, we showed the feasibility of the LSPR substrate with gold nanoparticle array for detecting low density lipoprotein (LDL) and high density lipoprotein (HDL) without labeling. The LSPR substrate was fabricated through the lift-off process with the anodized alumina mask, and its LSPR phenomenon was observed by measuring the optical transmission of substrate. The antibodies were immobilized on the gold nanoparticle array via the chemical binding, in which the 11-MUA was used as the linker to bind the antibodies. The binding of antibodies was confirmed by observing the shift of LSPR peak of the substrate. Finally, with the LSPR substrates with the antibodies immobilized, the detection of LDL and HDL was investigated. As a result, LDL and HDL could be detected in the clinically available concentration range, respectively.

SERS-Modeling in Molecular Sensing

2015 ◽  
Vol 1109 ◽  
pp. 223-226
Author(s):  
Asing ◽  
Md Eaqub Ali ◽  
Sharifah Bee Abd Hamid
Keyword(s):  
Limit Of Detection ◽  
Specific Binding ◽  
Signal Strength ◽  
Metal Structure ◽  
Surface Enhanced Raman Spectroscopy ◽  
Interparticle Spacing ◽  
Localized Surface Plasmon ◽  
Metal Nanostructures ◽  
Plasmonic Nanostructures ◽  
Molecular Sensing

Surface enhanced Raman spectroscopy (SERS) is an ultrasensitive vibrational spectroscopic technique that useful tools in detecting biomolecules at near or on the surface of plasmonic nanostructures. Unique physicochemical and optical properties of noble metal nanostructures allow the assimilation of biomolecular probes and exhibit distinctive spectra, prompting the development of a plethora of biosensing platforms in molecular diagnostics. In SERS biosensor, signal to noise ration such as recognition and transducer elements that provide fingerprint spectrum at the lower limit of detection with specific binding or hybridized event, increasing reliability and sensitivity. Since the localized surface plasmon resonance (LSPR) of nanoparticle lies at the heart of SERS. It is essential to control all of the LSPR influencing factors in highly sensitivity signal strength that ensures reproducibility of SERS signals. SERS active substrates, transducer elements, metal surfaces modification, interparticle spacing, dielectric environment and selection of biorecognition molecules contribute in SERS signal strength. Modified metal structure with bioprobe and Raman reporter molecules provides a strong signature fingerprints that surely contribute to noble biosensor structural designing. We reviewed here ideal fabrication of nanostructure for SERS application in molecular sensing research fields.

Fabrication and Applications of Long-Range Ordered Au Nanodisk Arrays

2008 ◽  
Author(s):  
Yue Bing Zheng ◽  
Bala Krishna Juluri ◽  
Tony Jun Huang
Keyword(s):  
Long Range ◽  
Large Scale ◽  
Focused Ion Beam ◽  
Low Cost ◽  
Ion Beam ◽  
Spatial Coherence ◽  
Surface Enhanced Raman Spectroscopy ◽  
Microfluidic System ◽  
Localized Surface Plasmon ◽  
Microfluidic Channels

Large-scale nanostructure arrays with spatial coherence are useful for many applications. Conventional nanofabrication techniques such as electron beam lithography and focused ion beam lithography are expensive and time-consuming. In this paper, long-range ordered Au nanodisk arrays were fabricated on glass substrates using nanosphere lithography (NSL) combined with reactive ion etching (RIE) techniques. The morphology and size distribution of the Au nanodisks were examined with scanning electron microscopy (SEM) and atomic force microscopy (AFM). The sensitivity of the localized surface plasmon resonance (LSPR) of the Au nanodisk arrays to change in the surroundings’ refractive index was evaluated by integrating the Au nanodisk arrays into microfluidic channels. The measured sensitivity was supported by discrete dipole approximation (DDA) calculations. Further, we designed and fabricated an all-optical plasmonic switch based on the Au nanodisk arrays and photoresponsive liquid crystals (LCs). The high-quality optical properties and high-degree spatial uniformity of the nanodisk arrays, together with simple, low-cost fabrication and easy integration with microfluidic system, suggest tremendous potential in using these nanostructures in many other applications, including biosensing and imaging, surface-enhanced Raman spectroscopy (SERS), and plasmonic tweezers.

scholarly journals Synthesis and Deposition of Ag Nanoparticles by Combining Laser Ablation and Electrophoretic Deposition Techniques

Coatings ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. 571 ◽  
Author(s):  
Fernández-Arias ◽  
Zimbone ◽  
Boutinguiza ◽  
Val ◽  
Riveiro ◽  
...  
Keyword(s):  
Laser Ablation ◽  
Electrophoretic Deposition ◽  
Ag Nanoparticles ◽  
Localized Surface Plasmon ◽  
X Ray Diffraction ◽  
Laser Ablation In Liquid ◽  
X Ray ◽  
Transmission Electron ◽  
Uv Visible ◽  
Deposition Techniques

Silver nanostructured thin films have been fabricated on silicon substrate by combining simultaneously pulsed laser ablation in liquid (PLAL) and electrophoretic deposition (ED) techniques. The composition, topography, crystalline structure, surface topography, and optical properties of the obtained films have been studied by energy dispersive X-ray spectroscopy (EDS), high-resolution transmission electron microscopy (HRTEM), X-ray diffraction (XRD), and UV-visible spectrophotometry. The coatings were composed of Ag nanoparticles ranging from a few to hundred nm. The films exhibited homogenous morphology, uniform appearance, and a clear localized surface plasmon resonance (LSPR) around 400 nm.

scholarly journals Hollow metal nanostructures for enhanced plasmonics: synthesis, local plasmonic properties and applications

Nanophotonics ◽  
2017 ◽  
Vol 6 (1) ◽  
pp. 193-213 ◽  
Author(s):  
Aziz Genç ◽  
Javier Patarroyo ◽  
Jordi Sancho-Parramon ◽  
Neus G. Bastús ◽  
Victor Puntes ◽  
...  
Keyword(s):  
Surface Plasmon ◽  
Building Blocks ◽  
Surface Enhanced Raman Spectroscopy ◽  
Localized Surface Plasmon ◽  
Cancer Drug ◽  
Homogeneous Distribution ◽  
Metal Nanostructures ◽  
Galvanic Replacement ◽  
Hollow Nanostructures ◽  
Hollow Metal

AbstractMetallic nanostructures have received great attention due to their ability to generate surface plasmon resonances, which are collective oscillations of conduction electrons of a material excited by an electromagnetic wave. Plasmonic metal nanostructures are able to localize and manipulate the light at the nanoscale and, therefore, are attractive building blocks for various emerging applications. In particular, hollow nanostructures are promising plasmonic materials as cavities are known to have better plasmonic properties than their solid counterparts thanks to the plasmon hybridization mechanism. The hybridization of the plasmons results in the enhancement of the plasmon fields along with more homogeneous distribution as well as the reduction of localized surface plasmon resonance (LSPR) quenching due to absorption. In this review, we summarize the efforts on the synthesis of hollow metal nanostructures with an emphasis on the galvanic replacement reaction. In the second part of this review, we discuss the advancements on the characterization of plasmonic properties of hollow nanostructures, covering the single nanoparticle experiments, nanoscale characterization via electron energy-loss spectroscopy and modeling and simulation studies. Examples of the applications, i.e. sensing, surface enhanced Raman spectroscopy, photothermal ablation therapy of cancer, drug delivery or catalysis among others, where hollow nanostructures perform better than their solid counterparts, are also evaluated.

scholarly journals Noble Metal Nanostructures Influence of Structure and Environment on Their Optical Properties

2013 ◽  
Vol 2013 ◽  
pp. 1-15 ◽  
Author(s):  
Ondřej Kvítek ◽  
Jakub Siegel ◽  
Vladimír Hnatowicz ◽  
Václav Švorčík
Keyword(s):  
Optical Properties ◽  
Surface Plasmons ◽  
Noble Metal ◽  
Plasmon Resonance ◽  
Large Scale ◽  
Surface Enhanced Raman Spectroscopy ◽  
Metal Nanostructures ◽  
Label Free ◽  
Surface Enhanced Raman ◽  
Noble Metal Nanostructures

Optical properties of nanostructured materials, isolated nanoparticles, and structures composed of both metals and semiconductors are broadly discussed. Fundamentals of the origin of surface plasmons as well as the surface plasmon resonance sensing are described and documented on a number of examples. Localized plasmon sensing and surface-enhanced Raman spectroscopy are subjected to special interest since those techniques are inherently associated with the direct application of plasmonic structures. The possibility of tailoring the optical properties of ultra-thin metal layers via controlling their shape and morphology by postdeposition annealing is documented. Special attention is paid to the contribution of bimetallic particles and layers as well as metal structures encapsulated in semiconductors and dielectrics to the optical response. The opportunity to tune the properties of materials over a large scale of values opens up entirely new application possibilities of optical active structures. The nature of surface plasmons predetermines noble metal nanostructures to be promising great materials for development of modern label-free sensing methods based on plasmon resonance—SPR and LSPR sensing.

scholarly journals Recent Advances in the Fabrication and Functionalization of Flexible Optical Biosensors: Toward Smart Life-Sciences Applications

Biosensors ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 107
Author(s):  
Bruno Miranda ◽  
Ilaria Rea ◽  
Principia Dardano ◽  
Luca De Stefano ◽  
Carlo Forestiere
Keyword(s):  
Large Scale ◽  
High Specificity ◽  
Cost Effective ◽  
Surface Enhanced Raman Spectroscopy ◽  
Great Sensitivity ◽  
Noble Metal Nanoparticles ◽  
Localized Surface Plasmon ◽  
Optical Biosensors ◽  
Planar Surfaces

Over the last 30 years, optical biosensors based on nanostructured materials have obtained increasing interest since they allow the screening of a wide variety of biomolecules with high specificity, low limits of detection, and great sensitivity. Among them, flexible optical platforms have the advantage of adapting to non-planar surfaces, suitable for in vivo and real-time monitoring of diseases and assessment of food safety. In this review, we summarize the newest and most advanced platforms coupling optically active materials (noble metal nanoparticles) and flexible substrates giving rise to hybrid nanomaterials and/or nanocomposites, whose performances are comparable to the ones obtained with hard substrates (e.g., glass and semiconductors). We focus on localized surface plasmon resonance (LSPR)-based and surface-enhanced Raman spectroscopy (SERS)-based biosensors. We show that large-scale, cost-effective plasmonic platforms can be realized with the currently available techniques and we emphasize the open issues associated with this topic.

scholarly journals Light-Scattering Simulations from Spherical Bimetallic Core–Shell Nanoparticles

Micromachines ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 359
Author(s):  
Francesco Ruffino
Keyword(s):  
Optical Properties ◽  
Light Scattering ◽  
Bimetallic Nanoparticles ◽  
Dominant Role ◽  
Scattered Light ◽  
Specific Interaction ◽  
Surface Enhanced Raman Spectroscopy ◽  
Localized Surface Plasmon ◽  
Core Shell ◽  
The Core

Bimetallic nanoparticles show novel electronic, optical, catalytic or photocatalytic properties different from those of monometallic nanoparticles and arising from the combination of the properties related to the presence of two individual metals but also from the synergy between the two metals. In this regard, bimetallic nanoparticles find applications in several technological areas ranging from energy production and storage to sensing. Often, these applications are based on optical properties of the bimetallic nanoparticles, for example, in plasmonic solar cells or in surface-enhanced Raman spectroscopy-based sensors. Hence, in these applications, the specific interaction between the bimetallic nanoparticles and the electromagnetic radiation plays the dominant role: properties as localized surface plasmon resonances and light-scattering efficiency are determined by the structure and shape of the bimetallic nanoparticles. In particular, for example, concerning core-shell bimetallic nanoparticles, the optical properties are strongly affected by the core/shell sizes ratio. On the basis of these considerations, in the present work, the Mie theory is used to analyze the light-scattering properties of bimetallic core–shell spherical nanoparticles (Au/Ag, AuPd, AuPt, CuAg, PdPt). By changing the core and shell sizes, calculations of the intensity of scattered light from these nanoparticles are reported in polar diagrams, and a comparison between the resulting scattering efficiencies is carried out so as to set a general framework useful to design light-scattering-based devices for desired applications.

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