scholarly journals An Exploration into the Detection of COVID-19 from Chest X-ray Scans Using the xRGM-NET Convolutional Neural Network

Technologies ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 98
Author(s):  
Gabriel Ackall ◽  
Mohammed Elmzoudi ◽  
Richard Yuan ◽  
Cuixian Chen

COVID-19 has spread rapidly across the world since late 2019. As of December, 2021, there are over 250 million documented COVID-19 cases and over 5 million deaths worldwide, which have caused businesses, schools, and government operations to shut down. The most common method of detecting COVID-19 is the RT-PCR swab test, which suffers from a high false-negative rate and a very slow turnaround for results, often up to two weeks. Because of this, specialists often manually review X-ray images of the lungs to detect the presence of COVID-19 with up to 97% accuracy. Neural network algorithms greatly accelerate this review process, analyzing hundreds of X-rays in seconds. Using the Cohen COVID-19 X-ray Database and the NIH ChestX-ray8 Database, we trained and constructed the xRGM-NET convolutional neural network (CNN) to detect COVID-19 in X-ray scans of the lungs. To further aid medical professionals in the manual review of X-rays, we implemented the CNN activation mapping technique Score-CAM, which generates a heat map over an X-ray to illustrate which areas in the scan are most influential over the ultimate diagnosis. xRGM-NET achieved an overall classification accuracy of 97% with a sensitivity of 94% and specificity of 97%. Lightweight models like xRGM-NET can serve to improve the efficiency and accuracy of COVID-19 detection in developing countries or rural areas. In this paper, we report on our model and methods that were developed as part of a STEM enrichment summer program for high school students. We hope that our model and methods will allow other researchers to create lightweight and accurate models as more COVID-19 X-ray scans become available.

2021 ◽  
Vol 2071 (1) ◽  
pp. 012001
Author(s):  
J Ureta ◽  
A Shrestha

Abstract Tuberculosis(TB) is one of the top 10 causes of death worldwide, and drug-resistant TB is a major public health concern especially in resource-constrained countries. In such countries, molecular diagnosis of drug-resistant TB remains a challenge; and imaging tools such as X-rays, which are cheaply and widely available, can be a valuable supplemental resource for early detection and screening. This study uses a specialized convolutional neural network to perform binary classification of chest X-ray images to classify drug-resistant and drug-sensitive TB. The models were trained and validated using the TBPortals dataset which contains 2,973 labeled X-ray images from TB patients. The classifiers were able to identify the presence or absence of drug-resistant Tuberculosis with an AUROC between 0.66–0.67, which is an improvement over previous attempts using deep learning networks.


2021 ◽  
Vol 11 (21) ◽  
pp. 10301
Author(s):  
Muhammad Shoaib Farooq ◽  
Attique Ur Rehman ◽  
Muhammad Idrees ◽  
Muhammad Ahsan Raza ◽  
Jehad Ali ◽  
...  

COVID-19 has been difficult to diagnose and treat at an early stage all over the world. The numbers of patients showing symptoms for COVID-19 have caused medical facilities at hospitals to become unavailable or overcrowded, which is a major challenge. Studies have recently allowed us to determine that COVID-19 can be diagnosed with the aid of chest X-ray images. To combat the COVID-19 outbreak, developing a deep learning (DL) based model for automated COVID-19 diagnosis on chest X-ray is beneficial. In this research, we have proposed a customized convolutional neural network (CNN) model to detect COVID-19 from chest X-ray images. The model is based on nine layers which uses a binary classification method to differentiate between COVID-19 and normal chest X-rays. It provides COVID-19 detection early so the patients can be admitted in a timely fashion. The proposed model was trained and tested on two publicly available datasets. Cross-dataset studies are used to assess the robustness in a real-world context. Six hundred X-ray images were used for training and two hundred X-rays were used for validation of the model. The X-ray images of the dataset were preprocessed to improve the results and visualized for better analysis. The developed algorithm reached 98% precision, recall and f1-score. The cross-dataset studies also demonstrate the resilience of deep learning algorithms in a real-world context with 98.5 percent accuracy. Furthermore, a comparison table was created which shows that our proposed model outperforms other relative models in terms of accuracy. The quick and high-performance of our proposed DL-based customized model identifies COVID-19 patients quickly, which is helpful in controlling the COVID-19 outbreak.


2020 ◽  
Author(s):  
Amit Kumar Jaiswal ◽  
Prayag Tiwari ◽  
Vipin Kumar Rathi ◽  
Jia Qian ◽  
Hari Mohan Pandey ◽  
...  

The trending global pandemic of COVID-19 is the fastest ever impact which caused people worldwide by severe acute respiratory syndrome~(SARS)-driven coronavirus. However, several countries suffer from the shortage of test kits and high false negative rate in PCR test. Enhancing the chest X-ray or CT detection rate becomes critical. The patient triage is of utmost importance and the use of machine learning can drive the diagnosis of chest X-ray or CT image by identifying COVID-19 cases. To tackle this problem, we propose~COVIDPEN~-~a transfer learning approach on Pruned EfficientNet-based model for the detection of COVID-19 cases. The proposed model is further interpolated by post-hoc analysis for the explainability of the predictions. The effectiveness of our proposed model is demonstrated on two systematic datasets of chest radiographs and computed tomography scans. Experimental results with several baseline comparisons show that our method is on par and confers clinically explicable instances, which are meant for healthcare providers.


2021 ◽  
Vol 8 (3) ◽  
pp. 533
Author(s):  
Budi Nugroho ◽  
Eva Yulia Puspaningrum

<p class="Abstrak">Saat ini banyak dikembangkan proses pendeteksian pneumonia berdasarkan citra paru-paru dari hasil foto rontgen (x-ray), sebagaimana juga dilakukan pada penelitian ini. Metode yang digunakan adalah <em>Convolutional Neural Network</em> (CNN) dengan arsitektur yang berbeda dengan sejumlah penelitian sebelumnya. Selain itu, penelitian ini juga memodifikasi model CNN dimana metode <em>Extreme Learning Machine</em> (ELM) digunakan pada bagian klasifikasi, yang kemudian disebut CNN-ELM. Dataset untuk uji coba menggunakan kumpulan citra paru-paru hasil foto rontgen pada Kaggle yang terdiri atas 1.583 citra normal dan 4.237 citra pneumonia. Citra asal pada dataset kaggle ini bervariasi, tetapi hampir semua diatas ukuran 1000x1000 piksel. Ukuran citra yang besar ini dapat membuat pemrosesan klasifikasi kurang efektif, sehingga mesin CNN biasanya memodifikasi ukuran citra menjadi lebih kecil. Pada penelitian ini, pengujian dilakukan dengan variasi ukuran citra input, untuk mengetahui pengaruhnya terhadap kinerja mesin pengklasifikasi. Hasil uji coba menunjukkan bahwa ukuran citra input berpengaruh besar terhadap kinerja klasifikasi pneumonia, baik klasifikasi yang menggunakan metode CNN maupun CNN-ELM. Pada ukuran citra input 200x200, metode CNN dan CNN-ELM menunjukkan kinerja paling tinggi. Jika kinerja kedua metode itu dibandingkan, maka Metode CNN-ELM menunjukkan kinerja yang lebih baik daripada CNN pada semua skenario uji coba. Pada kondisi kinerja paling tinggi, selisih akurasi antara metode CNN-ELM dan CNN mencapai 8,81% dan selisih F1 Score mencapai 0,0729. Hasil penelitian ini memberikan informasi penting bahwa ukuran citra input memiliki pengaruh besar terhadap kinerja klasifikasi pneumonia, baik klasifikasi menggunakan metode CNN maupun CNN-ELM. Selain itu, pada semua ukuran citra input yang digunakan untuk proses klasifikasi, metode CNN-ELM menunjukkan kinerja yang lebih baik daripada metode CNN.</p><p class="Abstrak"> </p><p class="Abstrak"><em><strong>Abstract</strong></em></p><p class="Abstract"><em>This research developed a pneumonia detection machine based on the lungs' images from X-rays (x-rays). The method used is the Convolutional Neural Network (CNN) with a different architecture from some previous research. Also, the CNN model is modified, where the classification process uses the Extreme Learning Machine (ELM), which is then called the CNN-ELM method. The empirical experiments dataset used a collection of lung x-ray images on Kaggle consisting of 1,583 normal images and 4,237 pneumonia images. The original image's size on the Kaggle dataset varies, but almost all of the images are more than 1000x1000 pixels. For classification processing to be more effective, CNN machines usually use reduced-size images. In this research, experiments were carried out with various input image sizes to determine the effect on the classifier's performance. The experimental results show that the input images' size has a significant effect on the classification performance of pneumonia, both the CNN and CNN-ELM classification methods. At the 200x200 input image size, the CNN and CNN-ELM methods showed the highest performance. If the two methods' performance is compared, then the CNN-ELM Method shows better performance than CNN in all test scenarios. The difference in accuracy between the CNN-ELM and CNN methods reaches 8.81% at the highest performance conditions, and the difference in F1-Score reaches 0.0729. This research provides important information that the size of the input image has a major influence on the classification performance of pneumonia, both classification using the CNN and CNN-ELM methods. Also, on all input image sizes used for the classification process, the CNN-ELM method shows better performance than the CNN method.</em></p>


Author(s):  
Omeshwar Singh ◽  
Anuradha Sen ◽  
Sumeet Singh Charak ◽  
Shakeel Ahmad

Background: Wrists injuries are one of the common presentations to emergency departments and orthopaedic clinics. The scaphoid bone is the most commonly injured of the carpal bones accounting for 50-80% of carpal injuries and predominantly occurs in young healthy individuals. Scaphoid fractures are the most problematic to diagnose in a clinical setting because it can take up to 6 weeks for scaphoid fractures to become conclusive on plain X-ray films. Aim of the study was to retrospective study was carried out to study the role of early CT scan in diagnosis of occult scaphoid fractures.Methods: A total of 123 patients presented with an acute wrist injury with subsequent signs of scaphoid injury in the absence of a diagnostic fracture on plain X-ray within the time period from June 2014 to May 2016 in a tertiary care centre.Results: This study shows that 31% of normal X-rays were pathological on CT scan and out of these; scaphoid fractures (74% of pathologies) represent a large number of patients with fractures that were missed by initial plain films.Conclusions: This study shows an extremely high false-negative rate for plain X-rays and advocate CT at the first attendance to fracture clinic if there is suspicion of scaphoid injury. An earlier diagnosis leads to appropriate management and reduces restrictions to the patient in terms of prolonged immobilization and repeated clinical reviews.


Author(s):  
Lawrence Hall ◽  
Dmitry Goldgof ◽  
Rahul Paul ◽  
Gregory M. Goldgof

<p>Testing for COVID-19 has been unable to keep up with the demand. Further, the false negative rate is projected to be as high as 30% and test results can take some time to obtain. X-ray machines are widely available and provide images for diagnosis quickly. This paper explores how useful chest X-ray images can be in diagnosing COVID-19 disease. We have obtained 122 chest X-rays of COVID-19 and over 4,000 chest X-rays of viral and bacterial pneumonia. Unfortunately, we missed the fact that the chest X-rays of viral and bacterial pneumonia came from children under 5 years old. So, this work shows that you can tell kids with pneumonia from COVID-19 adult cases which is not anyone's goal. However, data from adult chest X-rays of other causes of lung disease is needed to see if you can tell adult diseases apart.<br></p>


2020 ◽  
Vol 10 (9) ◽  
pp. 3233 ◽  
Author(s):  
Tawsifur Rahman ◽  
Muhammad E. H. Chowdhury ◽  
Amith Khandakar ◽  
Khandaker R. Islam ◽  
Khandaker F. Islam ◽  
...  

Pneumonia is a life-threatening disease, which occurs in the lungs caused by either bacterial or viral infection. It can be life-endangering if not acted upon at the right time and thus the early diagnosis of pneumonia is vital. The paper aims to automatically detect bacterial and viral pneumonia using digital x-ray images. It provides a detailed report on advances in accurate detection of pneumonia and then presents the methodology adopted by the authors. Four different pre-trained deep Convolutional Neural Network (CNN): AlexNet, ResNet18, DenseNet201, and SqueezeNet were used for transfer learning. A total of 5247 chest X-ray images consisting of bacterial, viral, and normal chest x-rays images were preprocessed and trained for the transfer learning-based classification task. In this study, the authors have reported three schemes of classifications: normal vs. pneumonia, bacterial vs. viral pneumonia, and normal, bacterial, and viral pneumonia. The classification accuracy of normal and pneumonia images, bacterial and viral pneumonia images, and normal, bacterial, and viral pneumonia were 98%, 95%, and 93.3%, respectively. This is the highest accuracy, in any scheme, of the accuracies reported in the literature. Therefore, the proposed study can be useful in more quickly diagnosing pneumonia by the radiologist and can help in the fast airport screening of pneumonia patients.


Diagnostics ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 209 ◽  
Author(s):  
Vo Truong Nhu Ngoc ◽  
Agwu Chinedu Agwu ◽  
Le Hoang Son ◽  
Tran Manh Tuan ◽  
Cu Nguyen Giap ◽  
...  

In dental diagnosis, recognizing tooth complications quickly from radiology (e.g., X-rays) takes highly experienced medical professionals. By using object detection models and algorithms, this work is much easier and needs less experienced medical practitioners to clear their doubts while diagnosing a medical case. In this paper, we propose a dental defect recognition model by the integration of Adaptive Convolution Neural Network and Bag of Visual Word (BoVW). In this model, BoVW is used to save the features extracted from images. After that, a designed Convolutional Neural Network (CNN) model is used to make quality prediction. To evaluate the proposed model, we collected a dataset of radiography images of 447 patients in Hanoi Medical Hospital, Vietnam, with third molar complications. The results of the model suggest accuracy of 84% ± 4%. This accuracy is comparable to that of experienced dentists and radiologists.


2020 ◽  
Vol 14 (suppl 1) ◽  
pp. 869-878
Author(s):  
Peeyush Kumar ◽  
Ayushe Gangal ◽  
Sunita Kumari

Coronavirus is a large virus family consisting of diverse viruses, some of which disseminate among mammals and others cause sickness among humans. COVID-19 is highly contagious and is rapidly spreading, rendering its early diagnosis of preeminent status. Researchers, medical specialists and organizations all over the globe have been working tirelessly to combat this virus and help in its containment. In this paper, a novel neural network called WisdomNet has been proposed, for the diagnosis of COVID-19 using chest X-rays. The WisdomNet uses the concept of ‘Wisdom of Crowds’ as its founding idea. It is a two-layered convolutional Neural Network (CNN), which takes chest x-ray images as input. Both layers of the proposed neural network consist of a number of neural networks each. The dataset used for this study consists of chest x-ray images of COVID-19 positive patients, compiled and shared by Dr. Cohen on GitHub, and the chest x-ray images of healthy lungs and lungs affected by viral and bacterial pneumonia were obtained from Kaggle. The network not only pinpoints the presence of COVID-19, but also gives the probability of the disease maturing into Acute Respiratory Distress Syndrome (ARDS). Thus, predicting the progression of the disease in the COVID-19 positive patients. The network also slender the occurrences of false negative cases by employing a high threshold value, thus aids in curbing the spread of the disease and gives an accuracy of 100% for successfully predicting COVID-19 among the chest x-rays of patients affected with COVID-19, bacterial and viral pneumonia.


Author(s):  
Lawrence Hall ◽  
Dmitry Goldgof ◽  
Rahul Paul ◽  
Gregory M. Goldgof

<p>Testing for COVID-19 has been unable to keep up with the demand. Further, the false negative rate is projected to be as high as 30% and test results can take some time to obtain. X-ray machines are widely available and provide images for diagnosis quickly. This paper explores how useful chest X-ray images can be in diagnosing COVID-19 disease. We have obtained 122 chest X-rays of COVID-19 and over 4,000 chest X-rays of viral and bacterial pneumonia. A pre-trained deep convolutional neural network has been tuned on 102 COVID-19 cases and 102 other pneumonia cases in a 10-fold cross validation. The results were all 102 COVID-19 cases were correctly classified and there were 8 false positives resulting in an AUC of 0.997. On a test set of 20 unseen COVID-19 cases all were correctly classified and more than 95% of 4,171 other pneumonia examples were correctly classified. This study has flaws, most critically a lack of information about where in the disease process the COVID-19 cases were and the small data set size. More COVID-19 case images will enable a better answer to the question of how useful chest X-rays can be for diagnosing COVID-19 (so please send them). </p>


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