scholarly journals Whole Genome Analysis Revealed the Genes Responsible for Citreoviridin Biosynthesis in Penicillium citreonigrum

Toxins ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 125
Author(s):  
Takumi Okano ◽  
Naoki Kobayashi ◽  
Kazuki Izawa ◽  
Tomoya Yoshinari ◽  
Yoshiko Sugita-Konishi
Keyword(s):  
Gene Cluster ◽  
Biosynthetic Pathway ◽  
Aspergillus Terreus ◽  
Draft Genome ◽  
Agricultural Products ◽  
Whole Genome Analysis ◽  
Homologous Genes ◽  
Wide Range ◽  
The World ◽  
Highly Correlated

Citreoviridin (CTV) is a mycotoxin that is produced by Aspergillus terreus, Eupenicillium ochrosalmoneum and Penicillium citreonigrum, and CTV has been detected in a wide range of cereal grains throughout the world. Furthermore, it is especially a serious problem in regions where rice is consumed as a staple food. Moreover, CTV is a well-known yellow rice toxin, and outbreaks of beriberi have occurred due to consumption of rice that is contaminated by CTV even in the recent years. Although CTV biosynthetic genes of A. terreus have been described, those of P. citreonigrum remain unclear, which is concerning since P. citreonigrum is the main cause of CTV contamination in rice. In the present study, we determined the draft genome of the P. citreonigrum strain IMI92228 and revealed the presence of all four genes that form a gene cluster and that are homologous to the CTV biosynthesis genes of A. terreus. The expression of these four homologous genes were highly correlated with CTV production, suggesting that they may play an important role in CTV biosynthesis in P. citreonigrum. We concluded that the gene cluster is a CTV biosynthesis cluster of P. citreonigrum. The findings will contribute to the understanding of the biosynthetic pathway of CTV and will ultimately lead to improvements in the CTV management of agricultural products.

scholarly journals Piggyback as an element of the agricultural products supply to the world market

2019 ◽  
pp. 74-79
Author(s):  
T. Larina ◽  
A. Litvinov ◽  
O. Potyshnyak
Keyword(s):  
Supply Chains ◽  
Value Added ◽  
World Market ◽  
Economic Feasibility ◽  
Agricultural Products ◽  
Raw Material ◽  
Added Value ◽  
Wide Range ◽  
The World ◽  
Agricultural Supply

The purpose of the presented research is to analyze the prospects of piggyback in improving the efficiency of or-ganization of agricultural supply chains to the world market. Ukraine is characterized by a high level of logistical com-ponent in transportation of agricultural products, which actualizes the issue of managed transformations in this field. The arguments and counterarguments on the viability of the strategy of using piggyback in the practice of build-ing a supply chain in the context of the agrarian market are analyzed. The basis of the formation of the author's vision is based on the criterion of economic feasibility. Attention was paid to the potential of piggyback in mitigating the situa-tion in the organization of agricultural supply chains by reducing: the need for storage capacities, expanding the range of exporting entities, smoothing the situation of shortages of hopper wagons. At the same time, the actual updating of the piggyback mechanism is connected with the change of the structure of Ukrainian agro-export, in the transition from the practice of raw material appendage to the strategy of creation of production chains with high added value. It is noted that the key feature of agro-logistics is the objective need to form highly specialized segments within it. Each group of a wide range of agricultural products requires an individual, non-uniform approach in the logistics of intermodal trans-portation. Piggyback is recognized as a promising direction for the development of the logistics services market in Ukraine. However, their implementation in the practice of organizing agricultural supply chains has objective limita-tions. The segment agricultural group where piggyback is economically viable includes high-value elite agricultural products with a small average export batch, as well as high value-added agro-industrial products. Key words: world market, piggyback, supply chains, international logistics, agricultural products, exports.

scholarly journals INFRASTRUCTURE PROVISION OF THE AGRARIAN MARKET IN THE GLOBALIZED ENVIRONMENT

2020 ◽  
Vol 5 (5) ◽  
pp. 39 ◽  
Author(s):  
Olga Vyshnevska ◽  
Olena Kaliuzhna ◽  
Inna Irtyshcheva
Keyword(s):  
Food Security ◽  
Global Market ◽  
Agricultural Products ◽  
Advantages And Disadvantages ◽  
Infrastructure Provision ◽  
Wide Range ◽  
Hidden Hunger ◽  
The World ◽  
Marketing Activities ◽  
Banking Institutions

The main results of the research, which consist in determining the essence and features of the infrastructure provision of the agrarian market in the globalized environment, are formed. The priority of approaches in the development of logistics activities in the context of guaranteeing food security of regions and countries of the world is determined. The essence of the logistic process, strengthening the influence of the global market on the quality of agrarian products, is determined. The influence of the infrastructure provision of the agrarian market on the competitive positions of commodity producers is generalized, advantages and disadvantages in development are determined. The essence of informational logistics, its influence on the development of infrastructure provision of agricultural products market, satisfaction of consumers’ needs is investigated. The urgency of the introduction of e-commerce, which allows commodity producers to combine marketing activities with optimization of advertising costs, to ensure the efficiency and convenience of carrying out operations for the sale of agricultural products, its transportation, manage all logistics processes. It is proved that improvement of the infrastructure provision of the agrarian market of the world countries that adapts to the global market should be based on the dissemination of information opportunities, and the interaction of all participants in the process of selling agricultural products on an e-commerce basis, i.e. on cooperation of the network of producers, banking institutions, Internet providers, supermarket chains, processing enterprises, including export-oriented agricultural products, as well as regional representatives of state authorities. The combination of actions and systematical implementation of the logistical approach will reduce the level of information, production, business risks, as well as significantly increase the export opportunities of producers of agrarian products, especially in the context of the urgency of the issue of ensuring food security of the world, its regions and countries. It is stipulated that in the global market the solution of a problem should have a wide range of actions that should be directed at the ordering of economic, social and environmental interests of the world society. It is proved that improvement of the infrastructure provision of the agrarian market should be a matter of food safety and availability, considering the need to level out obvious and hidden hunger, and not only the spread of innovative technologies of production and the receipt of super-profits.

scholarly journals Inactivation of mrpigH Gene in Monascus ruber M7 Results in Increased Monascus Pigments and Decreased Citrinin with mrpyrG Selection Marker

2021 ◽  
Vol 7 (12) ◽  
pp. 1094
Author(s):  
Li Li ◽  
Na Xu ◽  
Fusheng Chen
Keyword(s):  
Gene Cluster ◽  
Biosynthetic Pathway ◽  
Selection Marker ◽  
Asian Countries ◽  
Gene Modification ◽  
Monascus Ruber ◽  
Modification System ◽  
Monascus Pigments ◽  
Efficient Gene ◽  
The World

Monascus pigments (MPs) have been used as food colorants for several centuries in Asian countries and are currently used around the world via Asian catering. The MPs biosynthetic pathway has been well-illustrated; however, the functions of a few genes including mrpigH in the MPs gene cluster of M. ruber M7 are still unclear. In the current study, mrpigH was disrupted in Δmrlig4ΔmrpyrG, a highly efficient gene modification system, using mrpyrG as a selection marker, and ΔmrpigHΔmrlig4ΔmrpyrG::mrpyrG and ΔmrpigHΔmrlig4ΔmrpyrG have been obtained. Subsequently, their morphologies, biomasses, MPs and citrinin (CIT) production were analyzed, respectively. These results have revealed that the deletion of mrpigH has significant effects on the morphology and growth of M. ruber M7. Moreover, compared with M. ruber M7, the yields of MPs and CIT were drastically increased and decreased in mrpigH mutants, respectively.

Creative Strategy Used in Electronic Advertising

GIS Business ◽  
2019 ◽  
Vol 14 (6) ◽  
pp. 597-606
Author(s):  
Dr. Maha Mustafa Omer Abdalaziz
Keyword(s):  
The Internet ◽  
Business Organizations ◽  
Creative Strategy ◽  
Electronic Environment ◽  
Wide Range ◽  
The World ◽  
Technological Developments ◽  
Electronic Advertising

The study aims at the technological developments that are taking place in the world and have impacted on all sectors and fields and imposed on the business organizations and commercial companies to carry out their marketing and promotional activities within the electronic environment. The most prominent of these developments is the emergence of the concept of electronic advertising which opened a wide range of companies and businessmen to advertise And to promote their products and their work easily through the Internet, which has become full of electronic advertising, and in light of that will discuss the creative strategy used in electronic advertising;

ARTISTIC ASSIMILATION OF THE WORLD IN THE ESSAY PROSE OF M. G. ATAMANOV (BASED ON THE BOOK “I AM UDMURT. WHY DOES IT HURT?”)

2020 ◽  
Vol 14 (3) ◽  
pp. 459-464
Author(s):  
Alevtina Vasilevna Kamitova ◽  
Tatyana Ivanovna Zaitseva
Keyword(s):  
Ethnic Identity ◽  
National Identity ◽  
National Culture ◽  
Native Language ◽  
Topographic Features ◽  
Wide Range ◽  
The World ◽  
The Subject ◽  
Individual Style

The paper reflects the specificity of the fundamental ideas of the artistic world of M. G. Atamanov, which includes a wide range of literary facts from the content level of the text of the works to their poetics. A particularly important role in the works of M. G. Atamanov is played by cross-cutting themes and images that reflect the author's individual style and his idea of national-ethnic identity. The subject of the research is the book of essays “Mon - Udmurt. Maly mynym vös’?” (“I am Udmurt. Why does it hurt?”), which most vividly reflected the main spiritual and artistic searches of M. G. Atamanov, associated with his ideas about the Udmurt people. The main motives and plots of the works included in the book under consideration are accumulated around the concept of “Udmurtness”. The comprehension of “Udmurtness” is modeled in his essays through specific leit themes: native language, Udmurt people, national culture, mentality, geographic and topographic features of the Udmurt people’ places of residence, the Orthodox idea. The “Udmurt theme” is recognized and comprehended by the writer through the prism of national identity.

Potential Triazole-based Molecules for the Treatment of Neglected Diseases

2019 ◽  
Vol 26 (23) ◽  
pp. 4403-4434 ◽  
Author(s):  
Susimaire Pedersoli Mantoani ◽  
Peterson de Andrade ◽  
Talita Perez Cantuaria Chierrito ◽  
Andreza Silva Figueredo ◽  
Ivone Carvalho
Keyword(s):  
Effective Treatment ◽  
Chagas Disease ◽  
Medicinal Chemistry ◽  
Biological Activities ◽  
Neglected Diseases ◽  
Triazole Derivatives ◽  
Wide Range ◽  
The World ◽  
Great Relevance ◽  
The Moment

Neglected Diseases (NDs) affect million of people, especially the poorest population around the world. Several efforts to an effective treatment have proved insufficient at the moment. In this context, triazole derivatives have shown great relevance in medicinal chemistry due to a wide range of biological activities. This review aims to describe some of the most relevant and recent research focused on 1,2,3- and 1,2,4-triazolebased molecules targeting four expressive NDs: Chagas disease, Malaria, Tuberculosis and Leishmaniasis.

Healthcare apps on smartphones available in Brazil: a preliminary classification (Preprint)

2020 ◽  
Author(s):  
André De Faria Pereira Neto ◽  
Leticia Barbosa ◽  
Rodolfo Paolucci
Keyword(s):  
Health Promotion ◽  
Disease Prevention ◽  
Digital Health ◽  
Disease Process ◽  
World Health ◽  
Computing Device ◽  
Care Treatment ◽  
Wide Range ◽  
The World ◽  
Health Applications

UNSTRUCTURED Billions of people in the world own a smartphone. It is a low-cost, portable computing device with countless features, among which applications stand out, which are programs or software developed to meet a specific goal. A wide range of applications available ranging from entertainment and personal organization to work and education is available currently. It is a vast and profitable market. Health applications have been a means of intervention for different areas, including chronic diseases, epidemics, and health emergencies. A recently published paper in the journal with the highest impact factor in Digital Health (“Journal of Medical Internet Research”) proposes a classification of health applications. This study performs a critical analysis of this organization and presents other sort criteria. This paper also presents and analyzes the “Meu Info Saúde” (“My Health Info”) app – a pioneering government initiative focused on primary care launched by the Oswaldo Cruz Foundation. The application classification proposal that will be presented builds on the intervention strategies in the health-disease process, namely: “Health Promotion”, “Disease Prevention” and “Care, Treatment and Rehabilitation”, as defined by official documents such as the World Health Organization and the Centers for Disease Control and Prevention. Most applications present in the sample are of private and foreign origin, free to download, but with a display of ads or the sale of products and services. The sampled applications were classified as “Health Promotion”, and some applications have also been categorized as “Disease Prevention” or “Care, Treatment or Rehabilitation” because they have multiple functionalities. The applications identified as “Health Promotion” focused only on individuals’ lifestyle and their increased autonomy and self-care management capacity. From this perspective, the apps analyzed in this paper differ from the “Meu Info-Saúde” application developed at Fiocruz.

Introduction

2018 ◽  
Author(s):  
Michael C. Legaspi
Keyword(s):  
Western Culture ◽  
Profound Influence ◽  
Wide Range ◽  
The World ◽  
Way Of Thinking

This is a book about wisdom. It is an inquiry into the beginnings of a particular way of thinking about life in the world. Seen in terms of wisdom, the world is not a meaningless array of disconnected things but something that is experienced as an ordered reality. This holistic way of understanding life in the world characterized pursuits of wisdom in a two-sided classical and biblical tradition that exercised a profound influence on Western culture. This book examines the development of that tradition in a wide range of texts from Homer to Plato and in the writings of early Jewish and Christian authors.

Introduction

2018 ◽  
Author(s):  
Anna-Maria Hartmann
Keyword(s):  
Sixteenth Century ◽  
Early Modern ◽  
Literary History ◽  
First Generation ◽  
Early Modern England ◽  
Related Material ◽  
Wide Range ◽  
The World ◽  
Early English

Mythographies were books that collected, explained, and interpreted myth-related material. Extremely popular during the Renaissance, these works appealed to a wide range of readers. While the European mythographies of the sixteenth century have been utilized by scholars, the short, early English mythographies, written from 1577 to 1647, have puzzled critics. The first generation of English mythographers did not, as has been suggested, try to compete with their Italian predecessors. Instead, they made mythographies into rhetorical instruments designed to intervene in topical debates outside the world of classical learning. Because English mythographers brought mythology to bear on a variety of contemporary issues, they unfold a lively and historically well-defined picture of the roles myth was made to play in early modern England. Exploring these mythographies can contribute to previous insights into myth in the Renaissance offered by studies of iconography, literary history, allegory, and myth theory.

Competitiveness of dried sector: A case study of world and Turkey

2020 ◽  
Vol 66 (No. 8) ◽  
pp. 365-372
Author(s):  
Tunahan Erdem
Keyword(s):  
Agricultural Products ◽  
The Other ◽  
Local Currency ◽  
Political Crises ◽  
The World ◽  
World Economic ◽  
World Economic Crisis ◽  
Specific Country ◽  
Economic Outlook

The study aimed to reveal the competitiveness of the world dried sector for some selected products such as dried apples, prunes, apricots, figs, and grapes. In the study, the data was subjected to the Revealed Comparative Advantage (RCA), Relative Export Advantage (RXA), Relative Import Advantage (RMA), Relative Trade Advantage (RTA) and Relative Competitiveness (RC) indices. RCA is an index developed by Balassa to determine the competitiveness of a specific country for selected products or goods. To demonstrate the economic outlook for the world dried sector, the 2007 to 2017 data of China, USA, Chile, Germany, Iran, the Netherlands, South Africa, France, Uzbekistan, Argentina, Spain, Turkey, and India were compared, these countries dominating the sector of selected dried agricultural products. The results demonstrated that the world dried sector is very responsive to economic crises and to local currency rate. The RCA index was found to be 4.66 in 2007 for Turkey and it decreased to 4.45 by 2009 during the world economic crisis. The other breaking point was 2013 when Turkey experienced both economic and political crises.

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