scholarly journals Cancer Vaccines and Immunotherapy for Tumor Prevention and Treatment

Vaccines ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1298
Author(s):  
Jagmohan Singh ◽  
Wilbur B. Bowne ◽  
Adam E. Snook
Keyword(s):  
Immune Responses ◽  
Cancer Vaccines ◽  
New Technologies ◽  
Special Issue ◽  
Future Directions ◽  
Prevention And Treatment ◽  
Recent Developments ◽  
Tumor Prevention ◽  
Therapeutic Cancer Vaccines ◽  
Made In

In this editorial, we highlight articles published in this Special Issue of Vaccines on “Cancer Vaccines and Immunotherapy for Tumor Prevention and Treatment”, recent developments in the field of cancer vaccines, and the potential for immunotherapeutic combinations in cancer care. This issue covers important developments and progress being made in the cancer vaccine field and possible future directions for exploring new technologies to produce optimal immune responses against cancer and expand the arena of prophylactic and therapeutic cancer vaccines for the treatment of this deadly disease.

Protein transport in the plant secretory pathwayThis review is one of a selection of papers published in the Special Issue on Plant Cell Biology.

2006 ◽  
Vol 84 (4) ◽  
pp. 523-530 ◽  
Author(s):  
Sally L. Hanton ◽  
Federica Brandizzi
Keyword(s):  
Plant Cell ◽  
Cell Biology ◽  
Secretory Pathway ◽  
Protein Transport ◽  
New Technologies ◽  
Special Issue ◽  
Recent Developments ◽  
Selection Of ◽  
Made In

The study of the plant secretory pathway is a relatively new field, developing rapidly over the last 30 years. Many exciting discoveries have already been made in this area, but as old questions are answered new ones become apparent. Our understanding of the functions and mechanisms of the plant secretory pathway is constantly expanding, in part because of the development of new technologies, mainly in bioimaging. The increasing accessibility of these new tools in combination with more established methods provides an ideal way to increase knowledge of the secretory pathway in plants. In this review we discuss recent developments in understanding protein transport between organelles in the plant secretory pathway.

scholarly journals Virus-Based Nanomaterials and Nanostructures

Nanomaterials ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 567
Author(s):  
Jin-Woo Oh ◽  
Dong-Wook Han
Keyword(s):  
Energy Harvesting ◽  
Tissue Regeneration ◽  
Biomedical Applications ◽  
Special Issue ◽  
Future Directions ◽  
Biomimetic Materials ◽  
Recent Developments ◽  
Energy Harvesting Devices

This Special Issue highlights the recent developments and future directions of virus-based nanomaterials and nanostructures in energy and biomedical applications. The virus-based biomimetic materials formulated using innovative ideas presented herein are characterized for the applications of biosensors and nanocarriers. The research contributions and trends based on virus-based materials, covering energy-harvesting devices to tissue regeneration over the last two decades, are described and discussed.

scholarly journals Cancer Vaccines: Research and Applications

Cancers ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1041 ◽  
Author(s):  
Vasso Apostolopoulos
Keyword(s):  
Cancer Research ◽  
Immune Responses ◽  
Cancer Vaccines ◽  
Special Issue ◽  
Major Focus ◽  
Delivery Methods ◽  
Tumor Associated Antigens ◽  
Tumor Microenvironments ◽  
Immune Therapies

Designing cancer vaccines has been at the forefront of cancer research for over two-and-a-half decades. In particular, delivery methods used to stimulate effective and long-lasting immune responses have been the major focus. This special issue presents new tumor associated antigens, delivery methods, combination immune therapies, methods of measuring immunity induced following cancer vaccinations, and mechanisms in understanding tumor microenvironments and immunosuppression—all beneficial for the design of improved cancer vaccines.

scholarly journals Current immunotherapeutic strategies in hepatocellular carcinoma: recent advances and future directions

2017 ◽  
Vol 10 (10) ◽  
pp. 805-814 ◽  
Author(s):  
Hwi Young Kim ◽  
Joong-Won Park
Keyword(s):  
Hepatocellular Carcinoma ◽  
Immune Responses ◽  
Cancer Vaccines ◽  
Immune Checkpoint Blockade ◽  
Recurrence Rates ◽  
Future Directions ◽  
Optimal Outcomes ◽  
Recent Advances ◽  
Promising Target ◽  
Tumor Stages

Hepatocellular carcinoma (HCC) is a common and serious health problem with high mortality. Treatment for HCC remains largely unsatisfactory owing to its high recurrence rates and frequent accompanying cirrhosis. In addition, the unique immune environment of the liver promotes tolerance, which, in conjunction with immune evasion by the disease, makes HCC a less promising target for conventional immunotherapy. However, recent advances in the immunotherapy have led to novel approaches to overcome these obstacles by manipulating and enhancing tumor-specific immune responses against HCC by using various modalities, such as cancer vaccines and immune checkpoint blockade. These treatments have shown both safety and promising outcomes in patients with HCC of various etiologies and tumor stages. Furthermore, combined strategies have been assessed to achieve optimal outcomes, by using immunotherapies with or without conventional treatments. This review briefly covers the background, recent advances, current issues, and future perspectives on immunotherapy in the field of HCC treatment.

Recent developments in therapeutic cancer vaccines

2005 ◽  
Vol 2 (2) ◽  
pp. 108-113 ◽  
Author(s):  
Michael A Morse ◽  
Stephen Chui ◽  
Amy Hobeika ◽  
H Kim Lyerly ◽  
Timothy Clay
Keyword(s):  
Cancer Vaccines ◽  
Recent Developments ◽  
Therapeutic Cancer Vaccines

scholarly journals Recovery in occupational health psychology and human resource management research: An Interview with Prof. Sabine Sonnentag and Prof. Ute Stephan

2021 ◽  
pp. 239700222110045
Author(s):  
Sabine Sonnentag ◽  
Ute Stephan ◽  
Johannes Wendsche ◽  
Jessica de Bloom ◽  
Christine Syrek ◽  
...  
Keyword(s):  
Health Psychology ◽  
Occupational Health ◽  
Academic Research ◽  
Management Research ◽  
Special Issue ◽  
Future Directions ◽  
Occupational Health Psychology ◽  
Current State ◽  
Recent Developments ◽  
Recovery Management

While academic research on recovery was rather segregated between occupational health psychology and management research at the beginning of the 20s century and streams of research developed independently, recent developments hint at a closing divide and better integration of recovery research across disciplines. This for example becomes evident in publications of researchers across the traditional outlets within both fields, as well as increasing close collaborations of researchers firmly rooted in one of the fields. In preparation of this special issue, the editors were interested in whether this development represents a convergence or even a true merging of research in these different disciplines. We therefore interviewed Prof. Sabine Sonnentag as expert from occupational health psychology research and Prof. Ute Stephan with expertise in management research. Both are excellent and world-famous researchers in their disciplines. We discussed the current state, the advances during the last years, and the future directions of recovery research in their respective fields. We also talked about their perspectives on integrative topics and about specific issues in both domains that might stimulate a new recovery management research agenda.

Developmental considerations in the investigation of conduct disorder

1993 ◽  
Vol 5 (1-2) ◽  
pp. 331-344 ◽  
Author(s):  
Dante Cicchetti ◽  
John E. Richters
Keyword(s):  
Conduct Disorder ◽  
Social Cognitive ◽  
Complex Form ◽  
Theoretical Framework ◽  
Special Issue ◽  
Cognitive Capacities ◽  
Developmental Levels ◽  
Conceptual Clarity ◽  
Prevention And Treatment ◽  
Made In

The papers in this special issue attest to the theoretical and empirical advances that have been made in understanding the epidemiology, subtypes, etiology, neuropsychology, psychobiology, course, consequences, prevention, and treatment of conduct disorder (CD) (see also Kazdin, 1987; Loeber, 1990; Loeber & Stouthamer-Loeber, 1986; Moffitt, 1990; Patterson, 1982; Robins, 1991; White, Moffitt, Earls, Robins, & Silva, 1990). A number of theoretical conceptualizations have been forwarded in an attempt to comprehend this complex form of disorder in children. Such divergence in thinking indicates that the topic of CD has evolved into an active and significant domain of inquiry. To date, however, there has been no unifying theoretical framework for bringing conceptual clarity to the diverse perspectives represented in the study of conduct disorder. Although existing work within particular disciplines and subdisciplines has provided substantial contributions to our understanding of CD, these accounts typically have not considered the broader matrix of complex and evolving biological, cognitive, socioemotional, representational, and social-cognitive capacities of the developing child. As a consequence, disparate theoretical formulations are often too narrow in focus to address the range of processes and mechanisms that will be necessary to explain adequately how and why manifestations of CD emerge, change overtime and are influenced by children's developmental levels.

scholarly journals Recent advances in biologic therapy of asthma and the role in therapy of chronic rhinosinusitis

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 412 ◽  
Author(s):  
Rohit Divekar ◽  
Devyani Lal
Keyword(s):  
Immune Responses ◽  
Chronic Rhinosinusitis ◽  
Biologic Therapy ◽  
Innate Immune ◽  
Cytokine Receptors ◽  
Nasal Airway ◽  
Recent Developments ◽  
Immune Pathways ◽  
End Stage ◽  
Made In

Great strides have been made in the last five years in understanding the pathology of chronic rhinosinusitis (CRS). CRS is now accepted to be the end-stage manifestation of inflammation resultant from various pathogenetic mechanisms. This has resulted in increasing recognition of distinct CRS endotypes. Such endotypes encompass a cluster of patients with similar pathogenic mechanisms that may have common therapeutic targets and responsiveness to interventions. The elucidation of mechanisms leading to the development of chronic upper (sino-nasal) airway inflammation has to some extent paralleled investigations of aberrant pathways operant in asthma. In this review, we focus on recent developments in understanding the innate immune pathways as well as adaptive (late) immune responses in CRS and asthma and their implication as potentially modifiable targets in CRS. Specific biologic therapy (that is, monoclonal antibodies targeting cytokines, cytokine receptors, or specific key molecules targeting inflammation) is an exciting proposition for the future of medical management of CRS. As of the writing of this article, the agents described are not approved for use in CRS; many have partial approval for use in asthma or are considered experimental.

scholarly journals Big Data Research for Social Science and Social Impact

2019 ◽  
Vol 12 (1) ◽  
pp. 180 ◽  
Author(s):  
Miltiadis D. Lytras ◽  
Anna Visvizi
Keyword(s):  
Social Sciences ◽  
Big Data ◽  
Social Science ◽  
Social Impact ◽  
Science Research ◽  
Special Issue ◽  
Future Directions ◽  
Policy Makers ◽  
Computer Science Research ◽  
Recent Developments

This Special Issue of Sustainability devoted to the topic of “Big Data Research for Social Sciences and Social Impact” attracted significant attention of scholars, practitioners, and policy-makers from all over the world. Locating themselves at the cross-section of advanced information systems and computer science research and insights from social science and engineering, all papers included in this Special Issue contribute to the debate on the use of big data in social sciences and big data social impact. By promoting a debate on the multifaceted challenges that our societies are exposed to today, this Special Issue offers an in-depth, integrative, well-organized, comparative study into the most recent developments shaping the future directions of interdisciplinary research and policymaking.

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