State of neuromuscular transmission in vibration disease, according to electroneuromyographic test

2020 ◽  
pp. 55-68
Author(s):  
Sergey Babanov
Keyword(s):  
Neuromuscular Transmission ◽  
System Development ◽  
Disease Type ◽  
Functional Mobility ◽  
Sensorimotor System ◽  
Muscular System ◽  
Vibration Disease ◽  
Regional Center ◽  
Occupational Disorders ◽  
Sensory Polyneuropathy

The article covers the particular features of the neuro-muscular system in vibration disease of various types and severity by electroneuromyographical tests at the Department of Occupational Disorders, Regional Center for Occupational Disorders, Samara Medical and Sanitary Unit № 5 of the Kirov Region (State Budgetary Healthcare Institution of the Samara Region). Changes in excitability and functional mobility of the sensorimotor system, development of vegetative-sensory polyneuropathy depending on the vibration disease type, severity, and the length of exposure to vibration at work are found in vibration disease patients.

Vibration disease from exposure to general vibration: methodology of diagnosis and place of electroneuromyography

2021 ◽  
pp. 7-16
Author(s):  
S.A. Babanov
Keyword(s):  
The State ◽  
Functional Mobility ◽  
Sensorimotor System ◽  
Vibration Disease ◽  
Regional Center ◽  
Neuromuscular Apparatus ◽  
Degrees Of Severity ◽  
Sensory Polyneuropathy

The article describes the features of the state of the neuromuscular apparatus in vibration diseases of various degrees of severity using electroneuromyographic research on the basis of the department of occupational Pathology of the regional center of Occupational Pathology of the Samara Medical and Sanitary Unit No. 5 of the Kirov district. It was found that patients with vibration disease are characterized by changes in the excitability and functional mobility of the sensorimotor system, the formation of vegetative-sensory polyneuropathy, depending on the severity of the vibration disease, the length of work in contact with vibration.

scholarly journals Prevalence of comorbid pathology in patients with vibration disease caused by exposure to local vibration

2020 ◽  
Vol 99 (10) ◽  
pp. 1079-1085
Author(s):  
Marina V. Kuleshova ◽  
Vladimir A. Pankov ◽  
Natalya V. Slivnitsyna
Keyword(s):  
Mastoid Process ◽  
Local Vibration ◽  
Work Related ◽  
Vibration Disease ◽  
Clinical Syndromes ◽  
Number Of Patients ◽  
Health Disorders ◽  
Relationship Of ◽  
The Relationship ◽  
Sensory Polyneuropathy

Introduction. Vibration as a factor of production is one of the leading that influences negatively on workers in various sectors of the economy. In available literature there no adequate information on the comorbid pathology in hand-arm vibration disease (HAVD) patients. The purpose of the study is to analyze the prevalence of somatic pathology in HAVD patients. Material and methods. The analysis of comorbidity of HAVD patients according in-depth medical data is carried out. The degree of relationship between work-related health disorders is assessed. The results are presented by average values, intensive and extensive indices, the relationship of work-related health disorders is confirmed by the calculation of the relative risk. Results. The main syndrome in the clinical picture of HAVD is autonomous-sensory polyneuropathy of the upper extremities, which is recorded in all patients, while some patients have a combination of two or more clinical syndromes of HAVD. A significant prevalence of diseases of the musculoskeletal and circulatory systems, eyes and its adnexa, ear and mastoid process, digestive, genitourinary system, and respiratory systems was revealed. Number of patients who have diseases of endocrine (up to 25.0%, p <0.01), digestive (up to 43.8%, p <0.01), urogenital (up to 37.5%, p <0.01), respiratory (up to 37.5%, p <0.05) and the circulatory (up to 52.9%, p <0.05) systems grows up with an increase of the experience dose of local vibration. Conclusion. The results of the study can serve as the basis for the implementation of measures for primary and secondary prevention of occupational diseases caused by local vibration, aimed at preventing the development of health disorders.

scholarly journals Mapping subregional types of population dynamics of Irkutsk region

2021 ◽  
Vol 27 (4) ◽  
pp. 361-372
Author(s):  
Nikolay Vorobyev ◽  
Alexander Vorobyev
Keyword(s):  
Population Dynamics ◽  
Temporal Dynamics ◽  
System Development ◽  
Rural Settlements ◽  
Population System ◽  
General Direction ◽  
Regional Center ◽  
Real Distribution ◽  
Irkutsk Region ◽  
Populated Region

In the article the results of research of specifics of digital mapping of spatial and temporal dynamics of the population in a sparsely populated region (on the example of Irkutsk region). The study area is mainly inhomogeneously populated, with a sparse network of settlements (mainly spatially contiguous). The exception is the south territory along the Trans-Siberian Railway. To identify subregional and local characteristics of distribution of the population, the famous dazimetric method of V.P. Semyonov-Tyan-Shansky was used (adjusted for the features of sparsely populated regions). The boundaries of the areal inhabited territory are defined by the method of spots with a buffer radius of 3 km from the borders of populated locality. The overlapping spots, form a solidly populated space, from which depart linear-band elements of settlement, formed on the base of settlements dislocated along the paths of old communications (rivers and roads). The article presents a geoinformation methodology for collecting and processing available statistical data about population movement. In contrast to usual mapping, the calculation of general population dynamics, growth component and subsequent mapping were implemented not in municipal districts, urban and rural settlements, but within localities and settlement areas formed by them, ignoring official boundaries. The mapping allowed to identify patterns and detailing of the dynamics of the population considering the features of real distribution of the population in Irkutsk region. There is a discrepancy between the tendencies of demographic and economic development. The growth of resource complex comes at the expense of the northern periphery of the region, and the general direction of the population system development—growth of demographic potential around the regional center in conditions of depopulation of the periphery. The experience of mapping subregional types of population dynamics in Irkutsk region can be used in mapping similar regions.

State of central hemodynamics and myocardial contractility in vibration disease

2020 ◽  
pp. 62-73
Author(s):  
Sergey Babanov
Keyword(s):  
Myocardial Contractility ◽  
Central Hemodynamics ◽  
Hemodynamic Changes ◽  
Vibration Disease ◽  
Regional Center ◽  
Severity Of The Disease ◽  
Degrees Of Severity

The article describes the peculiarities of Central hemodynamics and myocardial contractility in patients with vibration disease, various forms and degrees of severity with the help of echocardiography of the Department of pathology of the regional center of occupational pathology of SBME "Samara mediko-a sanitary part of № 5 of Kirov district". It was found that patients with vibration disease are characterized by the formation of a phase syndrome of myocardial hyperdynamics and a hyperkinetic variant of Central hemodynamics, while hemodynamic changes depend on the form of vibration disease, the severity of the disease, and the length of work in contact with vibration.

Intensity of muscular system growth in purebred and crossbred steers depending on functional loads

2020 ◽  
pp. 39-47
Author(s):  
I. Prokhorov ◽  
V. Lukyanov ◽  
O. Kalmykova
Keyword(s):  
Muscle Mass ◽  
Growth And Development ◽  
System Development ◽  
Relative Weight ◽  
Practical Application ◽  
Muscular System ◽  
Peripheral Part ◽  
Age Related ◽  
Axial Part ◽  
White Breed

The intensity of muscular system growth is largely determined by functional loads on it, and the frequency of growth and development of muscular system is associated with successive differentiations and is largely due to age-related changes in the level of sex steroids. Since crossbreeding is one of the effective methods of expanding the slaughter contingent of cattle the study of the intensity of muscular system growth of carcasses in purebred and crossbred animals is relevant and has indisputable practical application. The results of researches devoted to the study of the influence of functional loads on the intensity of growth and development of muscular system in steers of Blackand-White breed and its hybrids with Aberdeen-Angus and Charolais have been presented in the article. Muscle mass of carcasses was the biggest in Charolais crossbreds at the age of 12, 15 and 18 months it was, respectively, 172,4; 213,8 and 253,6 kg, which is significantly more than in herdmates of the maternal breed and Aberdeen-Angus crossbreds. The periodicity of muscular system development in the anatomical parts of carcasses has been found that largely due to functional loads as a result of which there is a redistribution of the muscular component in them. The biggest intensity of growth is typical for the muscle mass of the abdominal part, the least-for the muscles of the forearm and lower leg. A quarter of all muscles of carcasses accounted for the thigh in which the largest and most valuable in the nutrient framework are the biceps, quadriceps, semimembranosus, semitendinous muscles. The relative weight of the muscles located in the anatomical regions of the axial part of the skeleton with the age of animals has being increased and the muscles of the peripheral part of the skeleton-naturally has being decreased.

scholarly journals Identification of gene pathways altered by deletion of the androgen receptor specifically in mineralizing osteoblasts and osteocytes in mice

2012 ◽  
Vol 49 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Patricia K Russell ◽  
Michele V Clarke ◽  
Jarrod P Skinner ◽  
Tammy P S Pang ◽  
Jeffrey D Zajac ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Carbohydrate Metabolism ◽  
System Development ◽  
Biological Processes ◽  
Muscular System ◽  
Matrix Synthesis ◽  
Altered Expression ◽  
Androgen Action ◽  
Targeted Gene Expression ◽  
Osteoblast Genes

Androgens play a key role in skeletal growth and maintenance in males and can mediate their actions, at least in part, via the androgen receptor (AR) in osteoblasts. To investigate the mechanisms by which androgens exert their effects via the AR in mineralizing osteoblasts and osteocytes, we identified gene targets/pathways regulated by the AR using targeted gene expression and microarray approaches on bone isolated from mice in which the AR is specifically deleted in mineralizing osteoblasts and osteocytes (mOBL-ARKOs). Gene ontology mining indicated a number of biological processes to be affected in the bones of mOBL-ARKOs including skeletal and muscular system development and carbohydrate metabolism. All genes identified to have altered expression in the bones of mOBL-ARKOs were confirmed by Q-PCR for their androgen responsiveness in an androgen deprivation and replacement mouse model. The osteoblast genes Col1a1 and Bglap and the osteoclast genes Ctsk and RANKL (Tnfs11) were upregulated in the bones of mOBL-ARKOs, consistent with the increased matrix synthesis, mineralization, and bone resorption observed previously in these mice. Of significant interest, we identified genes involved in carbohydrate metabolism (adiponectin and Dpp4) and in growth and development (GH, Tgfb (Tgfb2), Wnt4) as potential targets of androgen action via the AR in mineralizing osteoblasts.

scholarly journals Application of ischemic preconditioning in the rehabilitation of miners suffered from the vibration disease

2021 ◽  
Vol 100 (7) ◽  
pp. 700-703
Author(s):  
Anastasia V. Yamshchikova ◽  
Ilya D. Martynov ◽  
Arnold N. Fleishman ◽  
Margarita O. Gidayatova
Keyword(s):  
Ischemic Preconditioning ◽  
Neuroprotective Effect ◽  
Upper Extremities ◽  
Control Group ◽  
Vibration Disease ◽  
Study Results ◽  
Sensory Responses ◽  
Functional Indices ◽  
Sensory Polyneuropathy

Introduction. Vibration disease is characterized by the early development of sensory polyneuropathy. Sensitive disorders significantly worsen the quality of life and increase the duration of the unemployable period of miners, which requires the search for new modern methods of correction and rehabilitation. Ischemic preconditioning is a promising direction in the treatment of occupationally caused polyneuropathies. However, its potential neuroprotective effect has not been sufficiently studied. The aim of the study was to evaluate the effectiveness of ischemic preconditioning of the upper extremities for the correction of sensory polyneuropathy manifestations in miners with vibration disease. Material and methods. Seventy-eight persons with a proven diagnosis of vibration disease were examined. According to a specially elaborated technique, the ischemic preconditioning of the upper extremities was performed in 46 patients who were included in the leading group; 32 patients made up the control group. The clinical and electroneuromyographic examination was carried out before the ischemic preconditioning procedure and on the 5th day of the study. Results. The initial clinical and neurophysiological indices in both groups did not differ statistically significant and indicated sensory polyneuropathy. After ischemic preconditioning, the subjects of the leading group showed an improvement in clinical and functional indices (reduction of numbness and paresthesia, improvement of vibration sensitivity, an increase in the sensory conduction velocity of impulse and the amplitudes of sensory responses) of the peripheral nerves of the upper extremities. In contrast, in the control group, there was no statistically significant change in objective indices. Conclusion. Ischemic preconditioning of the upper extremities is effective in the rehabilitation of miners with vibration disease, helps to reduce the manifestations of sensory polyneuropathy, sensitive disorders and normalize neurophysiological indices.

Cross-sectional TEM specimen preparation from magneto-optical disk by ultramicrotomy

1993 ◽  
Vol 51 ◽  
pp. 236-237
Author(s):  
F. Shaapur ◽  
M.J. Kim ◽  
Seh Kwang Lee ◽  
Soon Gwang Kim
Keyword(s):  
System Development ◽  
Thin Foil ◽  
Specimen Preparation ◽  
Material System ◽  
Cross Sectional ◽  
Protective Layers ◽  
New Material ◽  
Diamond Saw ◽  
Original Production ◽  
Thick Medium

TEM characterization and microanalysis of the recording media is crucial and complementary to new material system development as well as quality control applications. Due to the type of material generally used for supporting the medium, i.e., a polymer, conventional macro- and microthinning procedures for thin foil preparation are not applicable. Ultramicrotorny (UM) is a viable option and has been employed in previous similar studies. In this work UM has been used for preparation of XTEM samples from a magneto-optical (MO) recording medium in its original production format.The as-received material system consisted of a 4-layer, 2100 Å thick medium including a 300 Å TbFeCo layer enveloped by silicon nitride protective layers supported on a 1.2 mm thick × 135 mm (5.25 in.) diameter polycarbonate disk. Recording tracks had an approximate pitch of 1.6 μm separated by 800 Å deep peripheral grooves. Using a Buehler Isomet low-speed diamond saw, 1 mm wide and 20 mm long strips were cut out of the disk along the recording tracks.

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