scholarly journals Is inflammation a mechanism in arthrogenic TMJ Otalgia?

2001 ◽  
Vol 19 (4) ◽  
pp. 632-641
Author(s):  
Omar Franklin Molina ◽  
Raphael Navarro Aquilino ◽  
Rise Rank ◽  
Zeila Coelho Santos ◽  
Nayene Leocádia Manzutti Eid ◽  
...  
Keyword(s):  
Trend Analysis ◽  
Clinical Examination ◽  
Control Groups ◽  
Chi Square ◽  
Disk Displacement ◽  
Internal Joint ◽  
The Difference ◽  
Biomechanical Tests

Objective. To test the hypothesis that otalgia occurs frequently in CMDs patients and increases with the severity of Temporomandibular internal derangements (TMJ-IDs). Method. 221 CMDs patients and two control groups were evaluated. We used clinical examination, questionnaires, biomechanical tests and established criteria for TMJ-IDs. Individuals were allocated to TMJ-ID groups to compare otalgia frequencies. Following assessment of frequency of otalgia in the CMD group, individuals were allocated to TMJ-ID subgroups with capsulitis, retrodiskal pain, disk-attachment pain, arthralgia and osteoarthritis (OA). Results. Otalgia frequency was higher in CMDs patients than in the two control groups and the difference was statistically significant (p<0.0001 and p><0.003). Otalgia frequency increased with the severity of TMJ-IDs (Chi-square trend analysis p><0.0001). Frequency of otalgia was higher in the disk attachment pain, arthralgia and osteoarthritis subgroups. Conclusion. The frequency of otalgia was higher in CMDs and increases with the severity of TMJ-ID. Those presenting more severe TMJ-IDs demonstrated higher frequencies of otalgia. The results of this study suggest a relationship between disk displacement, stages of internal joint derangements, pain and TMJ otalgia.>

Depression, pain, and site:

1999 ◽  
Vol 15 (1) ◽  
pp. 10-17
Author(s):  
Molina Omar Franklin ◽  
Tavares Gimenes Pablo ◽  
Aquilino Raphael ◽  
Rank Rise ◽  
Coelho Santos Zeila ◽  
...  
Keyword(s):  
Visual Analogue Scale ◽  
Beck Depression Inventory ◽  
Temporomandibular Disorders ◽  
Analogue Scale ◽  
Epidemiological Data ◽  
Depression Severity ◽  
Internal Joint ◽  
The Difference ◽  
Biomechanical Tests

Objective: To assess the level of depression, severity of pain and pain in single/multiple sites in patients with different severity of bruxing behavior and Temporomandibular Disorders (TMDs). Methods: We evaluated 131 patients with bruxism and TMDs: 20 patients with mild bruxism, 42 patients with moderate bruxism, 45 patients with severe bruxism and 24 patients with extreme bruxism. We used the Beck Depression Inventory (BDI), clinical examination, a questionnaire of clinical epidemiological data, criteria for TMDs and bruxism, palpation of muscles and joints, the Visual Analogue Scale for pain, classification of the occlusion and biomechanical tests to assess for internal joint derangements. Results: The level of depression increased from the mild, to the moderate, severe and extreme bruxing behavior groups, but the difference was significant only from the mild to the extreme group (p<0.001). Pain levels increased from the mild and moderate to the severe and extreme subgroups, but were not statistically significant. Mean number of pain sites increased from the mild, to the moderate, severe and extreme subgroup and the difference was extremely significant (p<0.0001). Conclusion: Levels of depression, severity of pain and pain sites increased with severity of bruxing behavior. A higher number of pain sites with more severe bruxism indicates somatization in bruxers, but a further study using the same protocol and a psychological test for somatization would be indicated to further substantiate these findings.

Seroprevalence of Helicobacter pylori infection in patients with chronic nonspecific pharyngitis: preliminary study

2007 ◽  
Vol 122 (1) ◽  
pp. 61-64 ◽  
Author(s):  
İ Aladag ◽  
Y Bulut ◽  
M Guven ◽  
A Eyibilen ◽  
K Yelken
Keyword(s):  
Helicobacter Pylori ◽  
Treatment Strategies ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Control Groups ◽  
Chi Square ◽  
Control Subjects ◽  
The Difference ◽  
H Pylori ◽  
And Control

AbstractBackground and objectives:Chronic nonspecific pharyngitis is a chronic inflammation of the pharynx. It is found worldwide, and treatment is difficult. The underlying aetiopathogenesis is still controversial. The aim of this study was to investigate Helicobacter pylori seroprevalence in chronic nonspecific pharyngitis patients without other possible causative factors for chronic pharyngeal irritation and without H pylori gastric mucosal infection.Materials and methods:Forty-one patients with symptoms of chronic nonspecific pharyngitis and 30 healthy control subjects were enrolled in this prospective, controlled, clinical study. In both study and control groups, selected patients were shown to have gastric mucosa uninfected by H pylori, as demonstrated by the 14C-urea breath test. Comprehensive otorhinolaryngological examination did not elicit any factor contributing to the chronic pharyngeal complaint. Serum H pylori immunoglobulin G antibody titres were assayed using serum enzyme-linked immunosorbent assay. The difference between the study and control groups was analysed by the chi-square test (the likelihood ratio was used).Results:Thirty-two of the 41 patients (78 per cent) and 14 of the 30 control subjects (46.7 per cent) were found to be H pylori positive. Patients with chronic nonspecific pharyngitis were found to have a significantly higher rate of H pylori seropositivity than the control group (p = 0.016).Conclusion:These data may be important in developing future treatment strategies for chronic nonspecific pharyngitis.

scholarly journals Tmj Arthralgia: A Rarely Described Internal Joint Derangement And Characterization Regarding Factors Of Age , Pain Description, And Prevalence In Craniomandibular Disorders Individuals (CMDs)

2017 ◽  
Vol 5 (14) ◽  
pp. 71-81
Author(s):  
Omar Franklin Molina ◽  
Raphael Navarro Aquilino ◽  
Ed Wilson César ◽  
Sérgio Elias Cury ◽  
Ricardo Léllis Marçal ◽  
...  
Keyword(s):  
Diagnostic Tests ◽  
Severe Pain ◽  
Craniomandibular Disorders ◽  
Control Groups ◽  
Burning Pain ◽  
Chronic Disorder ◽  
Internal Joint ◽  
History Of ◽  
The Difference ◽  
Experimental Group

Aims: Characterize Craniomandibular Disorders (CMDs) and arthralgia individuals regarding factors of age, joint noises, frequency of burning pain and severity of pain. Material and Methods: 25 CMD and arthralgia patients, 39 CMDs and capsulitis patients were retrieved from a large sample of  CMD patients and were compared with a control Non CMD group. History of sign and symptoms, questionnaires, clinical examination, description of pain, diagnostic tests and criteria for CMDs were used. Results: Mean age in the experimental (CMD+arthralgia group) was about 40.2 years old. The frequency of joint noises was about 72%   in the CMDs+arthralgia group as compared to the other two control groups (56.4% and 40.6%) . Bilateral reciprocal click was also more frequently in the experimental group than in the controls and the difference was statistically significant. The frequency of  severe pain was much higher in the  CMD+arthralgia than in the CMD+capsulitis group (80% and 10.2% respectively). The description of burning pain was observed  exclusively  in the CMD+arthralgia group. Finally, the frequency of pain increased from the Non CMD to the CMD+capsulitis and to the CMD+arthralgia group. Conclusions: The results of this study indicate that arthralgia is a more chronic disorder characterized  by burning pain, more severe pain and higher  frequency of  joint noises, specifically unilateral reciprocal click.

scholarly journals Tmj Arthralgia: A Rarely Described Internal Joint Derangement And Characterization Regarding Factors Of Age , Pain Description, And Prevalence In Craniomandibular Disorders Individuals (CMDs)

2017 ◽  
Vol 5 (14) ◽  
pp. 71
Author(s):  
Omar Franklin Molina ◽  
Raphael Navarro Aquilino ◽  
Ed Wilson César ◽  
Sérgio Elias Cury ◽  
Ricardo Léllis Marçal ◽  
...  
Keyword(s):  
Diagnostic Tests ◽  
Severe Pain ◽  
Craniomandibular Disorders ◽  
Control Groups ◽  
Burning Pain ◽  
Chronic Disorder ◽  
Internal Joint ◽  
History Of ◽  
The Difference ◽  
Experimental Group

Aims: Characterize Craniomandibular Disorders (CMDs) and arthralgia individuals regarding factors of age, joint noises, frequency of burning pain and severity of pain. Material and Methods: 25 CMD and arthralgia patients, 39 CMDs and capsulitis patients were retrieved from a large sample of  CMD patients and were compared with a control Non CMD group. History of sign and symptoms, questionnaires, clinical examination, description of pain, diagnostic tests and criteria for CMDs were used. Results: Mean age in the experimental (CMD+arthralgia group) was about 40.2 years old. The frequency of joint noises was about 72%   in the CMDs+arthralgia group as compared to the other two control groups (56.4% and 40.6%) . Bilateral reciprocal click was also more frequently in the experimental group than in the controls and the difference was statistically significant. The frequency of  severe pain was much higher in the  CMD+arthralgia than in the CMD+capsulitis group (80% and 10.2% respectively). The description of burning pain was observed  exclusively  in the CMD+arthralgia group. Finally, the frequency of pain increased from the Non CMD to the CMD+capsulitis and to the CMD+arthralgia group. Conclusions: The results of this study indicate that arthralgia is a more chronic disorder characterized  by burning pain, more severe pain and higher  frequency of  joint noises, specifically unilateral reciprocal click.

scholarly journals Depression, pain, and site

2019 ◽  
Vol 15 (1) ◽  
pp. 10-17
Author(s):  
Molina Omar Franklin ◽  
Tavares Gimenes Pablo ◽  
Aquilino Raphael ◽  
Rank Rise ◽  
Zeila Santos Coelho ◽  
...  
Keyword(s):  
Visual Analogue Scale ◽  
Beck Depression Inventory ◽  
Temporomandibular Disorders ◽  
Analogue Scale ◽  
Epidemiological Data ◽  
Depression Severity ◽  
Internal Joint ◽  
The Difference ◽  
Biomechanical Tests

Objetivo: Avaliar o nível de depressão, severidade da dor e dor em locais únicos e múltiplos em pacientes com diversos graus de bruxismo e Distúrbios Temporomandibulares (DTMs). Método: Nós avaliamos 131 pacientes com bruxismo e DTMs: 20 pacientes com bruxismo leve, 42 com bruxismo moderado, 45 com bruxismo severo e 24 com bruxismo extremo. Nos usamos o Questionário de Depressão de Beck, exame clínico, um questionário para dados epidemiológicos, critérios para Distúrbios Temporomandibulares e bruxismo, palpação dos músculos e articulações, a escala análoga visual para avaliar dor, classificação da oclusão e testes biomecânicos para avaliar distúrbios internos articulares. Resultados: O nível de depressão aumentou do grupo leve para o moderado, severo e extremo de pacientes com bruxismo, mas a diferença foi significante somente do grupo leve para o extremo (p<0.001). O nível de dor aumentou dos grupos leve e moderado para o severo e extremo, mas a diferença não foi significante. O número médio de locais com dor aumentou do grupo leve para os grupos moderado, severo e extremo e a diferença foi estatística e extremamente significante (p><0.0001). Conclusão: Os níveis de depressão, severidade da dor e locais com dor aumentaram com a severidade do bruxismo. Um número maior de locais com dor foi observado a medida que aumentou a severidade do bruxismo. Isto pode indicar somatização nesses pacientes, mas um estudo adicional usando o mesmo protocolo e um teste psicológico para somatização seria indicado para substanciar adicionalmente estes achados>Objective: To assess the level of depression, severity of pain and pain in single/multiple sites in patients with different severity of bruxing behavior and Temporomandibular Disorders (TMDs). Methods: We evaluated 131 patients with bruxism and TMDs: 20 patients with mild bruxism, 42 patients with moderate bruxism, 45 patients with severe bruxism and 24 patients with extreme bruxism. We used the Beck Depression Inventory (BDI), clinical examination, a questionnaire of clinical epidemiological data, criteria for TMDs and bruxism, palpation of muscles and joints, the Visual Analogue Scale for pain, classification of the occlusion and biomechanical tests to assess for internal joint derangements. Results: The level of depression increased from the mild, to the moderate, severe and extreme bruxing behavior groups, but the difference was significant only from the mild to the extreme group (p <0.001). Pain levels increased from the mild and moderate to the severe and extreme subgroups, but were not statistically significant. Mean number of pain sites increased from the mild, to the moderate, severe and extreme subgroup and the difference was extremely significant (p><0.0001). Conclusion: Levels of depression, severity of pain and pain sites increased with severity of bruxing behavior. A higher number of pain sites with more severe bruxism indicates somatization in bruxers, but a further study using the same protocol and a psychological test for somatization would be indicated to further substantiate these findings.>

Relationship between total plasma homocysteine and the risk of aneurysms – a meta-analysis

VASA ◽  
2020 ◽  
pp. 1-6
Author(s):  
Hanji Zhang ◽  
Dexin Yin ◽  
Yue Zhao ◽  
Yezhou Li ◽  
Dejiang Yao ◽  
...  
Keyword(s):  
Large Scale ◽  
Meta Analysis ◽  
Single Species ◽  
Total Plasma ◽  
Control Groups ◽  
Randomized Controlled ◽  
Randomized Controlled Studies ◽  
The Difference ◽  
The Relationship ◽  
Healthy Participants

Summary: Our meta-analysis focused on the relationship between homocysteine (Hcy) level and the incidence of aneurysms and looked at the relationship between smoking, hypertension and aneurysms. A systematic literature search of Pubmed, Web of Science, and Embase databases (up to March 31, 2020) resulted in the identification of 19 studies, including 2,629 aneurysm patients and 6,497 healthy participants. Combined analysis of the included studies showed that number of smoking, hypertension and hyperhomocysteinemia (HHcy) in aneurysm patients was higher than that in the control groups, and the total plasma Hcy level in aneurysm patients was also higher. These findings suggest that smoking, hypertension and HHcy may be risk factors for the development and progression of aneurysms. Although the heterogeneity of meta-analysis was significant, it was found that the heterogeneity might come from the difference between race and disease species through subgroup analysis. Large-scale randomized controlled studies of single species and single disease species are needed in the future to supplement the accuracy of the results.

Efektivitas Short Message Service Reminderterhadap Kepatuhan Konsumsi Tablet Besi pada Wanita Hamil

1970 ◽  
Vol 2 (3) ◽  
Author(s):  
Ermiati E ◽  
Imas Rafiyah ◽  
Devi Kusnanti
Keyword(s):  
Short Message Service ◽  
Self Report ◽  
Control Group ◽  
Short Message ◽  
Control Groups ◽  
Chi Square ◽  
Purposive Sampling ◽  
Message Service ◽  
Sms Reminder ◽  
Expectant Mothers

Anemia merupakan salah satu penyebab terjadinya perdarahan dan bisa mengakibatkan kematian pada ibu hamil. Suplementasi besi merupakan program pemerintah dalam mengatasi anemia pada wanita hamil dan beberapa wanita hamil masih ada yang belum patuh dalam mengkonsumsi tablet besi. Oleh karena itu, diperlukan sebuah metode yang bisa meningkatkan kepatuhan wanita hamil dalam mengonsumsi tablet besi yaitu dengan short message service (SMS) reminder. Penelitian ini bertujuan untuk mengidentifikasi efektivitas SMS reminderterhadap kepatuhan konsumsi tablet besi pada ibu hamil di (unit pelayanan terpadu) UPT Puskesmas Cibuntu Kota Bandung. Rancangan penelitian quasi experimentaldengan desain posttest-only with control group designdengan teknik pengambilan sampel yang digunakan adalah purposive sampling. Penelitian ini dilaksanakan dari bulan April–Mei tahun 2014 di Puskesmas X Kota Bandung. Sampel berjumlah 40 orang wanita hamil yang tidak patuh dalam mengonsumsi tablet besi yang dibagi menjadi 20 kelompok intervensi dan 20 kelompok kontrol. Data diperoleh melalui kuesioner dalam bentuk self report.Analisis data yang digunakan adalah analisis deskriptif dan uji chi square. Hasil penelitian menunjukkan sebagian besar kelompok intervensi 17 orang (85%) patuh dan sebagian besar kelompok kontrol 16 orang (80%) tidak patuh. Hasil analisis dengan menggunakan chi squaredidapatkan p(0.000) dengan taraf signifikan <0.05 sehingga dapat disimpulkan bahwa SMS reminder efektif terhadap kepatuhan konsumsi tablet besi pada wanita hamil dan bisa dijadikan bahan pertimbangan bagi pihak Puskesmas untuk menjalin kerjasama dengan pihak provideratau mengajukan dana ke Dinas Kesehatan untuk mengaktifkan SMS reminderdi Puskesmas.Kata kunci: Kepatuhan, SMS reminder,tablet besi, wanita hamil AbstractAnemia is one of the leading causes of hemorrhage during pregnancy, and it can cause death to expectant mothers. Iron supplementation is a government program to overcome anemia among expectant mothers, and some of the expectant mothers still do not obediently consume iron tablets. Therefore, to increase the obedience of the expectant mothers on consuming the iron tablets, SMS reminder is the appropriate method needed. This research aims to identify the effectiveness of SMS reminder to the obedience of iron tablets consumption among expectant mothers at UPT Puskesmas Cibuntu , Bandung. The research employed quasi-experimental design with posttest-only control group design using purposive sampling technique. The research was held on April–May 2014 at UPT Puskesmas Cibuntu, Bandung. Forty expectant mothers consuming iron tablets disobediently divided into 20 intervention groups and 20 control groups were taken as the samples. Questionnaire in form of self report was used to obtain data. In addition, descriptive analysis and chi square test were applied to analyze the data. The result of the research showed that 17 persons (85%) of intervention groups were mostly obedient, and 16 persons (80%) of control groups were mostly disobedient. From the analysis using chi square, it was found the difference of the obedience of iron tablets consumption after SMS reminder (p=0.00) had been delivered with significant level <0.05. Based on the result of this research, SMS reminder had an effective impact toward the obedience of iron tablets consumption among the expectant mothers. The result will be a good consideration for Puskesmas to cooperate with provider or proposed some funds to Dinas Kesehatan to activate SMS reminder.Key words:Expectant mothers, obedience, SMS reminder, iron tablets

386 An Exploratory Study of Bedtime Procrastination and Emotional Regulation Strategies in Insomnia compared to healthy individuals

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A153-A153
Author(s):  
Goeun Kim ◽  
Hyojin Nam ◽  
Huisu Jeon ◽  
Sooyeon Suh
Keyword(s):  
Emotional Regulation ◽  
Severity Index ◽  
Ministry Of Education ◽  
Chi Square ◽  
Healthy Group ◽  
Significant Difference ◽  
Regulation Strategies ◽  
The Difference ◽  
The Republic ◽  
Bedtime Procrastination

Abstract Introduction Bedtime Procrastination (BP) is defined as the behavior of voluntarily delaying going to bed, without having external reasons for doing so. Recent research on procrastination behavior suggests that when negative emotions are elevated, procrastination behaviors can be triggered in order to find pleasure to avoid and alleviate them. Procrastination can also occur when there is difficulty regulating emotions. In addition, the reason for bedtime procrastination may be different depending on whether the individuals present with insomnia. According to previous studies, patients with insomnia may exhibit more pronounced negative avoidance of bedtime due to prolonged sleeplessness. Therefore, this study compared the difference between of the bedtime procrastination and the emotional regulation strategies between the insomnia group and the healthy group. Methods This study was conducted in 582 adults (mean age 23.06 ±2.16 years), 81.6% females. Individuals scoring higher than 15 on the Insomnia Severity Index (ISI) were classified into the insomnia group (n=375), and those less than 15 were classified into the healthy group (n=207). Participants completed the Bedtime Procrastination Scale (BPS), Emotional Regulation Strategies Checklist. Data was analyzed using descriptive statistics, chi square test, and independent t tests. Results The insomnia group had significantly higher bedtime procrastination scores than the healthy group (t=-6.241, p&lt;.001), and also the avoidant/distractive regulation style score was significantly higher (t=-1.969, p&lt;.05). In addition, the score of active regulation style was significantly lower in the insomnia group than in the healthy group (t=3.050, p&lt;.01). There was no significant difference between the two groups in the support-seeking regulation style. Conclusion Based on these results, it was confirmed that there was a difference in the bedtime procrastination and the emotional regulation strategies between the insomnia group and the healthy group. Support (if any) This work was supported by the Ministry of Education of the Republic of Korea and the National Research Foundation of Korea(NRF-2018S1A5A8026807)

scholarly journals Premedication Does Not Influence the Incidence of Infliximab Infusion Reactions in Pediatric Patients with Inflammatory Bowel Disease—A Single Center Case–Control Study

2021 ◽  
Vol 10 (14) ◽  
pp. 3177
Author(s):  
Edyta Szymanska ◽  
Maciej Dadalski ◽  
Joanna Sieczkowska-Golub ◽  
Dorota Jarzebicka ◽  
Monika Meglicka ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Pediatric Patients ◽  
Case Control Study ◽  
Case Control ◽  
Chi Square ◽  
Infusion Reactions ◽  
Inflammatory Bowel ◽  
The Difference ◽  
Control Study

Background: Infusion reactions (IRs) are the most common adverse events (AEs) of infliximab (IFX) treatment in patients with inflammatory bowel disease (IBD). Prophylactic premedication (PM) with corticosteroids or antihistamines prior to IFX infusions has been used in clinical practice, but its efficacy is not known. The aim of this study was to assess the influence of steroid PM on IR incidence in pediatric patients with IBD receiving IFX. Methods: We performed a case–control study that included pediatric patients with IBD receiving IFX. Patients were divided into four subgroups according to the agent and PM they received: Remicade (original drug) + PM, and two biosimilars—Reshma +/− PM, and Flixabi—PM. At our site, until 2018, PM with steroids was used as a part of standard IFX infusion (PM+); however, since then, this method has no longer been administered (PM−). IRs were divided into mild/severe reactions. Differences between subgroups were assessed with the appropriate chi-square test. Multivariate logistic regression was used to assess associations between PM and IR incidence, correcting for co-medication usage. Results: There were 105 children (55 PM+, 44 male, mean age 15 years) included in the study who received 1276 infusions. There was no difference between the PM+ and PM− subgroups, either in incidence of IR (18.2% vs. 16.0% of patients, p > 0.05) or in percentage of infusions followed by IR (2.02% vs. 1.02% of infusions, p > 0.5). The OR of developing IR when using PM was 0.34, and the difference in IRs ratio in PM+ and PM− patients was not statistically significant (95% CI, 0.034–1.9). There were 11/18 (61.1%) severe IRs (anaphylactic shock) reported in all patients (both PM+ and PM−). Conclusion: At our site, the incidence of IR was low, and PM did not decrease the incidence of IR in pediatric patients with IBD receiving IFX. These results indicate that PM with steroids should not be a standard part of IFX infusion to prevent IR.

scholarly journals Instructional Efficacy of Portfolio for Assessing Iranian EFL Learners’ Speaking Ability

2016 ◽  
Vol 9 (3) ◽  
pp. 102
Author(s):  
Mahshad Safari ◽  
Mansour Koosha
Keyword(s):  
Alternative Form ◽  
Control Groups ◽  
Self Assessment ◽  
Chi Square ◽  
Efl Learners ◽  
Instructional Efficacy ◽  
Advanced Students ◽  
Advanced Control ◽  
Speaking Skill ◽  
Advanced Proficiency

<p>Regarding the fundamental role of speaking in language skills, this study intended to investigate the effects of speaking portfolio as an alternative form of assessment for assessing Iranian EFL learners’ speaking ability at the intermediate and advanced proficiency levels and also its impact on their attitudes. Accordingly, from the population of 72 students studying at Kowsar Language Institute in Esfahan, a sample of 64 male and female intermediate and advanced students were randomly selected based on their scores on an OPT test and they were assigned to 4 groups: intermediate and advanced experimental groups and intermediate and advanced control groups. In order to collect the data, a pretest and a posttest as well as a questionnaire were employed. To analyze the data, an ANOVA and a series of Chi-square were run in the study and the findings indicated that the experimental groups using speaking portfolios performed better than the control groups in terms of speaking ability. Moreover, the result shed light on the advantages of speaking portfolios such as self-assessment, peer-feedback, and improvement of speaking skill. This study provides instructors, administrators, and test developers with alternative ways to improve and assess speaking skill through speaking portfolios.</p>

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