scholarly journals Piezoelectric Peptide and Metabolite Materials

Research ◽  
2019 ◽  
Vol 2019 ◽  
pp. 1-13 ◽  
Author(s):  
Hui Yuan ◽  
Peipei Han ◽  
Kai Tao ◽  
Shuhai Liu ◽  
Ehud Gazit ◽  
...  

Piezoelectric materials are important for many physical and electronic devices. Although many piezoelectric ceramics exhibit good piezoelectricity, they often show poor compatibility with biological systems that limits their biomedical applications. Piezoelectric peptide and metabolite materials benefit from their intrinsic biocompatibility, degradability, and convenient biofunctionalization and are promising candidates for biological and medical applications. Herein, we provide an account of the recent progress of research works on piezoelectric peptide and metabolite materials. This review focuses on the growth mechanism of peptide and metabolite micro- and nanomaterials. The influence of self-assembly processes on their piezoelectricity is discussed. Peptide and metabolite materials demonstrate not only outstanding piezoelectric properties but also unique electronic, optical, and physical properties, enabling their applications in nanogenerators, sensors, and optical waveguiding devices.

2018 ◽  
Vol 400 (1) ◽  
pp. 39-62 ◽  
Author(s):  
Nagendra Kumar Kaushik ◽  
Bhagirath Ghimire ◽  
Ying Li ◽  
Manish Adhikari ◽  
Mayura Veerana ◽  
...  

Abstract Non-thermal atmospheric pressure plasma has been proposed as a new tool for various biological and medical applications. Plasma in close proximity to cell culture media or water creates reactive oxygen and nitrogen species containing solutions known as plasma-activated media (PAM) or plasma-activated water (PAW) – the latter even displays acidification. These plasma-treated solutions remain stable for several days with respect to the storage temperature. Recently, PAM and PAW have been widely studied for many biomedical applications. Here, we reviewed promising reports demonstrating plasma-liquid interaction chemistry and the application of PAM or PAW as an anti-cancer, anti-metastatic, antimicrobial, regenerative medicine for blood coagulation and even as a dental treatment agent. We also discuss the role of PAM on cancer initiation cells (spheroids or cancer stem cells), on the epithelial mesenchymal transition (EMT), and when used for metastasis inhibition considering its anticancer effects. The roles of PAW in controlling plant disease, seed decontamination, seed germination and plant growth are also considered in this review. Finally, we emphasize the future prospects of PAM, PAW or plasma-activated solutions in biomedical applications with a discussion of the mechanisms and the stability and safety issues in relation to humans.


2018 ◽  
Vol 29 (10) ◽  
pp. 2105-2121 ◽  
Author(s):  
Mohammed Salim ◽  
Dhia Salim ◽  
Davannendran Chandran ◽  
Hakim S Aljibori ◽  
A Sh Kherbeet

The piezoelectric devices, based on micro–nano electromechanical systems, are well known nowadays due to their small features, ability for integration with the integrated circuit in a single platform, robust, and easily fabricated in bulk. The enhanced performance of piezoelectric systems, which is soft, flexible, and stretchable made them have unique opportunities to be used in bio-integrated applications as nanodevices for energy harvesting, sensing, actuation, and cell stimulation. The selection of optimized configurations depends on thin geometries, neutral mechanical plane construction, and controlled buckling, while inorganic piezoelectric materials are preferred for interfaces with human bodies. The key considerations in designs, the analytical derivations for voltage and displacement, and the effect of the voltmeter resistance on the voltage measurements are presented. Devices for energy harvesting from natural motions of internal organs, sensors, and actuators for medical applications are reviewed. The PMN-PT energy harvester that produced current of 0.22 mA is higher than the rest of the discussed harvesters. Thus, it is more suitable to be used as a sufficient source of energy in biomedical applications. The use of piezoelectric nanowires and ribbons proved successful, and the dual features of device (sensor and actuator) seem advantageous.


Author(s):  
Sunija Sukumaran ◽  
Samir Chatbouri ◽  
Didier Rouxel ◽  
Etienne Tisserand ◽  
Frédéric Thiebaud ◽  
...  

Energy harvesting is one of the most promising research areas to produce sustainable power sources from the ambient environment. Which found applications to attain the extensive lifetime self-powered operations of various devices such as MEMS wireless sensors, medical implants and wearable electronic devices. Piezoelectric nanogenerators can efficiently convert the vastly available mechanical energy into electrical energy to meet the requirements of low-powered electronic devices. Among the piezoelectric materials, poly (vinylidene fluoride) (PVDF) and its copolymers are extensively studied for the development of energy harvesting devices. Due to the outstanding properties such as high flexibility, ease of processing, long-term stability, biocompatibility makes them a promising candidate for piezoelectric generators. Nevertheless, compared to piezoceramic materials, PVDF based generators produce lower piezoresponse. Over the last decades, tremendous research activities have been reported to endorse the performance of PVDF based energy harvesters. This review article mainly focused on the recent progress in the performance improvement with processing methods, piezoelectric materials, different filler loading. The new developments and design structures will lead to an increase in piezoelectricity, alignment of dipoles, dielectric properties and subsequently enhance the output performance of the device. Electronic circuits play a vital role in energy harvesting to efficiently collect the developed charge from the device. Here, we have proposed a detailed description of the electronic circuits. Also, in the application part deals with the recent progress in flexible, biomedical and hybrid generators based on PVDF polymers.


Nano LIFE ◽  
2015 ◽  
Vol 05 (02) ◽  
pp. 1542002 ◽  
Author(s):  
Xiao Gong

Layer-by-layer (LbL) self-assembly has attracted extensive attention for its simplicity and versatility. Self-assembly has many potential applications, among which biomedical applications is especially important because it can be used as a means of generating drug delivery and biomedical materials. Based on this, most recent progress in the field of self-assembly technique for drug delivery and biomedical material applications are summarized in this mini review. The remaining challenges are also mentioned.


Author(s):  
Yushun Zeng ◽  
Laiming Jiang ◽  
Qingqing He ◽  
Robert Wodnicki ◽  
Yang Yang ◽  
...  

Nanomedicine ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. 139-163
Author(s):  
Sonika Chibh ◽  
Jibanananda Mishra ◽  
Avneet Kour ◽  
Virander S Chauhan ◽  
Jiban J Panda

Molecular self-assembly is a widespread natural phenomenon and has inspired several researchers to synthesize a compendium of nano/microstructures with widespread applications. Biomolecules like proteins, peptides and lipids are used as building blocks to fabricate various nanomaterials. Supramolecular peptide self-assembly continue to play a significant role in forming diverse nanostructures with numerous biomedical applications; however, dipeptides offer distinctive supremacy in their ability to self-assemble and produce a variety of nanostructures. Though several reviews have articulated the progress in the field of longer peptides or polymers and their self-assembling behavior, there is a paucity of reviews or literature covering the emerging field of dipeptide-based nanostructures. In this review, our goal is to present the recent advancements in dipeptide-based nanostructures with their potential applications.


2019 ◽  
Vol 12 (05) ◽  
pp. 1950070 ◽  
Author(s):  
Zhonghua Dai ◽  
Dingyan Li ◽  
Jinglong Xie ◽  
Weiguo Liu ◽  
Shaobo Ge ◽  
...  

High-performance lead-free piezoelectric materials are environmentally friendly and in great demand for electronic devices. In this study, the phase diagram and properties of Hf, Ca co-doped BaTiO3 (BHT-BCT) were investigated. A triple-point morphotropic phase boundary separating the rhombohedral, tetragonal and cubic phases for the (1-[Formula: see text])Ba(Ti0.85Hf0.15)O3-[Formula: see text](Ba0.7Ca0.3)TiO3 system exited at [Formula: see text] High piezoelectric properties with piezoelectric coefficients [Formula: see text] (572pC/N) and Curie temperature [Formula: see text] (90∘C) of 0.55Ba(Ti0.85Hf0.15)O3-0.45(Ba0.7Ca0.3)TiO3 are achieved in the BaTiO3-based ceramics.


2021 ◽  
Author(s):  
Marissa Morales-Moctezuma ◽  
Sebastian G Spain

Nanogels have emerged as innovative platforms for numerous biomedical applications including gene and drug delivery, biosensors, imaging, and tissue engineering. Polymerisation-induced thermal self-assembly (PITSA) has been shown to be suitable...


Author(s):  
Deming He ◽  
Minmin Yan ◽  
Pengjuan Sun ◽  
Yuanqiang Sun ◽  
Lingbo Qu ◽  
...  

2021 ◽  
Author(s):  
Yu Fu ◽  
Lei Yang ◽  
Jianhua Zhang ◽  
Junfei Hu ◽  
Gaigai Duan ◽  
...  

This review focuses on the recent progress in polydopamine antibacterial materials, including their structural and functional features, preparation strategies, antibacterial mechanisms, and their biomedical applications.


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