scholarly journals Temporal and Geographical Trends of Incidence of Thyroid Cancer in Golestan, Iran, 2004-2013

2021 ◽  
Vol 24 (1) ◽  
pp. 1-6
Author(s):  
Fatemeh Salamat ◽  
Ali Aryannia ◽  
Siamak Rajaei ◽  
Mohammad Naeimi-Tabiei ◽  
Reza Afghani ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Population Based ◽  
Incidence Rates ◽  
Common Type ◽  
Cancer Data ◽  
Significant Difference ◽  
Golestan Province ◽  
Males And Females ◽  
The Mean ◽  
Increasing Trends

Background: Thyroid cancer is the most common type of endocrine cancer. We aimed to determine the incidence rates of thyroid cancer across a 10-year period (2004-2013) in Golestan, Iran. Methods: We obtained the thyroid cancer data from Golestan Population-Based Cancer Registry (GPCR). Age-standardized incidence rates (ASR) were calculated and reported per 100000 person-years. The Joinpoint software was used to assess time trends, and average annual percent changes (AAPCs) and their corresponding 95% confidence intervals (CIs) were reported. Results: Of 326 registered patients, 83 (25.5%) were men and 243 (74.5%) were women. The mean age was 51.3 and 42.6 years for males and females, respectively. Overall, the ASR of thyroid cancer was 2.2 per 100000 person-year (AAPC = 2.76; 95% CI: -3.68 to 9.64). The test of co-incidence showed a statistically significant difference in the incidence of thyroid cancer between men (1.3) and women (3.2) (P < 0.001). According to our results, the ASR of thyroid cancer in western parts of Golestan is higher, including Gorgan and Aliabad cities. Conclusion: Increasing trends in incidence rates of thyroid cancer were found in the Golestan province during the study period, especially in women. We found significantly higher rates of thyroid cancer in women. Geographical diversities were seen in incidence rates of thyroid cancer in the Golestan province. Our results may be helpful for designing further researches to investigate the epidemiological aspects of thyroid cancer in the Golestan province.

scholarly journals Western Honduras Copán Population–Based Cancer Registry: Initial Estimates and a Model for Rural Central America

2021 ◽  
pp. 1694-1702
Author(s):  
Dalton Argean Norwood ◽  
Eleazar Enrique Montalvan-Sanchez ◽  
Juan E. Corral ◽  
Dagoberto Estévez-Ordoñez ◽  
Andrea A. Paredes ◽  
...  
Keyword(s):  
Central America ◽  
Cancer Control ◽  
Cancer Registries ◽  
Population Based ◽  
Incidence Rates ◽  
Western Hemisphere ◽  
Ancillary Data ◽  
Web Based ◽  
Cancer Data ◽  
Males And Females

PURPOSE Population-based cancer registries (PBCRs) are critical for national cancer control planning, yet few low- and middle-income countries (LMICs) have quality PBCRs. The Central America Four region represents the principal LMIC region in the Western hemisphere. We describe the establishment of a PBCR in rural Western Honduras with first estimates for the 2013-2017 period. METHODS The Western Honduras PBCR was established through a collaboration of academic institutions and the Honduras Ministry of Health for collection of incident cancer data from public and private health services. Data were recorded using the Research Electronic Data Capture (REDCap) web-based platform with data monitoring and quality checks. Crude and age-standardized rates (ASRs) were calculated at the regional level, following WHO methodology. RESULTS The web-based platform for data collection, available ancillary data services (eg, endoscopy), and technical support from international centers (United States and Colombia) were instrumental for quality control. Crude cancer incidence rates were 112.2, 69.8, and 154.6 per 100,000 habitants overall, males, and females, respectively (excluding nonmelanoma skin cancer). The adjusted ASRs were 84.2, 49.6, and 118.9 per 100,000 overall habitants, males, and females, respectively. The most common sites among men were stomach (ASR 26.0, 52.4%), colorectal (ASR 5.11, 10.15%), and prostate (ASR 2.7, 5.4%). The most common sites in women were cervix (ASR 34.2, 36.7%), breast (ASR 11.2, 12.3%), and stomach (ASR 10.8, 11.7%). CONCLUSION The Copán-PBCR represents a successful model to develop cancer monitoring in rural LMICs. Innovations included the use of the REDCap platform and leverage of Health Ministry resources. This provides the first PBCR data for Honduras and the Central America Four and confirms that infection-driven cancers, such as gastric and cervical, should be priority targets for cancer control initiatives.

Increase in the incidence of differentiated thyroid carcinoma in children, adolescents, and young adults (AYA): A population-based study.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 9523-9523
Author(s):  
Lucas B. Vergamini ◽  
A. Lindsay Frazier ◽  
Fernanda L. Abrantes ◽  
Karina Braga Ribeiro ◽  
Carlos Rodriguez-Galindo
Keyword(s):  
Thyroid Cancer ◽  
Thyroid Carcinoma ◽  
Cancer Registries ◽  
International Classification Of Diseases ◽  
The United States ◽  
Differentiated Thyroid Carcinoma ◽  
Population Based ◽  
Incidence Rates ◽  
Primary Tumors ◽  
Increasing Trends

9523 Background: Studies have shown an increase in thyroid cancer incidence among adults since the 1990s. However, few studies have evaluated this occurrence among children and AYA. Increases resulting from enhanced detection are most likely to involve small tumors. The objective of this study is to investigate trends in incidence of differentiated thyroid carcinomas in children and AYA by size and sex. Methods: This is an ecological time-trend study. Cases of differentiated thyroid cancer (1984-2008) in patients younger than 30 years old were selected from SEER 9 cancer registries using International Classification of Diseases for Oncology 3rd edition (ICD-O-3) codes for papillary and follicular cancers (codes 8050/3, 8052/3, 8130/3, 8260/3, 8290/3, 8330-8332/3, 8335/3, 8340-8344/3, 8450/3 and 8452/3). Patients who had multiple primary tumors were excluded from the study. SEER*Stat software was used to calculate age-standardized rates (estimated per 1,000,000 persons; World Standard Population) and annual percentage changes (APC) were calculated using Joinpoint model. Results: Rates ranged from 2.77 (1990) to 7.45 (2002) for males and from 17.19 (1987) to 41.3 (2008) for females. Overall, a significant increasing trend in incidence was observed for females (APC=3.20, 95%CI 2.80, 3.60). When a stratified analysis based on tumor size was performed, significant increasing trends were noted for the following categories: 0.5-0.9 cm (Males: APC=3.50, 95%CI 1.50, 5.40; Females: APC=7.30, 95%CI 5.90, 8.80), 1.0-1.9 cm (Males: APC=3.20, 95%CI 1.00, 5.40; Females: APC=2.90, 95%CI 2.20, 3.70), and ≥ 2cm (Males: APC=1.30, 95%CI 0.30, 2.40; Females: APC=2.50, 95%CI 1.70, 3.20). However, no statistically significant trends were noted for tumors <0.5 cm (Males: APC=2.50, 95%CI -0.30, 5.40; Females: APC=2.0, 95%CI -6.90, 11.80). Conclusions: Incidence rates for differentiated thyroid carcinoma are also increasing among children and AYA in the United States. The absence of increasing trends for small tumors (< 0.5cm) rules out diagnostic scrutiny as the only explanation for the observed results. Environmental, dietary and genetic factors should be investigated.

scholarly journals EPID-12. TEMPORAL AND GLOBAL GEOGRAPHIC VARIATION IN THE INCIDENCE OF PEDIATRIC CNS TUMORS, 1998–2012

2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii321-iii321
Author(s):  
Karina Ribeiro ◽  
Sidnei Epelman
Keyword(s):  
Geographic Variation ◽  
Incidence Rates ◽  
Histological Subtype ◽  
Embryonal Tumors ◽  
Pooled Data ◽  
Males And Females ◽  
Rate Ratios ◽  
Increasing Trends ◽  
Central South ◽  
Cns Malignancies

Abstract AIMS To describe the temporal and geographic variation in the incidence of pediatric CNS malignancies worldwide, presenting analyses by sex, period, region, and histological subtype between 1998 and 2012. METHODS Data were extracted from volumes IX to XI of the Cancer Incidence in 5 Continents, covering the periods 1998–2002 (1), 2003–2007 (2), and 2008–2012 (3). We pooled data from 44 countries, classifying them into 6 regions (Africa (AF), Asia (AS), Oceania (O), Europe (E), Central/South America (CSA), North America (NA)). Age-standardized incidence rates (ASIR per million, 0–19 years) were calculated and temporal variation was evaluated using incidence rate ratios (IRR) (95% CI). RESULTS The highest incidence (Period 3) was observed in NA (34.0 and 30.2 for males and females, respectively). Astrocytic tumors were predominant in all regions, with percentages ranging between 24.5% (E, females) and 45.6% (NA, females). Increasing trends (Period 3 x 1) were observed in AS (IRR=1.15, 95% CI 1.06–1.25), CSA (IRR=1.25, 95% CI 1.01–1.55), and NA (IRR=1.05, 95% CI 1.03–1.07), for males and in AS (IRR=1.15, 95% CI 1.05–1.26) and NA (IRR=1.08, 95% CI 1.06–1.11) for females. Geographic discrepancies in time-trends were observed for astrocytomas, ependymomas, medulloblastomas, other embryonal tumors, and other specified tumors. Reductions in the incidence of unspecified tumors from period 1 to 3 were noted in E, AS, and NA, ranging from -20% (E, females) to -66% (AS, females). CONCLUSIONS Heterogeneous trends and improvement in the registration of histological types were noted. Geographic variation can help to raise hypotheses to investigate etiologic factors.

scholarly journals Quantitative electroencephalography as a tool for objective neurophysiological seizure diagnosis: A retrospective study

2020 ◽  
Vol 0 ◽  
pp. 1-6
Author(s):  
Rajesh Kumar ◽  
Tribhuwan Kumar ◽  
Kamlesh Jha ◽  
Yogesh Kumar
Keyword(s):  
Energy Level ◽  
Matched Control ◽  
Age Groups ◽  
Quantitative Electroencephalography ◽  
Beta Band ◽  
Significant Difference ◽  
Males And Females ◽  
The Mean ◽  
The Difference ◽  
Electrical Activities

Objectives: Seizure is the fourth most common neurological disorder in the world; it affects all age groups with equal possibility of occurrence in both males and females. Many antiepileptic drugs are available today, but its diagnosis is challenging. The present study attempted to see if seizure activities could be predicted by analyzing the pre-seizure electrical activities. The prediction may help in taking preventive measures appropriately beforehand in the individuals with seizure proneness. Material and Methods: We selected 11 generalized seizure patients and 19 control patients out of total 115 patients referred for electro-diagnostics for various reasons. EEG of the subjects recorded, segmented as per protocol, and analyzed using MATLAB and EEGLAB tools. Results: The mean energy level in alpha and beta band of the study subject was significantly lower (P = 0.04 and 0.004, respectively) as compared to the age matched control subjects. Theta and delta bands did not show any significant difference between the groups. The difference between the pre- and post-electrical seizure energy and entropy was statistically insignificant. Conclusion: The study shows that the energy level remains low in the seizure patients in the alpha and beta bands. This further goes down when electrophysiological seizure activities starts. The randomness or entropy does not alter significantly among the seizure subjects in comparison to non-seizure subjects.

Sex Differences in Adults on a Test of Logical Reasoning

1956 ◽  
Vol 2 (3) ◽  
pp. 227-230
Author(s):  
Antonia Bell Morgan
Keyword(s):  
Sex Differences ◽  
Logical Reasoning ◽  
Formal Logic ◽  
Government Employment ◽  
Significant Difference ◽  
Males And Females ◽  
The Mean

The Morgan Test of Logical Reasoning, which is entirely verbal in form, was given to 133 males and 35 females. All Ss were in their 20s and applicants for government employment. All had the BA or BS degree but no other, and none had had any training in formal logic. No significant difference was found between the mean scores of males and females on this test, nor between the distribution and variation of scores.

Risk-Taking Patterns of Male and Female Entrepreneurs in Roodepoort

2014 ◽  
Vol 13 (4) ◽  
pp. 452-478 ◽  
Author(s):  
Ajay K. Garg ◽  
A. Duvenhage
Keyword(s):  
Risk Taking ◽  
Business Performance ◽  
Health And Safety ◽  
Primary Data ◽  
Female Entrepreneurs ◽  
Male And Female ◽  
Significant Difference ◽  
Males And Females ◽  
The Mean ◽  
Performance Perceptions

This study analyses the risk-taking propensity of male and female entrepreneurs. Primary data were collected from a sample of 400 randomly selected from among the small and medium scale entrepreneurs in Roodepoort and two structured questionnaires were used. The results showed the existence of differences among male and female entrepreneurs’ risk-taking perceptions. However, no significant differences in the mean scores between males and females in the financial and social domains of risk taking perception were found. The results further indicate that there is a significant difference in the means of the entrepreneurs with regard to their overall risk-taking perception in the ethical domain of risk-taking perception, health and safety risk-taking perception, recreational risk-taking perception as well as their business performance perceptions. The study also suggests that there is no correlation between business performance and risk-taking in entrepreneurs. The study highlights that there is no evidence to suggest that risk-taking in different genders plays a role as an indicator in business performance.

scholarly journals Growth-Related Differences in Maximum Laterotrusion and Retrusion between Children and Adults

2009 ◽  
Vol 79 (2) ◽  
pp. 265-270 ◽  
Author(s):  
Claudia A. Reicheneder ◽  
Peter Proff ◽  
Uwe Baumert ◽  
Tomas Gedrange
Keyword(s):  
Temporomandibular Joint ◽  
Null Hypothesis ◽  
Population Based ◽  
Adult Group ◽  
Population Based Study ◽  
Significant Difference ◽  
Left And Right ◽  
The Mean ◽  
The Right

Abstract Objective: To test the null hypothesis that there are no differences between children and adults in maximum laterotrusion and maximum retrusion on the right and left sides. Materials and Methods: This population-based study included 81 randomly selected children between the ages of 6 and 10 years and 67 adults. Kinematic variables were measured with the ultrasonic JMA-System for registration. Results: The mean maximum laterotrusion of the children's group (10.6 ± 1.5 mm on the left, 11.0 ± 1.7 mm on the right) was significantly smaller than that of the adult group (11.7 ± 2.0 mm on the left, 12.2 ± 1.7 mm on the right). The maximum laterotrusion of the children's group corresponded to about 90% on the left and right sides of that of the adult group. The mean maximum retrusion of the children's group was significantly bigger than that of the adult group. There, the adult values corresponded to 66.7% on the left and 50% on the right side of the children's values. No significant difference in maximum laterotrusion and retrusion was noted on the right and left sides, and no significant differences according to gender specificities were observed in either group. Conclusions: The hypothesis is rejected. In development of the temporomandibular joint, maximum laterotrusion on the right and left sides increases significantly with age, and maximum retrusion decreases significantly with age.

scholarly journals Influence of sex and age on sonographic infant hip indices

2014 ◽  
Vol 2 (4) ◽  
Author(s):  
Kakale SB ◽  
Tabari AM ◽  
Isyaku K ◽  
Yunusa A
Keyword(s):  
Imaging Modality ◽  
Alpha Angle ◽  
Late Presentation ◽  
Radiology Department ◽  
Age Group ◽  
Hip Joints ◽  
Non Invasive ◽  
Significant Difference ◽  
Males And Females ◽  
The Mean

Ultrasound is a non-invasive, cheap and readily available imaging modality for studying the infant hip. Early detection of developmental hip subluxation, acetabular dysplasia and the prevention of late presentation of a developmentally dislocated hip with consequent secondary premature degenerative arthritis are goals that all practitioners should strive for. Provision of axial indices of alpha and beta angles of the infant hip joint in Kano, Nigeria using ultrasonography to establish a normogram as reference values for further studies is the objective of this study. This descriptive prospective study was conducted at the Radiology Department of Aminu Kano Teaching Hospital, Kano state, Nigeria. Successive four hundred appropriately consented infants were recruited for this study. The axial angle relationships of both hip joints were measured using 7.5 MHz linear transducer of Mindray DP-8800 Digital plus ultrasound machine. The mean alpha and beta angles for both hips in females were 56.590 and 49.580 respectively while those for males were 56.730 and 50.530 respectively. Minimum and maximum alpha angle for both hips ranged from 380 to 780 while the beta angles ranged 290 to 660 respectively. The age group 1-3 months has the highest frequency of respondents (251) while age group 10 - 12 months has the lowest (22). There was no statistically significant difference in the alpha and beta angles between males and females hips and age of the infants did not affect the hip indices. The study showed no statistical significant difference in the measured alpha and beta angles between males and females. Age of measurement in infants did not affect the hip indices.

scholarly journals The Impact of COVID-19 Infection on the Quality of Life of Health Care Workers

2021 ◽  
Author(s):  
Sadeel Shanshal ◽  
Harith Kh. Al-Qazaz
Keyword(s):  
Quality Of Life ◽  
Sleep Quality ◽  
Psychological Health ◽  
World Health ◽  
World Health Organization Quality ◽  
Significant Difference ◽  
Males And Females ◽  
The Mean ◽  
The Impact

Abstract Background: COVID-19 pandemic has negatively affected the entire world and one of its impacts was the increased level of stress and anxiety, especially among healthcare workers. Therefore, this study aims at evaluating the quality of life (QoL) and sleep quality of healthcare professionals in Iraq.Methods: This study assessed the QoL and sleep quality by using World Health Organization Quality of Life Instruments (WHOQOL-BREF) and the Insomnia Severity Index (ISI) respectively. The questionnaires were administered through an online cross-sectional survey targeted at workers in medical fields in Iraq from 1st to 20th of August 2021. Results: Three hundred medical health workers participated, and females constituted 75.3%. The two questionnaires had very good internal consistency. The highest scoring domain was the social relationships, followed by physical health. Significant difference was found in the mean scores of psychological health domain between males and females, with higher scores observed in males. The mean of the total ISI score was 11.58 ± 6.88 with a range between 0 and 27. Severe insomnia was observed in only 9.7% of the participants. A significant negative correlation (r = -0.118) was found between age and ISI scores of the participants. Significant differences were found between males and females with higher ISI mean score observed among males. Conclusion: The quality of life and sleep pattern can be impacted by COVID-19 infection with the psychological aspect of QoL being the most affected and some degrees of insomnia being observed in many participants.

scholarly journals DOP72 Perianal Crohn’s Disease in the biologic era: A population-based cohort study

2021 ◽  
Vol 15 (Supplement_1) ◽  
pp. S105-S107
Author(s):  
P Jenkinson ◽  
N Plevris ◽  
M Lyons ◽  
S Siakavellas ◽  
I Arnott ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Cumulative Incidence ◽  
Population Based ◽  
Incidence Rates ◽  
Percentage Change ◽  
Prescription Data ◽  
Annual Percentage Change ◽  
Kaplan Meier ◽  
Significant Difference

Abstract Background Peri-anal Crohn’s disease (pCD) significantly affects quality of life in patients with CD. The natural history of pCD in the era of biologic therapy is poorly understood. Perianal surgery includes examination under anaesthesia (EUA), drainage of peri-anal sepsis, seton instertion and fistula manipulation. EUA forms part of the standard of care at diagnosis of pCD and therefore can be used as a proxy for incidence of pCD. Methods CD patients were identified from the Lothian IBD registry, a physician validated registry of all IBD cases within Lothian which has been shown to be 94.3% complete. Prospectively collected coding data was used to identify peri-anal surgery, which was validated by review of the electronic health record. Biologic prescription data was extracted from the Lothian biologics database; a physician validated, prospectively collected registry. Time trend analysis was performed for the period 2000 to 2017 by 1) calculating annual incidence rates of peri-anal interventions for all patients with CD and estimating annual percentage change and 2) by calculating cumulative incidence of pCD and biologic prescription in newly diagnosed CD and 3) stratifying by era of diagnosis (Cohort 1: 2000–2008 and Cohort 2: 2009–2017. Results 2937 patients with CD were identified in the study period, with 1108 operations for pCD performed on 381 patients. Rates of surgery fell from 5.1 to 2.0 operations per 100 CD patients per year between 2000 and 2017 (p&lt;0.001) giving an annual percentage change of -3.4% (-4.9% to -1.9% 95% CI) (fig 1). 1753 new diagnoses of CD were made of whom 247 developed pCD. 5 year risk of pCD was 12.8% (9.5–16.6%) with no significant difference identified between cohort 1 (11.5%) and cohort 2 (13.8%) (p=0.116) (fig 2). The 5 year incidence of biologic prescription for patients with pCD increased from 11.2% in cohort 1 to 58.1% in cohort 2 (p&lt;0.001) (fig 3). Figure 1: Number of peri-anal interventions per 100 CD patients per year (multiple procedures per patient included). Figure 2: Kaplan Meier curves showing cumulative incidence of pCD stratified by era of diagnosis. Figure 3: Kaplan Meier curves showing cumulative incidence of biologic prescription in patients with CD stratified by era of diagnosis and presence of pCD. Conclusion The incidence of pCD remains unchanged over time. Although we cannot ascribe causality, the overall decrease in surgery for pCD has been paralleled by a marked increase in the use of biologic medication.

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