scholarly journals Recent Advances in Injectable Hydrogels for Biomedical Applications

2019 ◽  
Vol 2 (1) ◽  
pp. 1 ◽  
Author(s):  
Eko Adi Prasetyanto
Keyword(s):  
Tissue Engineering ◽  
Biomedical Applications ◽  
State Of The Art ◽  
Research Progress ◽  
Hybrid Hydrogel ◽  
Injectable Hydrogels ◽  
Injectable Hydrogel ◽  
Different Types ◽  
And Cartilage ◽  
Recent Research Progress

Injectable hydrogels, a class of hydrogel, have received a lot of attention in biomedical applications due to its versatility. It is reported that injectable hydrogel can be applied in various biomedical procedures for example as submucosal fluid cushion, periodontal implant, and cartilage and bone tissue engineering. In addition to its easy delivery (implantation), this class of hydrogel can be tailored to match specific applications. The customization of this hydrogel can be easily executed by changing polymeric backbone of hydrogel, choosing different types of crosslinking or by adding nanoparticles to form hybrid hydrogel systems. Physical properties, compatibility and biodegradability of the resulted materials are important factors for designing injectable hydrogels. In this Recent Research Progress, we highlight the state-of-the-art injectable hydrogels and note the general requirements of an ideal injectable hydrogel for biomedical applications.

Bioapplications of hyperbranched polymers

2015 ◽  
Vol 44 (12) ◽  
pp. 4023-4071 ◽  
Author(s):  
Dali Wang ◽  
Tianyu Zhao ◽  
Xinyuan Zhu ◽  
Deyue Yan ◽  
Wenxin Wang
Keyword(s):  
Biomedical Applications ◽  
Hyperbranched Polymers ◽  
Research Progress ◽  
Recent Research Progress

The recent research progress in biological and biomedical applications of hyperbranched polymers has been summarized in this review.

scholarly journals Gold Nanomaterials and Bone/Cartilage Tissue Engineering: Biomedical Applications and Molecular Mechanisms

2021 ◽  
Vol 9 ◽  
Author(s):  
Yifeng Shi ◽  
Xuyao Han ◽  
Shuang Pan ◽  
Yuhao Wu ◽  
Yuhan Jiang ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Biomedical Applications ◽  
Rational Design ◽  
Molecular Mechanisms ◽  
Materials Science ◽  
Rapid Development ◽  
Cartilage Tissue Engineering ◽  
Cartilage Tissue ◽  
Gold Nanomaterials ◽  
And Cartilage

Recently, as our population increasingly ages with more pressure on bone and cartilage diseases, bone/cartilage tissue engineering (TE) have emerged as a potential alternative therapeutic technique accompanied by the rapid development of materials science and engineering. The key part to fulfill the goal of reconstructing impaired or damaged tissues lies in the rational design and synthesis of therapeutic agents in TE. Gold nanomaterials, especially gold nanoparticles (AuNPs), have shown the fascinating feasibility to treat a wide variety of diseases due to their excellent characteristics such as easy synthesis, controllable size, specific surface plasmon resonance and superior biocompatibility. Therefore, the comprehensive applications of gold nanomaterials in bone and cartilage TE have attracted enormous attention. This review will focus on the biomedical applications and molecular mechanism of gold nanomaterials in bone and cartilage TE. In addition, the types and cellular uptake process of gold nanomaterials are highlighted. Finally, the current challenges and future directions are indicated.

scholarly journals Research Progress on Conducting Polymer-Based Biomedical Applications

2019 ◽  
Vol 9 (6) ◽  
pp. 1070 ◽  
Author(s):  
Yohan Park ◽  
Jaehan Jung ◽  
Mincheol Chang
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Electrical Properties ◽  
Biomedical Engineering ◽  
Biomedical Applications ◽  
Full Range ◽  
Environmental Stability ◽  
Research Progress ◽  
Artificial Muscles ◽  
Main Function

Conducting polymers (CPs) have attracted significant attention in a variety of research fields, particularly in biomedical engineering, because of the ease in controlling their morphology, their high chemical and environmental stability, and their biocompatibility, as well as their unique optical and electrical properties. In particular, the electrical properties of CPs can be simply tuned over the full range from insulator to metal via a doping process, such as chemical, electrochemical, charge injection, and photo-doping. Over the past few decades, remarkable progress has been made in biomedical research including biosensors, tissue engineering, artificial muscles, and drug delivery, as CPs have been utilized as a key component in these fields. In this article, we review CPs from the perspective of biomedical engineering. Specifically, representative biomedical applications of CPs are briefly summarized: biosensors, tissue engineering, artificial muscles, and drug delivery. The motivation for use of and the main function of CPs in these fields above are discussed. Finally, we highlight the technical and scientific challenges regarding electrical conductivity, biodegradability, hydrophilicity, and the loading capacity of biomolecules that are faced by CPs for future work. This is followed by several strategies to overcome these drawbacks.

Fluoropolymers in biomedical applications: state-of-the-art and future perspectives

2021 ◽  
Author(s):  
Jia Lv ◽  
Yiyun Cheng
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Cell Culture ◽  
Gene Delivery ◽  
Bacterial Cell ◽  
Protein Delivery ◽  
Biomedical Applications ◽  
State Of The Art ◽  
Future Perspectives

Biomedical applications of fluoropolymers in gene delivery, protein delivery, drug delivery, 19F MRI, PDT, anti-fouling, anti-bacterial, cell culture, and tissue engineering.

scholarly journals Simultaneous differentiation of articular and transient cartilage: WNT-BMP interplay and its therapeutic implication

2020 ◽  
Vol 64 (1-2-3) ◽  
pp. 203-211
Author(s):  
Tathagata Biswas ◽  
Akrit P. Jaswal ◽  
Upendra S. Yadav ◽  
Amitabha Bandyopadhyay
Keyword(s):  
Tissue Engineering ◽  
Developmental Biology ◽  
Endochondral Ossification ◽  
Recent Literature ◽  
New Paradigm ◽  
Treatment Of Osteoporosis ◽  
Chondrocyte Maturation ◽  
Different Types ◽  
Insight Into ◽  
And Cartilage

Limb skeleton forms through the process of endochondral ossification. This process of osteogenesis proceeds through an intermediate cartilage template and involves several stages of chondrocyte maturation and eventual bone formation. During the process of endochondral ossification, interplay between BMP and WNT signaling regulate simultaneous differentiation of articular and transient cartilage. In this review, we focus on the recent literature which explores the simultaneous differentiation of these two different types of cartilage. We discuss a new paradigm of developmental biology-inspired tissue engineering of bone and cartilage grafts and provide novel insight into treatment of osteoporosis.

scholarly journals Circularly Polarized Photodetectors Based on Chiral Materials: A Review

2021 ◽  
Vol 9 ◽  
Author(s):  
Can Zhang ◽  
Xiaohong Wang ◽  
Longzhen Qiu
Keyword(s):  
Optical Communication ◽  
Polarized Light ◽  
Research Progress ◽  
Circularly Polarized Light ◽  
Circularly Polarized ◽  
Different Types ◽  
Quarter Wave ◽  
Chiral Materials ◽  
Optical Calculation ◽  
Recent Research Progress

Circularly polarized light (CPL) plays an important role in many photonic techniques, including tomographic scanning based on circular polarization ellipsometry, optical communication and information of spin, and quantum-based optical calculation and information processing. To fully exploit the functions of CPL in these fields, integrated photoelectric sensors capable of detecting CPL are essential. Photodetectors based on chiral materials can directly detect CPL due to their intrinsic optical activity, without the need to be coupled with polarizers and quarter-wave plates as in conventional photodetectors. This review summarizes the recent research progress in CPL photodetectors based on chiral materials. We first briefly introduce the CPL photodetectors based on different types of chiral materials and their working principles. Finally, current challenges and future opportunities in the development of CPL photodetectors are prospected.

Automated Formal Methods for Security Protocol Engineering

2011 ◽  
pp. 138-166
Author(s):  
Alfredo Pironti ◽  
Davide Pozza ◽  
Riccardo Sisto
Keyword(s):  
Formal Methods ◽  
State Of The Art ◽  
Security Protocols ◽  
Security Protocol ◽  
Research Progress ◽  
Engineering Practice ◽  
Key Factor ◽  
Level Model ◽  
High Level ◽  
Recent Research Progress

Designing and implementing security protocols are known to be error-prone tasks. Recent research progress in the field of formal methods applied to security protocols has enabled the use of these techniques in practice. The objective of this chapter is to give a circumstantial account of the state-of-the-art reached in this field, showing how formal methods can help in improving quality. Since automation is a key factor for the acceptability of these techniques in the engineering practice, the chapter focuses on automated techniques and illustrates in particular how high-level protocol models in the Dolev-Yao style can be automatically analyzed and how it is possible to automatically enforce formal correspondence between an abstract high-level model and an implementation.

A Review on Cellulose-based Materials for Biomedicine

2022 ◽  
Author(s):  
Hani Nasser Abdelhamid ◽  
Aji P. Mathew
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Wound Healing ◽  
Biomedical Applications ◽  
Chemical Structure ◽  
Antibacterial Agents ◽  
State Of The Art ◽  
Market Demand ◽  
Mechanical And Physical Properties ◽  
Research Findings

There are various biomaterials in nature, but none fulfills all the requirements. Cellulose, eco-friendly material-based biopolymers, have been advanced biomedicine to satisfy most market demand and circumvent many ecological concerns. This review aims to present an overview of the state of the art in cellulose's knowledge and technical biomedical applications. It included an extensive bibliography of recent research findings for fundamental and applied investigations. The chemical structure of cellulose allows modifications and simple conjugation with several materials, including nanoparticles, without tedious efforts. Cellulose-based materials were used for biomedicine applications such as antibacterial agents, antifouling, wound healing, drug delivery, tissue engineering, and bone regeneration. They advanced the applications to be cheap, biocompatible, biodegradable, easy for shaping and processing into different forms, with suitable chemical, mechanical and physical properties.

An injectable hydrogel formed by in situ cross-linking of glycol chitosan and multi-benzaldehyde functionalized PEG analogues for cartilage tissue engineering

2015 ◽  
Vol 3 (7) ◽  
pp. 1268-1280 ◽  
Author(s):  
Luping Cao ◽  
Bin Cao ◽  
Chengjiao Lu ◽  
Guowei Wang ◽  
Lin Yu ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cartilage Tissue Engineering ◽  
Cartilage Tissue ◽  
Cross Linking ◽  
Glycol Chitosan ◽  
Injectable Hydrogels ◽  
Injectable Hydrogel ◽  
Cross Linker ◽  
Aldehyde Groups

A novel PEG analogue, poly(EO-co-Gly)-CHO, that possesses multiple aldehyde groups is designed and synthesized, and then is used as a cross-linker to react with glycol chitosan to create injectable hydrogels.

scholarly journals Cellular Signaling Pathways Activated by Functional Graphene Nanomaterials

2018 ◽  
Vol 19 (11) ◽  
pp. 3365 ◽  
Author(s):  
Anna Piperno ◽  
Angela Scala ◽  
Antonino Mazzaglia ◽  
Giulia Neri ◽  
Rosamaria Pennisi ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Signaling Pathways ◽  
Biomedical Applications ◽  
State Of The Art ◽  
Cellular Signaling ◽  
Molecular Device ◽  
Transmembrane Receptors ◽  
Signal Transducers ◽  
Extracellular Signals ◽  
Target Sites

The paper reviews the network of cellular signaling pathways activated by Functional Graphene Nanomaterials (FGN) designed as a platform for multi-targeted therapy or scaffold in tissue engineering. Cells communicate with each other through a molecular device called signalosome. It is a transient co-cluster of signal transducers and transmembrane receptors activated following the binding of transmembrane receptors to extracellular signals. Signalosomes are thus efficient and sensitive signal-responding devices that amplify incoming signals and convert them into robust responses that can be relayed from the plasma membrane to the nucleus or other target sites within the cell. The review describes the state-of-the-art biomedical applications of FGN focusing the attention on the cell/FGN interactions and signalosome activation.

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