Fluoropolymers in biomedical applications: state-of-the-art and future perspectives

2021 ◽  
Author(s):  
Jia Lv ◽  
Yiyun Cheng
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Cell Culture ◽  
Gene Delivery ◽  
Bacterial Cell ◽  
Protein Delivery ◽  
Biomedical Applications ◽  
State Of The Art ◽  
Future Perspectives

Biomedical applications of fluoropolymers in gene delivery, protein delivery, drug delivery, 19F MRI, PDT, anti-fouling, anti-bacterial, cell culture, and tissue engineering.

Nanofibrous Substrate For Tissue Engineering Applications—A Review

2021 ◽  
Vol 8 (6) ◽  
pp. 13-21
Author(s):  
Odia Osemwegie ◽  
Lihua Lou ◽  
Ernest Smith ◽  
Seshadri Ramkumar
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Cell Culture ◽  
Tissue Regeneration ◽  
Biomedical Applications ◽  
High Volume ◽  
Clinical Applications ◽  
Critical Factors ◽  
Engineering Applications

Nanofiber substrates have been used for various biomedical applications, including tissue regeneration, drug delivery, and in-vitro cell culture. However, despite the high volume of studies in this field, current clinical applications remain minimal. Innovations for their applications continuously generate exciting prospects. In this review, we discuss some of these novel innovations and identify critical factors to consider before their adoption for biomedical applications.

Advances in drug delivery, gene delivery and therapeutic agents based on dendritic materials

2019 ◽  
Vol 11 (14) ◽  
pp. 1791-1810 ◽  
Author(s):  
Mario Contin ◽  
Cybele Garcia ◽  
Cecilia Dobrecky ◽  
Silvia Lucangioli ◽  
Norma D’Accorso
Keyword(s):  
Drug Delivery ◽  
Gene Delivery ◽  
Biomedical Applications ◽  
State Of The Art ◽  
Synthetic Polymers ◽  
Therapeutic Agents ◽  
Therapeutic Strategies ◽  
Common Point ◽  
Three Dimensions ◽  
Dendrimer Conjugates

Dendrimers are synthetic polymers that grow in three dimensions into well-defined structures. Their morphological appearance resembles a number of trees connected by a common point. Dendritic nanoparticles have been studied for a large number of pharmaceutical and biomedical applications including gene and drug delivery, clinical diagnosis and MRI. Despite the application of dendrimers, research is still in its childhood in comparison with liposomes and other nanomaterials. They are now playing a key role in several therapeutic strategies, with dendrimer-based products in clinical trials. The aim of this review is to describe the state-of-the-art of biomedical applications of dendrimers – and dendrimer conjugates – such as drug and gene delivery and antiviral activity.

scholarly journals Functional Glycopolypeptides: Synthesis and Biomedical Applications

2020 ◽  
Vol 2020 ◽  
pp. 1-16
Author(s):  
Zhao Wang ◽  
Xiaojuan Zhang ◽  
Qing Lin ◽  
Jingjing Sun ◽  
Santanu Bhattachaya ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cell Culture ◽  
Cell Adhesion ◽  
Gene Delivery ◽  
Green Chemistry ◽  
Biomedical Applications ◽  
Biomolecular Recognition ◽  
Biological Applications ◽  
Future Outlook

Employing natural-based renewable sugar and saccharide resources to construct functional biopolymer mimics is a promising research frontier for green chemistry and sustainable biotechnology. As the mimics/analogues of natural glycoproteins, synthetic glycopolypeptides attracted great attention in the field of biomaterials and nanobiotechnology. This review describes the synthetic strategies and methods of glycopolypeptides and their analogues, the functional self-assemblies of the synthesized glycopolypeptides, and their biological applications such as biomolecular recognition, drug/gene delivery, and cell adhesion and targeting, as well as cell culture and tissue engineering. Future outlook of the synthetic glycopolypeptides was also discussed.

Engineering β-sheet peptide assemblies for biomedical applications

2016 ◽  
Vol 4 (3) ◽  
pp. 365-374 ◽  
Author(s):  
Zhiqiang Yu ◽  
Zheng Cai ◽  
Qiling Chen ◽  
Menghua Liu ◽  
Ling Ye ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Cell Culture ◽  
Biomedical Applications ◽  
Β Sheet

Hydrogels have been widely studied in various biomedical applications, such as tissue engineering, cell culture, immunotherapy and vaccines, and drug delivery.

N-succinyl chitosan preparation, characterization, properties and biomedical applications: a state of the art review

2015 ◽  
Vol 31 (6) ◽  
Author(s):  
Shahid Bashir ◽  
Yin Yin Teo ◽  
S. Ramesh ◽  
K. Ramesh ◽  
Amir Azam Khan
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Protein Delivery ◽  
State Of The Art ◽  
Transfection Efficiency ◽  
Aqueous Solubility ◽  
Biological Properties ◽  
Wound Dressings ◽  
Comprehensive Overview ◽  
Biomedical Field

AbstractN-succinyl chitosan (NSC) remains a promising chitosan derivative to develop targeted drug delivery, wound dressings, and tissue engineering systems. All these systems are important in life sciences. NSC is an amphiprotic derivative obtained from the N-acylation of chitosan. NSC exhibits extraordinary biocompatibility, significantly increased aqueous solubility in acidic and basic media without affecting the biological properties, appreciable transfection efficiency, and the ability to stimulate osteogenesis. NSC shows enhanced bioavailability, which highlights its potential applications in the biomedical field. This review briefly introduces chitosan, including its limitations as a biomaterial, and modifications of chitosan with a particular focus on acylation, along with a comprehensive overview of the synthesis, characterization, properties, biodistribution, and toxicological/biopharmaceutical profile of NSC. Furthermore, it extensively surveys current state-of-the-art NSC-based formulations for drug delivery with special emphasis on protein delivery, anti-cancer activity in the colon, as well as nasal and ophthalmic targeted gene/drug delivery. Moreover, it discusses NSC-based biomaterial applications in articular, adipose, and bone tissue engineering. In addition, it describes recent contributions of NSC-based hydrogels in wound dressings along with a brief account of drug delivery in combination with tissue engineering. Finally, it presents potential current challenges and future perspectives of NSC-based formulations in the biomedical field.

A Review on Cellulose-based Materials for Biomedicine

2022 ◽  
Author(s):  
Hani Nasser Abdelhamid ◽  
Aji P. Mathew
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Wound Healing ◽  
Biomedical Applications ◽  
Chemical Structure ◽  
Antibacterial Agents ◽  
State Of The Art ◽  
Market Demand ◽  
Mechanical And Physical Properties ◽  
Research Findings

There are various biomaterials in nature, but none fulfills all the requirements. Cellulose, eco-friendly material-based biopolymers, have been advanced biomedicine to satisfy most market demand and circumvent many ecological concerns. This review aims to present an overview of the state of the art in cellulose's knowledge and technical biomedical applications. It included an extensive bibliography of recent research findings for fundamental and applied investigations. The chemical structure of cellulose allows modifications and simple conjugation with several materials, including nanoparticles, without tedious efforts. Cellulose-based materials were used for biomedicine applications such as antibacterial agents, antifouling, wound healing, drug delivery, tissue engineering, and bone regeneration. They advanced the applications to be cheap, biocompatible, biodegradable, easy for shaping and processing into different forms, with suitable chemical, mechanical and physical properties.

scholarly journals ADVANCES OF NON-IRON METAL NANOPARTICLES IN BIOMEDICINE

2021 ◽  
Vol 24 ◽  
pp. 41-61
Author(s):  
Anroop B. Nair ◽  
Mohamed A. Morsy ◽  
Pottathil Shinu ◽  
Sabna Kotta ◽  
Mithra Chandrasekaran ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Antimicrobial Activity ◽  
Gene Delivery ◽  
Anticancer Activity ◽  
Metal Nanoparticles ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Metallic Elements ◽  
Iron Metal

Metal nanoparticles (MNPs) comprise of nanoparticles originating from metallic elements with additional properties inherent to metal ions. MNPs found applications in various field such as electronics, optics, mechanics, physics etc. There are many reviews on iron MNPs for biomedical application. Hence, in this review, we focus on non-iron MNPs and their vivid biomedical applications. Here, we review the applications of non-iron MNPs in biomedicine such as drug delivery, gene delivery, anticancer activity, antimicrobial activity, tissue engineering, bioimaging, and photodynamic, and photothermal therapies.

Breath figures in tissue engineering and drug delivery: State-of-the-art and future perspectives

2018 ◽  
Vol 66 ◽  
pp. 44-66 ◽  
Author(s):  
Maria Teresa Calejo ◽  
Tanja Ilmarinen ◽  
Heli Skottman ◽  
Minna Kellomäki
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
State Of The Art ◽  
Future Perspectives ◽  
Breath Figures

Graphene and Graphene-Based Materials in Biomedical Applications

2019 ◽  
Vol 26 (38) ◽  
pp. 6834-6850 ◽  
Author(s):  
Mohammad Omaish Ansari ◽  
Kalamegam Gauthaman ◽  
Abdurahman Essa ◽  
Sidi A. Bencherif ◽  
Adnan Memic
Keyword(s):  
Tissue Engineering ◽  
Thermal Properties ◽  
Gene Delivery ◽  
Regenerative Medicine ◽  
Biomedical Research ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Two Dimensional ◽  
Drug And Gene Delivery ◽  
Biomedical Fields

: Nanobiotechnology has huge potential in the field of regenerative medicine. One of the main drivers has been the development of novel nanomaterials. One developing class of materials is graphene and its derivatives recognized for their novel properties present on the nanoscale. In particular, graphene and graphene-based nanomaterials have been shown to have excellent electrical, mechanical, optical and thermal properties. Due to these unique properties coupled with the ability to tune their biocompatibility, these nanomaterials have been propelled for various applications. Most recently, these two-dimensional nanomaterials have been widely recognized for their utility in biomedical research. In this review, a brief overview of the strategies to synthesize graphene and its derivatives are discussed. Next, the biocompatibility profile of these nanomaterials as a precursor to their biomedical application is reviewed. Finally, recent applications of graphene-based nanomaterials in various biomedical fields including tissue engineering, drug and gene delivery, biosensing and bioimaging as well as other biorelated studies are highlighted.

scholarly journals The effects of cononsolvents on the synthesis of responsive particles via polymerisation-induced thermal self-assembly

2021 ◽  
Author(s):  
Marissa Morales-Moctezuma ◽  
Sebastian G Spain
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Self Assembly ◽  
Biomedical Applications

Nanogels have emerged as innovative platforms for numerous biomedical applications including gene and drug delivery, biosensors, imaging, and tissue engineering. Polymerisation-induced thermal self-assembly (PITSA) has been shown to be suitable...

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