SILENT ATRIAL FIBRILLATION AS A RISK FACTOR FOR FALLS IN THE ELDERLY

Author(s):  
А.В. Турушева ◽  
Е.В. Фролова ◽  
Ю.М. Петросян ◽  
Р.Д. Думбадзе

Падения повышают риск травм, инвалидизации и смертности пожилых людей. Фибрилляция предсердий (ФП) является одним из факторов риска падений в пожилом возрасте, тем не менее, связь между «скрытой» ФП и падениями не исследована. В исследование были включены пациенты 60 лет и старше (n=131), находившиеся на лечении в Городском гериатрическом медикосоциальном центре. Диагностированная ранее ФП была выявлена у 13,7 % (n=18) участников исследования, «скрытая» ФП - у 11,5 % (n=15). Обе формы ФП были ассоциированы с четырехкратным увеличением частоты падений в пожилом возрасте: (95 % ДИ) 4,26 (1,18-15,40) для ранее выявленной ФП и 4,56 (1,25-16,66) для «скрытой» ФП. Скрининг ФП позволил выявить на 16,9 % (95 % ДИ 6,7-26,8 %; p<0,001) больше пациентов, находящихся в группе риска падений. Таким образом, «скрытая» ФП, как и ранее диагностированная, являются независимыми факторами риска падений. Проведение скрининга ФП позволяет выявлять большее число пожилых пациентов, находящихся в группе риска падений. Falls increase the risk of injury, disability, and death in the elderly. Atrial fibrillation (AF) is one of the risk factors for falls in old age, however, the relationship between «silent» AF and falls has not been investigated. The study included patients (n=131) from 60 years and older who admitted in the City geriatric medical and social center. Previously diagnosed AF was detected in 13,7 % (n=18) of the study participants, and «silent» AF was detected in 11,5 % (n=15). Both forms of AF were associated with a 4-fold increase in the incidence of falls in old age: (95 % CI) 4,26 (1,18-15,40) for previously detected AF and 4,56 (1,25-16,66) for «silent» AF. AF screening revealed 16,9 % (95 % CI 6,7-26,8 %; p<0,001) more patients at risk of falls. Thus, «silent» AF, as well as previously diagnosed, are independent risk factors for falls. Conducting AF screening allows to identify more elderly patients who are at risk of falls.

2019 ◽  
Vol 12 ◽  
pp. 117954411988493 ◽  
Author(s):  
Anneli Teder-Braschinsky ◽  
Aare Märtson ◽  
Marika Rosenthal ◽  
Pille Taba

Objectives: Deteriorating functionality and loss of mobility, resulting from Parkinson’s disease, may be worsened by osteoarthritis, which is the most common form of joint disease causing pain and functional impairment. We assessed the association between symptomatic hip or knee osteoarthritis, falls, and the ability to walk among patients with Parkinson’s disease compared to a control group. Methods: A total of 136 patients with Parkinson’s disease in Southern Estonia and 142 controls with an average age of 76.8 and 76.3 years, respectively, were enrolled in a retrospective case-control study. Information on falls and related fractures during the previous year was collected from the patients with Parkinson’s disease and controls. Covariates included gender, age, mobility, duration of Parkinson’s disease, and fractures. Results: Patients with Parkinson’s disease were at an increased risk of falls compared to the control group, and for the higher risk of fractures. Symptomatic knee or hip osteoarthritis was a significant independent predictor of falls in both patients with Parkinson’s disease and controls. The higher risk for fractures during the previous year was demonstrated in symptomatic osteoarthritis. Risk factors for falls included also female gender, use of sleep pills, and the inability to walk 500 m. Conclusions: Symptomatic hip and knee osteoarthritis are risk factors for falls and related fractures among the elderly population with and without Parkinson’s disease. The inability to walk 500 m could be used as a simple predictive factor for the increased risk of falls among elderly populations.


Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 1333-1333
Author(s):  
Mei S. Duh ◽  
Samir H. Mody ◽  
Patrick Lefebvre ◽  
Richard C. Woodman ◽  
Sharon Buteau ◽  
...  

Abstract Background: Anemia commonly occurs in the elderly (≥65), and has been associated with a number of adverse consequences. Thirty percent of the community-dwelling elderly fall annually and this risk increases to 50% by the age of 80. Serious injuries caused by a fall, such as fractures and head injuries, are sustained by about 10% of the elderly and often lead to functional disability, increased health care costs, and increased mortality. Identification of reversible risk factors is critical for the management of falls and related injuries. The purpose of the current study is to investigate whether anemia increases the risk of injurious falls (IF) in the elderly. Methods: Health claims data from over 30 health plans from 01/1999 through 04/2004 were used. Patients ≥65 years with ≥1 hemoglobin (Hb) measurement were selected. IF were defined as a fall claim followed by an injurious event claim within 30 days after the fall. Injurious events were defined as fractures of the hip, pelvis, femur, vertebrae, ribs, humerus, and lower limbs, Colle’s fracture, head injuries, or hematomas. An open-cohort design was employed to classify patients’ observation periods by: (1) by anemia status based on WHO criteria (&lt; 12 g/dL for women; &lt; 13 g/dL for men), and (2) by Hb level: &lt;10, 10-&lt;12, 12-&lt;13, and ≥13 g/dL. The incidence rates (IF events / person-years of observation) were compared by anemia status and Hb levels, respectively. Subset analyses based on IF of the hip (including pelvis and femur) and the head were further conducted. The association of IF with anemia and Hb levels, respectively, was analyzed using both univariate and multivariate (adjusted for age, gender, health plan, comorbidities, concomitant medications) approaches. Results: Among the 47,530 study subjects, a statistically significant linear trend of increasing risk of falls (i.e., IF and non-IF events) with decreasing Hb was observed (p&lt;.0001). The incidence of IF was 15.8, 14.0, 9.8, and 6.5 per 1,000 person-years for Hb levels of &lt;10, 10-&lt;12, 12-&lt;13, and ≥13 g/dL, respectively (trend: p&lt;.0001). Based on the univariate analysis, anemia increased the risk of IF by 1.66 times (95% CI: 1.41–1.95) compared to no anemia, and the effects of anemia on IF of the hip and head were more pronounced (rate ratio (RR)=2.25 [95% CI: 1.74–2.89] and 1.77 [95% CI: 1.22–2.55], respectively, (p&lt;.01 for both)). Multivariate analysis revealed that Hb levels were significantly associated with the risk of IF (RR = 1.57, 1.48, 1.17 for Hb levels of &lt;10, 10-&lt;12, 12-&lt;13 g/dL, respectively, compared to Hb≥ 13 g/dL), and the negative linear trend of the risk of IF by Hb levels remained statistically significant (p&lt;.0001). In the subset of hip and head IF, the association with anemia was even stronger (Hip: RR=3.37, 1.83, 1.36 for Hb levels of &lt;10, 10-&lt;12, 12-&lt;13 g/dL, respectively; Head: RR=1.65, 1.47, 1.18, respectively), with a statistically significant linear trend observed (Hip: p&lt;.0001; Head: p=0.07). Anemia (esp. Hb &lt; 10) had comparable risk to other well-known risk factors for falls such as Alzheimer’s disease, Parkinson’s disease, and osteoarthritis. Conclusion: Anemia was significantly and independently associated with an increasing risk for IF, especially IF to the hip and head, in elderly persons. Furthermore, the risk of IF increased as the anemia worsened. The impact of anemia correction on the risk of falls and IF needs to be evaluated.


2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
C V Madsen ◽  
B Leerhoey ◽  
L Joergensen ◽  
C S Meyhoff ◽  
A Sajadieh ◽  
...  

Abstract Introduction Post-operative atrial fibrillation (POAF) is currently considered a phenomenon rather than a definite diagnosis. Nevertheless, POAF is associated with an increased rate of complications, including stroke and mortality. The incidence of POAF in acute abdominal surgery has not been reported and prediction of patients at risk has not previously been attempted. Purpose We aim to report the incidence of POAF after acute abdominal surgery and provide a POAF prediction model based on pre-surgery risk-factors. Methods Designed as a prospective, single-centre, cohort study of unselected adult patients referred for acute, general, abdominal surgery. Consecutive patients (&gt;16 years) were included during a three month period. No exclusion criteria were applied. Follow-up was based on chart reviews, including medical history, vital signs, blood samples and electrocardiograms. Chart reviews were performed prior to surgery, at discharge, and three months after surgery. Atrial fibrillation was diagnosed either by specialists in Cardiology or Anaesthesiology on ECG or cardiac rhythm monitoring (≥30 seconds duration). Multiple logistic regression with backward stepwise selection was used for model development. Receiver operating characteristic curves (ROC) including area under the curve (AUC) was produced. The study was approved by the Regional Ethics committee (H-19033464) and comply with the principles of the Declaration of Helsinki of the World Medical Association. Results In total, 466 patients were included. Mean (±SD) age was 51.2 (20.5), 194 (41.6%) were female, and cardiovascular comorbidity was present in ≈10% of patients. Overall incidence of POAF was 5.8% (27/466) and no cases were observed in patients &lt;60 years. Incidence was 15.7% (27/172) for patients ≥60 years. Prolonged hospitalization and death were observed in 40.7% of patients with POAF vs 8.4% patients without POAF (p&lt;0.001). Significant age-adjusted risk-factors were previous atrial fibrillation odds ratio (OR) 6.84 [2.73; 17.18] (p&lt;0.001), known diabetes mellitus OR 3.49 [1.40; 8.69] (p=0.007), and chronic kidney disease OR 3.03 [1.20; 7.65] (p=0.019). A prediction model, based on age, previous atrial fibrillation, diabetes mellitus and chronic kidney disease was produced (Figure 1), and ROC analysis displayed AUC 88.26% (Figure 2). Conclusions A simple risk-stratification model as the one provided, can aid clinicians in identifying those patients at risk of developing POAF in relation to acute abdominal surgery. This is important, as patients developing POAF are more likely to experience complications, such as prolonged hospitalization and death. Closer monitoring of heart rhythm and vital signs should be considered in at-risk patients older than 60 years. Model validation is warranted. FUNDunding Acknowledgement Type of funding sources: None.


2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Ravika Ramlis

The incidence of falls in the elderly group may cause injury to the soft tissues and fractures of the thigh or wrist and even result in death. In addition, the State also can cause a variety of health problems including: pain, physical discomfort, the limitations of mobilization, and the slow healing process so that it will have an impact towards kondisilansia, where they will experience the problem of addiction to perform daily activities.Research methods the research design used was descriptive analytic. The study tried to gather information on factor-related risk factors for falls in the elderly include factor intrinsic, extrinsic, and circumstantial. The sample in this study is the whole elderly in BPPLU city of Bengkulu , namely an amount of 60 people. The method of sampling in this research are the total sampling.The results showed that there is a relationship between the intrinsic risk factors for falls in the elderly in Bengkulu City Year 2017 BPPLU. There is a relationship between extrinsic factors with risk of falls in the elderly in Bengkulu City Year 2017 BPPLU. Researchers suggest to the BPPLU can be a cornerstone of the implementation of the programme of activities, coaching, guidance and counseling in an attempt to increase knowledge about the factors factors that are associated with the risk of falls in the elderly.


Author(s):  
Karina Stella Aoki Ferreira ◽  
Anna Raquel Silveira Gomes

Introdução: A identificação dos fatores de risco ambientais de quedas é determinante para a prevenção deste evento em idosos da comunidade. Objetivo: Apresentar as principais diretrizes para a avaliação dos riscos ambientais de quedas em idosos da comunidade. Método: Revisão narrativa de literatura com pesquisa bibliográfica realizada por meio de busca nas bases de dados LILACS, MEDLINE, SciELO e PubMed no período de agosto a novembro de 2018. Resultados: As diretrizes sobre riscos de quedas em idosos da comunidade recomendam a realização de avaliação multifatorial, incluindo fatores de risco intrínsecos e extrínsecos, com destaque para os fatores domiciliares. Diversas abordagens e ferramentas têm sido utilizadas para a avaliação do risco de quedas em idosos da comunidade.  Entre os instrumentos validados para a avaliação de riscos ambientais residenciais, a maioria requer visita domiciliar pelo profissional de saúde para ser aplicado. Conclusão: Avaliação multifatorial é fundamental para identificar os principais fatores de risco para quedas em idosos da comunidade. A identificação de perigos no domicílio é um dos requisitos fundamentais para uma avaliação eficiente.Palavras-chave: Acidentes por Quedas. Idosos. Avaliação de Risco. Riscos Ambientais. AbstractIntroduction: The identification of environmental risk factors for falls is crucial for the prevention of this event in the elderly in the community. Objective: To present the main guidelines for the assessment of the environmental risks of falls among elderly people in the community. Method: Narrative review of literature with bibliographic research carried out by searching the LILACS, MEDLINE, SciELO and PubMed databases from August to November 2018. Results: The guidelines on the risks of falls in the elderly in the community recommend carrying out multifactorial assessment, including intrinsic and extrinsic risk factors, with emphasis on household factors. Several approaches and tools have been used to assess the risk of falls in the elderly in the community. Among the validated instruments for assessing residential environmental risks, most require home visits by health professionals to be applied. Conclusion: Multifactorial assessment is essential to identify the main risk factors for falls in the elderly in the community. The identification of hazards at home is one of the fundamental requirements for an efficient assessment.Keywords: Accidental Falls. Aged, Risk Assessment. Environmental Risks. ResumenIntroducción: La identificación de los factores de riesgo ambientales para las caídas es crucial para la prevención de este evento en los ancianos de la comunidad. Objetivo: Presentar las principales pautas para la evaluación de los riesgos ambientales de caídas entre las personas mayores en la comunidad. Método: revisión narrativa de la literatura con investigación bibliográfica realizada mediante la búsqueda en las bases de datos LILACS, MEDLINE, SciELO y PubMed de agosto a noviembre de 2018. Resultados: las pautas sobre los riesgos de caídas en los ancianos en la comunidad recomiendan llevar a cabo evaluación multifactorial, incluidos los factores de riesgo intrínsecos y extrínsecos, con énfasis en los factores del hogar. Se han utilizado varios enfoques y herramientas para evaluar el riesgo de caídas en los ancianos de la comunidad. Entre los instrumentos validados para evaluar los riesgos ambientales residenciales, la mayoría requiere que se apliquen visitas domiciliarias de profesionales de la salud. Conclusión: la evaluación multifactorial es esencial para identificar los principales factores de riesgo de caídas en los ancianos de la comunidad. La identificación de los peligros en el hogar es uno de los requisitos fundamentales para una evaluación eficiente.Palabras clave: Accidentes por Caídas. Personas Mayores. Evaluación de Riesgos. Riesgos Ambientales.


2019 ◽  
Vol 16 (4) ◽  
pp. 45-51
Author(s):  
Natalia O Khovasova ◽  
Anton V Naumov ◽  
Olga N Tkacheva ◽  
Victoriya I Moroz

Falls are a serious multi-factorial problem faced by the elderly persons which is associated with serious complications, loss of functional autonomy, disability and death. One of the common comorbidities among the elderly persons is arterial hypertension (AH) which increases the risk of falls. Aim. To study the risk factors for falls among patients with AH. Materials and methods. Examined 155 patients of geriatric department with the presence of at least one fall in the last year: 133 (85.8%) women (75,29±8.31 years) and 22 (14.2%) men (79,14±4.64 years). Risk of falls and risk factors of falls were assessed in patients with AH. Results. 148 (95.5%) patients had AH. The most common risk factors for hypertension in the elderly were atherosclerosis and decreased physical activity. Target organ lesions of varying severity were observed in all patients. In 25.7% of cases, BP figures outside the target values were noted. 18 (12.2%) patients received hypotensive therapy irregularly. On avera-ge, at admission, patients received of 2.06±0.63 anti-hypertensive drug. The frequency of falls in patients with hypertension made up 2.59±2.2, two or more falls happened in 91 persons (61.5%). According to the self-assessment risk of falls scale 131 (88.5%) patients had a high risk of falls. A high risk of falling in hospital (on the Morse scale) was identified in 63 (42.6%) patients. The most common risk factors for falls in patients with AH were previous falls in anamnesis, sensory de-ficit, imbalance, osteoarthritis. The CGA results demonstrate that patients with hypertension with blood pressure below the target values in comparison with the target and even high numbers of blood pressure have a higher prevalence of frailty, worse indicators of functional status, higher incidence and high risk of falls on the Morse scale. Conclusion. The most common risk factors for falls among patients with AH are previous falls in anamnesis, sensory deficit, imbalance, osteoarthritis. For patients with hypertension, low blood pressure is a predictor of high risk of falls and a worse prognosis. When blood pressure is below the target, there is a higher prevalence of frailty and worse indicators of functional status, which is a poor prognostic sign for the elderly.


2021 ◽  
Author(s):  
Thibaut Galvain ◽  
Ruaraidh Hill ◽  
Sarah Donegan ◽  
Paulo Lisboa ◽  
Gregory Y. H. Lip ◽  
...  

Abstract BackgroundAtrial fibrillation affects an estimated 33 million individuals worldwide and is a major cause of stroke, heart failure, and death. Anticoagulants substantially reduces risk of stroke but are also associated with an increased risk of bleeding and especially intracranial hemorrhages which are the most feared complication. Because of this many patients are not offered anticoagulants, particularly patients at risk of falls or with history of falls. It is unclear what anticoagulant treatment these patients should be offered, and the Liverpool AF-Falls project aims to investigate this area. This protocol for a systematic review and meta-analysis aims to define what is the most appropriate anticoagulant treatment option for the for the management of atrial fibrillation patients at risk of falls or with a history of falls. MethodsThis systematic review and meta-analysis will include randomized and non-randomized studies evaluating safety and efficacy of different anticoagulant treatments (vitamin K antagonist, non-vitamin K antagonist oral anti-coagulant, anti-platelet agent and no treatment). Bibliographic databases (Cochrane Central Register of Controlled Trials, MEDLINE, Embase, Scopus, CINAHL, Web of Science and ClinicalTrials.gov) will be searched according to a pre-specified search strategy. Titles, abstracts, and full texts will be assessed by two independent reviewers and disagreement resolved with a third independent reviewer. The Cochrane Risk of Bias tool 2 will be used to assess risk of bias in randomized trials and the Newcastle-Ottawa-Scale tool will be used for non-randomized studies. Pairwise meta-analysis based on the fixed and random-effects models will be conducted. Publication bias will be evaluated with a funnel plot and the Egger’s test. Heterogeneity will be assessed with the I2 statistic. If conditions for indirect comparison are met and sufficient data are available, a network meta-analysis will be conducted using frequentist and Bayesian methodologies. DiscussionThis review will be the first to summarize direct and indirect evidence on safety and efficacy of anticoagulant treatments in atrial fibrillation patients at risk of falls or with history of falls. The findings will be important to patients, clinicians, and health policy-makers to inform best practice in the use of these treatments. Systematic review registrationPROSPERO registry number: CRD42020201086


2020 ◽  
Vol 24 (1) ◽  
Author(s):  
Bruna Soares Vasques Blaz ◽  
Rosemeiry Capriata de Souza Azevedo ◽  
Daniela Luzia Zagoto Agulhó ◽  
Annelita Almeida Oliveira Reiners ◽  
Neuber José Segri ◽  
...  

ABSTRACT Objective: To analyze the association of the perception of the elderly on the risk factors for falls. Methods: An Analytical cross-sectional study with 190 elderly from the Healthy Longevity Program of a public university in Mato Grosso, from May to August 2016. The collection wasdone through a structured interview and vignettes. Performed descriptive and bivariate analyzes - Pearson chi-square test (x2) significance level of 5%. The crude and adjusted prevalence ratios (PR), with confidence intervals (95%), were also estimated, followed by Poisson multiple regression. Results: Of the participants, 64.2% had a satisfactory perception about the risk factors for falls. The prevalence of unsatisfactory risk perception was 105% higher in those with income from 1 to 3 minimum wages, 75% higher in those with low risk of falls and 46% higher in those who did not attend another social group. Conclusion and implications for the practice: A significant proportion of the elderly have an unsatisfactory risk perception for the risk factors for falls associated with low income, not attending another social group and the low risk of falls. Knowledge about the risk perception of falls in the elderly helps nurses to plan and implement fall prevention programs for this population.


Author(s):  
Francesc X. Marin-Gomez ◽  
Jacobo Mendioroz-Peña ◽  
Miguel-Angel Mayer ◽  
Leonardo Méndez-Boo ◽  
Núria Mora ◽  
...  

Nursing homes have accounted for a significant part of SARS-CoV-2 mortality, causing great social alarm. Using data collected from electronic medical records of 1,319,839 institutionalised and non-institutionalised persons ≥ 65 years, the present study investigated the epidemiology and differential characteristics between these two population groups. Our results showed that the form of presentation of the epidemic outbreak, as well as some risk factors, are different among the elderly institutionalised population with respect to those who are not. In addition to a twenty-fold increase in the rate of adjusted mortality among institutionalised individuals, the peak incidence was delayed by approximately three weeks. Having dementia was shown to be a risk factor for death, and, unlike the non-institutionalised group, neither obesity nor age were shown to be significantly associated with the risk of death among the institutionalised. These differential characteristics should be able to guide the actions to be taken by the health administration in the event of a similar infectious situation among institutionalised elderly people.


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